Results for the protein: Q9Y6E0

Results for the Protein: Q9Y6E0

13626607

8428

STK24

NCBI, UniProt

STK24_HUMAN RecName: Full=Serine/threonine-protein kinase 24; AltName: Full=Mammalian STE20-like protein kinase 3; Short=MST-3; AltName: Full=STE20-like kinase MST3; Contains: RecName: Full=Serine/threonine-protein kinase 24 36 kDa subunit; AltName: Full=Mammalian STE20-like protein kinase 3 N-terminal; Short=MST3/N; Contains: RecName: Full=Serine/threonine-protein kinase 24 12 kDa subunit; AltName: Full=Mammalian STE20-like protein kinase 3 C-terminal; Short=MST3/C

			0 2 0 0 2

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Swiss-Prot Protein: Q9Y6E0

Identical to: NP_003567

Default View:

Domains found on the Protein

Domain ↕	CD Accession ↕	E-Value ↕	Start ↕	End ↕
STKc_ROCK	cd05596	4.8e-07	5	373
STKc_ROCK2	cd05621	4.4e-09	5	373
STKc_ROCK1	cd05622	5.5e-07	5	374
STKc_myosinIIIB	cd06639	3.4e-66	7	287
STKc_p38beta_MAPK11	cd07878	1.7e-05	7	345
STKc_PAK5	cd06658	1.2e-52	9	304
STKc_PAK6	cd06659	8.2e-54	10	310
STKc_JNK1	cd07875	0.00099	10	350
STKc_TAO1	cd06635	3.3e-69	11	312
STKc_PAK1	cd06654	3.5e-71	11	310
STKc_PAK2	cd06655	2e-68	11	310
STKc_PAK3	cd06656	9.4e-73	11	312
STKc_PAK4	cd06657	8.6e-50	11	307
STKc_TAO	cd06607	2.2e-78	13	312
STKc_JNK3	cd07874	0.00063	13	374
PTKc_PDGFR	cd05055	5.5e-05	15	290
STKc_TAO3	cd06633	3.3e-69	15	327
STKc_PAK	cd06614	3.5e-118	16	300
PTK_Tyk2_rpt1	cd05076	0.00067	17	285
STKc_JNK	cd07850	1.3e-05	17	345
STKc_p38alpha_MAPK14	cd07877	2.2e-05	17	356
STKc_myosinIIIA	cd06638	1.9e-76	19	286
STKc_TAO2	cd06634	6.4e-65	21	313
STKc_MAP4K4_6	cd06636	6.4e-81	21	286
STKc_PAK_II	cd06648	9.7e-67	21	300
STKc_p38gamma_MAPK12	cd07880	2.1e-07	21	346
PTKc_FGFR1	cd05098	1.6e-06	23	297
STKc_CDK9	cd07865	4.9e-11	23	286
STKc_BUR1	cd07866	6.7e-12	23	286
PKc_MKK7	cd06618	1.6e-29	24	302
STKc_STK10_LOK	cd06644	5.1e-78	24	310
STKc_p38delta_MAPK13	cd07879	0.00028	24	356
STKc_CDK12	cd07864	1.2e-12	24	286
PTKc_FGFR2	cd05101	1.4e-07	25	294
STKc_p38	cd07851	1.5e-08	25	319
STKc_ASK	cd06624	1.4e-45	26	286
STKc_MAP4K5	cd06646	9.6e-86	26	285
STKc_PAK_I	cd06647	1.2e-77	26	308
PKc_MEK2	cd06649	1.6e-17	27	313
PKc_MEK1	cd06650	8.1e-21	27	324
PTKc_Abl	cd05052	3e-15	28	285
