Results for the gene: CASK

Results for Proteins associated with the Gene: CASK

CASK

8573

O14936 NP_003679 NP_001119527 NP_001119526

NCBI

Known Diseases associated with this Protein:

FG SYNDROME 4

FG SYNDROME 4 (FGS4)

MENTAL RETARDATION AND MICROCEPHALY WITH PONTINE AND CEREBELLAR HYPOPLASIA

MENTAL RETARDATION AND MICROCEPHALY WITH PONTINE AND CEREBELLAR HYPOPLASIA (MICPCH)

MENTAL RETARDATION, X-LINKED, WITH NYSTAGMUS

MENTAL RETARDATION, X-LINKED, WITHOUT NYSTAGMUS

			22 1 18 0 5

Tips:

The Domains on the Default View are decided by HMMER's search E-Value of the Protein against the Domain model.

Clicking a check box on the left will display or hide the corresponding domain(s).

To view the Protein page, either click on the protein links in the box to the left or the blue bar above the Protein's graphic.

Swiss-Prot Protein: O14936

Default View:

RefSeq Protein: NP_003679

Default View:

RefSeq Protein: NP_001119527

Default View:

RefSeq Protein: NP_001119526

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Domains found on the Proteins

Protein ↕	Domain ↕	Domain Accession ↕	Start ↕	End ↕	E-Value ↕
NP_001119526	STKc_ROCK1	cd05622	1	354	5.4e-07
NP_001119526	STKc_PAK	cd06614	1	286	1.8e-24
NP_001119526	PKc_MKK7	cd06618	1	294	9.2e-08
NP_001119526	STKc_TAO3	cd06633	1	310	0.00019
NP_001119526	STKc_TAO1	cd06635	1	310	2.8e-05
NP_001119526	STKc_MAP4K4_6	cd06636	1	276	7.3e-07
NP_001119526	STKc_myosinIIIA	cd06638	1	276	2.6e-10
NP_001119526	STKc_myosinIIIB	cd06639	1	277	1.7e-10
NP_001119526	STKc_PAK4	cd06657	1	302	4.7e-09
NP_001119526	STKc_PAK6	cd06659	1	302	8e-14
NP_001119526	PKc_MEK1	cd06650	1	351	3.8e-05
NP_001119526	STKc_PAK5	cd06658	1	296	5.6e-09
NP_001119526	STKc_p38	cd07851	1	317	1.1e-11
NP_001119526	STKc_JNK	cd07850	1	303	5.7e-08
NP_001119526	STKc_p38delta_MAPK13	cd07879	1	322	0.00045
NP_001119526	STKc_STK10_LOK	cd06644	2	295	1.6e-10
NP_001119526	STKc_PAK1	cd06654	2	299	1e-09
NP_001119526	STKc_MAPK15	cd07852	2	308	1.4e-13
NP_001119526	STKc_JNK2	cd07876	2	314	7.6e-07
NP_001119526	STKc_MAPK4_6	cd07854	2	308	2.4e-07
NP_001119526	STKc_TAO	cd06607	3	310	1.4e-06
NP_001119526	STKc_TAO2	cd06634	3	311	7.5e-07
NP_001119526	STKc_PAK_I	cd06647	3	297	6.5e-15
NP_001119526	STKc_PAK_II	cd06648	3	289	7.2e-14
NP_001119526	PTK_HER3	cd05111	4	288	0.00019
NP_001119526	PTKc_FGFR2	cd05101	4	264	0.00063
