Results for the protein: P35626

Results for the Protein: P35626

116241253

157

ADRBK2

NCBI, UniProt

ARBK2_HUMAN RecName: Full=Beta-adrenergic receptor kinase 2; Short=Beta-ARK-2; AltName: Full=G-protein-coupled receptor kinase 3

			0 4 0 0 4

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Swiss-Prot Protein: P35626

Identical to: NP_005151

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Domains found on the Protein

Domain ↕	CD Accession ↕	E-Value ↕	Start ↕	End ↕
STKc_ROCK2	cd05621	6.9e-15	150	518
STKc_ROCK1	cd05622	1.4e-16	150	514
STKc_PAK1	cd06654	1.7e-07	151	481
STKc_PAK3	cd06656	2.9e-07	151	482
STKc_PAK5	cd06658	2.6e-06	166	467
STKc_PAK6	cd06659	8.2e-08	166	481
STKc_PAK4	cd06657	2.9e-06	168	481
STKc_JNK2	cd07876	0.00015	168	554
STKc_myosinIIIB	cd06639	4.1e-08	171	454
STKc_myosinIIIA	cd06638	2.2e-08	171	453
STKc_PAK_I	cd06647	6.6e-06	172	478
STKc_PAK2	cd06655	3.6e-07	172	482
STKc_PAK	cd06614	7.8e-15	175	466
STKc_p38alpha_MAPK14	cd07877	0.00016	175	530
STKc_JNK3	cd07874	0.00047	175	566
STKc_MAP4K4_6	cd06636	0.0002	176	453
STKc_JNK	cd07850	6.4e-05	176	525
STKc_p38	cd07851	1.8e-07	177	503
STKc_p38beta_MAPK11	cd07878	4.5e-05	177	534
STKc_CDK9	cd07865	2.7e-08	178	453
STKc_p38gamma_MAPK12	cd07880	1.3e-05	178	510
STKc_PAK_II	cd06648	3.2e-10	179	471
STKc_MAPK15	cd07852	2.5e-06	180	496
STKc_Sty1_Hog1	cd07856	1.2e-06	180	500
PKc_MKK7	cd06618	3e-10	181	465
STKc_MAP4K3	cd06645	1.9e-08	181	433
STKc_MAP4K5	cd06646	6.7e-08	181	433
PTKc_EGFR	cd05108	0.00084	182	472
STKc_ASK	cd06624	4.5e-14	182	453
PTKc_EGFR_like	cd05057	0.00051	183	440
STKc_STK10_LOK	cd06644	2.2e-07	183	477
PTKc_ALK_LTK	cd05036	6.2e-05	184	430
PTKc_Abl	cd05052	0.00073	184	452
PTKc_FAK	cd05056	0.0003	184	452
PTKc_InsR	cd05061	0.00027	184	458
PTKc_Frk_like	cd05068	5.7e-05	184	452
PTKc_Csk	cd05082	0.00059	184	451
STKc_TNIK	cd06637	3e-06	184	453
STKc_TEY_MAPK_plant	cd07858	1.3e-07	184	534
PTKc_Ror	cd05048	1e-05	185	424
PTKc_Ror1	cd05090	0.00014	185	440
PTKc_TrkA	cd05092	0.00028	185	453
PTKc_TrkB	cd05093	0.00056	185	464
PKc_MAPKK_Byr1_like	cd06620	1.4e-06	185	467
PKc_MEK2	cd06649	1.5e-05	185	524
PKc_MEK1	cd06650	0.00011	185	528
STKc_PCTAIRE_like	cd07844	2.2e-10	185	488
STKc_MAPK4_6	cd07854	0.00096	185	510
STKc_CDK12	cd07864	3.8e-08	185	453
PTKc_InsR_like	cd05032	0.00039	186	426