PTKc_FGFR	cd05053	3.1e-09	28	287
PTKc_EGFR_like	cd05057	9.6e-10	28	299
PTKc_FGFR4	cd05099	2.7e-09	28	309
PTKc_EGFR	cd05108	9.7e-09	28	340
PTKc_FGFR3	cd05100	7.8e-07	28	325
PTKc_HER2	cd05109	4.2e-10	28	301
PTKc_HER4	cd05110	5e-07	28	325
PTK_HER3	cd05111	4.3e-11	28	299
PTK_Ryk	cd05043	3.7e-05	28	266
STKc_myosinIII_like	cd06608	3.4e-108	28	286
PTKc_ALK_LTK	cd05036	3.7e-12	29	286
PTKc_EphR_A2	cd05063	4e-10	29	286
PTKc_TrkA	cd05092	3.6e-07	29	287
PTKc_TrkB	cd05093	1.3e-07	29	297
PTKc_TrkC	cd05094	8.8e-05	29	297
PTKc_VEGFR2	cd05103	2.4e-05	29	291
STKc_TNIK	cd06637	1.2e-82	29	286
STKc_MAP4K3	cd06645	1.6e-85	29	285
STKc_CDK10	cd07845	2.3e-12	29	296
STKc_PFTAIRE1	cd07869	1.4e-06	29	333
PTKc_EphR	cd05033	4.1e-11	30	286
PTK_CCK4	cd05046	4.2e-08	30	289
PTKc_Tec_like	cd05059	6.1e-14	30	285
PTKc_Csk	cd05082	1.2e-07	30	284
PTKc_Btk_Bmx	cd05113	8.2e-18	30	285
PTKc_Tec_Rlk	cd05114	3.5e-22	30	285
PTKc_Itk	cd05112	2.8e-17	30	285
STKc_SLK_like	cd06611	6.1e-98	30	302
STKc_SLK	cd06643	2.5e-74	30	305
STKc_ERK1_2_like	cd07849	8.3e-07	30	311
STKc_MAPK4_6	cd07854	4.2e-07	30	319
STKc_TEY_MAPK_plant	cd07858	2.3e-07	30	346
STKc_PFTAIRE2	cd07870	5.6e-09	30	304
PTKc_EphR_A10	cd05064	6.1e-08	31	290
PKc_MAPKK_Byr1_like	cd06620	5.5e-20	31	296
STKc_MST4	cd06640	3e-231	31	307
STKc_MST3	cd06641	3.1e-254	31	307
STKc_STK25-YSK1	cd06642	1.1e-229	31	307
STKc_PCTAIRE_like	cd07844	5.6e-16	31	320
STKc_ERK5	cd07855	5.4e-08	31	318
STKc_Sty1_Hog1	cd07856	9.2e-08	31	358
PTKc_InsR_like	cd05032	3.8e-14	32	289
PTKc_Src_like	cd05034	7.3e-14	32	286
PTKc_Jak_rpt2	cd05038	1.3e-13	32	288
PTKc_Csk_like	cd05039	9.3e-11	32	287
PTKc_Trk	cd05049	1.7e-08	32	289
PTKc_Musk	cd05050	4.5e-11	32	288
PTKc_InsR	cd05061	1e-09	32	300
PTKc_IGF-1R	cd05062	1.4e-09	32	283
PTKc_Lck_Blk	cd05067	5.6e-12	32	290
PTKc_Frk_like	cd05068	3.3e-23	32	288
PTKc_Yes	cd05069	2.5e-10	32	284
PTKc_Fyn_Yrk	cd05070	1.7e-08	32	289
PTKc_Src	cd05071	5.5e-09	32	286
PTKc_Lyn	cd05072	5.7e-10	32	285
PTKc_Hck	cd05073	2.6e-09	32	285
PTKc_Ror1	cd05090	7.3e-07	32	290
PTKc_DDR2	cd05095	9e-07	32	288
PTKc_DDR_like	cd05097	1.2e-05	32	288
PTKc_DDR1	cd05096	5.6e-05	32	288
PTKc_Srm_Brk	cd05148	1.8e-09	32	286
STKc_MST1_2	cd06612	8.1e-146	32	286
STKc_MAP4K3_like	cd06613	6.4e-141	32	285