NP_001119526	STKc_ROCK2	cd05621	4	322	1e-07
NP_001119526	STKc_PAK2	cd06655	4	300	2.8e-10
NP_001119526	STKc_PAK3	cd06656	4	301	4.6e-10
NP_001119526	STKc_CDK9	cd07865	4	276	5.5e-13
NP_001119526	STKc_p38alpha_MAPK14	cd07877	4	322	7.5e-06
NP_001119526	STKc_p38beta_MAPK11	cd07878	4	317	4.6e-06
NP_001119526	STKc_p38gamma_MAPK12	cd07880	4	317	1.8e-07
NP_001119526	PTKc_ALK_LTK	cd05036	5	273	1.3e-06
NP_001119526	PTKc_Ror	cd05048	5	259	3.1e-05
NP_001119526	PTKc_Musk	cd05050	5	273	4.9e-06
NP_001119526	PTKc_Abl	cd05052	5	275	6e-07
NP_001119526	PTKc_IGF-1R	cd05062	5	278	5.1e-05
NP_001119526	PTKc_InsR	cd05061	5	281	3e-05
NP_001119526	PTKc_TrkA	cd05092	5	282	1.9e-05
NP_001119526	PTKc_TrkC	cd05094	5	323	0.00028
NP_001119526	PTKc_FGFR4	cd05099	5	298	7.3e-05
NP_001119526	PKc_MAPKK_Byr1_like	cd06620	5	283	2.6e-08
NP_001119526	STKc_MAP4K5	cd06646	5	275	2.2e-07
NP_001119526	PKc_MEK2	cd06649	5	354	6e-06
NP_001119526	PTKc_Jak_rpt2	cd05038	6	296	3.3e-06
NP_001119526	PTKc_Csk_like	cd05039	6	274	0.00041
NP_001119526	PTKc_Trk	cd05049	6	273	4.9e-08
NP_001119526	PTKc_FAK	cd05056	6	279	2.6e-07
NP_001119526	PTKc_EGFR_like	cd05057	6	287	5.9e-05
NP_001119526	PTKc_Csk	cd05082	6	274	1.8e-05
NP_001119526	PTKc_Chk	cd05083	6	278	9.9e-05
NP_001119526	PTKc_EGFR	cd05108	6	316	0.0001
NP_001119526	PTKc_HER2	cd05109	6	288	0.0001
NP_001119526	PTKc_HER4	cd05110	6	312	0.0007
NP_001119526	PTKc_Tie2	cd05088	6	294	2.8e-05
NP_001119526	STKc_CDK10	cd07845	6	289	3.7e-11
NP_001119526	STKc_TEY_MAPK_plant	cd07858	6	317	2.5e-11
NP_001119526	PTKc_InsR_like	cd05032	7	278	4.3e-06
NP_001119526	PTKc_EphR_B	cd05065	7	299	0.00051
NP_001119526	PTKc_Lck_Blk	cd05067	7	295	0.00029
NP_001119526	PTKc_Frk_like	cd05068	7	279	1.8e-06
NP_001119526	PTKc_Fyn_Yrk	cd05070	7	279	6.3e-05
NP_001119526	PTKc_Src	cd05071	7	283	0.00032
NP_001119526	PTKc_Ror1	cd05090	7	268	6.2e-05
NP_001119526	PTKc_TrkB	cd05093	7	289	3.8e-05
NP_001119526	PTKc_DDR2	cd05095	7	292	0.00046
NP_001119526	PTKc_DDR_like	cd05097	7	277	0.00035
NP_001119526	PTKc_Itk	cd05112	7	292	1.1e-07
NP_001119526	PTKc_Btk_Bmx	cd05113	7	275	2.5e-05
NP_001119526	STKc_Sty1_Hog1	cd07856	7	291	1.2e-07
NP_001119526	STKc_CDK8	cd07868	7	276	9.6e-05
NP_001119526	STKc_CDC2L6	cd07867	7	276	7.6e-05
NP_001119526	PTKc_Tyk2_rpt2	cd05080	8	297	5.8e-05
NP_001119526	PTKc_Jak1_rpt2	cd05079	8	296	0.00073
NP_001119526	PTKc_Jak2_Jak3_rpt2	cd05081	8	296	3e-06