PTKc_Src_like	cd05034	0.00042	186	428
PTKc_Chk	cd05083	2e-05	186	449
PTKc_Itk	cd05112	0.00027	186	451
PTKc_Btk_Bmx	cd05113	0.00094	186	447
PKc_MKK4	cd06616	7.7e-09	186	471
STKc_MAP4K3_like	cd06613	2.1e-11	187	452
STKc_CDK10	cd07845	6.6e-10	187	467
STKc_BUR1	cd07866	6.1e-07	187	453
STKc_PFTAIRE2	cd07870	1.1e-07	187	488
STKc_PCTAIRE3	cd07871	1.1e-06	187	453
STKc_PCTAIRE2	cd07872	4.2e-06	187	465
STKc_PCTAIRE1	cd07873	4.4e-05	187	465
STKc_PFTAIRE1	cd07869	4.6e-05	187	500
PTKc_Jak_rpt2	cd05038	2.8e-05	188	425
STKc_SLK_like	cd06611	4.8e-09	188	464
STKc_SLK	cd06643	1.2e-06	188	479
STKc_CDC2L6	cd07867	4.5e-06	188	488
STKc_CDK8	cd07868	1.5e-05	188	488
STKc_Nek6_Nek7	cd08224	1.2e-12	188	449
STKc_Nek6	cd08228	6.6e-09	188	449
STKc_Nek7	cd08229	6.8e-12	188	451
PTKc_Srm_Brk	cd05148	0.00064	189	428
STKc_ROCK_NDR_like	cd05573	6.2e-29	189	507
STKc_phototropin_lik	cd05574	1.4e-34	189	479
STKc_PKA	cd05580	2.5e-67	189	491
STKc_PDK1	cd05581	1.7e-46	189	453
STKc_DMPK_like	cd05597	2.4e-38	189	518
STKc_LATS	cd05598	2e-18	189	530
STKc_NDR_like	cd05599	3e-19	189	510
STKc_Sid2p_Dbf2p	cd05600	1.7e-15	189	542
STKc_MAST	cd05609	1.7e-34	189	484
STKc_PRKX_like	cd05612	3.1e-55	189	492
STKc_CRIK	cd05601	3.4e-17	189	513
STKc_MRCK_alpha	cd05623	1.1e-15	189	518
STKc_MRCK_beta	cd05624	5.6e-21	189	517
STKc_LATS1	cd05625	1.7e-13	189	527
STKc_LATS2	cd05626	2e-10	189	530
STKc_NDR2	cd05627	1.8e-17	189	547
STKc_NDR1	cd05628	4.9e-14	189	537
STKc_NDR_like_fungal	cd05629	7.5e-27	189	530
PKc_MAPKK	cd06605	1.5e-11	189	458
STKc_myosinIII_like	cd06608	2.4e-08	189	402
STKc_MST3_like	cd06609	3.8e-11	189	463
STKc_OSR1_SPAK	cd06610	1e-11	189	453
STKc_MST1_2	cd06612	2.3e-11	189	453
PKc_MKK3_6	cd06617	3.5e-09	189	472
PKc_MKK5	cd06619	4.2e-05	189	467
PKc_MAPKK_Pek1_like	cd06621	1.1e-08	189	462
PKc_MAPKK_plant_like	cd06623	7.6e-16	189	458
STKc_MEKK3_like	cd06625	1.7e-14	189	453
PKc_MAPKK_PBS2_like	cd06622	1e-07	189	496
STKc_MST4	cd06640	1.8e-08	189	474
STKc_STK25-YSK1	cd06642	6.5e-09	189	463
STKc_MST3	cd06641	1.5e-08	189	470
STKc_MEKK2	cd06652	1.6e-06	189	454
STKc_MEKK3_like_1	cd06653	4.2e-09	189	453
PKc_MEK	cd06615	6.9e-08	189	471
STKc_CDKL	cd07833	1.4e-07	189	453
STKc_CdkB_plant	cd07837	2e-13	189	454
STKc_CDKL2_3	cd07846	5.7e-06	189	453
STKc_CDKL1_4	cd07847	2.8e-07	189	488
STKc_CDKL5	cd07848	0.00014	189	457