STKc_MEKK3_like_1	cd06653	1.9e-34	32	286
PTKc_Ror	cd05048	7.8e-08	33	287
PTKc_DDR	cd05051	2.9e-07	33	288
PTKc_EphR_B	cd05065	9.2e-11	33	286
PTKc_EphR_A	cd05066	1.3e-10	33	286
PTKc_Jak1_rpt2	cd05079	4e-11	33	307
PTKc_Jak2_Jak3_rpt2	cd05081	2.8e-11	33	288
PKc_MAPKK_PBS2_like	cd06622	1.2e-45	33	345
STKc_MAPK15	cd07852	2.2e-11	33	319
PTKc_FAK	cd05056	4.5e-13	34	292
PTKc_Chk	cd05083	6.7e-09	34	284
PTKc_Tie1	cd05089	1.5e-07	34	309
PTKc_Ror2	cd05091	4.7e-05	34	290
STKc_phototropin_lik	cd05574	6.1e-12	34	304
STKc_ROCK_NDR_like	cd05573	1.2e-15	34	342
STKc_PKA	cd05580	5.7e-14	34	320
STKc_PDK1	cd05581	2.5e-24	34	286
STKc_DMPK_like	cd05597	2.7e-09	34	342
STKc_LATS	cd05598	2.1e-09	34	345
STKc_NDR_like	cd05599	6.8e-09	34	345
STKc_Sid2p_Dbf2p	cd05600	4e-10	34	343
STKc_MAST	cd05609	3.7e-10	34	319
STKc_PRKX_like	cd05612	1e-10	34	304
STKc_MRCK_alpha	cd05623	2.6e-08	34	343
STKc_MRCK_beta	cd05624	2.6e-07	34	342
STKc_LATS1	cd05625	1.9e-05	34	345
STKc_LATS2	cd05626	2e-05	34	363
STKc_NDR2	cd05627	4.7e-07	34	372
STKc_NDR1	cd05628	8e-10	34	350
STKc_NDR_like_fungal	cd05629	4.3e-06	34	345
STKc_MST3_like	cd06609	1.4e-225	34	307
PKc_MEK	cd06615	1e-32	34	300
PKc_MAPKK	cd06605	6.6e-59	34	291
PKc_MKK3_6	cd06617	1e-19	34	301
PKc_MKK5	cd06619	7.1e-43	34	308
PKc_MAPKK_Pek1_like	cd06621	5.7e-35	34	300
PKc_MAPKK_plant_like	cd06623	2.2e-74	34	292
STKc_NAK1_like	cd06917	3.8e-131	34	304
STKc_CDKL	cd07833	1.3e-15	34	286
STKc_CdkB_plant	cd07837	2.7e-12	34	287
STKc_CDC2L1	cd07843	7.7e-13	34	286
STKc_CDKL2_3	cd07846	9.5e-13	34	286
STKc_CDKL1_4	cd07847	3.7e-24	34	317
STKc_CDKL5	cd07848	6.5e-06	34	286
STKc_CDK6	cd07862	1.2e-07	34	311
STKc_PCTAIRE3	cd07871	2.8e-10	34	304
STKc_PCTAIRE2	cd07872	7e-10	34	306
STKc_PCTAIRE1	cd07873	2.4e-08	34	308
STKc_Nek6_Nek7	cd08224	3.8e-31	34	295
PK_STRAD_beta	cd08226	1.9e-08	34	301
SPS1	COG0515	1.1e-67	34	433
PKc_STE	cd05122	1.9e-159	35	285
STKc_GRK4_like	cd05605	8.1e-11	35	319
STKc_GRK6	cd05630	6.7e-07	35	307
STKc_GRK4	cd05631	3e-07	35	308
STKc_GRK5	cd05632	3.4e-07	35	308
STKc_MAPKKK	cd06606	2.5e-90	35	286
STKc_Cdc7_like	cd06627	7.8e-96	35	286
STKc_MAPKKK_Byr2_lik	cd06628	2.9e-59	35	286
STKc_MEKK1	cd06630	2.8e-18	35	286
STKc_YSK4	cd06631	1.4e-42	35	286
STKc_CCRK	cd07832	6.9e-16	35	287
