Results for the gene: LRRK2

Results for Proteins associated with the Gene: LRRK2

LRRK2

120892

Q5S007 NP_940980

NCBI

Known Diseases associated with this Protein:

PARKINSON DISEASE 8 (PARK8)

			21 31 0 0 52

Tips:

The Domains on the Default View are decided by HMMER's search E-Value of the Protein against the Domain model.

Clicking a check box on the left will display or hide the corresponding domain(s).

To view the Protein page, either click on the protein links in the box to the left or the blue bar above the Protein's graphic.

Swiss-Prot Protein: Q5S007

Default View:

RefSeq Protein: NP_940980

Default View:

Domains found on the Proteins

Protein ↕	Domain ↕	Domain Accession ↕	Start ↕	End ↕	E-Value ↕
NP_940980	Rab35	cd04110	1331	1538	0.00079
NP_940980	Rab2	cd01866	1332	1507	0.0003
NP_940980	Rab8_Rab10_Rab13_lik	cd01867	1332	1507	0.0001
NP_940980	Rab30	cd04114	1332	1509	9.4e-07
NP_940980	Rab3	cd01865	1334	1508	2.1e-06
NP_940980	Rac1_like	cd01871	1334	1512	0.00019
NP_940980	RhoA_like	cd01870	1334	1517	0.00014
NP_940980	Rab33B_Rab33A	cd04115	1334	1515	0.0007
NP_940980	Rab	cd00154	1335	1506	1.1e-08
NP_940980	Ran	cd00877	1335	1511	3.5e-05
NP_940980	Rab6	cd01861	1335	1508	0.00042
NP_940980	Rab18	cd01863	1335	1500	0.00044
NP_940980	Rab1_Ypt1	cd01869	1335	1507	0.00032
NP_940980	Rab7	cd01862	1335	1510	0.00012
NP_940980	Rab26	cd04112	1335	1511	0.00065
NP_940980	Rab15	cd04117	1335	1501	0.00024
NP_940980	Rab4	cd04113	1335	1534	9.2e-07
NP_940980	Rab14	cd04122	1335	1507	0.00059
NP_940980	Rab27A	cd04127	1335	1508	8e-05
NP_940980	Ras_like_GTPase	cd00882	1339	1506	5e-22
NP_940980	PTKc_PDGFR_alpha	cd05105	1730	2138	0.00024
NP_940980	STKc_TAO1	cd06635	1851	2168	0.00011
NP_940980	STKc_PAK6	cd06659	1855	2154	8.2e-06
NP_940980	PTKc_FGFR1	cd05098	1856	2145	1.2e-05
NP_940980	STKc_PAK_I	cd06647	1857	2152	0.00071
NP_940980	STKc_myosinIIIB	cd06639	1859	2135	0.001
NP_940980	PTKc_PDGFR	cd05055	1860	2136	5.6e-05
NP_940980	STKc_myosinIIIA	cd06638	1861	2137	0.00029
NP_940980	PTKc_DDR2	cd05095	1863	2134	5e-05
NP_940980	PTKc_FGFR2	cd05101	1863	2143	7.2e-06
NP_940980	STKc_p38alpha_MAPK14	cd07877	1863	2183	0.00067
NP_940980	STKc_JNK	cd07850	1864	2197	0.00012
NP_940980	STKc_p38gamma_MAPK12	cd07880	1864	2204	0.00028
NP_940980	STKc_PAK	cd06614	1865	2144	2.6e-11
NP_940980	PTKc_EGFR_like	cd05057	1867	2148	4e-08
NP_940980	PTKc_TrkA	cd05092	1867	2142	0.00013
NP_940980	PTK_HER3	cd05111	1867	2136	3.4e-07
NP_940980	PKc_MKK7	cd06618	1867	2143	5e-07
NP_940980	STKc_MAP4K5	cd06646	1867	2133	1.2e-05
NP_940980	STKc_MAP4K3	cd06645	1867	2133	1.7e-05
