Results for the gene: KIT

Results for Proteins associated with the Gene: KIT

KIT

3815

P10721 NP_001087241 NP_000213

NCBI

Known Diseases associated with this Protein:

GASTROINTESTINAL STROMAL TUMOR (GIST)

GASTROINTESTINAL STROMAL TUMOR, FAMILIAL

GASTROINTESTINAL STROMAL TUMOR, SOMATIC

GERM CELL TUMOR, SOMATIC

LEUKEMIA, ACUTE MYELOID

MAST CELL DISEASE, SYSTEMIC

MAST CELL LEUKEMIA

MASTOCYTOSIS WITH ASSOCIATED HEMATOLOGIC DISORDER, INCLUDED;;

MASTOCYTOSIS, ADULT SPORADIC, INCLUDE

MASTOCYTOSIS, SPORADIC, CHILDHOOD-ONSET

PIEBALD TRAIT (PBT)

PIEBALDISM

PIEBALDISM WITH SENSORINEURAL DEAFNESS

PIEBALDISM, PROGRESSIVE

			43 16 30 2 27

Tips:

The Domains on the Default View are decided by HMMER's search E-Value of the Protein against the Domain model.

Clicking a check box on the left will display or hide the corresponding domain(s).

To view the Protein page, either click on the protein links in the box to the left or the blue bar above the Protein's graphic.

Swiss-Prot Protein: P10721

Identical to: NP_000213

Default View:

RefSeq Protein: NP_001087241

Default View:

RefSeq Protein: NP_000213

Default View:

Domains found on the Proteins

Protein ↕	Domain ↕	Domain Accession ↕	Start ↕	End ↕	E-Value ↕
NP_000213	Ig4_SCFR_like	cd04975	311	411	5e-60
NP_000213	Ig4_PDGFR-alpha	cd05859	311	411	1.3e-10
NP_000213	Ig4_SCFR	cd05860	311	411	3.5e-77
NP_000213	PTKc_CSF-1R	cd05106	550	929	3.8e-215
NP_000213	PTKc_PDGFR	cd05055	553	928	1.3e-301
NP_000213	PTKc_Kit	cd05104	553	928
NP_000213	PTKc_PDGFR_alpha	cd05105	553	930	2.8e-168
NP_000213	PTKc_PDGFR_beta	cd05107	553	929	1.4e-156
NP_000213	PTKc_FGFR1	cd05098	571	935	2e-90
NP_000213	PTKc_FGFR2	cd05101	575	935	2.8e-93
NP_000213	PTKc_FGFR	cd05053	576	929	4.5e-117
NP_000213	PTKc_FGFR4	cd05099	576	945	6.5e-98
NP_000213	PTKc_FGFR3	cd05100	576	974	4.3e-90
NP_000213	PTKc_EGFR	cd05108	576	972	6.3e-14
NP_000213	PTKc_VEGFR	cd05054	581	931	4e-142
NP_000213	PTKc_EGFR_like	cd05057	581	938	7.7e-33
NP_000213	PTKc_VEGFR3	cd05102	581	931	4.2e-135
NP_000213	PTKc_VEGFR2	cd05103	581	931	7.5e-132
NP_000213	PTKc_InsR_like	cd05032	582	926	2.5e-56
NP_000213	PTKc_Src_like	cd05034	582	927	1.3e-52
NP_000213	PTKc_ALK_LTK	cd05036	582	926	2.1e-43
NP_000213	PTKc_Csk_like	cd05039	582	927	1.3e-32
NP_000213	PTKc_Abl	cd05052	582	928	3.8e-47
NP_000213	PTKc_FAK	cd05056	582	932	2.1e-39
NP_000213	PTKc_InsR	cd05061	582	937	2.1e-43
NP_000213	PTKc_IGF-1R	cd05062	582	926	6.4e-39
NP_000213	PTKc_Lck_Blk	cd05067	582	927	6.5e-36
NP_000213	PTKc_Frk_like	cd05068	582	927	4.2e-52
NP_000213	PTKc_Yes	cd05069	582	927	1.8e-31
NP_000213	PTKc_Fyn_Yrk	cd05070	582	927	7.7e-32
NP_000213	PTKc_Src	cd05071	582	929	9.5e-29
NP_000213	PTKc_Lyn	cd05072	582	927	7.3e-38
NP_000213	PTKc_Hck	cd05073	582	927	2.6e-40
NP_000213	PTKc_Csk	cd05082	582	927	7.9e-31
NP_000213	PTKc_Chk	cd05083	582	927	4.2e-39
NP_000213	PTKc_Tie1	cd05089	582	952	3.8e-49
NP_000213	PTKc_Srm_Brk	cd05148	582	927	6.3e-35
NP_000213	PTK_CCK4	cd05046	583	926	5.8e-20
NP_000213	PTKc_Trk	cd05049	583	926	6.5e-43
NP_000213	PTKc_Musk	cd05050	583	926	1.1e-64
NP_000213	PTKc_DDR	cd05051	583	926	8.4e-28
NP_000213	PTKc_EphR_A2	cd05063	583	928	2.5e-24
NP_000213	PTKc_EphR_A10	cd05064	583	928	5.3e-17
NP_000213	PTKc_Ror1	cd05090	583	927	3.5e-32
NP_000213	PTKc_TrkA	cd05092	583	934	3.2e-36
NP_000213	PTKc_TrkB	cd05093	583	936	1.9e-26
NP_000213	PTKc_TrkC	cd05094	583	938	1e-17
NP_000213	PTKc_DDR2	cd05095	583	926	1.1e-32
NP_000213	PTKc_Ror	cd05048	583	927	4.7e-44
NP_000213	PTKc_DDR1	cd05096	583	926	1.5e-35
NP_000213	PTKc_DDR_like	cd05097	583	926	6.8e-35
NP_000213	PTKc_Ror2	cd05091	583	927	6.1e-31
NP_000213	PTKc_EphR	cd05033	584	928	4e-24
NP_000213	PTKc_Jak_rpt2	cd05038	584	928	2.3e-38
NP_000213	PTKc_EphR_A	cd05066	584	928	1.4e-26
NP_000213	PTKc_Jak1_rpt2	cd05079	584	928	1.4e-19
NP_000213	PTKc_Tyk2_rpt2	cd05080	584	929	9.6e-13
NP_000213	PTKc_Tie2	cd05088	584	942	2.4e-46
NP_000213	PTKc_HER2	cd05109	584	938	2.6e-15
NP_000213	PTKc_Btk_Bmx	cd05113	584	925	2.6e-36
NP_000213	PTKc_Tec_Rlk	cd05114	584	925	4.2e-29
NP_000213	STKc_myosinIII_like	cd06608	585	924	1.6e-08
NP_000213	STKc_PDK1	cd05581	587	923	7.5e-10
NP_000213	PKc_MAPKK	cd06605	587	930	6.9e-07
NP_000213	PKc_MKK3_6	cd06617	587	945	0.00024
NP_000213	STKc_CDKL	cd07833	587	923	0.00051
NP_000213	PTKc_RET	cd05045	588	931	9.7e-87
NP_000213	PKc_STE	cd05122	588	919	1.9e-09
NP_000213	STKc_MAPKKK	cd06606	588	929	1.5e-13
NP_000213	STKc_Cdc7_like	cd06627	588	920	3.4e-08
NP_000213	STKc_MPK1	cd07857	588	939	0.00047
NP_000213	PTKc_Axl_like	cd05035	589	928	3.5e-36
NP_000213	PTKc_Tyro3	cd05074	589	928	6.7e-29
NP_000213	PTKc_Tec_like	cd05059	589	925	6.7e-23
NP_000213	PTKc_Axl	cd05075	589	928	9.7e-31
NP_000213	STKc_CDK_like	cd07829	589	923	1.2e-08
NP_000213	STKc_MAK_like	cd07830	591	926	0.00035
NP_000213	STKc_YSK4	cd06631	592	923	5.8e-06
NP_000213	PTKc	cd00192	593	925	1.7e-132
NP_000213	PTKc_Ack_like	cd05040	593	925	5.2e-23
NP_000213	PTKc_Aatyk	cd05042	593	926	4e-11
NP_000213	PTKc_c-ros	cd05044	593	926	8.2e-34
NP_000213	PTKc_Tie	cd05047	593	929	1.8e-53
NP_000213	PTKc_Syk_like	cd05060	593	929	1.6e-24
NP_000213	PTKc_Fes_like	cd05041	593	926	1.1e-37
NP_000213	PTKc_Fes	cd05084	593	926	1.1e-33