STKc_ERK1_2_like	cd07849	1.6e-06	189	506
STKc_CDK6	cd07862	0.00014	189	461
SPS1	COG0515	6.8e-52	189	614
PKc_STE	cd05122	5.6e-19	190	452
STKc_Yank1	cd05578	1.1e-81	190	453
STKc_MSK_N	cd05583	5.8e-79	190	472
STKc_cPKC	cd05587	8.9e-62	190	513
STKc_GRK4_like	cd05605	6.2e-99	190	474
STKc_MSK1_N	cd05613	1.1e-60	190	472
STKc_cPKC_alpha	cd05615	1.3e-42	190	513
STKc_MSK2_N	cd05614	2.4e-66	190	514
STKc_cPKC_beta	cd05616	3.1e-43	190	521
STKc_GRK6	cd05630	2.3e-95	190	474
STKc_GRK4	cd05631	2.1e-88	190	474
STKc_GRK5	cd05632	7.8e-88	190	474
STKc_MAPKKK	cd06606	7e-31	190	453
STKc_Cdc7_like	cd06627	7.4e-18	190	453
STKc_MAPKKK_Byr2_lik	cd06628	3.2e-20	190	453
STKc_MEKK1	cd06630	9.8e-11	190	454
STKc_YSK4	cd06631	1.6e-08	190	453
STKc_MEKK3	cd06651	5.9e-09	190	455
STKc_CCRK	cd07832	2.5e-13	190	454
STKc_MAPK	cd07834	1.8e-08	190	509
STKc_Pho85	cd07836	7e-09	190	488
STKc_CDK5	cd07839	1.5e-07	190	453
STKc_CDK7	cd07841	9.1e-10	190	472
STKc_CDK8_like	cd07842	6e-07	190	453
STKc_NLK	cd07853	5.4e-06	190	539
STKc_MPK1	cd07857	1.2e-06	190	505
STKc_TDY_MAPK_plant	cd07859	1.5e-06	190	534
STKc_CDK2_3	cd07860	2.2e-06	190	453
STKc_CDK1_euk	cd07861	1.8e-06	190	488
STKc_CDK4	cd07863	3.1e-06	190	453
STKc_Nek	cd08215	1.2e-18	190	453
STKc_Nek1	cd08218	2.5e-12	190	453
STKc_Nek2	cd08217	1.2e-10	190	453
STKc_Nek3	cd08219	8.8e-14	190	448
STKc_Nek8	cd08220	2.3e-10	190	448
STKc_Nek11	cd08222	5.6e-08	190	453
STKc_Nek4	cd08223	2.1e-07	190	453
STKc_Nek5	cd08225	1.5e-13	190	453
STKc_Nek10	cd08528	1.4e-08	190	445
STKc_FA2-like	cd08529	1.8e-12	190	437
STKc_CNK2-like	cd08530	5.5e-13	190	453
STKc_CMGC	cd05118	4.7e-13	191	453
STKc_PKN	cd05589	1.1e-54	191	512
STKc_MAPKKK_Bck1_lik	cd06629	3.1e-09	191	413
STKc_CDK_like	cd07829	2.7e-15	191	453
STKc_MAK_like	cd07830	1.9e-11	191	453
STKc_CDK1_like	cd07835	7.2e-08	191	482
STKc_CDK4_6_like	cd07838	2.2e-08	191	453
STKc_CDK9_like	cd07840	3.7e-12	191	453
STKc_ERK5	cd07855	9.3e-07	191	499
STKc_NAK1_like	cd06917	5.9e-11	192	463
STKc_CDC2L1	cd07843	6.7e-07	192	453
PK_STRAD	cd08216	0.00042	192	469
STKc_RSK_N	cd05582	4e-72	194	512
STKc_p70S6K	cd05584	4.1e-63	194	514
STKc_MEKK4	cd06626	1.2e-08	194	453
STKc_MOK	cd07831	1.5e-12	194	453
PTKc	cd00192	2.2e-09	195	454
PTKc_Ack_like	cd05040	0.0005	195	426
PTKc_Fes_like	cd05041	1e-05	195	426
PTKc_c-ros	cd05044	0.0001	195	448