STKc_MAPK	cd07834	9.9e-12	35	313
STKc_Pho85	cd07836	1.7e-16	35	317
STKc_CDK5	cd07839	1.3e-10	35	304
STKc_CDK7	cd07841	7.8e-13	35	300
STKc_CDK8_like	cd07842	9.8e-09	35	286
STKc_NLK	cd07853	2.7e-06	35	390
STKc_MPK1	cd07857	1.5e-05	35	327
STKc_TDY_MAPK_plant	cd07859	2e-08	35	346
STKc_CDK2_3	cd07860	2e-17	35	304
STKc_CDK4	cd07863	4.2e-09	35	304
STKc_CDC2L6	cd07867	6e-06	35	317
STKc_CDK8	cd07868	1.4e-05	35	317
STKc_Nek	cd08215	1.9e-66	35	286
STKc_Nek2	cd08217	5.5e-23	35	286
STKc_Nek9	cd08221	5.8e-22	35	286
STKc_Nek4	cd08223	1.7e-28	35	286
STKc_Nek5	cd08225	1.5e-37	35	286
STKc_Nek10	cd08528	4.2e-16	35	289
STKc_CNK2-like	cd08530	5.5e-21	35	286
PTKc_Tyro3	cd05074	1.7e-07	36	288
PTKc_Axl	cd05075	4.7e-06	36	291
PTKc_Tyk2_rpt2	cd05080	1e-10	36	292
PTKc_Tie2	cd05088	1.2e-07	36	310
STKc_CMGC	cd05118	2.8e-17	36	286
STKc_Yank1	cd05578	1.2e-18	36	286
STKc_MSK_N	cd05583	3.1e-11	36	305
STKc_cPKC	cd05587	1.5e-17	36	353
STKc_PKN	cd05589	3.3e-10	36	352
STKc_CRIK	cd05601	8.8e-11	36	340
STKc_MSK1_N	cd05613	4.7e-08	36	305
STKc_MSK2_N	cd05614	1.3e-08	36	343
STKc_cPKC_alpha	cd05615	5e-10	36	353
STKc_cPKC_beta	cd05616	2.7e-08	36	356
PKc_MKK4	cd06616	1e-19	36	300
STKc_MEKK3	cd06651	1.2e-34	36	288
STKc_CDK_like	cd07829	1e-21	36	286
STKc_MAK_like	cd07830	1.5e-14	36	286
STKc_CDK1_like	cd07835	5.2e-15	36	304
STKc_MOK	cd07831	3.6e-10	36	286
STKc_CDK4_6_like	cd07838	6.3e-16	36	286
STKc_CDK9_like	cd07840	8.3e-17	36	286
STKc_CDK1_euk	cd07861	2.2e-17	36	304
STKc_Nek1	cd08218	3.9e-35	36	286
STKc_Nek3	cd08219	6.7e-29	36	286
STKc_Nek11	cd08222	3.2e-36	36	286
STKc_Nek6	cd08228	4.3e-23	36	289
STKc_Nek7	cd08229	9.3e-20	36	286
STKc_FA2-like	cd08529	1.1e-36	36	286
PTKc_Axl_like	cd05035	3.7e-07	37	287
PK_STRAD	cd08216	2.6e-17	37	298
PK_STRAD_alpha	cd08227	1.9e-09	37	382
PTKc_RET	cd05045	1.4e-08	38	289
STKc_PKB_gamma	cd05593	1.4e-10	38	360
STKc_PKB_alpha	cd05594	5.8e-13	38	357
STKc_PKB_beta	cd05595	8.5e-09	38	358
STKc_MEKK3_like	cd06625	2.4e-57	38	286
STKc_MEKK4	cd06626	4.1e-37	38	286
STKc_MAPKKK_Bck1_lik	cd06629	1e-21	38	286
STKc_MEKK1_plant	cd06632	4.5e-63	38	286
STKc_MEKK2	cd06652	3.9e-29	38	287
STKc_Nek8	cd08220	4.5e-29	38	286
STKc_RSK_N	cd05582	3.8e-12	39	341
STKc_p70S6K	cd05584	6.4e-13	39	344