NP_001119526	PTKc_Tie1	cd05089	8	296	9.9e-06
NP_001119526	STKc_MST1_2	cd06612	8	276	1e-16
NP_001119526	STKc_MAP4K3_like	cd06613	8	275	1.2e-14
NP_001119526	STKc_ASK	cd06624	8	276	8.9e-23
NP_001119526	STKc_TNIK	cd06637	8	276	1.7e-08
NP_001119526	STKc_ERK1_2_like	cd07849	8	310	5e-10
NP_001119526	STKc_ERK5	cd07855	8	315	9.4e-11
NP_001119526	STKc_BUR1	cd07866	8	276	3.8e-12
NP_001119526	STKc_MRCK_alpha	cd05623	9	337	5.5e-09
NP_001119526	STKc_NDR1	cd05628	9	327	3.1e-07
NP_001119526	STKc_SLK_like	cd06611	9	290	1.3e-13
NP_001119526	PKc_MAPKK	cd06605	9	281	2.8e-11
NP_001119526	PKc_MEK	cd06615	9	292	3.2e-10
NP_001119526	PKc_MKK5	cd06619	9	302	1.9e-05
NP_001119526	PKc_MKK4	cd06616	9	293	5.4e-08
NP_001119526	PKc_MAPKK_plant_like	cd06623	9	281	9.4e-19
NP_001119526	STKc_MST4	cd06640	9	299	5e-12
NP_001119526	STKc_MST3	cd06641	9	299	5.1e-11
NP_001119526	STKc_STK25-YSK1	cd06642	9	299	1.2e-14
NP_001119526	STKc_SLK	cd06643	9	293	5.7e-10
NP_001119526	STKc_MAP4K3	cd06645	9	275	1.1e-07
NP_001119526	STKc_MEKK2	cd06652	9	277	2.3e-09
NP_001119526	STKc_MEKK3_like_1	cd06653	9	276	6.8e-10
NP_001119526	PKc_MKK3_6	cd06617	9	297	4e-07
NP_001119526	STKc_PCTAIRE_like	cd07844	9	276	2.6e-14
NP_001119526	STKc_PFTAIRE1	cd07869	9	288	1.7e-06
NP_001119526	STKc_PFTAIRE2	cd07870	9	276	4.8e-09
NP_001119526	STKc_JNK1	cd07875	9	316	4.3e-05
NP_001119526	SPS1	COG0515	9	436	5.6e-62
NP_001119526	PTKc_Tec_like	cd05059	10	257	2.6e-06
NP_001119526	PTKc_Tec_Rlk	cd05114	10	275	1.2e-05
NP_001119526	STKc_ROCK_NDR_like	cd05573	10	318	1.6e-12
NP_001119526	STKc_PDK1	cd05581	10	276	2.9e-26
NP_001119526	STKc_PKA	cd05580	10	301	6.2e-15
NP_001119526	STKc_DMPK_like	cd05597	10	336	7.4e-09
NP_001119526	STKc_LATS	cd05598	10	321	1.5e-06
NP_001119526	STKc_NDR_like	cd05599	10	321	5.5e-08
NP_001119526	STKc_Sid2p_Dbf2p	cd05600	10	302	9.4e-05
NP_001119526	STKc_CRIK	cd05601	10	332	3.9e-10
NP_001119526	STKc_MAST	cd05609	10	322	2e-18
NP_001119526	STKc_phototropin_lik	cd05574	10	284	4.4e-11
NP_001119526	STKc_PRKX_like	cd05612	10	302	2.8e-17
NP_001119526	STKc_MRCK_beta	cd05624	10	336	1.1e-07
NP_001119526	STKc_NDR2	cd05627	10	379	1.1e-06
NP_001119526	STKc_NDR_like_fungal	cd05629	10	379	2.2e-06
NP_001119526	STKc_MST3_like	cd06609	10	296	1.6e-18
NP_001119526	STKc_OSR1_SPAK	cd06610	10	276	1.5e-15
NP_001119526	STKc_myosinIII_like	cd06608	10	276	3e-11
NP_001119526	PKc_MAPKK_Pek1_like	cd06621	10	284	2.8e-13
