Results for the gene: ERBB2

Results for Proteins associated with the Gene: ERBB2

ERBB2

2064

P04626 NP_001005862 NP_004439

NCBI

Known Diseases associated with this Protein:

ADENOCARCINOMA OF LUNG, SOMATIC

GASTRIC CANCER, SOMATIC

GLIOBLASTOMA, SOMATIC

OVARIAN CANCER, SOMATIC

			8 14 8 8 6

Tips:

The Domains on the Default View are decided by HMMER's search E-Value of the Protein against the Domain model.

Clicking a check box on the left will display or hide the corresponding domain(s).

To view the Protein page, either click on the protein links in the box to the left or the blue bar above the Protein's graphic.

Swiss-Prot Protein: P04626

Identical to: NP_004439

Default View:

RefSeq Protein: NP_001005862

Default View:

RefSeq Protein: NP_004439

Default View:

Domains found on the Proteins

Protein ↕	Domain ↕	Domain Accession ↕	Start ↕	End ↕	E-Value ↕
NP_004439	FU	cd00064	510	561	2.8e-10
NP_004439	FU	cd00064	562	624	5.2e-14
NP_004439	PTKc_Kit	cd05104	610	980	5e-12
NP_004439	PTKc_PDGFR_beta	cd05107	610	981	3.4e-09
NP_004439	PTKc_VEGFR	cd05054	614	983	4.1e-23
NP_004439	PTKc_VEGFR3	cd05102	657	983	1.4e-21
NP_004439	PTKc_VEGFR2	cd05103	661	983	3.9e-14
NP_004439	PTKc_CSF-1R	cd05106	684	981	8.6e-14
NP_004439	PTKc_PDGFR_alpha	cd05105	685	982	8.2e-12
NP_004439	STKc_PAK1	cd06654	692	998	9.7e-06
NP_004439	STKc_PAK_I	cd06647	693	995	1e-05
NP_004439	STKc_PAK2	cd06655	693	998	2.1e-05
NP_004439	STKc_PAK3	cd06656	693	999	3e-06
NP_004439	PTKc_FGFR1	cd05098	701	984	2.1e-37
NP_004439	PKc_MKK7	cd06618	704	992	4.4e-08
NP_004439	STKc_myosinIIIB	cd06639	704	978	0.00025
NP_004439	PTK_Tyk2_rpt1	cd05076	705	977	3.7e-05
NP_004439	PTKc_FGFR2	cd05101	705	993	6.3e-42
NP_004439	PTKc_FGFR3	cd05100	706	1017	3.8e-39
NP_004439	PTKc_FGFR4	cd05099	706	997	1.6e-44
NP_004439	STKc_myosinIIIA	cd06638	706	977	1.8e-05
NP_004439	STKc_p38	cd07851	706	1013	3.3e-06
NP_004439	STKc_PAK	cd06614	707	990	6.5e-10
NP_004439	STKc_TAO	cd06607	707	1010	0.00056
NP_004439	PTKc_DDR	cd05051	708	978	2.2e-27
NP_004439	STKc_STK10_LOK	cd06644	708	995	0.00012
NP_004439	STKc_PAK_II	cd06648	708	990	0.00049
NP_004439	PTKc_PDGFR	cd05055	709	980	1.3e-17
NP_004439	STKc_MAP4K3	cd06645	710	976	0.00034
NP_004439	STKc_MAP4K5	cd06646	710	977	0.00024
NP_004439	STKc_CDK10	cd07845	710	999	5.6e-05
NP_004439	PTK_Ryk	cd05043	712	980	5e-25
NP_004439	PTKc_FAK	cd05056	712	984	9.4e-85
NP_004439	PTKc_EGFR_like	cd05057	712	990	2.4e-216
NP_004439	PTKc_Lck_Blk	cd05067	712	976	1.5e-48
NP_004439	PTKc_Src	cd05071	712	981	1.5e-46
NP_004439	PTKc_Lyn	cd05072	712	979	1.2e-41
NP_004439	PTKc_Hck	cd05073	712	979	7.2e-41
NP_004439	PTKc_Fyn_Yrk	cd05070	712	979	3e-48
NP_004439	PTKc_Tie2	cd05088	712	1002	2.8e-35
NP_004439	PTKc_Yes	cd05069	712	979	2.7e-43
NP_004439	PTKc_HER2	cd05109	712	990	4.1e-250
NP_004439	PTKc_HER4	cd05110	712	1013	4.6e-209