NP_940980	STKc_p38	cd07851	1867	2199	9e-07
NP_940980	STKc_p38beta_MAPK11	cd07878	1867	2199	0.00053
NP_940980	PTKc_Csk_like	cd05039	1868	2135	1.4e-11
NP_940980	PTKc_FAK	cd05056	1868	2140	5.3e-09
NP_940980	PTKc_Chk	cd05083	1868	2135	5.7e-18
NP_940980	PTKc_Csk	cd05082	1868	2135	1e-08
NP_940980	PTKc_Trk	cd05049	1869	2134	2.3e-08
NP_940980	PTKc_EphR_A10	cd05064	1869	2136	3.5e-06
NP_940980	PTKc_FGFR4	cd05099	1869	2148	4.5e-07
NP_940980	PTKc_FGFR3	cd05100	1869	2175	0.00012
NP_940980	PTKc_Tie2	cd05088	1869	2154	2.6e-09
NP_940980	PTKc_EGFR	cd05108	1869	2171	5.6e-05
NP_940980	PTKc_HER4	cd05110	1869	2155	7.4e-06
NP_940980	PTKc_HER2	cd05109	1869	2148	1.4e-05
NP_940980	STKc_CDK12	cd07864	1869	2169	2.3e-05
NP_940980	PTKc_InsR_like	cd05032	1870	2134	2e-08
NP_940980	PTKc_EphR	cd05033	1870	2136	1.1e-08
NP_940980	PTKc_Musk	cd05050	1870	2134	1.2e-06
NP_940980	PTKc_FGFR	cd05053	1870	2137	2.9e-08
NP_940980	PTKc_Tec_like	cd05059	1870	2133	1.6e-09
NP_940980	PTKc_EphR_A	cd05066	1870	2136	3.1e-05
NP_940980	PTKc_Frk_like	cd05068	1870	2135	3.4e-16
NP_940980	PTKc_Lck_Blk	cd05067	1870	2135	4.4e-07
NP_940980	PTKc_Jak2_Jak3_rpt2	cd05081	1870	2136	2.9e-08
NP_940980	PTKc_Itk	cd05112	1870	2133	3.1e-10
NP_940980	PTKc_Tec_Rlk	cd05114	1870	2133	1.3e-08
NP_940980	PTKc_Btk_Bmx	cd05113	1870	2133	6.7e-09
NP_940980	STKc_TAO	cd06607	1870	2169	9.9e-06
NP_940980	PKc_MAPKK_Byr1_like	cd06620	1870	2135	5.6e-07
NP_940980	STKc_TNIK	cd06637	1870	2131	4.8e-05
NP_940980	STKc_Nek6_Nek7	cd08224	1870	2140	2.8e-08
NP_940980	STKc_ASK	cd06624	1871	2137	4.6e-07
NP_940980	STKc_TAO2	cd06634	1871	2183	7e-06
NP_940980	STKc_SLK	cd06643	1871	2143	1.5e-06
NP_940980	STKc_STK10_LOK	cd06644	1872	2152	1.1e-05
NP_940980	PTKc_Tie1	cd05089	1873	2156	2.3e-08
NP_940980	STKc_PKA	cd05580	1873	2132	1.6e-08
NP_940980	STKc_PDK1	cd05581	1873	2137	3.2e-10
NP_940980	PKc_MAPKK	cd06605	1873	2136	8.3e-08
NP_940980	STKc_MAP4K3_like	cd06613	1873	2129	3.9e-09
NP_940980	PKc_MKK5	cd06619	1873	2149	0.00084
NP_940980	PKc_MAPKK_PBS2_like	cd06622	1873	2192	4.1e-06
NP_940980	PKc_MKK3_6	cd06617	1873	2146	2.4e-06
NP_940980	STKc_PAK_II	cd06648	1873	2144	1.6e-05
NP_940980	STKc_ERK5	cd07855	1873	2158	9.1e-07
NP_940980	STKc_CDK9	cd07865	1873	2129	1.1e-05
NP_940980	PTK_CCK4	cd05046	1874	2134	0.00033
NP_940980	PTKc_EphR_A2	cd05063	1874	2138	1.9e-05
NP_940980	PTKc_EphR_B	cd05065	1874	2136	1.3e-05
NP_940980	PTKc_Src	cd05071	1874	2137	1.8e-07
NP_940980	PTKc_Ror1	cd05090	1874	2135	2.9e-05
NP_940980	PTKc_Ror2	cd05091	1874	2135	0.00028
NP_940980	PTKc_VEGFR3	cd05102	1874	2141	0.00089