PTKc_Met_Ron	cd05058	8.5e-05	195	452
PTKc_Syk_like	cd05060	5.4e-05	195	430
PTKc_Jak2_Jak3_rpt2	cd05081	6.4e-05	195	451
PTKc_Fes	cd05084	4e-06	195	449
PTKc_Syk	cd05116	5.1e-06	195	454
STKc_PKC	cd05570	4.1e-50	195	512
STKc_PKB	cd05571	5.9e-67	195	529
STKc_SGK	cd05575	1.1e-60	195	512
STKc_aPKC	cd05588	1.1e-49	195	530
STKc_nPKC_eta	cd05590	1.3e-54	195	513
STKc_nPKC_epsilon	cd05591	2.8e-48	195	513
STKc_nPKC_theta_delt	cd05592	9.4e-58	195	514
STKc_PKB_gamma	cd05593	1.9e-51	195	520
STKc_PKB_alpha	cd05594	7.6e-54	195	530
STKc_SGK1	cd05602	2.7e-49	195	533
STKc_SGK2	cd05603	3.2e-49	195	528
STKc_SGK3	cd05604	6.1e-49	195	540
STKc_aPKC_zeta	cd05617	2.4e-34	195	513
STKc_aPKC_iota	cd05618	1.9e-34	195	523
STKc_nPKC_theta	cd05619	5.1e-46	195	514
STKc_PKB_beta	cd05595	2.2e-55	195	529
STKc_nPKC_delta	cd05620	2.1e-39	195	514
STKc_MEKK1_plant	cd06632	2.7e-14	195	453
STKc_Nek9	cd08221	1.4e-08	195	453
STKc_beta_ARK	cd05606	2.6e-235	196	473
STKc_GRK3	cd05633	2e-261	196	474
PKc	cd00180	4.7e-65	197	451
PTKc_Zap-70	cd05115	7.6e-05	197	454
STKc_AGC	cd05123	9.9e-125	197	453
STKc_cGK_PKG	cd05572	3.5e-48	197	460
STKc_GRK	cd05577	1.3e-211	197	473
STKc_MAST_like	cd05579	1.6e-35	197	458
STKc_YPK1_like	cd05585	6.9e-70	197	526
STKc_Sck1_like	cd05586	6.3e-65	197	572
STKc_GRK7	cd05607	1.3e-74	197	473
STKc_GRK1	cd05608	2.4e-84	197	473
STKc_Rim15_like	cd05611	1.3e-14	197	459
PH_GRK2_subgroup	cd01240	4.8e-64	557	669
PH	cd00821	6e-11	561	650
PH-like	cd00900	3.4e-09	561	650
RGS	pfam00615	4e-31	54	174
Pkinase	pfam00069	5e-99	191	453
PH	pfam00169	1.5e-12	559	652
RGS	smart00315	1.8e-28	54	174
Pkinase_Tyr	pfam07714	1.4e-12	191	453
TyrKc	smart00219	3.5e-11	191	453
STYKc	smart00221	4.9e-71	191	453
S_TKc	smart00220	8e-85	201	453
S_TK_X	smart00133	1.2e-12	454	530
PH	smart00233	7.5e-09	559	652

Table of Mutations found on the Protein

Source ↕	Mut_ID ↕	Class ↕	HGVS ↕	Disease ↕
Swiss-Prot	VAR_040382	Polymorphism	p.ARG104LYS	N/A
Swiss-Prot	VAR_040380	Polymorphism	p.ARG50SER	N/A
Swiss-Prot	VAR_040381	Polymorphism	p.ASN60SER	N/A
Swiss-Prot	VAR_028005	Polymorphism	p.VAL409MET	N/A

Please Cite: Peterson, T.A., Adadey, A., Santana-Cruz ,I., Sun, Y., Winder A, Kann, M.G., (2010) DMDM: Domain Mapping of Disease Mutations. Bioinformatics 26 (19), 2458-2459.

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