Home News About DMDM Database Statistics Research Publications Contact  

Results for the Protein: P42685
1169745
FRK

FRK_HUMAN RecName: Full=Tyrosine-protein kinase FRK; AltName: Full=FYN-related kinase; AltName: Full=Nuclear tyrosine protein kinase RAK; AltName: Full=Protein-tyrosine kinase 5
0
3
0
1
2
Tips:
 The Domains on the Default View are decided by the Domain's E-Value.

 Clicking a check box will display or hide the correlated domain.

 To view the Gene page, either click on the link to the left or the blue bar above the Protein's graphic.



Default View:

SH3 - smart00326
SH3_2 - pfam07653
SH3 - cd00174
SH3_1 - pfam00018
SH2 - smart00252
SH2 - cd00173
SH2 - pfam00017
PTKc_VEGFR - cd05054
PTKc_Kit - cd05104
PTKc_PDGFR_beta - cd05107
PTKc_CSF-1R - cd05106
PTKc_PDGFR_alpha - cd05105
PTKc_PDGFR - cd05055
STKc_TAO3 - cd06633
STKc_PAK6 - cd06659
STKc_TAO2 - cd06634
STKc_PAK_I - cd06647
STKc_PAK5 - cd06658
STKc_myosinIIIB - cd06639
STKc_myosinIIIA - cd06638
STKc_PAK_II - cd06648
STKc_MAPK4_6 - cd07854
STKc_TAO - cd06607
PTKc_FGFR2 - cd05101
PTKc_FGFR1 - cd05098
PTKc_FGFR4 - cd05099
STKc_TAO1 - cd06635
STKc_PAK1 - cd06654
STKc_PAK2 - cd06655
STKc_MAP4K4_6 - cd06636
STKc_PAK4 - cd06657
STKc_p38 - cd07851
PKc_MKK7 - cd06618
PTKc_FGFR3 - cd05100
STKc_STK10_LOK - cd06644
STKc_SLK - cd06643
STKc_CDK9 - cd07865
STKc_Sty1_Hog1 - cd07856
STKc_PAK - cd06614
STKc_ASK - cd06624
PTKc_FGFR - cd05053
PTKc_VEGFR2 - cd05103
PTKc_VEGFR3 - cd05102
PTKc_EGFR_like - cd05057
PTKc_Tie1 - cd05089
PTKc_Src_like - cd05034
PTKc_Csk - cd05082
PTKc_Srm_Brk - cd05148
PTKc_InsR_like - cd05032
PTKc_Hck - cd05073
STKc_CDK12 - cd07864
STKc_ERK1_2_like - cd07849
PTKc_Chk - cd05083
PTKc_InsR - cd05061
PTKc_IGF-1R - cd05062
PTKc_Lyn - cd05072
PTKc_Csk_like - cd05039
PTKc_ALK_LTK - cd05036
PTKc_FAK - cd05056
PTKc_Abl - cd05052
PTKc_Lck_Blk - cd05067
PTKc_Fyn_Yrk - cd05070
PTKc_Src - cd05071
PTKc_Yes - cd05069
PTKc_Frk_like - cd05068
PTKc_DDR1 - cd05096
PTKc_DDR_like - cd05097
PKc_MAPKK_Byr1_like - cd06620
STKc_MAP4K3 - cd06645
PTKc_DDR2 - cd05095
STKc_MAP4K5 - cd06646
STKc_TNIK - cd06637
PTKc_Musk - cd05050
PTKc_EphR_A10 - cd05064
PTKc_Ror - cd05048
PTK_CCK4 - cd05046
PTKc_TrkC - cd05094
PTKc_EphR_A2 - cd05063
PTKc_Trk - cd05049
PTKc_TrkA - cd05092
PTKc_DDR - cd05051
PTKc_Ror1 - cd05090
PTKc_TrkB - cd05093
PTKc_Ror2 - cd05091
PTKc_Btk_Bmx - cd05113
PTKc_Itk - cd05112
PTKc_Tec_Rlk - cd05114
PKc_MKK4 - cd06616
STKc_MAPK15 - cd07852
PTK_HER3 - cd05111
STKc_SLK_like - cd06611
PTKc_Tie2 - cd05088
PTKc_Tec_like - cd05059
PTKc_EphR_B - cd05065
PTK_Ryk - cd05043
PTKc_Jak_rpt2 - cd05038
PTKc_EphR - cd05033
PTKc_EphR_A - cd05066
PTKc_Jak1_rpt2 - cd05079
PTKc_HER2 - cd05109
PTKc_EGFR - cd05108
PTKc_Jak2_Jak3_rpt2 - cd05081
PTKc_Tyk2_rpt2 - cd05080
PTKc_HER4 - cd05110
STKc_PCTAIRE2 - cd07872
