Home News About DMDM Database Statistics Research Publications Contact  

Results for the Protein: P42679
1169123

MATK_HUMAN RecName: Full=Megakaryocyte-associated tyrosine-protein kinase; AltName: Full=CSK homologous kinase; Short=CHK; AltName: Full=Hematopoietic consensus tyrosine-lacking kinase; AltName: Full=Protein kinase HYL; AltName: Full=Tyrosine-protein kinase CTK
0
3
0
1
2
Tips:
 The Domains on the Default View are decided by the Domain's E-Value.

 Clicking a check box will display or hide the correlated domain.

 To view the Gene page, either click on the link to the left or the blue bar above the Protein's graphic.



Default View:

SH3 - smart00326
SH3 - cd00174
PTKc_VEGFR - cd05054
SH2 - smart00252
PTKc_PDGFR_beta - cd05107
PTKc_Kit - cd05104
SH2 - cd00173
SH2 - pfam00017
PTKc_PDGFR_alpha - cd05105
PTKc_CSF-1R - cd05106
PTKc_PDGFR - cd05055
STKc_PAK6 - cd06659
PKc_MKK5 - cd06619
STKc_PAK1 - cd06654
PTK_Tyk2_rpt1 - cd05076
STKc_PAK5 - cd06658
STKc_PAK3 - cd06656
STKc_PAK2 - cd06655
STKc_PAK_I - cd06647
PTKc_FGFR1 - cd05098
STKc_PAK - cd06614
PTKc_FGFR2 - cd05101
STKc_p38gamma_MAPK12 - cd07880
STKc_PAK4 - cd06657
STKc_TAO - cd06607
STKc_PAK_II - cd06648
STKc_TAO2 - cd06634
STKc_STK10_LOK - cd06644
PKc_MKK7 - cd06618
STKc_MAP4K3 - cd06645
STKc_MAP4K5 - cd06646
STKc_CDK9 - cd07865
STKc_PFTAIRE2 - cd07870
STKc_myosinIIIA - cd06638
PTKc_FGFR4 - cd05099
PTKc_FGFR3 - cd05100
STKc_ASK - cd06624
PTKc_VEGFR2 - cd05103
STKc_CDK10 - cd07845
PTKc_VEGFR3 - cd05102
PTK_HER3 - cd05111
PTKc_Lyn - cd05072
PTKc_Src - cd05071
PTKc_Hck - cd05073
STKc_CDK12 - cd07864
PTKc_Srm_Brk - cd05148
PTKc_Chk - cd05083
PTKc_Csk - cd05082
PTKc_Frk_like - cd05068
PTKc_Fyn_Yrk - cd05070
PTKc_Csk_like - cd05039
PTKc_Src_like - cd05034
PTKc_InsR_like - cd05032
PTKc_FGFR - cd05053
PTKc_Abl - cd05052
PTKc_FAK - cd05056
PTKc_Lck_Blk - cd05067
PTKc_Yes - cd05069
PTKc_IGF-1R - cd05062
PTKc_InsR - cd05061
PTKc_HER4 - cd05110
STKc_SLK - cd06643
PTKc_HER2 - cd05109
STKc_PCTAIRE3 - cd07871
PTKc_Trk - cd05049
PTKc_Ror - cd05048
PTKc_DDR - cd05051
PTK_CCK4 - cd05046
PTKc_EGFR - cd05108
PTKc_EGFR_like - cd05057
PTKc_Tie2 - cd05088
PTKc_DDR1 - cd05096
PTKc_DDR2 - cd05095
PTKc_TrkC - cd05094
PTKc_TrkB - cd05093
PTKc_DDR_like - cd05097
PTKc_Btk_Bmx - cd05113
PKc_MAPKK_Byr1_like - cd06620
PKc_MKK4 - cd06616
PTKc_TrkA - cd05092
PTKc_Tec_Rlk - cd05114
PTKc_Itk - cd05112
STKc_SLK_like - cd06611
PTKc_Musk - cd05050
PTKc_Tec_like - cd05059
PTKc_EphR - cd05033
PTKc_Jak_rpt2 - cd05038
PTKc_Ror2 - cd05091
PTK_Ryk - cd05043
PTKc_EphR_A2 - cd05063
PTKc_EphR_A10 - cd05064
PTKc_Jak2_Jak3_rpt2 - cd05081
PTKc_Ror1 - cd05090
PTKc_Tyk2_rpt2 - cd05080
PTKc_Jak1_rpt2 - cd05079
PTKc_EphR_B - cd05065
PTKc_EphR_A - cd05066
STKc_BUR1 - cd07866
STKc_PCTAIRE1 - cd07873
STKc_CDK2_3 - cd07860
