Results for the protein: P43250

Results for the Protein: P43250

20141386

2870

GRK6

NCBI, UniProt

GRK6_HUMAN RecName: Full=G protein-coupled receptor kinase 6; AltName: Full=G protein-coupled receptor kinase GRK6

			0 4 0 1 3

Tips:

The Domains on the Default View are decided by the Domain's E-Value.

Clicking a check box will display or hide the correlated domain.

To view the Gene page, either click on the link to the left or the blue bar above the Protein's graphic.

Swiss-Prot Protein: P43250

Identical to: NP_001004106

Default View:

Domains found on the Protein

Domain ↕	CD Accession ↕	E-Value ↕	Start ↕	End ↕
STKc_ROCK2	cd05621	2.2e-13	160	500
STKc_ROCK1	cd05622	1.2e-11	160	501
STKc_PAK6	cd06659	3.8e-09	162	474
STKc_PAK_I	cd06647	3.4e-06	163	473
STKc_PAK4	cd06657	2.8e-08	163	455
STKc_PAK5	cd06658	1.4e-07	164	466
STKc_JNK2	cd07876	3.3e-07	164	479
STKc_myosinIIIB	cd06639	4.2e-07	165	449
STKc_myosinIIIA	cd06638	1e-06	167	448
STKc_PAK_II	cd06648	8.7e-12	167	461
STKc_p38	cd07851	2.5e-10	167	496
STKc_ERK5	cd07855	7.7e-09	167	481
STKc_JNK1	cd07875	1.1e-05	168	481
STKc_MAP4K4_6	cd06636	0.00026	169	448
STKc_JNK	cd07850	8.8e-07	169	491
STKc_PAK	cd06614	1.6e-17	170	461
STKc_TAO	cd06607	0.0008	171	462
STKc_PAK1	cd06654	4.3e-07	172	475
STKc_PAK2	cd06655	1.3e-07	172	476
STKc_PAK3	cd06656	1e-07	172	477
STKc_JNK3	cd07874	1.2e-06	172	522
STKc_STK10_LOK	cd06644	1.1e-07	173	467
STKc_p38alpha_MAPK14	cd07877	1.4e-06	174	523
PTKc_Chk	cd05083	3.7e-07	175	444
STKc_CDK12	cd07864	8.4e-10	175	448
STKc_CDK9	cd07865	9.5e-10	175	448
STKc_ASK	cd06624	3.4e-08	176	448
STKc_MAP4K3	cd06645	8.5e-07	176	447
STKc_p38beta_MAPK11	cd07878	1.8e-05	176	496
STKc_p38delta_MAPK13	cd07879	0.00011	176	493
PKc_MKK7	cd06618	1.2e-09	177	462
STKc_TNIK	cd06637	8.5e-06	177	448
STKc_CDK10	cd07845	5.9e-08	177	467
PTKc_DDR2	cd05095	1.1e-05	178	457
PTKc_DDR1	cd05096	0.00042	178	458
PTK_HER3	cd05111	0.00011	178	435
STKc_p38gamma_MAPK12	cd07880	1.7e-08	178	529
PTKc_ALK_LTK	cd05036	9.5e-08	179	434
PTKc_EGFR_like	cd05057	1.3e-05	179	435
PTKc_FAK	cd05056	1.1e-05	179	444
PTKc_Tie2	cd05088	5.9e-05	179	458
STKc_MAP4K5	cd06646	1.2e-06	179	447
PTK_CCK4	cd05046	0.00016	180	430
PTKc_Ror	cd05048	1.1e-05	180	419
PTKc_Trk	cd05049	5.2e-05	180	434
PTKc_EphR_A2	cd05063	0.00048	180	452
PTKc_Ror1	cd05090	0.00023	180	444
PTKc_DDR_like	cd05097	1.8e-06	180	457
PKc_MEK2	cd06649	1.2e-05	180	536
PKc_MEK1	cd06650	9.4e-05	180	540
PTKc_InsR_like	cd05032	4.3e-07	181	427
PTKc_EphR	cd05033	2.4e-05	181	424
PTKc_Src_like	cd05034	4e-07	181	426
PTKc_Jak_rpt2	cd05038	4.3e-08	181	431
PTK_Ryk	cd05043	9.6e-06	181	432
PTKc_Musk	cd05050	6.1e-06	181	445
PTKc_Abl	cd05052	4.2e-06	181	447
PTKc_Tec_like	cd05059	7.4e-05	181	424
PTKc_InsR	cd05061	1.8e-06	181	453
PTKc_IGF-1R	cd05062	1.2e-06	181	441
PTKc_EphR_B	cd05065	0.00024	181	451
PTKc_EphR_A	cd05066	0.0005	181	452
PTKc_Lck_Blk	cd05067	9.5e-05	181	453