NP_940980	PTKc_VEGFR2	cd05103	1874	2141	0.00031
NP_940980	PTKc_Srm_Brk	cd05148	1874	2135	1.5e-12
NP_940980	STKc_TEY_MAPK_plant	cd07858	1874	2208	5.4e-05
NP_940980	PTKc_Jak_rpt2	cd05038	1875	2136	1.3e-10
NP_940980	PTKc_Ror	cd05048	1875	2135	1.5e-05
NP_940980	PTKc_Abl	cd05052	1875	2136	1.3e-09
NP_940980	STKc_phototropin_lik	cd05574	1875	2115	0.0001
NP_940980	STKc_PRKX_like	cd05612	1875	2138	1.7e-05
NP_940980	STKc_MAST	cd05609	1875	2194	0.00075
NP_940980	STKc_MST3_like	cd06609	1875	2148	2.2e-09
NP_940980	PKc_MEK	cd06615	1875	2142	2.7e-05
NP_940980	PKc_MAPKK_plant_like	cd06623	1875	2137	9.6e-13
NP_940980	STKc_CDK8	cd07868	1875	2134	0.00012
NP_940980	STKc_CDC2L6	cd07867	1875	2155	5.2e-05
NP_940980	PKc_STE	cd05122	1876	2129	1.5e-12
NP_940980	STKc_GRK4_like	cd05605	1876	2176	9e-05
NP_940980	STKc_GRK6	cd05630	1876	2149	0.00066
NP_940980	STKc_MAPKKK	cd06606	1876	2128	9.3e-16
NP_940980	STKc_MEKK3	cd06651	1876	2128	3.2e-06
NP_940980	STKc_Pho85	cd07836	1876	2163	0.00041
NP_940980	STKc_CDK7	cd07841	1876	2147	7e-09
NP_940980	STKc_CDKL1_4	cd07847	1876	2163	1.1e-06
NP_940980	STKc_MPK1	cd07857	1876	2154	1e-05
NP_940980	STKc_CDK2_3	cd07860	1876	2163	0.00041
NP_940980	STKc_CDK10	cd07845	1876	2150	1.8e-07
NP_940980	STKc_Nek8	cd08220	1876	2138	4.1e-07
NP_940980	STKc_Nek5	cd08225	1876	2137	5.2e-05
NP_940980	STKc_FA2-like	cd08529	1876	2136	1.3e-09
NP_940980	PTKc_Src_like	cd05034	1877	2135	1.6e-13
NP_940980	PTKc_ALK_LTK	cd05036	1877	2134	5.3e-11
NP_940980	PTKc_InsR	cd05061	1877	2140	1.3e-06
NP_940980	PTKc_Fyn_Yrk	cd05070	1877	2135	1.8e-07
NP_940980	PTKc_Hck	cd05073	1877	2135	4.4e-09
NP_940980	PTKc_Yes	cd05069	1877	2135	6e-09
NP_940980	PTKc_Jak1_rpt2	cd05079	1877	2138	6.3e-05
NP_940980	PTKc_Lyn	cd05072	1877	2135	2.5e-08
NP_940980	PTKc_IGF-1R	cd05062	1877	2134	2.3e-06
NP_940980	STKc_myosinIII_like	cd06608	1877	2131	1.5e-06
NP_940980	PKc_MKK4	cd06616	1877	2145	8.5e-05
NP_940980	STKc_CDK1_like	cd07835	1877	2163	0.0003
NP_940980	STKc_CDK9_like	cd07840	1877	2129	1.9e-07
NP_940980	STKc_PCTAIRE_like	cd07844	1877	2163	0.00071
NP_940980	STKc_ERK1_2_like	cd07849	1877	2152	5.8e-06
NP_940980	STKc_MAPK4_6	cd07854	1877	2149	1.9e-05
NP_940980	STKc_Sty1_Hog1	cd07856	1877	2149	3.1e-06
NP_940980	STKc_PFTAIRE2	cd07870	1877	2162	0.00017
NP_940980	STKc_BUR1	cd07866	1877	2129	5.8e-05
NP_940980	STKc_CDK4_6_like	cd07838	1877	2129	5.2e-06
NP_940980	SPS1	COG0515	1877	2302	8.8e-33
NP_940980	STKc_cPKC_alpha	cd05615	1878	2191	0.00022
NP_940980	STKc_MAPKKK_Byr2_lik	cd06628	1878	2134	1.4e-06
NP_940980	STKc_CDKL2_3	cd07846	1878	2129	2.9e-07
