Results for the gene: PDGFRA

Results for Proteins associated with the Gene: PDGFRA

PDGFRA

5156

P16234 NP_006197

NCBI

Known Diseases associated with this Protein:

GASTROINTESTINAL STROMAL TUMOR (GIST)

GASTROINTESTINAL STROMAL TUMOR, FAMILIAL

GASTROINTESTINAL STROMAL TUMOR, FAMILIAL, INCLUDED

GASTROINTESTINAL STROMAL TUMOR, SOMATIC

HYPEREOSINOPHILIC SYNDROME, IDIOPATHIC, RESISTANT TO IMATINIB

VARIANT OF UNKNOWN SIGNIFICANCE

			9 21 8 2 20

Tips:

The Domains on the Default View are decided by HMMER's search E-Value of the Protein against the Domain model.

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Swiss-Prot Protein: P16234

Identical to: NP_006197

Default View:

RefSeq Protein: NP_006197

Default View:

Domains found on the Proteins

Protein ↕	Domain ↕	Domain Accession ↕	Start ↕	End ↕	E-Value ↕
NP_006197	Ig1_PDGFR-alphabeta	cd05861	228	311	4.8e-58
NP_006197	Ig1_VEGFR	cd05862	228	311	0.00012
NP_006197	Ig4_SCFR_like	cd04975	313	413	3e-57
NP_006197	Ig4_PDGFR-alpha	cd05859	313	413	1.6e-74
NP_006197	Ig4_SCFR	cd05860	313	415	2.5e-06
NP_006197	Ig2_VEGFR	cd04976	333	411	0.00096
NP_006197	Ig	cd00096	335	408	5.7e-06
NP_006197	Ig_TrkABC_d4	cd04972	415	497	3.2e-33
NP_006197	PTKc_CSF-1R	cd05106	552	955	1.2e-174
NP_006197	PTKc_PDGFR	cd05055	555	954
NP_006197	PTKc_Kit	cd05104	555	954	9.8e-180
NP_006197	PTKc_PDGFR_alpha	cd05105	555	956
NP_006197	PTKc_PDGFR_beta	cd05107	555	955	1e-241
NP_006197	PTKc_FGFR1	cd05098	575	961	2.7e-83
NP_006197	PTKc_FGFR2	cd05101	577	961	1.1e-79
NP_006197	PTKc_EGFR_like	cd05057	578	962	3.5e-29
NP_006197	PTKc_FGFR	cd05053	580	955	3.2e-111
NP_006197	PTKc_FGFR4	cd05099	580	975	1.5e-81
NP_006197	PTKc_FGFR3	cd05100	580	989	5.8e-70
NP_006197	PTKc_VEGFR	cd05054	585	957	2e-150
NP_006197	PTKc_VEGFR2	cd05103	585	957	2.1e-125
NP_006197	PTKc_VEGFR3	cd05102	585	957	6.7e-136
NP_006197	PTKc_ALK_LTK	cd05036	586	952	2.5e-41
NP_006197	PTKc_Csk_like	cd05039	586	953	3.7e-35
NP_006197	PTKc_InsR_like	cd05032	586	955	2.1e-48
NP_006197	PTKc_Src_like	cd05034	586	953	1.7e-51
NP_006197	PTKc_Abl	cd05052	586	954	1.9e-42
NP_006197	PTKc_FAK	cd05056	586	958	1.9e-39
NP_006197	PTKc_InsR	cd05061	586	962	1.4e-30
NP_006197	PTKc_IGF-1R	cd05062	586	952	4e-30
NP_006197	PTKc_Frk_like	cd05068	586	953	3.5e-47
NP_006197	PTKc_Yes	cd05069	586	953	7e-27
NP_006197	PTKc_Src	cd05071	586	955	1.7e-27
NP_006197	PTKc_Lyn	cd05072	586	953	6.2e-34
NP_006197	PTKc_Lck_Blk	cd05067	586	953	6.4e-34
NP_006197	PTKc_Hck	cd05073	586	953	2.1e-36
NP_006197	PTKc_Csk	cd05082	586	953	4.1e-35
NP_006197	PTKc_Chk	cd05083	586	953	2.8e-41
NP_006197	PTKc_Tie1	cd05089	586	978	1.8e-42
NP_006197	PTKc_Fyn_Yrk	cd05070	586	953	6.7e-30
NP_006197	PTKc_Srm_Brk	cd05148	586	953	1.8e-37
NP_006197	PTK_CCK4	cd05046	587	952	8e-17
NP_006197	PTKc_Ror	cd05048	587	953	1.2e-32
NP_006197	PTKc_Trk	cd05049	587	955	8.3e-40
NP_006197	PTKc_Musk	cd05050	587	952	7.9e-53
NP_006197	PTKc_EphR_A10	cd05064	587	954	1.7e-09
NP_006197	PTKc_Ror1	cd05090	587	953	3.1e-18
