Results for the protein: O14827

Results for the Protein: O14827

162416200

5924

RASGRF2

NCBI, UniProt

RGRF2_HUMAN RecName: Full=Ras-specific guanine nucleotide-releasing factor 2; Short=Ras-GRF2; AltName: Full=Ras guanine nucleotide exchange factor 2

			0 5 0 2 3

Tips:

The Domains on the Default View are decided by the Domain's E-Value.

Clicking a check box will display or hide the correlated domain.

To view the Gene page, either click on the link to the left or the blue bar above the Protein's graphic.

Default View: PH - pfam00169 PH - smart00233 PH - cd00821 - cd01246 PH-like - cd00900 RhoGEF - cd00160 RhoGEF - smart00325 RhoGEF - pfam00621 RasGEF_N - pfam00618 REM - cd06224 RasGEFN - smart00229 RasGEF - cd00155 RasGEF - smart00147 RasGEF - pfam00617	Swiss-Prot Protein: O14827 Identical to: NP_008840 Default View:

Domains found on the Protein

Domain ↕	CD Accession ↕	E-Value ↕	Start ↕	End ↕
PH-like	cd00900	1.1e-08	25	131
	cd01246	0.00018	25	131
RhoGEF	cd00160	5.6e-50	244	427
PH	cd00821	3.9e-07	462	586
REM	cd06224	5.4e-82	643	974
RasGEF	cd00155	9.2e-113	998	1230
PH	pfam00169	4.4e-21	23	133
RhoGEF	pfam00621	1.2e-46	248	428
PH	pfam00169	4.5e-09	460	588
RasGEF_N	pfam00618	3.9e-185	638	946
RasGEF	pfam00617	6.1e-86	999	1184
PH	smart00233	2.4e-17	23	133
RhoGEF	smart00325	1.2e-51	247	428
PH	smart00233	1.5e-09	460	588
RasGEFN	smart00229	1.8e-51	794	972
RasGEF	smart00147	1.4e-112	998	1235

Table of Mutations found on the Protein

Source ↕	Mut_ID ↕	Class ↕	HGVS ↕	Disease ↕
Swiss-Prot	VAR_037595	Polymorphism	p.ARG114HIS	N/A
Swiss-Prot	VAR_037596	Polymorphism	p.ASP538ASN	N/A
Swiss-Prot	VAR_037598	Polymorphism	p.ASP1216GLU	N/A
dbSNP	rs16878472	Polymorphism	p.LEU713TRP	N/A
dbSNP	rs34193571	Polymorphism	p.SER753PRO	N/A

Please Cite: Peterson, T.A., Adadey, A., Santana-Cruz ,I., Sun, Y., Winder A, Kann, M.G., (2010) DMDM: Domain Mapping of Disease Mutations. Bioinformatics 26 (19), 2458-2459.

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