NP_940980	STKc_NLK	cd07853	1878	2237	9.6e-08
NP_940980	STKc_CDK4	cd07863	1878	2162	0.00014
NP_940980	STKc_TDY_MAPK_plant	cd07859	1878	2176	0.00017
NP_940980	STKc_Nek1	cd08218	1878	2137	7.1e-05
NP_940980	STKc_Nek3	cd08219	1878	2137	5.6e-07
NP_940980	STKc_Nek6	cd08228	1878	2137	2e-05
NP_940980	STKc_Nek7	cd08229	1878	2137	2.3e-07
NP_940980	STKc_Nek10	cd08528	1878	2134	1.2e-05
NP_940980	PTK_Ryk	cd05043	1879	2137	5.1e-07
NP_940980	STKc_OSR1_SPAK	cd06610	1879	2129	9.1e-10
NP_940980	STKc_CDKL	cd07833	1879	2129	4.2e-07
NP_940980	STKc_CdkB_plant	cd07837	1879	2164	1.7e-06
NP_940980	STKc_MST4	cd06640	1880	2151	0.00029
NP_940980	STKc_MST3	cd06641	1880	2151	3.7e-05
NP_940980	STKc_STK25-YSK1	cd06642	1880	2148	7.5e-06
NP_940980	STKc_MST1_2	cd06612	1881	2131	2.7e-10
NP_940980	PKc_MAPKK_Pek1_like	cd06621	1881	2140	4.9e-05
NP_940980	STKc_MEKK3_like_1	cd06653	1881	2134	2.2e-05
NP_940980	PTKc_RET	cd05045	1882	2134	1.4e-05
NP_940980	STKc_MSK_N	cd05583	1882	2147	0.00062
NP_940980	STKc_p70S6K	cd05584	1882	2196	0.00024
NP_940980	STKc_cPKC	cd05587	1882	2196	2.1e-05
NP_940980	STKc_PKN	cd05589	1882	2190	8.3e-07
NP_940980	STKc_Yank1	cd05578	1882	2137	6.4e-08
NP_940980	STKc_cPKC_beta	cd05616	1882	2193	6.4e-05
NP_940980	STKc_MEKK4	cd06626	1882	2128	3e-10
NP_940980	STKc_Cdc7_like	cd06627	1882	2128	1.5e-10
NP_940980	STKc_Nek11	cd08222	1882	2134	0.00058
NP_940980	STKc_Nek4	cd08223	1882	2137	1.9e-06
NP_940980	STKc_CNK2-like	cd08530	1882	2137	9.5e-11
NP_940980	PTKc	cd00192	1883	2133	1.3e-14
NP_940980	PTKc_Ack_like	cd05040	1883	2134	1.7e-11
NP_940980	PTKc_c-ros	cd05044	1883	2134	2.7e-08
NP_940980	PTKc_Fes_like	cd05041	1883	2134	2.6e-13
NP_940980	PTKc_Tyk2_rpt2	cd05080	1883	2137	6e-08
NP_940980	PTKc_Zap-70	cd05115	1883	2137	7.8e-07
NP_940980	STKc_PKC	cd05570	1883	2132	1e-08
NP_940980	STKc_CDK8_like	cd07842	1883	2129	0.00021
NP_940980	PTKc_Axl_like	cd05035	1884	2136	7.7e-05
NP_940980	PTKc_Tie	cd05047	1884	2137	1.7e-08
NP_940980	PTKc_Met_Ron	cd05058	1884	2138	1.2e-05
NP_940980	PTKc_Tyro3	cd05074	1884	2136	6.3e-05
NP_940980	PTKc_Fer	cd05085	1884	2134	5.2e-08
NP_940980	STKc_PKB	cd05571	1884	2171	1.5e-05
NP_940980	STKc_SGK	cd05575	1884	2205	9.7e-05
NP_940980	STKc_RSK_N	cd05582	1884	2182	0.00047
NP_940980	STKc_aPKC	cd05588	1884	2195	0.00012
NP_940980	STKc_PKB_gamma	cd05593	1884	2177	0.00016
NP_940980	STKc_PKB_beta	cd05595	1884	2202	0.00039
NP_940980	STKc_nPKC_theta_delt	cd05592	1884	2194	2e-05
NP_940980	STKc_PKB_alpha	cd05594	1884	2195	0.00012
NP_940980	STKc_SGK1	cd05602	1884	2197	0.00055
NP_940980	STKc_SGK2	cd05603	1884	2206	2.4e-05