NP_006197	PTKc_Ror2	cd05091	587	953	8.1e-21
NP_006197	PTKc_TrkA	cd05092	587	956	6.5e-32
NP_006197	PTKc_TrkB	cd05093	587	968	9.8e-25
NP_006197	PTKc_TrkC	cd05094	587	964	2e-12
NP_006197	PTKc_DDR2	cd05095	587	952	4.5e-24
NP_006197	PTKc_DDR1	cd05096	587	952	9e-27
NP_006197	PTKc_DDR_like	cd05097	587	952	3.2e-26
NP_006197	PTKc_DDR	cd05051	587	952	9e-18
NP_006197	PTKc_EphR	cd05033	588	954	1.3e-21
NP_006197	PTKc_Jak_rpt2	cd05038	588	954	3.2e-31
NP_006197	PTKc_EphR_B	cd05065	588	954	5.8e-17
NP_006197	PTKc_EphR_A	cd05066	588	954	6e-19
NP_006197	PTKc_Tie2	cd05088	588	979	4.2e-38
NP_006197	PTKc_Btk_Bmx	cd05113	588	951	4.9e-37
NP_006197	PTKc_Tec_Rlk	cd05114	588	951	2.4e-29
NP_006197	STKc_myosinIII_like	cd06608	589	949	2.4e-05
NP_006197	STKc_PDK1	cd05581	591	944	4.2e-07
NP_006197	SPS1	COG0515	591	1089	6e-10
NP_006197	PTKc_RET	cd05045	592	957	6.8e-83
NP_006197	STKc_MAPKKK	cd06606	592	944	3.9e-13
NP_006197	STKc_Cdc7_like	cd06627	592	943	1.8e-08
NP_006197	STKc_Nek	cd08215	592	950	3.9e-08
NP_006197	PTKc_Axl_like	cd05035	593	954	6.2e-41
NP_006197	PTKc_Tec_like	cd05059	593	951	3.6e-28
NP_006197	PTKc_Tyro3	cd05074	593	954	7e-39
NP_006197	PTKc_Axl	cd05075	593	954	5.7e-34
NP_006197	PTKc	cd00192	597	954	1.4e-135
NP_006197	PTKc_Fes_like	cd05041	597	952	6.8e-36
NP_006197	PTKc_c-ros	cd05044	597	952	2.4e-37
NP_006197	PTKc_Tie	cd05047	597	955	1.6e-48
NP_006197	PTKc_Syk_like	cd05060	597	955	8e-26
NP_006197	PTKc_Fer	cd05085	597	955	2e-37
NP_006197	PTKc_Aatyk2	cd05086	597	952	0.00013
NP_006197	PTKc_Aatyk1_Aatyk3	cd05087	597	952	1.3e-06
NP_006197	PKc	cd00180	599	953	1.6e-34
NP_006197	PTKc_Aatyk	cd05042	599	956	4.1e-10
NP_006197	STKc_AGC	cd05123	599	944	4.1e-07
NP_006197	STKc_Nek11	cd08222	671	955	0.0002
NP_006197	STKc_Nek10	cd08528	675	952	0.00083
NP_006197	PTKc_Met_Ron	cd05058	684	956	3.7e-39
NP_006197	PTKc_Jak1_rpt2	cd05079	684	954	9.3e-19
NP_006197	STKc_PAK_II	cd06648	690	954	0.00039
NP_006197	PTK_HER3	cd05111	691	966	1.8e-14
NP_006197	PTKc_EGFR	cd05108	694	996	2.9e-14
NP_006197	PTKc_HER2	cd05109	694	966	2.8e-16
NP_006197	PTKc_HER4	cd05110	694	998	1.3e-10
NP_006197	STKc_Nek6	cd08228	694	955	0.00044
NP_006197	PTKc_Jak2_Jak3_rpt2	cd05081	697	954	1.3e-14
NP_006197	PTKc_Itk	cd05112	697	951	2e-29
NP_006197	STKc_MST4	cd06640	697	974	0.00065
NP_006197	STKc_CdkB_plant	cd07837	699	945	0.00032
NP_006197	STKc_CDK4	cd07863	700	977	0.00056
NP_006197	STKc_Nek7	cd08229	702	955	1.8e-06
NP_006197	STKc_nPKC_theta	cd05619	703	1021	4.5e-05
NP_006197	STKc_PCTAIRE_like	cd07844	703	993	0.00038
NP_006197	PKc_MAPKK_PBS2_like	cd06622	706	1010	0.00012
NP_006197	STKc_Pho85	cd07836	706	993	0.00026
NP_006197	STKc_CDKL1_4	cd07847	706	993	0.00012
NP_006197	STKc_MAPKKK_Byr2_lik	cd06628	707	954	6.3e-06
NP_006197	PTKc_EphR_A2	cd05063	709	954	1e-20
NP_006197	PKc_MKK7	cd06618	709	964	0.0004
NP_006197	STKc_SLK_like	cd06611	710	964	6.6e-05
NP_006197	STKc_CDK5	cd07839	710	993	0.00029
NP_006197	PTK_Jak1_rpt1	cd05077	711	950	2.5e-05
NP_006197	STKc_CDK12	cd07864	713	950	0.00041