NP_004439	PTK_HER3	cd05111	712	990	2.3e-158
NP_004439	PTKc_EGFR	cd05108	712	1026	4.9e-230
NP_004439	STKc_ASK	cd06624	712	978	4.5e-07
NP_004439	STKc_Sty1_Hog1	cd07856	712	1021	0.00016
NP_004439	PTKc_ALK_LTK	cd05036	713	978	1.6e-55
NP_004439	PTKc_Ror	cd05048	713	979	2.4e-34
NP_004439	STKc_MAP4K4_6	cd06636	713	979	0.00028
NP_004439	PTKc_InsR_like	cd05032	714	978	1.2e-55
NP_004439	PTKc_Src_like	cd05034	714	979	9.6e-62
NP_004439	PTKc_Csk_like	cd05039	714	979	3.7e-39
NP_004439	PTK_CCK4	cd05046	714	978	7.5e-19
NP_004439	PTKc_Trk	cd05049	714	978	1.3e-35
NP_004439	PTKc_Csk	cd05082	714	979	9.9e-52
NP_004439	PTKc_Chk	cd05083	714	979	1.1e-52
NP_004439	STKc_SLK	cd06643	714	993	1.6e-05
NP_004439	PTKc_EphR	cd05033	715	980	3.7e-64
NP_004439	PTKc_Jak_rpt2	cd05038	715	980	5.9e-66
NP_004439	PTKc_Musk	cd05050	715	978	2.6e-36
NP_004439	PTKc_Abl	cd05052	715	980	6.7e-69
NP_004439	PTKc_FGFR	cd05053	715	981	3.1e-49
NP_004439	PTKc_EphR_A2	cd05063	715	980	6.3e-63
NP_004439	PTKc_EphR_A10	cd05064	715	980	3.9e-45
NP_004439	PTKc_EphR_B	cd05065	715	980	1.4e-60
NP_004439	PTKc_EphR_A	cd05066	715	980	2.9e-62
NP_004439	PTKc_Tec_like	cd05059	715	977	7.1e-52
NP_004439	PTKc_Frk_like	cd05068	715	979	4.8e-71
NP_004439	PTKc_Jak1_rpt2	cd05079	715	980	1e-42
NP_004439	PTKc_Jak2_Jak3_rpt2	cd05081	715	980	2e-52
NP_004439	PTKc_Ror1	cd05090	715	979	3.6e-34
NP_004439	PTKc_TrkA	cd05092	715	986	2.9e-33
NP_004439	PTKc_TrkC	cd05094	715	988	2.6e-12
NP_004439	PTKc_DDR2	cd05095	715	978	5.7e-28
NP_004439	PTKc_DDR1	cd05096	715	978	1.6e-21
NP_004439	PTKc_DDR_like	cd05097	715	978	7.2e-29
NP_004439	PTKc_Itk	cd05112	715	977	1.5e-62
NP_004439	PTKc_Btk_Bmx	cd05113	715	977	8.8e-60
NP_004439	PTKc_Tec_Rlk	cd05114	715	977	7.4e-62
NP_004439	PTKc_TrkB	cd05093	715	988	2.3e-28
NP_004439	PKc_MKK4	cd06616	715	995	1.5e-06
NP_004439	STKc_myosinIII_like	cd06608	715	977	9.2e-07
NP_004439	PKc_MAPKK_Byr1_like	cd06620	715	987	1.4e-07
NP_004439	STKc_TNIK	cd06637	715	977	9.1e-05
NP_004439	PKc_MEK2	cd06649	715	1030	6.6e-05
NP_004439	PKc_MEK1	cd06650	715	1041	9.6e-06
NP_004439	PTKc_Srm_Brk	cd05148	716	979	1.8e-50
NP_004439	STKc_OSR1_SPAK	cd06610	716	976	8.3e-09
NP_004439	STKc_MST1_2	cd06612	716	946	2.3e-09
NP_004439	STKc_MAP4K3_like	cd06613	716	976	6.2e-08
NP_004439	STKc_PCTAIRE_like	cd07844	716	1005	1.9e-05
NP_004439	STKc_PFTAIRE1	cd07869	716	1026	0.00054
NP_004439	STKc_PFTAIRE2	cd07870	716	1031	3e-06
NP_004439	PTKc_InsR	cd05061	717	989	4.9e-41
NP_004439	PTKc_Ror2	cd05091	717	979	2.7e-24
NP_004439	STKc_MSK_N	cd05583	717	1026	1.6e-05
NP_004439	STKc_MST4	cd06640	717	1008	9.6e-07
NP_004439	STKc_MST3	cd06641	717	997	9.3e-07
NP_004439	STKc_MEKK3	cd06651	717	979	6e-09
NP_004439	STKc_MEKK2	cd06652	717	978	2.3e-05
NP_004439	STKc_MEKK3_like_1	cd06653	717	978	2.7e-05
NP_004439	STKc_STK25-YSK1	cd06642	717	998	2.7e-08
NP_004439	PTKc_Tie1	cd05089	718	1001	1e-35
NP_004439	STKc_PKA	cd05580	718	979	4.3e-05