STKc_MAP4K3_like - cd06613
STKc_PFTAIRE2 - cd07870
STKc_PCTAIRE_like - cd07844
STKc_MST3 - cd06641
STKc_PCTAIRE1 - cd07873
STKc_MST4 - cd06640
STKc_STK25-YSK1 - cd06642
STKc_Nek11 - cd08222
STKc_MEKK3_like_1 - cd06653
STKc_MEKK2 - cd06652
STKc_Nek6_Nek7 - cd08224
STKc_CDC2L1 - cd07843
STKc_CDKL2_3 - cd07846
STKc_CDKL - cd07833
STKc_CdkB_plant - cd07837
STKc_CDKL1_4 - cd07847
STKc_Nek7 - cd08229
STKc_MEKK3_like - cd06625
SPS1 - COG0515
STKc_Nek6 - cd08228
STKc_PCTAIRE3 - cd07871
STKc_CDK6 - cd07862
STKc_CRIK - cd05601
PKc_MAPKK_plant_like - cd06623
PKc_MAPKK - cd06605
STKc_myosinIII_like - cd06608
STKc_PDK1 - cd05581
STKc_PKA - cd05580
STKc_ROCK_NDR_like - cd05573
STKc_phototropin_lik - cd05574
STKc_MST3_like - cd06609
STKc_PRKX_like - cd05612
PKc_MAPKK_Pek1_like - cd06621
PKc_MAPKK_PBS2_like - cd06622
STKc_OSR1_SPAK - cd06610
PKc_MKK3_6 - cd06617
PKc_MKK5 - cd06619
PKc_MEK - cd06615
STKc_MST1_2 - cd06612
STKc_Nek1 - cd08218
STKc_Nek - cd08215
STKc_BUR1 - cd07866
STKc_Nek3 - cd08219
STKc_CDK4 - cd07863
STKc_Nek10 - cd08528
STKc_CDK2_3 - cd07860
STKc_Nek5 - cd08225
STKc_Nek4 - cd08223
STKc_Nek8 - cd08220
STKc_CDK1_euk - cd07861
STKc_MSK_N - cd05583
PTKc_RET - cd05045
STKc_GRK4_like - cd05605
STKc_cPKC_alpha - cd05615
STKc_GRK5 - cd05632
STKc_GRK6 - cd05630
STKc_MAPKKK - cd06606
STKc_Cdc7_like - cd06627
STKc_NLK - cd07853
STKc_MPK1 - cd07857
STKc_CDK8_like - cd07842
STKc_MAPK - cd07834
STKc_MEKK3 - cd06651
STKc_Pho85 - cd07836
STKc_CDK5 - cd07839
Pkinase - pfam00069
Pkinase_Tyr - pfam07714
STKc_PKN - cd05589
PTKc_Tyro3 - cd05074
PTKc_Axl_like - cd05035
TyrKc - smart00219
PTKc_Axl - cd05075
STKc_CDK1_like - cd07835
STYKc - smart00221
STKc_Nek2 - cd08217
STKc_CNK2-like - cd08530
STKc_FA2-like - cd08529
PK_STRAD - cd08216
STKc_CCRK - cd07832
STKc_NAK1_like - cd06917
STKc_MEKK4 - cd06626
STKc_CDK_like - cd07829
STKc_MAK_like - cd07830
STKc_CDK7 - cd07841
STKc_MOK - cd07831
STKc_Yank1 - cd05578
STKc_MAPKKK_Byr2_lik - cd06628
STKc_CDK9_like - cd07840
PKc_STE - cd05122
STKc_CDK4_6_like - cd07838
STKc_CMGC - cd05118
STKc_CDK10 - cd07845
STKc_RSK_N - cd05582
STKc_PKC - cd05570
PTKc_Syk - cd05116
PTKc_Aatyk1_Aatyk3 - cd05087
STKc_MEKK1 - cd06630
STKc_MEKK1_plant - cd06632
STKc_nPKC_theta - cd05619
STKc_nPKC_theta_delt - cd05592
PTKc_c-ros - cd05044
PTKc_Aatyk - cd05042
PTKc_Fes_like - cd05041
PTKc_Aatyk2 - cd05086
PTKc_Ack_like - cd05040
PTKc_Met_Ron - cd05058
PTKc_Tie - cd05047
PTK_Jak_rpt1 - cd05037
PTKc - cd00192
PTKc_Fes - cd05084
PTKc_Fer - cd05085
PTK_Jak2_Jak3_rpt1 - cd05078
PTK_Jak1_rpt1 - cd05077
PTKc_Syk_like - cd05060
PTK_Tyk2_rpt1 - cd05076
PTKc_Zap-70 - cd05115
STKc_GRK1 - cd05608
STKc_AGC - cd05123
PKc - cd00180
STKc_cGK_PKG - cd05572
STKc_GRK - cd05577
STKc_Nek9 - cd08221
STKc_YSK4 - cd06631
STKc_MAST_like - cd05579
STKc_MAPKKK_Bck1_lik - cd06629
S_TKc - smart00220