STKc_GRK4 - cd05631
STKc_MAP4K3_like - cd06613
STKc_Pho85 - cd07836
STKc_PCTAIRE_like - cd07844
PTKc_Tie1 - cd05089
STKc_Nek6 - cd08228
STKc_Nek6_Nek7 - cd08224
STKc_Nek7 - cd08229
STKc_MEKK2 - cd06652
STKc_STK25-YSK1 - cd06642
STKc_MST3 - cd06641
STKc_MEKK3_like_1 - cd06653
STKc_MST4 - cd06640
SPS1 - COG0515
PKc_MAPKK_plant_like - cd06623
STKc_ERK1_2_like - cd07849
STKc_CDK6 - cd07862
STKc_CDKL1_4 - cd07847
STKc_CDK8_like - cd07842
STKc_PRKX_like - cd05612
STKc_phototropin_lik - cd05574
STKc_PKA - cd05580
PTK_Jak_rpt1 - cd05037
PTKc_ALK_LTK - cd05036
PTK_Jak1_rpt1 - cd05077
STKc_ROCK_NDR_like - cd05573
PKc_MAPKK_PBS2_like - cd06622
PKc_MAPKK_Pek1_like - cd06621
PKc_MAPKK - cd06605
PKc_MKK3_6 - cd06617
STKc_OSR1_SPAK - cd06610
STKc_MST3_like - cd06609
PKc_MEK - cd06615
STKc_Nek1 - cd08218
STKc_Nek - cd08215
STKc_CDK1_euk - cd07861
STKc_Nek3 - cd08219
STKc_MPK1 - cd07857
STKc_CDK4 - cd07863
STKc_Nek5 - cd08225
STKc_CNK2-like - cd08530
STKc_MAPK - cd07834
STKc_FA2-like - cd08529
STKc_Nek10 - cd08528
STKc_Nek4 - cd08223
STKc_Nek11 - cd08222
STKc_CDK7 - cd07841
STKc_Yank1 - cd05578
STKc_cPKC - cd05587
STKc_GRK4_like - cd05605
STKc_CCRK - cd07832
PTKc_RET - cd05045
PKc_STE - cd05122
STKc_CMGC - cd05118
STKc_GRK6 - cd05630
STKc_cPKC_alpha - cd05615
STKc_GRK5 - cd05632
STKc_MEKK1 - cd06630
STKc_YSK4 - cd06631
STKc_MEKK3 - cd06651
STKc_MAPKKK_Byr2_lik - cd06628
STKc_Cdc7_like - cd06627
STKc_MSK_N - cd05583
STKc_MAPKKK - cd06606
STYKc - smart00221
TyrKc - smart00219
Pkinase - pfam00069
STKc_MAPK4_6 - cd07854
Pkinase_Tyr - pfam07714
PTKc_Axl_like - cd05035
PTKc_Axl - cd05075
PTKc_Tyro3 - cd05074
STKc_PKN - cd05589
STKc_CDK_like - cd07829
STKc_CDK1_like - cd07835
STKc_MAK_like - cd07830
STKc_CDK4_6_like - cd07838
STKc_MEKK3_like - cd06625
STKc_CDKL2_3 - cd07846
STKc_Sty1_Hog1 - cd07856
STKc_CDKL - cd07833
STKc_myosinIII_like - cd06608
PK_STRAD - cd08216
STKc_MEKK4 - cd06626
STKc_PDK1 - cd05581
STKc_MEKK1_plant - cd06632
STKc_MAPKKK_Bck1_lik - cd06629
STKc_nPKC_delta - cd05620
STKc_nPKC_theta_delt - cd05592
STKc_nPKC_theta - cd05619
STKc_MOK - cd07831
STKc_CDK9_like - cd07840
STKc_PKC - cd05570
STKc_Nek2 - cd08217
STKc_CDK5 - cd07839
PTKc_Ack_like - cd05040
PTKc - cd00192
PTKc_Fes_like - cd05041
PTKc_Aatyk - cd05042
PTKc_Syk - cd05116
PTKc_c-ros - cd05044
PTKc_Met_Ron - cd05058
PTKc_Syk_like - cd05060
PTKc_Aatyk1_Aatyk3 - cd05087
PTKc_Zap-70 - cd05115
PTKc_Aatyk2 - cd05086
PTKc_Fer - cd05085
PTK_Jak2_Jak3_rpt1 - cd05078
PTKc_Fes - cd05084
PTKc_Tie - cd05047
STKc_CdkB_plant - cd07837
STKc_Nek9 - cd08221
STKc_Nek8 - cd08220
STKc_MAST_like - cd05579
STKc_cGK_PKG - cd05572
STKc_AGC - cd05123
PKc - cd00180
STKc_CDC2L1 - cd07843
STKc_GRK - cd05577
STKc_GRK1 - cd05608
STKc_NAK1_like - cd06917
STKc_MST1_2 - cd06612
S_TKc - smart00220
KIND - smart00750


