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Table of Pairwise Domain-Domain Interactions for the domain:
MHC_II_alpha

Interacting Domains ↕CD ↕ Accession (External Link)Description ↕
MHC_II_betapfam00969Class II histocompatibility antigen, beta domain.
igpfam00047Immunoglobulin domain. Ig: immunoglobulin (Ig) domain found in the Ig superfamily. The Ig superfamily is a heterogenous group of proteins, built on a common fold comprised of a sandwich of two beta sheets. Members of this group are components of immunoglobulin, neuroglia, cell surface glycoproteins, such as, T-cell receptors, CD2, CD4, CD8, and membrane glycoproteins, such as, butyrophilin and chondroitin sulfate proteoglycan core protein. A predominant feature of most Ig domains is a disulfide bridge connecting the two beta-sheets with a tryptophan residue packed against the disulfide bond.
C1-setpfam07654Immunoglobulin C1-set domain.
MHC_Ipfam00129Class I Histocompatibility antigen, domains alpha 1 and 2.
V-setpfam07686Immunoglobulin V-set domain. This domain is found in antibodies as well as neural protein P0 and CTL4 amongst others.
Myelin_MBPpfam01669Myelin basic protein.
MHC2-interactpfam09307CLIP, MHC2 interacting. Members of this family are found in class II invariant chain-associated peptide (CLIP), and are required for association with class II major histocompatibility complex (MHC) in the MHC class II processing pathway.
Orexinpfam02072Prepro-orexin.



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