NP_001119526	PKc_MAPKK_PBS2_like	cd06622	10	297	2.8e-10
NP_001119526	STKc_NAK1_like	cd06917	10	296	4e-13
NP_001119526	STKc_CDKL	cd07833	10	276	1.2e-16
NP_001119526	STKc_CdkB_plant	cd07837	10	277	1.3e-13
NP_001119526	STKc_CDC2L1	cd07843	10	276	1.2e-11
NP_001119526	STKc_CDKL2_3	cd07846	10	276	8.7e-15
NP_001119526	STKc_CDKL1_4	cd07847	10	276	1.3e-19
NP_001119526	STKc_CDKL5	cd07848	10	276	2.9e-10
NP_001119526	STKc_CDK6	cd07862	10	276	6.3e-06
NP_001119526	STKc_CDK12	cd07864	10	276	4.9e-14
NP_001119526	STKc_PCTAIRE3	cd07871	10	276	2.7e-08
NP_001119526	STKc_PCTAIRE2	cd07872	10	296	9.5e-08
NP_001119526	STKc_JNK3	cd07874	10	347	9e-06
NP_001119526	STKc_PCTAIRE1	cd07873	10	290	2.3e-06
NP_001119526	STKc_Nek6_Nek7	cd08224	10	279	9.5e-16
NP_001119526	PTKc_RET	cd05045	11	278	0.001
NP_001119526	PKc_STE	cd05122	11	275	5.5e-31
NP_001119526	STKc_Yank1	cd05578	11	276	4.9e-19
NP_001119526	STKc_GRK4_like	cd05605	11	324	5.9e-23
NP_001119526	STKc_MSK1_N	cd05613	11	292	2.2e-09
NP_001119526	STKc_cPKC_alpha	cd05615	11	323	5.9e-09
NP_001119526	STKc_GRK6	cd05630	11	294	3.5e-14
NP_001119526	STKc_GRK4	cd05631	11	295	1.9e-15
NP_001119526	STKc_GRK5	cd05632	11	295	1.5e-15
NP_001119526	STKc_MAPKKK	cd06606	11	276	8.5e-38
NP_001119526	STKc_MAPKKK_Byr2_lik	cd06628	11	276	4.1e-24
NP_001119526	STKc_YSK4	cd06631	11	276	5.4e-14
NP_001119526	STKc_Cdc7_like	cd06627	11	276	2.9e-19
NP_001119526	STKc_MEKK3	cd06651	11	278	4.9e-13
NP_001119526	STKc_CCRK	cd07832	11	277	1.4e-17
NP_001119526	STKc_MAPK	cd07834	11	315	2.3e-13
NP_001119526	STKc_Pho85	cd07836	11	276	8.4e-20
NP_001119526	STKc_CDK5	cd07839	11	276	1.1e-10
NP_001119526	STKc_CDK7	cd07841	11	289	6.6e-17
NP_001119526	STKc_CDK8_like	cd07842	11	276	1.9e-10
NP_001119526	STKc_NLK	cd07853	11	320	7.6e-08
NP_001119526	STKc_MPK1	cd07857	11	312	6.1e-10
NP_001119526	STKc_TDY_MAPK_plant	cd07859	11	321	5.8e-10
NP_001119526	STKc_CDK2_3	cd07860	11	276	3.2e-18
NP_001119526	STKc_CDK4	cd07863	11	276	4.8e-09
NP_001119526	STKc_Nek	cd08215	11	276	6.7e-45
NP_001119526	STKc_Nek1	cd08218	11	276	2.7e-29
NP_001119526	STKc_Nek3	cd08219	11	276	1.1e-25
NP_001119526	STKc_Nek8	cd08220	11	276	8e-18
NP_001119526	STKc_Nek9	cd08221	11	276	2.1e-12
NP_001119526	STKc_Nek4	cd08223	11	276	5.5e-23
NP_001119526	STKc_Nek5	cd08225	11	276	3.4e-26
NP_001119526	STKc_Nek2	cd08217	11	276	4.5e-17
NP_001119526	STKc_Nek10	cd08528	11	273	6.5e-10
