Results for the protein: P00326

Results for the Protein: P00326

113398

126

ADH1C

NCBI, UniProt

ADH1G_HUMAN RecName: Full=Alcohol dehydrogenase 1C; AltName: Full=Alcohol dehydrogenase subunit gamma

Known Diseases associated with this Protein:
ALCOHOL DEPENDENCE, PROTECTION AGAINST
PARKINSON DISEASE, SUSCEPTIBILITY TO

3

6

3

3

3

Tips:

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Swiss-Prot Protein: P00326

Identical to: NP_000660

Default View:

Domains found on the Protein

Domain ↕	CD Accession ↕	E-Value ↕	Start ↕	End ↕
alcohol_DH_class_I_I	cd08299	7.7e-305	3	375
CAD1	cd05283	1.4e-13	6	374
AdhP	COG1064	8.2e-49	7	375
liver_alcohol_DH_lik	cd08277	2.6e-250	8	374
benzyl_alcohol_DH	cd08278	2.9e-82	8	374
alcohol_DH_class_III	cd08300	1.1e-196	8	374
alcohol_DH_plants	cd08301	1.5e-189	8	374
AdhC	COG1062	5.6e-195	8	375
p53_inducible_oxidor	cd05276	1.7e-07	10	369
FDH_like	cd05278	2.3e-18	10	375
Zn_ADH1	cd05279	2.3e-262	10	374
arabinose_DH_like	cd05284	1.6e-17	10	375
MDR_like_2	cd05289	3.8e-08	10	373
glucose_DH	cd08230	6.1e-06	10	375
MDR_TM0436_like	cd08231	3.6e-23	10	375
butanediol_DH_like	cd08233	8.2e-19	10	370
threonine_DH_like	cd08234	5.4e-18	10	374
iditol_2_DH_like	cd08235	8e-16	10	374
sugar_DH	cd08236	5.4e-18	10	373
THR_DH_like	cd08239	5.2e-17	10	375
6_hydroxyhexanoate_d	cd08240	1.2e-16	10	375
QOR1	cd08241	3.5e-10	10	374
enoyl_reductase_like	cd08249	2.4e-09	10	375
hydroxyacyl_CoA_DH	cd08254	1.2e-29	10	375
Zn_ADH4	cd08258	1.7e-11	10	340
Zn_ADH7	cd08261	2.6e-19	10	375
MDR2	cd08268	2.1e-08	10	375
MDR5	cd08271	8.8e-07	10	372
Zn_ADH6	cd08260	4e-18	10	375
Zn_ADH_class_III	cd08279	3.5e-145	10	374
MDR6	cd08272	4.6e-09	10	375
liver_ADH_like1	cd08281	1.6e-77	10	374
NADP_ADH	cd08285	5.6e-18	10	375
FDH_like_ADH2	cd08286	9.2e-14	10	375
ETR	cd08290	5.7e-05	10	375
CAD3	cd08297	3.1e-15	10	375
CAD2	cd08298	2.6e-11	10	373
Qor	COG0604	1.2e-30	10	375
TDH	cd05281	4.1e-14	11	375
QOR2	cd05286	5.7e-10	11	375
CAD	cd08245	6.4e-16	11	373
zeta_crystallin	cd08253	1.1e-08	11	375
Zn_ADH5	cd08259	1.9e-16	11	374
Zn_ADH8	cd08262	3e-08	11	375
Zn_ADH10	cd08263	6e-62	11	374
Zn_ADH_like2	cd08264	2.8e-07	11	373
Zn_ADH3	cd08265	5.9e-12	11	374
Zn_ADH_like1	cd08266	8.1e-14	11	372
FDH_like_ADH3	cd08287	1.6e-14	11	349
CAD_like	cd08296	7.2e-12	11	374
Tdh	COG1063	1.3e-54	11	375
sorbitol_DH	cd05285	2.1e-19	12	375
Zn_ADH2	cd08256	3.1e-11	12	373
PFDH_like	cd08282	2.5e-14	12	375
ETR_like	cd05282	2.2e-05	13	371
MDR1	cd08267	3e-10	13	373
MDR7	cd08276	4.5e-11	13	372
FDH_like_1	cd08283	1.8e-14	13	375
FDH_like_2	cd08284	5.3e-20	13	375
MDR3	cd08275	3.5e-06	14	375
Zn_ADH9	cd08269	3.7e-08	18	374
MDR8	cd08273	2.5e-06	18	370
idonate-5-DH	cd08232	9.6e-12	23	375
Mgc45594_like	cd08250	0.00072	23	375
polyketide_synthase	cd08251	0.00051	28	373
2-desacetyl-2-hydrox	cd08255	6.2e-06	28	373
enoyl_red	cd05195	8.4e-07	35	374
MDR	cd05188	9.5e-91	36	363
PGDH	cd05288	0.00086	80	374
ADH_zinc_N	pfam00107	7.5e-32	203	334
ADH_N	pfam08240	4.8e-35	34	161
PKS_ER	smart00829	0.00037	38	373

Table of Mutations found on the Protein

Source ↕	Mut_ID ↕	Class ↕	HGVS ↕	Disease ↕
dbSNP	rs1693482	Polymorphism	p.ARG272GLN	N/A
dbSNP	rs35385902	Polymorphism	p.ARG48HIS	N/A
dbSNP	rs698	Polymorphism	p.ILE350PHE	N/A
Swiss-Prot	VAR_000429	Polymorphism	p.ILE350VAL	N/A
Swiss-Prot	VAR_023993	Polymorphism	p.PRO166SER	N/A
Swiss-Prot	VAR_023994	Polymorphism	p.PRO352THR	N/A
OMIM	103730.0001	Disease	p.ARG272GLN	ALCOHOL DEPENDENCE, PROTECTION AGAINST
OMIM	103730.0003	Disease	p.GLY78TER	PARKINSON DISEASE, SUSCEPTIBILITY TO
OMIM	103730.0002	Disease	p.ILE350VAL	ALCOHOL DEPENDENCE, PROTECTION AGAINST

Please Cite: Peterson, T.A., Adadey, A., Santana-Cruz ,I., Sun, Y., Winder A, Kann, M.G., (2010) DMDM: Domain Mapping of Disease Mutations. Bioinformatics 26 (19), 2458-2459.

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