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Results for the Protein: NP_203522
15718712
841

caspase-8 isoform E [Homo sapiens]

Known Diseases associated with this Protein:
  BREAST CANCER, PROTECTION AGAINST
  CASPASE 8 DEFICIENCY
2
0
2
0
0
Tips:
 The Domains on the Default View are decided by the Domain's E-Value.

 Clicking a check box will display or hide the correlated domain.

 To view the Gene page, either click on the link to the left or the blue bar above the Protein's graphic.



Default View:

DED - smart00031
DED_FADD - cd08336
DED_Caspase_10_repea - cd08341
DED_c-FLIP_repeat2 - cd08340
DED_PEA15 - cd08338
DED_Caspase_8_10_rep - cd08792
DED - cd00045
DED - pfam01335
DED_Caspase_8_repeat - cd08333
DED_Caspase-like_rep - cd08776
DED_c-FLIP_repeat1 - cd08337
DED_Caspase_8_10_rep - cd08334
DED_Caspase_10_repea - cd08814
DED_Caspase_8_repeat - cd08813
DED_Caspase-like_rep - cd08775


RefSeq Protein: NP_203522
   Default View:













Domains found on the Protein

Domain ↕CD Accession ↕E-Value ↕Start ↕End ↕
DED_FADDcd083362.1e-13182
DED_PEA15cd083380.00014184
DED_c-FLIP_repeat2cd083400.001178
DED_Caspase_10_repeacd083416.7e-08183
DEDcd000456.4e-15379
DED_Caspase_8_repeatcd083333.1e-54384
DED_Caspase-like_repcd087761.8e-21379
DED_Caspase_8_10_repcd087929.1e-26379
DED_c-FLIP_repeat1cd083370.00018487
DED_Caspase_8_10_repcd083345e-4498180
DED_Caspase_8_repeatcd088132e-6298180
DED_Caspase_10_repeacd088145.3e-0998180
DED_Caspase-like_repcd087757.7e-4999178
DEDpfam013351.4e-34386
DEDpfam013359.5e-27101183
DEDsmart000311.3e-32180
DEDsmart000313e-2799178

Table of Mutations found on the Protein

Source ↕Mut_ID ↕Class ↕HGVS ↕Disease ↕
OMIM601763.0001 Diseasep.ARG189TRPCASPASE 8 DEFICIENCY
OMIM601763.0003 Diseasep.ASP221HISBREAST CANCER, PROTECTION AGAINST



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