NP_001119526	STKc_CNK2-like	cd08530	11	276	2.6e-13
NP_001119526	PTKc_Src_like	cd05034	12	274	4.8e-05
NP_001119526	PTKc_Axl_like	cd05035	12	275	0.00057
NP_001119526	STKc_CMGC	cd05118	12	276	9.6e-19
NP_001119526	PTKc_Tyro3	cd05074	12	275	3.1e-05
NP_001119526	PTKc_Srm_Brk	cd05148	12	295	7.2e-06
NP_001119526	STKc_MSK_N	cd05583	12	292	9.1e-11
NP_001119526	STKc_cPKC	cd05587	12	351	1.1e-13
NP_001119526	STKc_PKN	cd05589	12	322	5.2e-11
NP_001119526	STKc_cPKC_beta	cd05616	12	352	7.7e-08
NP_001119526	STKc_MSK2_N	cd05614	12	343	4.3e-10
NP_001119526	STKc_MEKK3_like	cd06625	12	276	6.7e-20
NP_001119526	STKc_CDK_like	cd07829	12	276	1.2e-22
NP_001119526	STKc_MOK	cd07831	12	276	1.9e-12
NP_001119526	STKc_MAK_like	cd07830	12	276	6.6e-15
NP_001119526	STKc_CDK1_like	cd07835	12	276	7.6e-20
NP_001119526	STKc_CDK4_6_like	cd07838	12	276	8.1e-14
NP_001119526	STKc_CDK9_like	cd07840	12	276	6.4e-17
NP_001119526	STKc_CDK1_euk	cd07861	12	276	7.9e-21
NP_001119526	STKc_Nek11	cd08222	12	276	9.9e-18
NP_001119526	STKc_Nek6	cd08228	12	279	4e-10
NP_001119526	STKc_Nek7	cd08229	12	276	2.4e-11
NP_001119526	STKc_FA2-like	cd08529	12	276	6.7e-15
NP_001119526	PK_STRAD	cd08216	13	297	6.7e-05
NP_001119526	PK_STRAD_alpha	cd08227	13	357	0.00075
NP_001119526	STKc_MEKK4	cd06626	14	276	8.2e-15
NP_001119526	STKc_RSK_N	cd05582	15	350	5.2e-16
NP_001119526	STKc_p70S6K	cd05584	15	324	2.4e-21
NP_001119526	PTKc	cd00192	16	272	1e-08
NP_001119526	PTKc_Ack_like	cd05040	16	254	7.5e-10
NP_001119526	PTKc_Fes_like	cd05041	16	273	5.4e-06
NP_001119526	PTKc_Tie	cd05047	16	278	2.4e-05
NP_001119526	PTKc_Syk_like	cd05060	16	262	0.00078
NP_001119526	PTK_Jak2_Jak3_rpt1	cd05078	16	272	0.00039
NP_001119526	PTKc_Fes	cd05084	16	273	1e-05
NP_001119526	PTKc_Fer	cd05085	16	276	1.5e-05
NP_001119526	PTKc_Syk	cd05116	16	283	0.0003
NP_001119526	STKc_PKC	cd05570	16	322	3.1e-14
NP_001119526	STKc_PKB	cd05571	16	339	7.2e-18
NP_001119526	STKc_aPKC	cd05588	16	352	9.5e-10
NP_001119526	STKc_nPKC_eta	cd05590	16	335	4.3e-17
NP_001119526	STKc_nPKC_epsilon	cd05591	16	335	2.7e-09
NP_001119526	STKc_nPKC_theta_delt	cd05592	16	324	1.4e-13
NP_001119526	STKc_PKB_gamma	cd05593	16	341	1e-09
NP_001119526	STKc_PKB_alpha	cd05594	16	337	9.1e-12
NP_001119526	STKc_PKB_beta	cd05595	16	339	3.1e-09
NP_001119526	STKc_SGK2	cd05603	16	327	2.5e-10
NP_001119526	STKc_SGK1	cd05602	16	336	1.5e-08
NP_001119526	STKc_SGK3	cd05604	16	336	3.6e-07