STKc_Rim15_like	cd05611	2.7e-07	39	285
STKc_OSR1_SPAK	cd06610	8.3e-117	39	286
PTKc	cd00192	5.1e-35	40	285
PTK_Jak_rpt1	cd05037	2e-06	40	291
PTKc_Ack_like	cd05040	5.6e-14	40	282
PTKc_Fes_like	cd05041	9.3e-15	40	286
PTKc_Aatyk	cd05042	3.1e-07	40	283
PTKc_c-ros	cd05044	7.7e-09	40	283
PTKc_Tie	cd05047	7.8e-07	40	288
PTKc_Met_Ron	cd05058	4.6e-16	40	290
PTKc_Syk_like	cd05060	2.6e-10	40	291
PTK_Jak1_rpt1	cd05077	6.1e-05	40	285
PTK_Jak2_Jak3_rpt1	cd05078	1.5e-07	40	285
PTKc_Fes	cd05084	6e-12	40	286
PTKc_Fer	cd05085	1.3e-11	40	286
PTKc_Aatyk2	cd05086	6e-05	40	288
PTKc_Aatyk1_Aatyk3	cd05087	0.00039	40	285
PTKc_Syk	cd05116	7.5e-10	40	286
STKc_PKC	cd05570	5.8e-14	40	296
STKc_PKB	cd05571	4.7e-17	40	357
STKc_SGK	cd05575	1.1e-08	40	342
STKc_aPKC	cd05588	4.3e-10	40	353
STKc_nPKC_eta	cd05590	3.6e-13	40	353
STKc_nPKC_epsilon	cd05591	2.4e-12	40	353
STKc_nPKC_theta_delt	cd05592	8.3e-20	40	354
STKc_SGK1	cd05602	1.6e-07	40	356
STKc_SGK2	cd05603	5.9e-09	40	342
STKc_SGK3	cd05604	3.9e-06	40	356
STKc_aPKC_zeta	cd05617	1.4e-09	40	353
STKc_aPKC_iota	cd05618	2.8e-07	40	353
STKc_nPKC_theta	cd05619	1e-11	40	356
STKc_nPKC_delta	cd05620	7.9e-07	40	344
PTKc_Zap-70	cd05115	1.1e-11	41	285
PKc	cd00180	2.8e-85	42	284
STKc_AGC	cd05123	5e-27	42	286
STKc_cGK_PKG	cd05572	7.6e-16	42	291
STKc_GRK	cd05577	2.2e-12	42	301
STKc_MAST_like	cd05579	1.7e-19	42	286
STKc_YPK1_like	cd05585	8.7e-14	42	339
STKc_Sck1_like	cd05586	3.9e-09	42	396
STKc_beta_ARK	cd05606	9.8e-11	42	302
STKc_GRK7	cd05607	2.5e-07	42	307
STKc_GRK1	cd05608	3.5e-14	42	306
STKc_GRK3	cd05633	8.8e-10	42	303
Pkinase	pfam00069	1.2e-90	36	286
Pkinase_Tyr	pfam07714	3e-40	36	285
TyrKc	smart00219	3.3e-33	36	286
STYKc	smart00221	3.7e-91	36	286
S_TKc	smart00220	2.5e-99	46	286
KIND	smart00750	1.1e-41	117	294

Table of Mutations found on the Protein

Source ↕	Mut_ID ↕	Class ↕	HGVS ↕	Disease ↕
Swiss-Prot	VAR_041148	Polymorphism	p.ALA414VAL	N/A
Swiss-Prot	VAR_041149	Polymorphism	p.LEU426ILE	N/A

Please Cite: Peterson, T.A., Adadey, A., Santana-Cruz ,I., Sun, Y., Winder A, Kann, M.G., (2010) DMDM: Domain Mapping of Disease Mutations. Bioinformatics 26 (19), 2458-2459.

DMDM_info@umbc.edu | 1000 Hilltop Circle, Baltimore, MD 21250 | Department of Biological Sciences | Phone: 410-455-2258