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Results for the Protein: NP_001219
15718704
841

caspase-8 isoform A precursor [Homo sapiens]

Known Diseases associated with this Protein:
  BREAST CANCER, PROTECTION AGAINST
1
1
1
1
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Tips:
 The Domains on the Default View are decided by the Domain's E-Value.

 Clicking a check box will display or hide the correlated domain.

 To view the Gene page, either click on the link to the left or the blue bar above the Protein's graphic.



Default View:

DED - smart00031
DED_FADD - cd08336
DED_Caspase_10_repea - cd08341
DED_c-FLIP_repeat2 - cd08340
DED_PEA15 - cd08338
DED_Caspase_8_10_rep - cd08792
DED_Caspase_8_repeat - cd08333
DED - cd00045
DED_Caspase-like_rep - cd08776
DED - pfam01335
DED_c-FLIP_repeat1 - cd08337
DED_Caspase_10_repea - cd08814
DED_Caspase_8_repeat - cd08813
DED_Caspase_8_10_rep - cd08334
DED_Caspase-like_rep - cd08775
CASc - cd00032
CASc - smart00115
Peptidase_C14 - pfam00656


RefSeq Protein: NP_001219
   Default View:













Domains found on the Protein

Domain ↕CD Accession ↕E-Value ↕Start ↕End ↕
DED_FADDcd083362.1e-13182
DED_PEA15cd083380.00014184
DED_c-FLIP_repeat2cd083400.001178
DED_Caspase_10_repeacd083416.7e-08183
DEDcd000456.4e-15379
DED_Caspase_8_repeatcd083333.1e-54384
DED_Caspase-like_repcd087761.8e-21379
DED_Caspase_8_10_repcd087929.1e-26379
DED_c-FLIP_repeat1cd083370.00018487
DED_Caspase_10_repeacd088142.7e-06132212
DED_Caspase_8_10_repcd083341.5e-37134212
DED_Caspase-like_repcd087754.1e-44134210
DED_Caspase_8_repeatcd088135.2e-56134212
CASccd000322.1e-132242494
DEDpfam013351.4e-34386
DEDpfam013356.4e-25133215
Peptidase_C14pfam006562.3e-94251493
DEDsmart000311.3e-32180
DEDsmart000311.3e-22131210
CAScsmart001159.7e-141243495

Table of Mutations found on the Protein

Source ↕Mut_ID ↕Class ↕HGVS ↕Disease ↕
dbSNPrs1045485 Polymorphismp.ASP302HISN/A
OMIM601763.0003 Diseasep.ASP260HISBREAST CANCER, PROTECTION AGAINST



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