NP_000213	PTKc_Aatyk2	cd05086	593	926	4e-06
NP_000213	PTKc_Aatyk1_Aatyk3	cd05087	593	926	2.1e-11
NP_000213	PTKc_Fer	cd05085	593	926	4e-41
NP_000213	STKc_Nek	cd08215	593	926	1.7e-08
NP_000213	STKc_Nek2	cd08217	593	926	1.9e-05
NP_000213	PTKc_Zap-70	cd05115	594	929	3.9e-22
NP_000213	PKc	cd00180	595	924	8.2e-41
NP_000213	STKc_AGC	cd05123	595	922	6.9e-07
NP_000213	STKc_PAK1	cd06654	633	945	0.00042
NP_000213	PKc_MAPKK_PBS2_like	cd06622	639	964	0.00012
NP_000213	PTKc_HER4	cd05110	641	955	2.5e-09
NP_000213	PTKc_Jak2_Jak3_rpt2	cd05081	646	928	4.7e-24
NP_000213	PTK_HER3	cd05111	646	938	4e-16
NP_000213	STKc_myosinIIIB	cd06639	646	925	0.00029
NP_000213	STKc_PAK6	cd06659	647	961	0.00085
NP_000213	PTKc_Itk	cd05112	648	925	2.6e-24
NP_000213	STKc_MEKK2	cd06652	648	919	0.00076
NP_000213	STKc_GRK4_like	cd05605	650	975	0.00065
NP_000213	STKc_MAPKKK_Byr2_lik	cd06628	650	926	6e-06
NP_000213	STKc_Nek3	cd08219	650	926	1.2e-05
NP_000213	STKc_Nek4	cd08223	650	924	3.4e-05
NP_000213	STKc_GRK1	cd05608	657	945	0.00076
NP_000213	STKc_CDK12	cd07864	658	923	0.00013
NP_000213	PTKc_EphR_B	cd05065	662	928	3e-21
NP_000213	STKc_MST4	cd06640	664	948	0.00043
NP_000213	STKc_STK25-YSK1	cd06642	664	949	4e-05
NP_000213	STKc_Nek5	cd08225	665	923	0.00022
NP_000213	STKc_CDKL1_4	cd07847	666	956	0.00048
NP_000213	PTKc_Met_Ron	cd05058	668	930	1.2e-40
NP_000213	STKc_TAO2	cd06634	669	954	0.00061
NP_000213	PTK_Jak1_rpt1	cd05077	671	925	2e-05
NP_000213	PTK_Jak2_Jak3_rpt1	cd05078	671	925	6.9e-07
NP_000213	PTKc_Syk	cd05116	676	929	6e-29
NP_000213	PKc_MKK7	cd06618	676	938	0.00039
NP_000213	STKc_Nek6	cd08228	678	930	0.00063
NP_000213	STKc_Nek7	cd08229	678	929	1.8e-05
NP_000213	STKc_Nek6_Nek7	cd08224	678	930	0.00035
NP_000213	STKc_MEKK3_like	cd06625	679	926	0.00021
NP_000213	STKc_STK10_LOK	cd06644	679	947	0.00028
NP_000213	PTK_Ryk	cd05043	682	928	8.5e-19
NP_000213	STKc_SLK	cd06643	684	944	0.00044
NP_000213	STKc_CMGC	cd05118	689	923	4.7e-07
NP_000213	PKc_MKK4	cd06616	689	939	0.0003
NP_000213	STKc_MST1_2	cd06612	691	920	1.1e-06
NP_000213	STKc_CdkB_plant	cd07837	693	952	0.00025
NP_000213	STKc_PAK_II	cd06648	695	939	8e-05
NP_000213	STKc_Nek9	cd08221	699	925	0.00019
NP_000213	STKc_PAK	cd06614	703	939	8e-09
NP_000213	STKc_CDK9_like	cd07840	703	917	2.2e-05
NP_000213	PTK_Jak_rpt1	cd05037	712	925	4.2e-05
NP_000213	STKc_MEKK1	cd06630	712	925	0.00075
NP_000213	STKc_CDK10	cd07845	712	928	0.00089
NP_000213	STKc_BUR1	cd07866	714	917	0.00035
NP_000213	STKc_MAST_like	cd05579	716	930	0.00015
NP_000213	STKc_MAP4K3_like	cd06613	717	925	7.6e-06
NP_000213	STKc_OSR1_SPAK	cd06610	719	917	3.1e-05
NP_000213	PKc_MAPKK_plant_like	cd06623	720	926	6.1e-06
NP_000213	STKc_MAPK	cd07834	720	953	8.4e-05
NP_000213	STKc_CDKL2_3	cd07846	720	922	0.00037
NP_000213	STKc_FA2-like	cd08529	720	924	3.9e-05
NP_000213	STKc_MEKK1_plant	cd06632	721	921	5.7e-05
NP_000213	PKc_MAPKK_Byr1_like	cd06620	723	940	0.00045
NP_000213	STKc_CNK2-like	cd08530	727	924	2.1e-05
NP_000213	STKc_CDK7	cd07841	729	921	4.4e-05
NP_000213	STKc_Yank1	cd05578	730	937	2.3e-05
NP_000213	STKc_SLK_like	cd06611	731	941	1e-05
NP_000213	STKc_MAPK15	cd07852	735	939	2e-05
NP_000213	STKc_MST3_like	cd06609	736	931	3.8e-05
NP_000213	STKc_MEKK4	cd06626	738	920	2.5e-05
NP_000213	STKc_NAK1_like	cd06917	739	936	1.5e-05
NP_000213	PKc_MAPKK_Pek1_like	cd06621	740	943	0.00014
NP_000213	STKc_MAPKKK_Bck1_lik	cd06629	742	918	5.9e-08
NP_000213	ig	pfam00047	226	292	6.1e-14
NP_000213	Pkinase	pfam00069	589	924	3.9e-23
NP_000213	I-set	pfam07679	212	307	6.1e-05
NP_000213	IG	smart00409	218	308	1.9e-14
NP_000213	IG_like	smart00410	218	308	1.9e-14
NP_000213	Pkinase_Tyr	pfam07714	589	924	4.4e-172
NP_000213	TyrKc	smart00219	589	924	5e-172
NP_000213	STYKc	smart00221	589	897	1.4e-63
NP_000213	S_TKc	smart00220	599	928	9e-27
NP_000213	KIND	smart00750	764	934	0.00028

Please Cite: Peterson, T.A., Adadey, A., Santana-Cruz ,I., Sun, Y., Winder A, Kann, M.G., (2010) DMDM: Domain Mapping of Disease Mutations. Bioinformatics 26 (19), 2458-2459.

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