Results for the protein: P78536

Results for the Protein: P78536

14423632

6868

ADAM17

NCBI, UniProt

ADA17_HUMAN RecName: Full=Disintegrin and metalloproteinase domain-containing protein 17; Short=ADAM 17; AltName: Full=Snake venom-like protease; AltName: Full=TNF-alpha convertase; AltName: Full=TNF-alpha-converting enzyme; AltName: CD_antigen=CD156b; Flags: Precursor

			0 2 0 0 2

Tips:

The Domains on the Default View are decided by the Domain's E-Value.

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Default View: Pep_M12B_propep - pfam01562 ZnMc - cd00203 ZnMc_TACE_like - cd04270 ZnMc_ADAMTS_like - cd04273 ZnMc_adamalysin_II_l - cd04269 ZnMc_ADAM_like - cd04267 ZnMc_salivary_gland_ - cd04272 Reprolysin - pfam01421 DISIN - smart00050 Disintegrin - pfam00200	Swiss-Prot Protein: P78536 Identical to: NP_003174 Default View:

Domains found on the Protein

Domain ↕	CD Accession ↕	E-Value ↕	Start ↕	End ↕
ZnMc_ADAM_like	cd04267	8e-121	223	463
ZnMc_adamalysin_II_l	cd04269	3.1e-06	223	472
ZnMc_TACE_like	cd04270	5.9e-181	223	477
ZnMc_ADAMTS_like	cd04273	9.6e-07	223	471
ZnMc_salivary_gland_	cd04272	0.00067	224	471
Pep_M12B_propep	pfam01562	8.1e-08	5	167
Reprolysin	pfam01421	5.2e-06	226	474
Disintegrin	pfam00200	9.9e-26	484	561
DISIN	smart00050	1e-28	484	560

Table of Mutations found on the Protein

Source ↕	Mut_ID ↕	Class ↕	HGVS ↕	Disease ↕
Swiss-Prot	VAR_051587	Polymorphism	p.ARG202GLY	N/A
Swiss-Prot	VAR_051586	Polymorphism	p.LYS162GLU	N/A

Please Cite: Peterson, T.A., Adadey, A., Santana-Cruz ,I., Sun, Y., Winder A, Kann, M.G., (2010) DMDM: Domain Mapping of Disease Mutations. Bioinformatics 26 (19), 2458-2459.

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