Results for the gene: MLH1

Results for Proteins associated with the Gene: MLH1

MLH1

4292

P40692 NP_000240 NP_001161091 NP_001161090 NP_001161089 NP_001245203 NP_001245202 NP_001245200

NCBI

Known Diseases associated with this Protein:

COLORECTAL CANCER, HEREDITARY NONPOLYPOSIS, TYPE 2

COLORECTAL CANCER, HEREDITARY NONPOLYPOSIS, TYPE 2, INCLUDED

COLORECTAL CANCER, SPORADIC, SUSCEPTIBILITY TO

HEREDITARY NON-POLYPOSIS COLORECTAL CANCER 2 (HNPCC2)

MISMATCH REPAIR CANCER SYNDROME

MISMATCH REPAIR CANCER SYNDROME (MMRCS)

MISMATCH REPAIR CANCER SYNDROME, INCLUDED

RECLASSIFIED - VARIANT OF UNKNOWN SIGNIFICANCE

			132 80 65 8 139

Tips:

The Domains on the Default View are decided by HMMER's search E-Value of the Protein against the Domain model.

Clicking a check box on the left will display or hide the corresponding domain(s).

To view the Protein page, either click on the protein links in the box to the left or the blue bar above the Protein's graphic.

Default View:	Swiss-Prot Protein: P40692 Identical to: NP_000240 Default View:

Default View: MutL - COG0323 HATPase_c - cd00075 MutL_Trans_MLH3 - cd03486 MutL_Trans_hPMS_1_li - cd03485 MutL_Trans_hPMS_2_li - cd03484 MutL_Trans_MLH1 - cd03483 MutL_Trans - cd00782 TopoII_MutL_Trans - cd00329 DNA_mis_repair - pfam01119 MutL_Trans_MutL - cd03482	RefSeq Protein: NP_000240 Default View:

Default View: DNA_mis_repair - pfam01119 TopoII_MutL_Trans - cd00329 MutL_Trans_MLH1 - cd03483 MutL_Trans - cd00782 MutL_Trans_MutL - cd03482 MutL_Trans_hPMS_2_li - cd03484	RefSeq Protein: NP_001161091 Default View:

Default View: DNA_mis_repair - pfam01119 TopoII_MutL_Trans - cd00329 MutL_Trans_MLH1 - cd03483 MutL_Trans - cd00782 MutL_Trans_MutL - cd03482 MutL_Trans_hPMS_2_li - cd03484	RefSeq Protein: NP_001161090 Default View:

Default View: MutL - COG0323 MutL_Trans_MLH3 - cd03486 MutL_Trans_hPMS_2_li - cd03484 MutL_Trans_hPMS_1_li - cd03485 MutL_Trans_MLH1 - cd03483 MutL_Trans - cd00782 TopoII_MutL_Trans - cd00329 DNA_mis_repair - pfam01119 MutL_Trans_MutL - cd03482	RefSeq Protein: NP_001161089 Default View:

Default View: DNA_mis_repair - pfam01119 TopoII_MutL_Trans - cd00329 MutL_Trans_MLH1 - cd03483 MutL_Trans - cd00782 MutL_Trans_MutL - cd03482 MutL_Trans_hPMS_2_li - cd03484	RefSeq Protein: NP_001245203 Default View:

Default View: DNA_mis_repair - pfam01119 TopoII_MutL_Trans - cd00329 MutL_Trans_MLH1 - cd03483 MutL_Trans - cd00782 MutL_Trans_MutL - cd03482 MutL_Trans_hPMS_2_li - cd03484	RefSeq Protein: NP_001245202 Default View:

Default View: MutL - COG0323 HATPase_c - cd00075 MutL_Trans_MLH3 - cd03486 MutL_Trans_hPMS_1_li - cd03485 MutL_Trans_hPMS_2_li - cd03484 MutL_Trans_MLH1 - cd03483 MutL_Trans - cd00782 TopoII_MutL_Trans - cd00329 DNA_mis_repair - pfam01119 MutL_Trans_MutL - cd03482	RefSeq Protein: NP_001245200 Default View:

Domains found on the Proteins

Protein ↕	Domain ↕	Domain Accession ↕	Start ↕	End ↕	E-Value ↕
NP_001245200	HATPase_c	cd00075	28	154	2.7e-18
NP_001245200	MutL_Trans_MLH1	cd03483	211	335	6.4e-90
NP_001245200	MutL_Trans_hPMS_2_li	cd03484	211	335	2.7e-10
NP_001245200	MutL_Trans_hPMS_1_li	cd03485	211	335	3.4e-06
NP_001245200	MutL_Trans_MLH3	cd03486	211	335	0.0004
NP_001245200	TopoII_MutL_Trans	cd00329	212	315	6.7e-29
NP_001245200	MutL_Trans	cd00782	212	334	9.5e-49
NP_001245200	MutL_Trans_MutL	cd03482	216	335	5.9e-07
NP_001245200	DNA_mis_repair	pfam01119	216	334	1.9e-47

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