Results for the protein: NP

Results for the Protein: NP_001193674

332078492

7173

TPO

NCBI

thyroid peroxidase isoform b precursor [Homo sapiens]

Known Diseases associated with this Protein:
THYROID DYSHORMONOGENESIS 2A

6

10

6

10

0

Tips:

The Domains on the Default View are decided by the Domain's E-Value.

Clicking a check box will display or hide the correlated domain.

To view the Gene page, either click on the link to the left or the blue bar above the Protein's graphic.

Default View: An_peroxidase - pfam03098 CCP - smart00032 CCP - cd00033 EGF_CA - smart00179 EGF_CA - cd00054 EGF_CA - pfam07645 EGF - cd00053 EGF - smart00181 EGF - pfam00008	RefSeq Protein: NP_001193674 Default View:

Domains found on the Protein

Domain ↕	CD Accession ↕	E-Value ↕	Start ↕	End ↕
EGF_CA	cd00054	3.6e-14	739	782
EGF	cd00053	7.2e-10	742	782
An_peroxidase	pfam03098	3.7e-192	151	652
EGF	pfam00008	2.3e-05	743	780
CCP	smart00032	1.2e-10	685	737
EGF_CA	pfam07645	3.3e-13	739	781
EGF_CA	smart00179	8.8e-15	739	782
EGF	smart00181	2.7e-10	742	782

Source ↕	Mut_ID ↕	Class ↕	HGVS ↕	Disease ↕
dbSNP	rs4927611	Polymorphism	p.ALA257SER	N/A
dbSNP	rs2280132	Polymorphism	p.ALA373SER	N/A
dbSNP	rs1126797	Polymorphism	p.ASP609GLU	N/A
dbSNP	rs114796303	Polymorphism	p.LEU529PHE	N/A
dbSNP	rs28991293	Polymorphism	p.LEU736PRO	N/A
dbSNP	rs13431173	Polymorphism	p.MET649VAL	N/A
dbSNP	rs2175977	Polymorphism	p.SER398THR	N/A
dbSNP	rs732609	Polymorphism	p.THR668PRO	N/A
dbSNP	rs1126799	Polymorphism	p.VAL790ALA	N/A
dbSNP	rs10189135	Polymorphism	p.VAL561MET	N/A
OMIM	606765.0009	Disease	p.ARG591GLN	THYROID DYSHORMONOGENESIS 2A
OMIM	606765.0012	Disease	p.ARG636TRP	THYROID DYSHORMONOGENESIS 2A
OMIM	606765.0014	Disease	p.GLN603GLU	THYROID DYSHORMONOGENESIS 2A
OMIM	606765.0007	Disease	p.GLU742LYS	THYROID DYSHORMONOGENESIS 2A
OMIM	606765.0004	Disease	p.ILE447PHE	THYROID DYSHORMONOGENESIS 2A
OMIM	606765.0005	Disease	p.TYR453ASP	THYROID DYSHORMONOGENESIS 2A

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