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Results for Proteins associated with the Gene: PIK3CA
PIK3CA
5290


Known Diseases associated with this Protein:
  BREAST CANCER, SOMATIC
  COLORECTAL CANCER, SOMATIC
  COLORECTAL CANCER, SOMATIC, INCLUDED
  COLORECTAL CANCER, SOMATIC, INCLUDED;;
  CONGENITAL LIPOMATOUS OVERGROWTH, VASCULAR MALFORMATIONS, AND EPIDERMAL
  CONGENITAL LIPOMATOUS OVERGROWTH, VASCULAR MALFORMATIONS, AND EPIDERMAL NEVI (CLOVE)
  COWDEN DISEASE 5
  GASTRIC
  HEPATOCELLULAR CARCINOMA, SOMATIC
  KERATOSIS, SEBORRHEIC (KERSEB)
  MEGALENCEPHALY-CAPILLARY MALFORMATION-POLYMICROGYRIA SYNDROME (MCAP)
  MEGALENCEPHALY-CAPILLARY MALFORMATION-POLYMICROGYRIA SYNDROME, SOMATIC
  NEVI, SOMATIC
  NEVI, SOMATIC, INCLUDED
  NEVUS, EPIDERMAL, SOMATIC, INCLUDED
  OVARIAN CANCER, EPITHELIAL, SOMATIC
  OVARIAN CANCER, EPITHELIAL, SOMATIC, INCLUDED;;
36
29
18
1
46
Tips:
 The Domains on the Default View are decided by HMMER's search E-Value of the Protein against the Domain model.
 Clicking a check box on the left will display or hide the corresponding domain(s).
 To view the Protein page, either click on the protein links in the box to the left or the blue bar above the Protein's graphic.


Default View:

PI3K_p85B - pfam02192
PI3K_p85B - smart00143
PI3K_rbd - pfam00794
PI3K_rbd - smart00144
PI3K_C2 - smart00142
C2_PI3K_class_I_gamm - cd08399
C2_PI3K_class_III - cd08397
C2_PI3K_like - cd08380
C2A_PI3K_class_II - cd04012
C2_PI3K_class_I_beta - cd08693
C2_PI3K_class_I_alph - cd08398
PI3K_C2 - pfam00792
PI3Ka - pfam00613
PI3Ka_III - cd00870
PI3Ka - smart00145
PI3Ka_II - cd00869
PI3Ka - cd00864
PI3Ka_I - cd00872
PI3Kc_I - cd05165
PI3Kc_III - cd00896
PI3Kc_IB_gamma - cd00894
PI3Kc - cd00891
PI3Kc_II - cd05166
PI3Kc_IA_beta - cd05173
PI3Kc_IA_alpha - cd05175
PI3Kc_IA_delta - cd05174
PI3Kc_C2_beta - cd00895
PI3Kc_C2_alpha - cd05176
PI3Kc_C2_gamma - cd05177
PI4Kc_III_alpha - cd05167
PI3Kc_like - cd00142
PI4Kc_III - cd00893
PIKKc_ATR - cd00892
PIKKc - cd05164
PIKKc_DNA-PK - cd05172
PIKKc_ATM - cd05171
PI4Kc_III_beta - cd05168
PIKKc_TOR - cd05169
PI3_PI4_kinase - pfam00454
PI3Kc - smart00146


Swiss-Prot Protein: P42336
Identical to: NP_006209
   Default View:























Default View:

PI3K_p85B - pfam02192
PI3K_p85B - smart00143
PI3K_rbd - pfam00794
PI3K_rbd - smart00144
PI3K_C2 - smart00142
C2_PI3K_class_I_gamm - cd08399
C2_PI3K_class_III - cd08397
C2_PI3K_like - cd08380
C2A_PI3K_class_II - cd04012
C2_PI3K_class_I_beta - cd08693
C2_PI3K_class_I_alph - cd08398
PI3K_C2 - pfam00792
PI3Ka - pfam00613
PI3Ka_III - cd00870
PI3Ka - smart00145
PI3Ka_I - cd00872
PI3Ka - cd00864
PI3Ka_II - cd00869
PI3Kc_I - cd05165
PI3Kc_III - cd00896
PI3Kc_IB_gamma - cd00894
PI3Kc - cd00891
PI3Kc_II - cd05166
PI3Kc_IA_beta - cd05173
PI3Kc_IA_alpha - cd05175
PI3Kc_IA_delta - cd05174
PI3Kc_C2_beta - cd00895
PI3Kc_C2_alpha - cd05176
PI3Kc_C2_gamma - cd05177
PI4Kc_III_alpha - cd05167
PI3Kc_like - cd00142
PI4Kc_III - cd00893
PIKKc_ATR - cd00892
PIKKc - cd05164
PIKKc_DNA-PK - cd05172
PIKKc_ATM - cd05171
PI4Kc_III_beta - cd05168
PIKKc_TOR - cd05169
PI3_PI4_kinase - pfam00454
PI3Kc - smart00146


RefSeq Protein: NP_006209
   Default View:
























Domains found on the Proteins

Protein ↕Domain ↕Domain Accession ↕Start ↕End ↕E-Value ↕
NP_006209C2_PI3K_class_I_gammcd083993234846.9e-08
NP_006209C2A_PI3K_class_IIcd040123254875e-07
NP_006209C2_PI3K_likecd083803254847.2e-66
NP_006209C2_PI3K_class_I_alphcd083983254842.4e-135
NP_006209C2_PI3K_class_I_betacd086933254836.5e-42
NP_006209PI3Ka_IIIcd008705206772.6e-15
NP_006209PI3Kacd008645256774e-82
NP_006209PI3Ka_Icd008725256961.4e-132
NP_006209PI3Ka_IIcd008695256924.5e-37
NP_006209PI3Kccd0089169910646.1e-224
NP_006209PI3Kc_IB_gammacd0089469910646.5e-117
NP_006209PI3Kc_IIIcd0089669910512.6e-20
NP_006209PI3Kc_Icd0516569910641.6e-287
NP_006209PI3Kc_IIcd0516669910642.7e-96
NP_006209PI3Kc_IA_betacd0517369910655.5e-134
NP_006209PI3Kc_IA_deltacd0517469910644.3e-130
NP_006209PI3Kc_IA_alphacd051756991064
NP_006209PI3Kc_C2_betacd0089570010645.1e-77
NP_006209PI3Kc_C2_alphacd0517670310644.1e-77
NP_006209PI3Kc_C2_gammacd0517770310643.4e-70
NP_006209PI4Kc_III_alphacd0516775410592.8e-23
NP_006209PI3Kc_likecd0014276210081.2e-109
NP_006209PI4Kc_IIIcd0089376210678.2e-32
NP_006209PIKKc_ATRcd008927669793e-06
NP_006209PIKKccd0516476710087.6e-08
NP_006209PIKKc_DNA-PKcd051727679930.00022
NP_006209PIKKc_ATMcd0517178010042.2e-08
NP_006209PI4Kc_III_betacd0516878710551.8e-15
NP_006209PIKKc_TORcd0516979410062.3e-05
NP_006209PI3K_p85Bpfam02192311082.5e-43
NP_006209PI3K_rbdpfam007941732923.3e-56
NP_006209PI3K_C2pfam007923504856.9e-45
NP_006209PI3Kapfam006135197041.5e-110
NP_006209PI3_PI4_kinasepfam0045479610151.5e-95
NP_006209PI3K_p85Bsmart00143311083.8e-49
NP_006209PI3K_rbdsmart001441732929.9e-56
NP_006209PI3K_C2smart001423224181.7e-35
NP_006209PI3Kasmart001455217049.9e-100
NP_006209PI3Kcsmart0014679810222.7e-115



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