Results for the gene: ACVRL1

Results for Proteins associated with the Gene: ACVRL1

ACVRL1

94

P37023 NP_001070869 NP_000011

NCBI

Known Diseases associated with this Protein:

PULMONARY ARTERIAL HYPERTENSION, HEREDITARY HEMORRHAGIC TELANGIECTASIA-R

PULMONARY ARTERIAL HYPERTENSION, HEREDITARY HEMORRHAGIC TELANGIECTASIA-RELATED

TELANGIECTASIA, HEREDITARY HEMORRHAGIC, 2 (HHT2)

TELANGIECTASIA, HEREDITARY HEMORRHAGIC, TYPE 2

TELANGIECTASIA, HEREDITARY HEMORRHAGIC, TYPE II

			80 8 11 0 77

Tips:

The Domains on the Default View are decided by HMMER's search E-Value of the Protein against the Domain model.

Clicking a check box on the left will display or hide the corresponding domain(s).

To view the Protein page, either click on the protein links in the box to the left or the blue bar above the Protein's graphic.

Default View: TGF_beta_GS - pfam08515 GS - smart00467 STYKc - smart00221 Pkinase_Tyr - pfam07714 TyrKc - smart00219 S_TKc - smart00220	Swiss-Prot Protein: P37023 Identical to: NP_001070869, NP_000011 Default View:

RefSeq Protein: NP_001070869

Default View:

RefSeq Protein: NP_000011

Default View:

Domains found on the Proteins

Protein ↕	Domain ↕	Domain Accession ↕	Start ↕	End ↕	E-Value ↕
NP_000011	STKc_myosinIIIA	cd06638	183	460	0.00035
NP_000011	STKc_MAP4K4_6	cd06636	185	461	0.00027
NP_000011	PTKc_FGFR1	cd05098	186	496	9.4e-05
NP_000011	PTKc_FGFR2	cd05101	187	500	0.00021
NP_000011	STKc_PAK_II	cd06648	188	502	1.2e-05
NP_000011	PTKc_FGFR	cd05053	190	494	3.7e-07
NP_000011	PTKc_FGFR4	cd05099	190	497	1e-05
NP_000011	PTKc_EGFR_like	cd05057	191	503	6.2e-07
NP_000011	STKc_PAK	cd06614	191	468	4.3e-08
NP_000011	PTKc_Abl	cd05052	192	493	3.4e-07
NP_000011	STKc_ASK	cd06624	192	491	0.00011
NP_000011	STKc_MAP4K3	cd06645	193	493	0.0004
NP_000011	STKc_MAP4K5	cd06646	193	490	2.1e-05
NP_000011	STKc_BUR1	cd07866	193	487	0.001
NP_000011	PTKc_TrkA	cd05092	194	491	1.7e-05
NP_000011	PTKc_EGFR	cd05108	194	499	0.00062
NP_000011	PTKc_HER2	cd05109	194	503	4.9e-05
NP_000011	PTK_HER3	cd05111	195	503	1.3e-06
NP_000011	STKc_TNIK	cd06637	195	461	2.9e-05
NP_000011	STKc_CDK12	cd07864	195	492	1.3e-05
NP_000011	PTKc_Ror	cd05048	196	435	1.4e-07
NP_000011	PTKc_ALK_LTK	cd05036	196	491	2.9e-08
NP_000011	PTKc_FAK	cd05056	196	497	1.1e-06
NP_000011	PTKc_EphR_A2	cd05063	196	493	0.00038
NP_000011	PTKc_EphR_A10	cd05064	196	493	0.00019
NP_000011	PTKc_Frk_like	cd05068	196	492	8.5e-11
NP_000011	PTKc_Csk	cd05082	196	492	5.6e-08
NP_000011	PTKc_Ror1	cd05090	196	492	9.3e-05
NP_000011	PTKc_Ror2	cd05091	196	492	7.9e-05
NP_000011	PTKc_TrkC	cd05094	196	503	0.00055
NP_000011	PTKc_DDR_like	cd05097	196	491	0.00013
NP_000011	PTKc_DDR2	cd05095	196	491	0.00019
NP_000011	PTKc_TrkB	cd05093	196	503	0.00052
NP_000011	PTKc_EphR	cd05033	197	493	6.2e-09
NP_000011	PTKc_Jak_rpt2	cd05038	197	493	3.1e-09
NP_000011	PTK_Ryk	cd05043	197	438	0.00084
NP_000011	PTK_CCK4	cd05046	197	491	5.8e-05
NP_000011	PTKc_Trk	cd05049	197	491	4.5e-10
NP_000011	PTKc_Musk	cd05050	197	491	5e-07
NP_000011	PTKc_DDR	cd05051	197	491	7.8e-06
NP_000011	PTKc_InsR	cd05061	197	503	0.00037
NP_000011	PTKc_IGF-1R	cd05062	197	491	0.00061
NP_000011	PTKc_Lck_Blk	cd05067	197	492	5.6e-06
NP_000011	PTKc_Yes	cd05069	197	492	1.3e-06
NP_000011	PTKc_Fyn_Yrk	cd05070	197	492	4.8e-06
NP_000011	PTKc_Src	cd05071	197	494	4.4e-05
NP_000011	PTKc_Hck	cd05073	197	492	2.9e-05
NP_000011	PTKc_Itk	cd05112	197	490	2.1e-06
NP_000011	PTKc_Btk_Bmx	cd05113	197	490	9.4e-08
NP_000011	PTKc_Lyn	cd05072	197	492	5.5e-07
NP_000011	PTKc_Tec_Rlk	cd05114	197	490	9.8e-05
NP_000011	STKc_MST4	cd06640	197	489	0.00011
NP_000011	STKc_MST3	cd06641	197	503	5.1e-05
NP_000011	STKc_STK25-YSK1	cd06642	197	491	4.7e-06
NP_000011	STKc_CDK10	cd07845	197	503	5.5e-05
NP_000011	PTKc_InsR_like	cd05032	198	491	1.4e-06
NP_000011	STKc_MST1_2	cd06612	198	461	1.5e-09
NP_000011	STKc_MAP4K3_like	cd06613	198	487	1e-07
NP_000011	PTKc_Csk_like	cd05039	199	445	3.8e-10
NP_000011	PTKc_Tec_like	cd05059	199	490	1.8e-07
NP_000011	PTKc_EphR_B	cd05065	199	493	6.6e-05
NP_000011	PTKc_EphR_A	cd05066	199	493	0.00031
NP_000011	PTKc_Jak1_rpt2	cd05079	199	493	0.00017
NP_000011	PTKc_Jak2_Jak3_rpt2	cd05081	199	493	1.2e-07
NP_000011	STKc_myosinIII_like	cd06608	199	461	8.6e-07
NP_000011	STKc_Nek6_Nek7	cd08224	199	494	1.7e-05
NP_000011	STKc_Nek7	cd08229	199	494	0.00016
NP_000011	PTKc_Src_like	cd05034	200	492	2.8e-09
NP_000011	PTKc_Tyk2_rpt2	cd05080	200	494	5.7e-06