Swiss-Prot Protein: P42679
Identical to: NP_647612
   Default View:





























































































































































































































Domains found on the Protein

Domain ↕CD Accession ↕E-Value ↕Start ↕End ↕
SH3cd001745e-0852107
PTKc_VEGFRcd050548.4e-30116485
PTKc_Kitcd051042.4e-21120482
PTKc_PDGFR_betacd051073.5e-10120483
SH2cd001731.2e-31121211
PTKc_PDGFR_alphacd051051.1e-14196484
PTKc_CSF-1Rcd051061e-27198483
PTKc_PDGFRcd050555.3e-21208482
STKc_PAK6cd066597.7e-07212501
PKc_MKK5cd066190.00058215503
PTK_Tyk2_rpt1cd050768.3e-07218479
STKc_PAK5cd066581.3e-05218499
STKc_PAK1cd066542.3e-06218500
PTKc_FGFR1cd050983.3e-58219495
STKc_PAKcd066147.5e-13219482
STKc_PAK_Icd066471.2e-05219498
STKc_PAK2cd066554.4e-06219501
STKc_PAK3cd066561.3e-06219502
PTKc_FGFR2cd051011.5e-54220489
STKc_TAOcd066070.00059220505
STKc_PAK_IIcd066481.9e-08220495
STKc_TAO2cd066340.00022220506
STKc_PAK4cd066571.8e-05220501
STKc_p38gamma_MAPK12cd078800.00089220507
STKc_STK10_LOKcd066443.7e-06221491
PKc_MKK7cd066181.6e-05222494
STKc_MAP4K3cd066450.0001222479
STKc_MAP4K5cd066463.2e-05222479
STKc_CDK9cd078657.3e-06222471
STKc_myosinIIIAcd066380.001223480
STKc_PFTAIRE2cd078706.6e-06223502
PTKc_FGFR4cd050993.8e-56224503
PTKc_FGFR3cd051004.1e-49224506
STKc_ASKcd066242.5e-09226480
PTKc_VEGFR3cd051021.5e-32227485
PTKc_VEGFR2cd051039.6e-28227485
PTK_HER3cd051112.2e-45227492
STKc_CDK10cd078451.2e-06227452
PTKc_InsR_likecd050321.1e-58228480
PTKc_Src_likecd050341.1e-92228481
PTKc_Csk_likecd050393.8e-203228481
PTKc_Ablcd050524.9e-85228482
PTKc_FGFRcd050533.1e-68228483
PTKc_FAKcd050561e-68228486
PTKc_InsRcd050614.5e-48228491
PTKc_IGF-1Rcd050623.1e-43228480
PTKc_Lck_Blkcd050679.5e-76228481
PTKc_Yescd050691.9e-69228481
PTKc_Fyn_Yrkcd050701.5e-73228481
PTKc_Frk_likecd050687.1e-81228481
PTKc_Srccd050711.2e-71228483
PTKc_Lyncd050725.4e-70228481
PTKc_Hckcd050732.2e-74228481
PTKc_Cskcd050822.5e-126228481
PTKc_Chkcd050834.2e-204228481
PTKc_Srm_Brkcd051482.5e-79228481
STKc_CDK12cd078641.3e-06228502
PTK_CCK4cd050461.7e-36229480
PTKc_Rorcd050481.1e-45229482
PTKc_Trkcd050492.6e-54229480
PTKc_DDRcd050514.5e-28229480
PTKc_EGFR_likecd050574.7e-56229492
PTKc_Tie2cd050882.3e-46229496
PTKc_EGFRcd051081.4e-32229507
PTKc_HER2cd051092.2e-40229492
PTKc_HER4cd051103.4e-33229507
STKc_SLKcd066436.6e-06229489
STKc_PCTAIRE3cd078712.6e-05229505
PTKc_EphRcd050339.7e-74230482
PTKc_Jak_rpt2cd050381.7e-66230482
PTK_Rykcd050434.5e-22230482
PTKc_Muskcd050502e-49230480
PTKc_Tec_likecd050592.1e-83230479
