Results for the protein: P16455

Results for the Protein: P16455

127069

4255

MGMT

NCBI, UniProt

MGMT_HUMAN RecName: Full=Methylated-DNA--protein-cysteine methyltransferase; AltName: Full=6-O-methylguanine-DNA methyltransferase; Short=MGMT; AltName: Full=O-6-methylguanine-DNA-alkyltransferase

			0 10 0 0 10

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Default View: Ada - COG0350 Methyltransf_1N - pfam02870 COG3695 - COG3695 DNA_binding_1 - pfam01035 ATase - cd06445	Swiss-Prot Protein: P16455 Default View:

Domains found on the Protein

Domain ↕	CD Accession ↕	E-Value ↕	Start ↕	End ↕
ATase	cd06445	2.4e-42	94	173
Methyltransf_1N	pfam02870	2.9e-30	6	90
COG3695	COG3695	9.2e-09	86	188
DNA_binding_1	pfam01035	5.1e-43	92	177

Table of Mutations found on the Protein

Source ↕	Mut_ID ↕	Class ↕	HGVS ↕	Disease ↕
Swiss-Prot	VAR_014754	Polymorphism	p.GLU166ASP	N/A
Swiss-Prot	VAR_014750	Polymorphism	p.GLU30LYS	N/A
Swiss-Prot	VAR_014753	Polymorphism	p.GLY160ARG	N/A
Swiss-Prot	VAR_056130	Polymorphism	p.ILE112VAL	N/A
Swiss-Prot	VAR_014752	Polymorphism	p.ILE143VAL	N/A
Swiss-Prot	VAR_056129	Polymorphism	p.LEU53PHE	N/A
Swiss-Prot	VAR_014751	Polymorphism	p.LEU84PHE	N/A
Swiss-Prot	VAR_014755	Polymorphism	p.LYS178ARG	N/A
Swiss-Prot	VAR_029112	Polymorphism	p.PRO58SER	N/A
Swiss-Prot	VAR_020354	Polymorphism	p.TRP65CYS	N/A

Please Cite: Peterson, T.A., Adadey, A., Santana-Cruz ,I., Sun, Y., Winder A, Kann, M.G., (2010) DMDM: Domain Mapping of Disease Mutations. Bioinformatics 26 (19), 2458-2459.

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