NP_000011	PTKc_Chk	cd05083	200	492	6e-06
NP_000011	PTKc_Tie2	cd05088	200	494	6.6e-05
NP_000011	PTKc_Tie1	cd05089	200	503	0.00046
NP_000011	STKc_PDK1	cd05581	200	473	9.7e-07
NP_000011	PKc_MAPKK	cd06605	200	479	0.00052
NP_000011	STKc_MST3_like	cd06609	200	500	0.00016
NP_000011	STKc_OSR1_SPAK	cd06610	200	488	7.3e-07
NP_000011	PKc_MEK	cd06615	200	489	0.00099
NP_000011	PKc_MKK3_6	cd06617	200	477	0.00028
NP_000011	STKc_NAK1_like	cd06917	200	503	2.4e-06
NP_000011	STKc_CdkB_plant	cd07837	200	491	7.9e-05
NP_000011	STKc_CDKL2_3	cd07846	200	490	0.00022
NP_000011	STKc_CDKL1_4	cd07847	200	491	1.8e-05
NP_000011	PKc_STE	cd05122	201	482	1.9e-09
NP_000011	STKc_Yank1	cd05578	201	498	0.00021
NP_000011	STKc_GRK4_like	cd05605	201	501	0.00099
NP_000011	STKc_MAPKKK	cd06606	201	483	1.4e-12
NP_000011	STKc_Cdc7_like	cd06627	201	483	4.3e-08
NP_000011	STKc_CCRK	cd07832	201	465	3.4e-07
NP_000011	STKc_CDK5	cd07839	201	490	0.0009
NP_000011	STKc_CDK4	cd07863	201	491	0.00027
NP_000011	STKc_Nek	cd08215	201	491	8.7e-08
NP_000011	STKc_Nek3	cd08219	201	489	0.00039
NP_000011	STKc_Nek8	cd08220	201	461	7.7e-05
NP_000011	STKc_Nek4	cd08223	201	460	0.00038
NP_000011	STKc_FA2-like	cd08529	201	435	8.2e-05
NP_000011	STKc_CNK2-like	cd08530	201	494	2.2e-06
NP_000011	PTKc_Axl_like	cd05035	202	493	6.4e-06
NP_000011	PTKc_Tyro3	cd05074	202	493	9.4e-06
NP_000011	PTKc_Axl	cd05075	202	493	0.00012
NP_000011	STKc_MAPKKK_Bck1_lik	cd06629	202	461	3.2e-05
NP_000011	PTKc_Srm_Brk	cd05148	203	492	3.6e-10
NP_000011	PKc_MAPKK_plant_like	cd06623	203	494	1.3e-06
NP_000011	STKc_MEKK4	cd06626	203	489	7.5e-07
NP_000011	STKc_MAK_like	cd07830	204	488	0.00082
NP_000011	STKc_CDKL	cd07833	204	483	0.00019
NP_000011	STKc_CDK9_like	cd07840	204	483	0.0006
NP_000011	STKc_Nek2	cd08217	204	491	0.00041
NP_000011	STKc_CMGC	cd05118	205	483	1.3e-08
NP_000011	STKc_CDK_like	cd07829	205	485	0.0002
NP_000011	STKc_Nek9	cd08221	205	466	1.1e-05
NP_000011	PTKc	cd00192	206	490	3.9e-12
NP_000011	PTKc_Ack_like	cd05040	206	491	9.5e-08
NP_000011	PTKc_Fes_like	cd05041	206	444	5.7e-07
NP_000011	PTKc_Aatyk	cd05042	206	491	2.8e-07
NP_000011	PTKc_c-ros	cd05044	206	491	6.2e-05
NP_000011	PTKc_Tie	cd05047	206	494	0.00012
NP_000011	PTKc_Met_Ron	cd05058	206	495	2.7e-05
NP_000011	PTKc_Syk_like	cd05060	206	447	8.4e-05
NP_000011	PTKc_Fes	cd05084	206	491	0.00021
NP_000011	PTKc_Fer	cd05085	206	491	2.3e-05
NP_000011	PTKc_Aatyk2	cd05086	206	491	2.4e-05
NP_000011	STKc_MEKK3_like	cd06625	206	488	9.3e-05
NP_000011	STKc_MEKK1_plant	cd06632	206	485	2.1e-05
NP_000011	PKc	cd00180	208	489	1.3e-49
NP_000011	STKc_AGC	cd05123	208	487	5.5e-05
NP_000011	STKc_GRK	cd05577	208	475	7.1e-05
NP_000011	STKc_GRK7	cd05607	208	475	0.00039
NP_000011	Activin_recp	pfam01064	32	103	1.4e-09
NP_000011	Pkinase	pfam00069	202	489	9.5e-71
NP_000011	TGF_beta_GS	pfam08515	172	200	7.4e-14
NP_000011	GS	smart00467	172	202	1.3e-14
NP_000011	Pkinase_Tyr	pfam07714	202	489	1.5e-17
NP_000011	TyrKc	smart00219	202	489	5.6e-14
NP_000011	STYKc	smart00221	202	474	8.9e-16
NP_000011	S_TKc	smart00220	212	493	2.9e-16

Please Cite: Peterson, T.A., Adadey, A., Santana-Cruz ,I., Sun, Y., Winder A, Kann, M.G., (2010) DMDM: Domain Mapping of Disease Mutations. Bioinformatics 26 (19), 2458-2459.

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