Results for the gene: TGFBR2

Results for Proteins associated with the Gene: TGFBR2

TGFBR2

7048

P37173 NP_001020018 NP_003233

NCBI

Known Diseases associated with this Protein:

COLON CANCER, HEREDITARY NONPOLYPOSIS, TYPE 6, SOMATIC, INCLUDED

COLORECTAL CANCER, HEREDITARY NONPOLYPOSIS, TYPE 6

ESOPHAGEAL CANCER (ESCR)

ESOPHAGEAL CANCER, SOMATIC

HEREDITARY NON-POLYPOSIS COLORECTAL CANCER 6 (HNPCC6)

LOEYS-DIETZ SYNDROME 1B (LDS1B)

LOEYS-DIETZ SYNDROME 2B (LDS2B)

LOEYS-DIETZ SYNDROME, TYPE 1B

LOEYS-DIETZ SYNDROME, TYPE 1B, INCLUDED

LOEYS-DIETZ SYNDROME, TYPE 2B

			52 12 32 0 32

Tips:

The Domains on the Default View are decided by HMMER's search E-Value of the Protein against the Domain model.

Clicking a check box on the left will display or hide the corresponding domain(s).

To view the Protein page, either click on the protein links in the box to the left or the blue bar above the Protein's graphic.

Swiss-Prot Protein: P37173

Identical to: NP_003233

Default View:

RefSeq Protein: NP_001020018

Default View:

RefSeq Protein: NP_003233

Default View:

Domains found on the Proteins

Protein ↕	Domain ↕	Domain Accession ↕	Start ↕	End ↕	E-Value ↕
NP_003233	STKc_myosinIIIB	cd06639	224	511	0.00033
NP_003233	STKc_PAK	cd06614	227	542	2.9e-07
NP_003233	PTKc_FGFR2	cd05101	228	555	0.00018
NP_003233	STKc_MAP4K4_6	cd06636	230	510	0.00033
NP_003233	STKc_p38	cd07851	230	562	0.00026
NP_003233	PTKc_FGFR	cd05053	231	548	4.2e-06
NP_003233	PTKc_EGFR_like	cd05057	233	555	0.00012
NP_003233	PTK_HER3	cd05111	233	550	0.00073
NP_003233	PKc_MKK7	cd06618	233	544	0.00029
NP_003233	PTKc_HER2	cd05109	234	555	7.8e-05
NP_003233	STKc_MAP4K3	cd06645	234	535	0.00039
NP_003233	STKc_MAP4K5	cd06646	234	509	0.001
NP_003233	PTK_CCK4	cd05046	235	540	0.0005
NP_003233	STKc_ASK	cd06624	235	539	0.00041
NP_003233	STKc_STK10_LOK	cd06644	235	555	0.00024
NP_003233	PTKc_Abl	cd05052	237	542	7.5e-05
NP_003233	PTKc_FAK	cd05056	237	546	6.8e-06
NP_003233	PTKc_Frk_like	cd05068	237	541	8.8e-06
NP_003233	PTKc_Fyn_Yrk	cd05070	237	538	0.00043
NP_003233	PTKc_Hck	cd05073	237	538	0.00012
NP_003233	PTKc_Csk	cd05082	237	541	5.1e-05
NP_003233	PTKc_Chk	cd05083	237	541	0.00015
NP_003233	PTKc_FGFR1	cd05098	237	555	0.00013
NP_003233	STKc_PCTAIRE_like	cd07844	237	558	0.00091
NP_003233	STKc_CDK12	cd07864	237	539	7.2e-05
NP_003233	PTKc_Trk	cd05049	238	540	2e-07
NP_003233	PTKc_Ror	cd05048	238	541	1.8e-06
NP_003233	PTKc_Tie2	cd05088	238	536	0.00035
NP_003233	PTKc_EphR	cd05033	239	542	7.4e-07
NP_003233	PTKc_ALK_LTK	cd05036	239	540	1.1e-05
NP_003233	PTKc_EphR_B	cd05065	239	511	0.00011
NP_003233	PTKc_EphR_A	cd05066	239	517	0.00063
NP_003233	PKc_MKK3_6	cd06617	239	519	7.1e-06
NP_003233	PTKc_InsR_like	cd05032	240	540	1.1e-06
NP_003233	PTKc_EphR_A2	cd05063	240	542	3.2e-05
NP_003233	PTKc_Itk	cd05112	241	539	0.00034
NP_003233	PTKc_Btk_Bmx	cd05113	241	539	0.00014
NP_003233	STKc_SLK_like	cd06611	241	555	9.1e-06
NP_003233	STKc_SLK	cd06643	241	557	5.8e-05
NP_003233	STKc_Nek6_Nek7	cd08224	241	515	6.5e-05
NP_003233	STKc_Nek6	cd08228	241	514	0.00013
NP_003233	STKc_Nek7	cd08229	241	543	0.00011
NP_003233	PTKc_Jak_rpt2	cd05038	242	542	1.4e-08
NP_003233	PTK_Ryk	cd05043	242	541	2.5e-05
NP_003233	PTKc_Yes	cd05069	242	538	0.00099
NP_003233	PTKc_Src	cd05071	242	540	0.00066
NP_003233	PTKc_DDR2	cd05095	242	540	0.00077
NP_003233	PTKc_FGFR4	cd05099	242	559	1.7e-05
NP_003233	PTKc_Srm_Brk	cd05148	242	541	2.3e-08
NP_003233	STKc_myosinIII_like	cd06608	242	484	5.6e-08
NP_003233	PTKc_Ror2	cd05091	243	541	0.00047
NP_003233	STKc_MAPKKK	cd06606	243	484	4.7e-12
NP_003233	STKc_MEKK3_like	cd06625	243	510	5.5e-07
NP_003233	STKc_Cdc7_like	cd06627	243	484	1.1e-08
NP_003233	STKc_MEKK3	cd06651	243	512	1.1e-05
NP_003233	STKc_MEKK3_like_1	cd06653	243	526	0.00013
NP_003233	STKc_MAPK	cd07834	243	560	4.9e-05
NP_003233	PTKc_Src_like	cd05034	244	541	2.2e-05
NP_003233	PTKc_Axl_like	cd05035	244	542	0.00012
NP_003233	PTKc_Csk_like	cd05039	244	485	1.8e-05
NP_003233	PTKc_Musk	cd05050	244	540	2.3e-06
NP_003233	PTKc_Tyro3	cd05074	244	542	0.00071
NP_003233	PTKc_Jak1_rpt2	cd05079	244	542	0.00057
NP_003233	PTKc_Tyk2_rpt2	cd05080	244	543	7.9e-06
NP_003233	PTKc_Tie1	cd05089	244	527	0.00093
NP_003233	PKc_MAPKK	cd06605	244	515	1.1e-06
NP_003233	PKc_MAPKK_plant_like	cd06623	244	540	2.8e-06
NP_003233	STKc_TNIK	cd06637	244	510	4.5e-05
NP_003233	STKc_CDKL1_4	cd07847	244	540	0.0008
NP_003233	PKc_STE	cd05122	245	538	4.3e-10
NP_003233	STKc_PDK1	cd05581	245	504	1.9e-08
NP_003233	STKc_CRIK	cd05601	245	557	0.0005
NP_003233	STKc_OSR1_SPAK	cd06610	245	484	6.6e-06
NP_003233	STKc_MST1_2	cd06612	245	484	1.7e-05
NP_003233	STKc_MAP4K3_like	cd06613	245	538	1.7e-07
NP_003233	STKc_CDK_like	cd07829	245	539	3.9e-05
NP_003233	STKc_CdkB_plant	cd07837	245	540	0.00032
NP_003233	STKc_CDK4_6_like	cd07838	245	484	0.00019
NP_003233	STKc_CDK9_like	cd07840	245	538	0.00052
NP_003233	STKc_CDK7	cd07841	245	558	5.1e-05
NP_003233	STKc_CDKL2_3	cd07846	245	539	0.00015
NP_003233	STKc_CDKL	cd07833	245	539	0.00025
NP_003233	STKc_Nek	cd08215	245	540	7.8e-08
NP_003233	STKc_Nek2	cd08217	245	510	0.00013
NP_003233	STKc_CNK2-like	cd08530	245	541	0.00023
NP_003233	STKc_MEKK4	cd06626	247	533	2.3e-06
NP_003233	STKc_MAPKKK_Byr2_lik	cd06628	247	522	0.00034
NP_003233	PTKc	cd00192	248	539	1.6e-12
NP_003233	PTKc_Ack_like	cd05040	248	540	3.9e-06
NP_003233	PTKc_c-ros	cd05044	248	540	0.00037
NP_003233	PTKc_Tie	cd05047	248	515	0.0006
NP_003233	PTKc_Met_Ron	cd05058	248	544	0.00097
NP_003233	PTKc_Jak2_Jak3_rpt2	cd05081	248	542	4.8e-06
NP_003233	PTKc_Aatyk1_Aatyk3	cd05087	248	540	0.001
NP_003233	STKc_MAPKKK_Bck1_lik	cd06629	249	510	7.1e-07
NP_003233	STKc_MEKK1_plant	cd06632	249	534	0.0001
NP_003233	STKc_NAK1_like	cd06917	249	548	4.7e-05
NP_003233	PKc	cd00180	250	541	8e-46
NP_003233	PTKc_Syk_like	cd05060	250	543	0.00099
NP_003233	STKc_CMGC	cd05118	250	539	2e-07
NP_003233	STKc_AGC	cd05123	250	544	1.1e-06
NP_003233	STKc_MAST_like	cd05579	250	543	0.00021
NP_003233	STKc_GRK7	cd05607	250	559	0.00076
NP_003233	STKc_MAK_like	cd07830	250	539	0.00062
NP_003233	STKc_CCRK	cd07832	250	539	0.00017
NP_003233	STKc_PAK_II	cd06648	268	557	0.00089
NP_003233	PKc_MEK	cd06615	309	555	3.9e-05
NP_003233	Pkinase	pfam00069	244	538	2.7e-52
NP_003233	ecTbetaR2	pfam08917	47	153	3.7e-74
NP_003233	Pkinase_Tyr	pfam07714	244	538	1.8e-17
NP_003233	TyrKc	smart00219	244	538	2.3e-15
NP_003233	STYKc	smart00221	244	522	1.9e-24
NP_003233	S_TKc	smart00220	254	539	9.7e-26

Please Cite: Peterson, T.A., Adadey, A., Santana-Cruz ,I., Sun, Y., Winder A, Kann, M.G., (2010) DMDM: Domain Mapping of Disease Mutations. Bioinformatics 26 (19), 2458-2459.

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