Swiss-Prot Protein: P42685
Identical to: NP_002022
   Default View:


































































































































































































































Domains found on the Protein

Domain ↕CD Accession ↕E-Value ↕Start ↕End ↕
SH3cd001743.9e-1946107
SH2cd001732.2e-37115208
PTKc_VEGFRcd050542e-23127494
PTKc_PDGFR_betacd051071.5e-10193492
PTKc_Kitcd051046.2e-22193491
PTKc_CSF-1Rcd051065.5e-30206492
PTKc_PDGFRcd050552.7e-21211491
PTKc_PDGFR_alphacd051052.6e-16211493
STKc_TAO3cd066330.00063211504
STKc_PAK6cd066593.1e-05213497
STKc_TAO2cd066343.4e-06214505
STKc_PAK_Icd066470.00023214505
STKc_PAK5cd066580.00042215505
STKc_myosinIIIBcd066390.00064216493
STKc_myosinIIIAcd066383.7e-05217492
STKc_PAK_IIcd066481.8e-06217501
STKc_MAPK4_6cd078540.00064217504
PTKc_FGFR1cd050985.7e-53218498
PTKc_FGFR2cd051011.1e-48218499
STKc_TAOcd066071.9e-05218504
PTKc_FGFR4cd050992.6e-57219500
STKc_TAO1cd066350.00014220504
STKc_MAP4K4_6cd066360.00013220492
STKc_PAK1cd066540.00088220502
STKc_PAK2cd066550.00078220505
STKc_PAK4cd066570.0009220505
PTKc_FGFR3cd051005.7e-42221504
PKc_MKK7cd066186.9e-08221505
STKc_STK10_LOKcd066444.3e-06221504
STKc_SLKcd066436.2e-06221502
STKc_p38cd078514e-05221505
STKc_CDK9cd078651.5e-06222491
STKc_Sty1_Hog1cd078560.00018223499
STKc_PAKcd066149e-14224504
PTKc_FGFRcd050532.7e-69225492
STKc_ASKcd066244.1e-07225492
PTKc_EGFR_likecd050572.8e-65226501
PTKc_VEGFR3cd051021.6e-25226494
PTKc_VEGFR2cd051032.2e-21226494
PTKc_InsR_likecd050322e-73227489
PTKc_Src_likecd050346.8e-213227490
PTKc_ALK_LTKcd050361.6e-61227489
PTKc_Csk_likecd050396.4e-85227490
PTKc_Ablcd050524.7e-114227491
PTKc_InsRcd050612.3e-55227496
PTKc_IGF-1Rcd050626.9e-51227489
PTKc_FAKcd050561.7e-83227495
PTKc_Lck_Blkcd050671.3e-126227490
PTKc_Frk_likecd050681.4e-185227490
PTKc_Yescd050694.3e-117227490
PTKc_Fyn_Yrkcd050703.8e-127227490
PTKc_Srccd050712.8e-124227492
PTKc_Lyncd050722.4e-129227490
PTKc_Hckcd050731.5e-126227490
PTKc_Cskcd050821.7e-75227490
PTKc_Chkcd050831.5e-75227490
PTKc_Tie1cd050891.2e-41227505
PTKc_Srm_Brkcd051481.4e-146227490
STKc_ERK1_2_likecd078494.3e-05227502
STKc_CDK12cd078642.3e-07227504
PTK_CCK4cd050463.2e-41228489
PTKc_Rorcd050486.7e-61228490
PTKc_Trkcd050492.7e-53228489
PTKc_Muskcd050501.5e-62228489
PTKc_EphR_A10cd050641.4e-60228491
PTKc_EphR_A2cd050634.1e-73228491
PTKc_DDRcd050517.8e-46228489
PTKc_Ror2cd050913.1e-47228490
PTKc_Ror1cd050901.2e-47228490
PTKc_TrkAcd050924.8e-55228489
PTKc_TrkBcd050938.7e-55228499
PTKc_TrkCcd050947.6e-39228499
PTKc_DDR2cd050953.5e-55228489
PTKc_DDR1cd050961.5e-40228489