NP_001119526	STKc_SGK	cd05575	16	334	2.3e-09
NP_001119526	STKc_aPKC_zeta	cd05617	16	358	7e-09
NP_001119526	STKc_nPKC_theta	cd05619	16	325	7.5e-10
NP_001119526	STKc_nPKC_delta	cd05620	16	324	8.6e-06
NP_001119526	STKc_aPKC_iota	cd05618	16	358	3.5e-07
NP_001119526	STKc_MAPKKK_Bck1_lik	cd06629	16	276	6.6e-10
NP_001119526	STKc_MEKK1	cd06630	16	277	1.8e-13
NP_001119526	STKc_MEKK1_plant	cd06632	16	276	1.9e-16
NP_001119526	STKc_beta_ARK	cd05606	17	295	3.8e-09
NP_001119526	STKc_GRK3	cd05633	17	296	1.4e-07
NP_001119526	PKc	cd00180	18	274	1.1e-69
NP_001119526	PTKc_Lyn	cd05072	18	274	2e-05
NP_001119526	PTKc_Zap-70	cd05115	18	285	2e-05
NP_001119526	STKc_AGC	cd05123	18	276	3e-25
NP_001119526	STKc_cGK_PKG	cd05572	18	283	4.6e-16
NP_001119526	STKc_GRK	cd05577	18	290	3.8e-13
NP_001119526	STKc_MAST_like	cd05579	18	281	1.3e-18
NP_001119526	STKc_YPK1_like	cd05585	18	321	1e-09
NP_001119526	STKc_Sck1_like	cd05586	18	383	1.9e-08
NP_001119526	STKc_GRK1	cd05608	18	293	9.7e-17
NP_001119526	STKc_GRK7	cd05607	18	303	2.1e-16
NP_001119526	STKc_Rim15_like	cd05611	18	280	1.8e-07
NP_001119526	PTKc_Yes	cd05069	22	279	2.3e-05
NP_001119526	PTKc_Hck	cd05073	23	271	4.7e-05
NP_001119526	PDZ_signaling	cd00992	488	568	1.5e-21
NP_001119526	PDZ	cd00136	499	568	1.6e-12
NP_001119526	SH3	cd00174	593	656	7.4e-18
NP_001119526	Gmk	COG0194	703	896	6.6e-11
NP_001119526	GMPK	cd00071	713	879	8.3e-17
NP_001119526	Pkinase	pfam00069	12	276	4.7e-83
NP_001119526	L27	pfam02828	346	397	3.9e-17
NP_001119526	L27	pfam02828	405	454	9.4e-19
NP_001119526	PDZ	pfam00595	490	568	3.8e-21
NP_001119526	SH3_1	pfam00018	595	651	7e-05
NP_001119526	Guanylate_kin	pfam00625	711	885	5.2e-82
NP_001119526	Pkinase_Tyr	pfam07714	12	271	3.2e-12
NP_001119526	TyrKc	smart00219	12	271	7.7e-12
NP_001119526	STYKc	smart00221	12	276	1.6e-89
NP_001119526	S_TKc	smart00220	22	276	3.1e-99
NP_001119526	KIND	smart00750	102	284	4.4e-05
NP_001119526	L27	smart00569	346	401	3.6e-15
NP_001119526	L27	smart00569	405	458	2.4e-16
NP_001119526	PDZ	smart00228	487	571	1e-17
NP_001119526	SH3	smart00326	590	657	2.4e-15
NP_001119526	SH3_2	pfam07653	593	656	4.7e-14
NP_001119526	GuKc	smart00072	710	886	2.8e-76

Please Cite: Peterson, T.A., Adadey, A., Santana-Cruz ,I., Sun, Y., Winder A, Kann, M.G., (2010) DMDM: Domain Mapping of Disease Mutations. Bioinformatics 26 (19), 2458-2459.

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