NP_006197	PTK_Jak_rpt1	cd05037	715	950	4.3e-06
NP_006197	STKc_Nek8	cd08220	715	950	0.00092
NP_006197	PTK_Ryk	cd05043	716	953	3.9e-19
NP_006197	STKc_MAP4K3_like	cd06613	716	950	9.8e-05
NP_006197	STKc_Nek6_Nek7	cd08224	717	955	8.7e-05
NP_006197	STKc_OSR1_SPAK	cd06610	718	944	1.4e-05
NP_006197	STKc_MEKK3_like	cd06625	718	952	0.0009
NP_006197	STKc_CDKL2_3	cd07846	718	950	1.5e-05
NP_006197	STKc_MPK1	cd07857	719	981	0.0001
NP_006197	STKc_Nek3	cd08219	719	954	9.9e-06
NP_006197	STKc_Nek4	cd08223	719	949	0.00042
NP_006197	STKc_Nek2	cd08217	719	950	1.3e-05
NP_006197	STKc_CNK2-like	cd08530	719	950	5.4e-05
NP_006197	STKc_FA2-like	cd08529	719	949	8.1e-05
NP_006197	STKc_CMGC	cd05118	720	959	1.6e-07
NP_006197	STKc_PKN	cd05589	720	1019	9.4e-05
NP_006197	STKc_MOK	cd07831	720	943	7.4e-05
NP_006197	PTKc_Zap-70	cd05115	721	955	4.6e-23
NP_006197	PTKc_Syk	cd05116	721	959	3.2e-25
NP_006197	STKc_nPKC_theta_delt	cd05592	721	1021	7e-05
NP_006197	STKc_MEKK1_plant	cd06632	721	949	9e-06
NP_006197	PTKc_Fes	cd05084	723	955	3.8e-28
NP_006197	STKc_YPK1_like	cd05585	723	1018	0.00087
NP_006197	PTK_Jak2_Jak3_rpt1	cd05078	726	951	7.1e-05
NP_006197	STKc_MAPKKK_Bck1_lik	cd06629	727	944	5.4e-06
NP_006197	STKc_MEKK1	cd06630	727	946	0.00054
NP_006197	STKc_CDKL	cd07833	727	943	0.00099
NP_006197	PTKc_Ack_like	cd05040	728	955	2.5e-21
NP_006197	STKc_MAPK	cd07834	730	985	0.00038
NP_006197	PTKc_Tyk2_rpt2	cd05080	731	955	1.1e-10
NP_006197	STKc_CDK_like	cd07829	731	943	1.5e-07
NP_006197	STKc_YSK4	cd06631	735	954	1.2e-05
NP_006197	STKc_CDK7	cd07841	741	955	7.1e-05
NP_006197	STKc_Nek9	cd08221	741	955	6.4e-05
NP_006197	STKc_NAK1_like	cd06917	744	981	3e-06
NP_006197	PKc_STE	cd05122	745	948	3.1e-08
NP_006197	STKc_PAK	cd06614	746	961	3.9e-07
NP_006197	STKc_MAPK15	cd07852	749	998	7.4e-05
NP_006197	PKc_MKK4	cd06616	753	977	0.001
NP_006197	PKc_MAPKK_plant_like	cd06623	755	964	1.2e-05
NP_006197	STKc_MEKK4	cd06626	758	944	8.3e-05
NP_006197	STKc_CDC2L1	cd07843	759	943	0.00025
NP_006197	STKc_MST3_like	cd06609	760	962	5.4e-05
NP_006197	STKc_MST1_2	cd06612	766	944	3.3e-05
NP_006197	STKc_Yank1	cd05578	767	953	8.1e-05
NP_006197	STKc_CDK9_like	cd07840	768	943	9.4e-06
NP_006197	STKc_MAST_like	cd05579	769	943	0.00036
NP_006197	STKc_PKC	cd05570	771	994	0.00019
NP_006197	Pkinase	pfam00069	593	950	2.7e-14
NP_006197	IG	smart00409	220	310	2.4e-07
NP_006197	IG_like	smart00410	220	310	2.4e-07
NP_006197	IGc2	smart00408	227	297	0.001
NP_006197	I-set	pfam07679	319	413	8.9e-06
NP_006197	IG	smart00409	322	412	1.1e-05
NP_006197	IG_like	smart00410	322	412	1.1e-05
NP_006197	Pkinase_Tyr	pfam07714	593	953	1.7e-189
NP_006197	TyrKc	smart00219	593	950	1.1e-132
NP_006197	STYKc	smart00221	593	923	7.4e-43
NP_006197	S_TKc	smart00220	603	954	4.1e-24

Please Cite: Peterson, T.A., Adadey, A., Santana-Cruz ,I., Sun, Y., Winder A, Kann, M.G., (2010) DMDM: Domain Mapping of Disease Mutations. Bioinformatics 26 (19), 2458-2459.

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