PTKc_DDR_likecd050973.1e-53228489
PKc_MAPKK_Byr1_likecd066201.1e-07228504
STKc_TNIKcd066371.2e-05228492
STKc_MAP4K3cd066452.2e-06228491
STKc_MAP4K5cd066461.1e-06228491
PTKc_EphRcd050337e-102229491
PTKc_Jak_rpt2cd050382.3e-69229491
PTK_Rykcd050433.3e-34229494
PTKc_Tec_likecd050593.9e-104229488
PTKc_EphR_Bcd050651.8e-74229491
PTKc_EphR_Acd050668.5e-77229491
PTKc_Jak1_rpt2cd050795.6e-58229491
PTKc_Tyk2_rpt2cd050801.2e-42229492
PTKc_Jak2_Jak3_rpt2cd050817.8e-54229491
PTKc_Tie2cd050887.9e-38229505
PTKc_EGFRcd051085.8e-35229505
PTKc_HER2cd051095e-48229501
PTKc_HER4cd051103.5e-39229499
PTK_HER3cd051113.4e-39229501
PTKc_Itkcd051122.7e-90229488
PTKc_Btk_Bmxcd051131.7e-93229488
PTKc_Tec_Rlkcd051149.1e-90229488
STKc_SLK_likecd066113.4e-08229502
PKc_MKK4cd066168.5e-07229505
STKc_MAPK15cd078522.1e-06229500
STKc_MAP4K3_likecd066132e-11230491
STKc_MST4cd066409.5e-08230505
STKc_MST3cd066413.1e-08230505
STKc_PCTAIRE_likecd078449.7e-07230504
STKc_PFTAIRE2cd078701.1e-05230504
STKc_PCTAIRE1cd078730.00019230499
STKc_PCTAIRE2cd078723.3e-05230500
STKc_STK25-YSK1cd066421.2e-08231505
STKc_MEKK2cd066521.2e-05231489
STKc_MEKK3_like_1cd066531.5e-07231492
STKc_Nek6_Nek7cd082241.2e-09231492
STKc_Nek11cd082221.7e-09231488
STKc_ROCK_NDR_likecd055738.6e-05232505
STKc_phototropin_likcd055744.1e-05232500
STKc_PKAcd055802e-06232501
STKc_PDK1cd055812.5e-12232491
STKc_CRIKcd056010.00054232504
STKc_PRKX_likecd056120.00014232502
PKc_MAPKKcd066052.3e-10232493
STKc_myosinIII_likecd066081.3e-06232483
STKc_MST3_likecd066092e-11232498
STKc_OSR1_SPAKcd066102e-11232492
STKc_MST1_2cd066123.1e-11232492
PKc_MEKcd066154.3e-06232504
PKc_MKK3_6cd066171.7e-07232505
PKc_MKK5cd066190.00012232505
PKc_MAPKK_Pek1_likecd066211.6e-07232505
PKc_MAPKK_PBS2_likecd066222.1e-06232505
PKc_MAPKK_plant_likecd066232.5e-12232495
STKc_MEKK3_likecd066252.5e-11232492
STKc_CdkB_plantcd078372.3e-08232492
STKc_CDKLcd078337.5e-07232491
STKc_CDC2L1cd078432.7e-06232491
STKc_CDKL2_3cd078464.7e-07232491
STKc_CDKL1_4cd078476.2e-07232491
STKc_CDK6cd078620.00025232505
STKc_PCTAIRE3cd078711.6e-06232502
STKc_Nek6cd082288.5e-08232493
STKc_Nek7cd082292.1e-10232493
SPS1COG05154.1e-14232505
PTKc_RETcd050457.6e-52233494
STKc_MSK_Ncd055833.3e-05233499
STKc_GRK4_likecd056052.7e-06233495
STKc_cPKC_alphacd056150.00058233505
STKc_GRK6cd056300.00038233495
STKc_GRK5cd056320.00016233495
STKc_MAPKKKcd066063.8e-20233492
STKc_Cdc7_likecd066273.3e-17233486
STKc_MEKK3cd066515e-08233490
STKc_Pho85cd078361.1e-06233503
STKc_CDK5cd078393.2e-06233503
STKc_MAPKcd078341e-07233505
STKc_CDK8_likecd078420.00044233491
STKc_NLKcd078530.00073233503
STKc_MPK1cd078575.5e-06233504
STKc_CDK2_3cd078603.4e-06233504
STKc_CDK1_eukcd078615.5e-06233503