NP_004439	STKc_MAST	cd05609	718	1032	0.00037
NP_004439	STKc_PRKX_like	cd05612	718	1021	7.1e-05
NP_004439	PKc_MAPKK	cd06605	718	982	3e-09
NP_004439	PKc_MKK3_6	cd06617	718	992	2.2e-07
NP_004439	PKc_MKK5	cd06619	718	1012	6.2e-05
NP_004439	STKc_MST3_like	cd06609	718	958	1.9e-08
NP_004439	PKc_MEK	cd06615	718	989	1.6e-05
NP_004439	PKc_MAPKK_Pek1_like	cd06621	718	989	8.6e-05
NP_004439	PKc_MAPKK_plant_like	cd06623	718	982	7.8e-12
NP_004439	STKc_MEKK3_like	cd06625	718	978	5.5e-10
NP_004439	PKc_MAPKK_PBS2_like	cd06622	718	1027	3.8e-06
NP_004439	STKc_NAK1_like	cd06917	718	977	6.6e-07
NP_004439	STKc_CdkB_plant	cd07837	718	1006	4.1e-06
NP_004439	STKc_CDKL1_4	cd07847	718	1014	1.3e-05
NP_004439	STKc_CDK12	cd07864	718	1005	0.00012
NP_004439	STKc_CDKL2_3	cd07846	718	977	0.00095
NP_004439	STKc_Nek6	cd08228	718	982	6.2e-05
NP_004439	STKc_Nek7	cd08229	718	981	8.7e-07
NP_004439	STKc_Nek6_Nek7	cd08224	718	985	1.3e-06
NP_004439	SPS1	COG0515	718	1176	2.5e-27
NP_004439	PTKc_RET	cd05045	719	983	7.1e-51
NP_004439	PTKc_IGF-1R	cd05062	719	978	5.8e-38
NP_004439	PKc_STE	cd05122	719	976	7e-12
NP_004439	STKc_Yank1	cd05578	719	979	1.9e-06
NP_004439	STKc_cPKC	cd05587	719	1047	9.4e-05
NP_004439	STKc_GRK4_like	cd05605	719	1013	8.1e-06
NP_004439	STKc_MSK1_N	cd05613	719	1006	1.7e-05
NP_004439	STKc_MSK2_N	cd05614	719	1052	7e-06
NP_004439	STKc_cPKC_alpha	cd05615	719	1034	0.00021
NP_004439	STKc_GRK6	cd05630	719	1002	0.0006
NP_004439	STKc_GRK4	cd05631	719	1035	0.00061
NP_004439	STKc_GRK5	cd05632	719	1008	0.00067
NP_004439	STKc_MAPKKK	cd06606	719	977	1.9e-15
NP_004439	STKc_MAPKKK_Byr2_lik	cd06628	719	978	2.3e-08
NP_004439	STKc_MEKK1	cd06630	719	977	8.8e-08
NP_004439	STKc_YSK4	cd06631	719	977	4e-09
NP_004439	STKc_Cdc7_like	cd06627	719	973	5.3e-12
NP_004439	STKc_CCRK	cd07832	719	970	2e-07
NP_004439	STKc_Pho85	cd07836	719	1031	0.00013
NP_004439	STKc_MAPK	cd07834	719	1012	4.6e-06
NP_004439	STKc_CDK5	cd07839	719	1005	0.00014
NP_004439	STKc_CDK7	cd07841	719	973	4.2e-06
NP_004439	STKc_NLK	cd07853	719	1043	0.00069
NP_004439	STKc_TDY_MAPK_plant	cd07859	719	1048	0.00071
NP_004439	STKc_CDK2_3	cd07860	719	1005	0.00033
NP_004439	STKc_CDK4	cd07863	719	1005	0.00031
NP_004439	STKc_Nek2	cd08217	719	979	1.4e-06
NP_004439	STKc_Nek1	cd08218	719	978	3.9e-05
NP_004439	STKc_Nek3	cd08219	719	978	3.3e-08
NP_004439	STKc_Nek4	cd08223	719	978	2e-05
NP_004439	STKc_Nek5	cd08225	719	978	3.1e-05
NP_004439	STKc_Nek8	cd08220	719	978	9.9e-06
NP_004439	STKc_Nek9	cd08221	719	978	3.9e-05
NP_004439	STKc_Nek10	cd08528	719	978	0.00021
NP_004439	PTKc_Axl_like	cd05035	720	980	1.6e-55
NP_004439	PTKc_Axl	cd05075	720	980	4.2e-42
NP_004439	PTKc_Tyk2_rpt2	cd05080	720	981	1.5e-27
NP_004439	PTKc_Tyro3	cd05074	720	980	2.7e-49
NP_004439	STKc_CMGC	cd05118	720	969	1.2e-07
NP_004439	STKc_PKN	cd05589	720	1031	0.00022
NP_004439	STKc_MAPKKK_Bck1_lik	cd06629	720	977	5.8e-07