PTKc_Frk_like	cd05068	6.8e-08	181	458
PTKc_Yes	cd05069	7.4e-07	181	443
PTKc_Fyn_Yrk	cd05070	6.6e-06	181	445
PTKc_Src	cd05071	1.4e-05	181	446
PTKc_Lyn	cd05072	6.3e-05	181	426
PTKc_Hck	cd05073	0.00017	181	428
PTKc_Jak1_rpt2	cd05079	0.0003	181	449
PTKc_Tyk2_rpt2	cd05080	4.4e-07	181	458
PTKc_Csk	cd05082	2.2e-05	181	446
PTKc_TrkA	cd05092	0.00059	181	434
PTKc_TrkB	cd05093	0.001	181	450
PTKc_TrkC	cd05094	0.0004	181	492
PTKc_Jak2_Jak3_rpt2	cd05081	1.4e-07	181	460
PTKc_EGFR	cd05108	7.1e-05	181	473
PTKc_HER2	cd05109	2.5e-05	181	435
PTKc_Itk	cd05112	4.2e-06	181	428
PTKc_Btk_Bmx	cd05113	3.3e-06	181	428
PTKc_Tec_Rlk	cd05114	8.1e-06	181	446
PKc_MAPKK_Byr1_like	cd06620	3.3e-08	181	458
STKc_TEY_MAPK_plant	cd07858	5.6e-08	181	493
STKc_MST1_2	cd06612	9.9e-11	182	448
STKc_MAP4K3_like	cd06613	3.5e-12	182	447
PKc_MKK4	cd06616	3.1e-07	182	478
STKc_MST4	cd06640	8.9e-07	182	469
STKc_MST3	cd06641	3.9e-07	182	469
STKc_STK25-YSK1	cd06642	1.1e-07	182	469
STKc_PCTAIRE_like	cd07844	3.4e-11	182	483
STKc_Sty1_Hog1	cd07856	5.3e-07	182	475
STKc_PFTAIRE1	cd07869	8e-06	182	460
STKc_PFTAIRE2	cd07870	1.6e-07	182	465
PTKc_Srm_Brk	cd05148	5.4e-06	183	459
STKc_SLK	cd06643	3.5e-06	183	465
STKc_MEKK3_like_1	cd06653	4.9e-08	183	448
STKc_MEKK2	cd06652	8e-06	183	449
STKc_ERK1_2_like	cd07849	1.3e-07	183	493
STKc_Nek6_Nek7	cd08224	4.8e-16	183	444
PTKc_Tie1	cd05089	0.00092	184	459
STKc_ROCK_NDR_like	cd05573	3.8e-32	184	532
STKc_phototropin_lik	cd05574	1.8e-29	184	474
STKc_PKA	cd05580	2.2e-55	184	486
STKc_PDK1	cd05581	2.4e-51	184	448
STKc_DMPK_like	cd05597	3.3e-42	184	512
STKc_LATS	cd05598	2.3e-17	184	521
STKc_NDR_like	cd05599	4.5e-15	184	503
STKc_Sid2p_Dbf2p	cd05600	2e-15	184	501
STKc_MAST	cd05609	1.1e-36	184	475
STKc_CRIK	cd05601	3.1e-16	184	503
STKc_PRKX_like	cd05612	4.7e-47	184	484
STKc_MRCK_alpha	cd05623	4.6e-18	184	513
STKc_MRCK_beta	cd05624	1.1e-22	184	512
STKc_LATS1	cd05625	1.2e-18	184	521
STKc_LATS2	cd05626	1.1e-14	184	527
STKc_NDR2	cd05627	2.2e-10	184	537
STKc_NDR1	cd05628	7.4e-12	184	503
STKc_NDR_like_fungal	cd05629	4.3e-24	184	525
PKc_MAPKK	cd06605	2.5e-11	184	453
STKc_myosinIII_like	cd06608	1.6e-07	184	448
STKc_MST3_like	cd06609	4.7e-13	184	461
PKc_MEK	cd06615	9.4e-10	184	460
PKc_MKK3_6	cd06617	1.4e-08	184	462
PKc_MKK5	cd06619	2.9e-05	184	470
PKc_MAPKK_Pek1_like	cd06621	7e-08	184	461
PKc_MAPKK_PBS2_like	cd06622	1.7e-08	184	501
PKc_MAPKK_plant_like	cd06623	1.6e-17	184	453
STKc_MEKK3_like	cd06625	3.7e-13	184	448
STKc_NAK1_like	cd06917	8.9e-08	184	452
STKc_CDKL	cd07833	5.7e-09	184	448
STKc_CdkB_plant	cd07837	2.1e-12	184	449
STKc_CDKL1_4	cd07847	2.2e-09	184	483
STKc_CDKL5	cd07848	4.5e-05	184	448
STKc_PCTAIRE3	cd07871	1.3e-07	184	465
STKc_PCTAIRE2	cd07872	1.6e-06	184	476
STKc_PCTAIRE1	cd07873	3.8e-06	184	458
STKc_Nek7	cd08229	7.5e-18	184	446
STKc_Nek6	cd08228	2.8e-18	184	444
SPS1	COG0515	9.7e-57	184	573
PTKc_RET	cd05045	1.6e-05	185	435