PTKc_EphR_A2cd050631.9e-60230482
PTKc_EphR_A10cd050641.2e-58230482
PTKc_EphR_Bcd050658.3e-59230482
PTKc_EphR_Acd050661.2e-61230482
PTKc_Jak1_rpt2cd050793.8e-38230482
PTKc_Tyk2_rpt2cd050801.1e-37230483
PTKc_Jak2_Jak3_rpt2cd050813.8e-45230482
PTKc_Ror1cd050902.6e-43230481
PTKc_Ror2cd050912.2e-41230481
PTKc_TrkAcd050921.5e-43230488
PTKc_TrkBcd050933.2e-37230492
PTKc_TrkCcd050944e-17230492
PTKc_DDR2cd050951.2e-24230480
PTKc_DDR1cd050967.3e-21230480
PTKc_DDR_likecd050973.1e-32230480
PTKc_Itkcd051123.1e-74230479
PTKc_Btk_Bmxcd051131.1e-75230479
PTKc_Tec_Rlkcd051143.9e-69230479
STKc_SLK_likecd066113.8e-07230485
PKc_MKK4cd066164.6e-08230497
PKc_MAPKK_Byr1_likecd066200.00013230485
STKc_GRK4cd056310.00042231507
STKc_MAP4K3_likecd066132.1e-08231479
STKc_Pho85cd078363.3e-05231502
STKc_PCTAIRE_likecd078449.5e-07231502
STKc_CDK2_3cd078605.2e-06231502
STKc_BUR1cd078660.00033231471
STKc_PCTAIRE1cd078730.00073231503
PTKc_Tie1cd050892.4e-52232495
STKc_Nek6_Nek7cd082243.4e-08232484
STKc_Nek6cd082283.9e-07232484
STKc_Nek7cd082291.8e-08232484
PTKc_ALK_LTKcd050361.1e-70233480
PTK_Jak_rpt1cd050371.7e-12233479
PTK_Jak1_rpt1cd050771.2e-09233479
STKc_phototropin_likcd055740.00028233495
STKc_PKAcd055801.5e-06233504
STKc_ROCK_NDR_likecd055730.00031233502
STKc_PRKX_likecd056122.4e-06233507
PKc_MAPKKcd066052.3e-07233481
STKc_MST3_likecd066091.4e-09233487
PKc_MEKcd066151.3e-05233492
PKc_MKK3_6cd066171.3e-06233496
PKc_MAPKK_Pek1_likecd066214e-07233483
STKc_OSR1_SPAKcd066101.3e-11233480
PKc_MAPKK_PBS2_likecd066227.1e-06233507
PKc_MAPKK_plant_likecd066237.1e-12233477
STKc_MST4cd066406e-06233503
STKc_MST3cd066411.4e-06233503
STKc_STK25-YSK1cd066422.1e-06233485
STKc_MEKK2cd066520.00047233485
STKc_MEKK3_like_1cd066530.0001233484
STKc_CDK8_likecd078421.1e-05233471
STKc_CDKL1_4cd078470.00018233480
STKc_CDK6cd078622.6e-05233505
STKc_ERK1_2_likecd078490.00047233484
SPS1COG05155.8e-06233504
PTKc_RETcd050456.3e-43234485
STKc_CMGCcd051181.6e-09234472
PKc_STEcd051228.1e-14234471
STKc_Yank1cd055784.1e-06234472
STKc_cPKCcd055870.00051234503
STKc_GRK4_likecd056051.2e-06234507
STKc_cPKC_alphacd056150.00076234503
STKc_GRK6cd056300.00016234507
STKc_GRK5cd056320.00015234490
STKc_MSK_Ncd055831.6e-05234507
STKc_MAPKKKcd066061.8e-20234472
STKc_Cdc7_likecd066275e-13234474
STKc_MAPKKK_Byr2_likcd066284.4e-15234480
STKc_MEKK1cd066302.3e-07234480
STKc_YSK4cd066314.3e-08234478
STKc_MEKK3cd066512.9e-06234482
STKc_CCRKcd078321.4e-07234473
STKc_MAPKcd078345.5e-06234506
STKc_CDK7cd078416.6e-09234479
STKc_MPK1cd078570.0002234491
STKc_CDK1_eukcd078610.00088234504
STKc_CDK4cd078630.00017234502
STKc_Nekcd082151.4e-14234480