NP_004439	STKc_CDK_like	cd07829	720	977	2.5e-06
NP_004439	STKc_MOK	cd07831	720	976	1.4e-05
NP_004439	STKc_CDK9_like	cd07840	720	986	9.8e-08
NP_004439	STKc_CDK4_6_like	cd07838	720	924	2.1e-05
NP_004439	STKc_CDK1_like	cd07835	720	1005	1.9e-06
NP_004439	STKc_MEKK1_plant	cd06632	721	973	8.9e-08
NP_004439	STKc_Nek	cd08215	721	978	9.1e-12
NP_004439	STKc_Nek11	cd08222	721	977	1.1e-05
NP_004439	STKc_MEKK4	cd06626	722	977	1.2e-06
NP_004439	STKc_CDK8_like	cd07842	722	1005	0.00031
NP_004439	STKc_FA2-like	cd08529	722	978	9e-08
NP_004439	STKc_RSK_N	cd05582	723	1053	1.4e-05
NP_004439	STKc_PDK1	cd05581	723	976	1.8e-09
NP_004439	STKc_p70S6K	cd05584	723	1035	3e-06
NP_004439	STKc_MAK_like	cd07830	723	946	1.4e-05
NP_004439	STKc_CNK2-like	cd08530	723	978	1e-06
NP_004439	PTKc	cd00192	724	977	1e-121
NP_004439	PTK_Jak_rpt1	cd05037	724	977	1.5e-10
NP_004439	PTKc_Ack_like	cd05040	724	978	2.7e-78
NP_004439	PTKc_Fes_like	cd05041	724	978	1.6e-42
NP_004439	PTKc_Aatyk	cd05042	724	975	2.4e-12
NP_004439	PTKc_c-ros	cd05044	724	978	1.3e-51
NP_004439	PTKc_Tie	cd05047	724	981	8.2e-42
NP_004439	PTKc_Met_Ron	cd05058	724	982	4.8e-71
NP_004439	PTKc_Syk_like	cd05060	724	981	1.9e-90
NP_004439	PTK_Jak1_rpt1	cd05077	724	977	2.2e-07
NP_004439	PTK_Jak2_Jak3_rpt1	cd05078	724	977	9.1e-11
NP_004439	PTKc_Fes	cd05084	724	978	3e-45
NP_004439	PTKc_Fer	cd05085	724	978	6.9e-51
NP_004439	PTKc_Aatyk1_Aatyk3	cd05087	724	978	8.5e-11
NP_004439	PTKc_Aatyk2	cd05086	724	978	2.7e-07
NP_004439	PTKc_Syk	cd05116	724	981	1.3e-62
NP_004439	STKc_PKB	cd05571	724	1058	0.00015
NP_004439	STKc_nPKC_theta_delt	cd05592	724	1035	0.00013
NP_004439	STKc_nPKC_theta	cd05619	724	1026	4.5e-05
NP_004439	STKc_SGK2	cd05603	724	1037	0.00064
NP_004439	PKc	cd00180	726	976	3e-53
NP_004439	PTKc_Zap-70	cd05115	726	981	2.7e-63
NP_004439	STKc_AGC	cd05123	726	979	1e-06
NP_004439	STKc_cGK_PKG	cd05572	726	944	0.0004
NP_004439	STKc_MAST_like	cd05579	726	951	4.8e-06
NP_004439	STKc_GRK	cd05577	726	1034	0.00083
NP_004439	STKc_GRK1	cd05608	726	1007	7.4e-05
NP_004439	Recep_L_domain	pfam01030	52	173	3.1e-50
NP_004439	Furin-like	pfam00757	189	343	1.5e-69
NP_004439	Recep_L_domain	pfam01030	366	486	1.1e-28
NP_004439	Pkinase	pfam00069	720	976	5.5e-33
NP_004439	FU	smart00261	232	276	2.2e-07
NP_004439	FU	smart00261	501	552	5.5e-09
NP_004439	FU	smart00261	557	606	3.3e-09
NP_004439	Pkinase_Tyr	pfam07714	720	976	1.1e-131
NP_004439	TyrKc	smart00219	720	976	5.9e-128
NP_004439	STYKc	smart00221	720	987	7.1e-47
NP_004439	S_TKc	smart00220	730	980	9.9e-37
NP_004439	KIND	smart00750	807	1002	0.00045

Please Cite: Peterson, T.A., Adadey, A., Santana-Cruz ,I., Sun, Y., Winder A, Kann, M.G., (2010) DMDM: Domain Mapping of Disease Mutations. Bioinformatics 26 (19), 2458-2459.

DMDM_info@umbc.edu | 1000 Hilltop Circle, Baltimore, MD 21250 | Department of Biological Sciences | Phone: 410-455-2258