NP_940980	STKc_beta_ARK	cd05606	1884	2148	1.6e-06
NP_940980	STKc_nPKC_theta	cd05619	1884	2170	4.5e-06
NP_940980	STKc_nPKC_eta	cd05590	1884	2201	0.00036
NP_940980	STKc_GRK3	cd05633	1884	2149	0.00014
NP_940980	STKc_nPKC_epsilon	cd05591	1884	2193	5.8e-05
NP_940980	STKc_MEKK1	cd06630	1884	2130	1.2e-06
NP_940980	STKc_MEKK1_plant	cd06632	1884	2128	2.8e-09
NP_940980	STKc_YSK4	cd06631	1884	2132	3e-07
NP_940980	STKc_MAPKKK_Bck1_lik	cd06629	1884	2130	2.8e-06
NP_940980	STKc_MEKK3_like	cd06625	1884	2134	4.7e-12
NP_940980	STKc_MEKK2	cd06652	1884	2117	0.00053
NP_940980	STKc_NAK1_like	cd06917	1884	2145	4.1e-07
NP_940980	STKc_CDK_like	cd07829	1884	2129	3.4e-09
NP_940980	STKc_MAPK	cd07834	1884	2158	7.1e-08
NP_940980	STKc_Nek	cd08215	1884	2134	2.2e-12
NP_940980	STKc_Nek9	cd08221	1884	2134	2e-08
NP_940980	STKc_Nek2	cd08217	1884	2137	1e-07
NP_940980	PKc	cd00180	1885	2132	2e-53
NP_940980	PTKc_Aatyk	cd05042	1885	2134	2.5e-05
NP_940980	PTK_Jak_rpt1	cd05037	1885	2133	5.3e-05
NP_940980	PTKc_Syk_like	cd05060	1885	2138	1.8e-09
NP_940980	PTK_Jak2_Jak3_rpt1	cd05078	1885	2133	2.8e-06
NP_940980	PTKc_Fes	cd05084	1885	2134	2e-07
NP_940980	PTKc_Syk	cd05116	1885	2137	8.2e-08
NP_940980	STKc_CMGC	cd05118	1885	2129	4.4e-10
NP_940980	STKc_AGC	cd05123	1885	2129	2.2e-11
NP_940980	STKc_cGK_PKG	cd05572	1885	2136	2.3e-07
NP_940980	STKc_GRK	cd05577	1885	2118	3.2e-06
NP_940980	STKc_MAST_like	cd05579	1885	2130	1.2e-08
NP_940980	STKc_YPK1_like	cd05585	1885	2168	0.00023
NP_940980	STKc_GRK7	cd05607	1885	2148	0.00017
NP_940980	STKc_GRK1	cd05608	1885	2158	2.9e-06
NP_940980	STKc_SLK_like	cd06611	1885	2140	3.1e-06
NP_940980	STKc_MOK	cd07831	1885	2129	4.9e-05
NP_940980	STKc_CCRK	cd07832	1885	2138	8.6e-08
NP_940980	STKc_CDK5	cd07839	1885	2163	5e-05
NP_940980	STKc_MAK_like	cd07830	1885	2129	1.6e-08
NP_940980	STKc_MAPK15	cd07852	1885	2167	4.5e-06
NP_940980	STKc_CDC2L1	cd07843	1887	2129	1.6e-05
NP_940980	COG4886	COG4886	938	1359	0.00067
NP_940980	Ras	pfam00071	1336	1502	7e-06
NP_940980	Pkinase	pfam00069	1879	2132	5.8e-35
NP_940980	RAB	smart00175	1335	1504	3.3e-05
NP_940980	Miro	pfam08477	1336	1455	3.2e-39
NP_940980	Pkinase_Tyr	pfam07714	1875	2132	2.1e-19
NP_940980	TyrKc	smart00219	1875	2132	3.6e-20
NP_940980	STYKc	smart00221	1875	2134	1.2e-35
NP_940980	S_TKc	smart00220	1889	2140	7.2e-34

Please Cite: Peterson, T.A., Adadey, A., Santana-Cruz ,I., Sun, Y., Winder A, Kann, M.G., (2010) DMDM: Domain Mapping of Disease Mutations. Bioinformatics 26 (19), 2458-2459.

DMDM_info@umbc.edu | 1000 Hilltop Circle, Baltimore, MD 21250 | Department of Biological Sciences | Phone: 410-455-2258