STKc_Nek1cd082183.7e-07234480
STKc_Nek3cd082193.6e-11234483
STKc_Nek11cd082226.4e-07234479
STKc_Nek4cd082231.5e-05234480
STKc_Nek5cd082251.3e-09234480
STKc_Nek10cd085281.5e-06234480
STKc_FA2-likecd085291.1e-09234480
STKc_CNK2-likecd085301.4e-08234479
PTKc_Axl_likecd050357e-58235482
PTKc_Tyro3cd050741.8e-52235482
PTKc_Axlcd050752.7e-47235482
STKc_PKNcd055890.00011235506
STKc_CDK_likecd078295e-11235472
STKc_MAK_likecd078301.1e-08235471
STKc_CDK1_likecd078354.8e-06235502
STKc_CDK4_6_likecd078385.2e-08235442
STKc_MAPK4_6cd078542.4e-05235495
STKc_myosinIII_likecd066089.4e-06236462
STKc_MEKK3_likecd066252e-09236480
STKc_CDKLcd078336.5e-07236472
STKc_CDKL2_3cd078468.2e-06236483
STKc_Sty1_Hog1cd078560.001236505
PK_STRADcd082160.00015236484
STKc_PDK1cd055817.2e-11237471
STKc_MEKK4cd066262.1e-09237472
STKc_MAPKKK_Bck1_likcd066295.9e-11238472
STKc_MEKK1_plantcd066321.1e-09238472
PTKccd001921.3e-113239479
PTKc_Ack_likecd050401.1e-68239480
PTKc_Fes_likecd050419.5e-92239480
PTKc_Aatykcd050425.7e-14239480
PTKc_c-roscd050441.8e-56239480
PTKc_Tiecd050476.4e-57239483
PTKc_Met_Roncd050588.4e-62239484
PTKc_Syk_likecd050601.1e-74239483
PTK_Jak2_Jak3_rpt1cd050782.8e-13239479
PTKc_Fescd050841.9e-77239480
PTKc_Fercd050851.3e-78239480
PTKc_Aatyk2cd050863e-10239484
PTKc_Aatyk1_Aatyk3cd050871.1e-18239480
PTKc_Zap-70cd051152.2e-54239483
PTKc_Sykcd051168.5e-59239483
STKc_PKCcd055701.7e-06239483
STKc_nPKC_theta_deltcd055926.7e-05239507
STKc_nPKC_deltacd056200.00082239507
STKc_nPKC_thetacd056199.6e-06239507
STKc_MOKcd078314.8e-05239476
STKc_CDK5cd078391.2e-05239505
STKc_CDK9_likecd078404.3e-08239472
STKc_Nek2cd082171.8e-07239480
STKc_CdkB_plantcd078373.4e-05240481
PKccd001805.1e-57241478
STKc_AGCcd051231.3e-07241473
STKc_cGK_PKGcd055726.1e-06241478
STKc_GRKcd055770.00019241489
STKc_GRK1cd056089.9e-05241506
STKc_MAST_likecd055794.8e-07241471
STKc_MST1_2cd066121.5e-09241472
STKc_NAK1_likecd069174.3e-08241494
STKc_CDC2L1cd078430.00013241471
STKc_Nek8cd082205.8e-07241479
STKc_Nek9cd082214.6e-07241480
SH2pfam000176.5e-32122196
Pkinasepfam000696.2e-30235478
SH3smart003262.3e-0949108
SH2smart002521.9e-30120202
Pkinase_Tyrpfam077141.6e-129235478
TyrKcsmart002196.3e-126235482
STYKcsmart002211.5e-48235471
S_TKcsmart002209.9e-40245482
KINDsmart007501.5e-05310484

Table of Mutations found on the Protein

Source ↕Mut_ID ↕Class ↕HGVS ↕Disease ↕
Swiss-ProtVAR_041679Polymorphismp.ALA354THRN/A
dbSNPrs35351680 Polymorphismp.ALA496THRN/A
Swiss-ProtVAR_041681Polymorphismp.ARG503GLNN/A



   |   1000 Hilltop Circle, Baltimore, MD 21250   |   Department of Biological Sciences   |   Phone: 410-455-2258