STKc_CDK4cd078630.00019233504
STKc_BUR1cd078662.4e-07233480
STKc_Nekcd082152.1e-15233492
STKc_Nek1cd082182e-09233488
STKc_Nek3cd082193.8e-09233487
STKc_Nek8cd082202.4e-05233492
STKc_Nek4cd082232.9e-07233491
STKc_Nek5cd082252.3e-06233487
STKc_Nek10cd085281.7e-07233489
PTKc_Axl_likecd050351.7e-63234491
PTKc_Tyro3cd050741.3e-58234491
PTKc_Axlcd050759.9e-55234491
STKc_PKNcd055897.2e-05234505
STKc_CDK1_likecd078351.5e-07234504
STKc_CMGCcd051181.8e-12235491
PKc_STEcd051227.4e-15235491
STKc_Yank1cd055781.3e-09235491
STKc_MEKK4cd066263.4e-10235492
STKc_MAPKKK_Byr2_likcd066283.2e-17235492
STKc_NAK1_likecd069177.7e-11235498
STKc_CDK_likecd078295.3e-14235491
STKc_MAK_likecd078308.4e-11235491
STKc_MOKcd078314.3e-05235491
STKc_CCRKcd078322e-07235487
STKc_CDK4_6_likecd078382.4e-05235491
STKc_CDK9_likecd078401.3e-10235491
STKc_CDK7cd078417.3e-10235504
PK_STRADcd082160.0004235493
STKc_Nek2cd082178.2e-08235492
STKc_CNK2-likecd085308e-08235483
STKc_FA2-likecd085292.3e-09235487
STKc_RSK_Ncd055820.00031237504
STKc_CDK10cd078453.5e-07237481
PTKccd001928.1e-131238488
PTK_Jak_rpt1cd050371.4e-12238488
PTKc_Fes_likecd050412.3e-88238489
PTKc_Aatykcd050421.7e-15238490
PTKc_c-roscd050441.7e-68238489
PTKc_Ack_likecd050403.1e-83238489
PTKc_Tiecd050478.5e-49238492
PTKc_Met_Roncd050581.2e-62238493
PTKc_Syk_likecd050605.5e-84238492
PTK_Tyk2_rpt1cd050765.9e-08238488
PTK_Jak1_rpt1cd050776.9e-10238488
PTK_Jak2_Jak3_rpt1cd050781.3e-13238488
PTKc_Fescd050843.3e-74238489
PTKc_Fercd050852.3e-75238489
PTKc_Aatyk2cd050868.9e-16238490
PTKc_Aatyk1_Aatyk3cd050871.1e-25238489
PTKc_Sykcd051169.1e-68238492
STKc_PKCcd055707.1e-07238498
STKc_nPKC_theta_deltcd055920.00052238503
STKc_nPKC_thetacd056194.2e-05238505
STKc_MEKK1cd066305.6e-07238484
STKc_MEKK1_plantcd066325.3e-12238483
PTKc_Zap-70cd051152.1e-61239492
PKccd001803.9e-65240487
STKc_AGCcd051231.6e-09240485
STKc_cGK_PKGcd055724.2e-09240487
STKc_GRKcd055771.7e-05240494
STKc_MAST_likecd055793.5e-07240485
STKc_GRK1cd056083.7e-05240499
STKc_YSK4cd066311.7e-09240492
STKc_Nek9cd082211.3e-06240487
STKc_MAPKKK_Bck1_likcd066291.4e-10241492
SH3_1pfam000183e-1448102
SH2pfam000175.1e-38116193
Pkinasepfam000691.6e-45234487
SH3smart003266.6e-2243108
SH3_2pfam076538.2e-1046107
SH2smart002526.1e-35114199
Pkinase_Tyrpfam077141.1e-144234487
TyrKcsmart002194e-135234487
STYKcsmart002213.4e-61234489
S_TKcsmart002208e-53244491

Table of Mutations found on the Protein

Source ↕Mut_ID ↕Class ↕HGVS ↕Disease ↕
dbSNPrs3756772 Polymorphismp.GLY122ARGN/A
Swiss-ProtVAR_041702Polymorphismp.ILE100VALN/A
Swiss-ProtVAR_041703Polymorphismp.SER133LEUN/A



   |   1000 Hilltop Circle, Baltimore, MD 21250   |   Department of Biological Sciences   |   Phone: 410-455-2258