PKc_STE	cd05122	7.2e-22	185	447
STKc_Yank1	cd05578	5.6e-75	185	448
STKc_MSK_N	cd05583	8.3e-67	185	467
STKc_cPKC	cd05587	6.3e-72	185	513
STKc_GRK4_like	cd05605	1.4e-218	185	469
STKc_MSK1_N	cd05613	3.2e-52	185	467
STKc_MSK2_N	cd05614	2.1e-50	185	507
STKc_cPKC_alpha	cd05615	3.8e-57	185	510
STKc_cPKC_beta	cd05616	3.8e-56	185	525
STKc_GRK6	cd05630	1e-255	185	469
STKc_GRK4	cd05631	3.5e-217	185	469
STKc_GRK5	cd05632	6.6e-212	185	469
STKc_MAPKKK	cd06606	2.7e-35	185	448
STKc_Cdc7_like	cd06627	2.7e-15	185	448
STKc_MAPKKK_Byr2_lik	cd06628	4.1e-17	185	448
STKc_MEKK1	cd06630	2.8e-10	185	449
STKc_YSK4	cd06631	4.9e-09	185	448
STKc_MEKK1_plant	cd06632	9.7e-14	185	448
STKc_MEKK3	cd06651	2.4e-09	185	451
STKc_MAPK	cd07834	5.8e-09	185	495
STKc_Pho85	cd07836	1.6e-13	185	483
STKc_CDK7	cd07841	2.9e-11	185	457
STKc_CDK5	cd07839	4.3e-07	185	448
STKc_NLK	cd07853	1.3e-05	185	521
STKc_MPK1	cd07857	2e-08	185	489
STKc_TDY_MAPK_plant	cd07859	3.6e-07	185	493
STKc_CDK2_3	cd07860	8.2e-11	185	448
STKc_CDK1_euk	cd07861	4.6e-07	185	448
STKc_CDK4	cd07863	1.2e-06	185	448
STKc_BUR1	cd07866	1.4e-10	185	448
STKc_Nek	cd08215	3.1e-27	185	448
STKc_Nek1	cd08218	9.5e-24	185	448
STKc_Nek3	cd08219	5.8e-16	185	443
STKc_Nek9	cd08221	7.9e-11	185	448
STKc_Nek11	cd08222	1.7e-08	185	448
STKc_Nek4	cd08223	2.8e-22	185	448
STKc_Nek5	cd08225	2.2e-13	185	448
STKc_Nek8	cd08220	1.2e-09	185	448
STKc_Nek10	cd08528	4.4e-10	185	443
STKc_FA2-like	cd08529	2.8e-11	185	432
STKc_CNK2-like	cd08530	1.3e-13	185	448
PTKc_Axl_like	cd05035	3.6e-05	186	447
PTKc_Tyro3	cd05074	0.00011	186	433
STKc_CMGC	cd05118	9.5e-18	186	448
STKc_PKN	cd05589	9.2e-60	186	505
STKc_MAPKKK_Bck1_lik	cd06629	1.3e-10	186	448
STKc_CDK_like	cd07829	1.1e-14	186	448
STKc_MAK_like	cd07830	1.8e-11	186	448
STKc_CDK1_like	cd07835	1.2e-08	186	448
STKc_CDK4_6_like	cd07838	2.7e-09	186	448
STKc_MAPK4_6	cd07854	5.2e-05	186	494
STKc_CDK8	cd07868	0.00061	186	448
STKc_OSR1_SPAK	cd06610	2.7e-12	187	448
STKc_CDKL2_3	cd07846	2.7e-09	187	483
STKc_CDK6	cd07862	5.3e-05	187	474
STKc_MEKK4	cd06626	3.2e-10	188	448
STKc_CCRK	cd07832	4.8e-15	188	449
STKc_CDC2L1	cd07843	4.8e-06	188	448
STKc_CDK8_like	cd07842	8.5e-08	188	448
STKc_Nek2	cd08217	7.9e-14	188	448
STKc_RSK_N	cd05582	2.2e-57	189	508
STKc_p70S6K	cd05584	1.7e-59	189	518
STKc_MOK	cd07831	4.4e-14	189	448
STKc_CDK9_like	cd07840	3.1e-11	189	448
PTKc	cd00192	1.8e-11	190	447
PTKc_Ack_like	cd05040	1.4e-07	190	429
PTKc_Fes_like	cd05041	4.1e-08	190	426
PTKc_c-ros	cd05044	3.2e-05	190	449
PTKc_Tie	cd05047	0.00074	190	462
PTKc_Met_Ron	cd05058	4.1e-05	190	462
PTKc_Syk_like	cd05060	1.3e-05	190	429
PTKc_Fes	cd05084	1.5e-07	190	443
PTKc_Fer	cd05085	3.3e-06	190	429
PTKc_Syk	cd05116	5e-05	190	449
STKc_PKB	cd05571	6.7e-71	190	524
STKc_SGK	cd05575	9.6e-59	190	533
STKc_PKC	cd05570	2.9e-60	190	500
STKc_aPKC	cd05588	3.2e-54	190	525
STKc_nPKC_eta	cd05590	7.3e-58	190	506
STKc_nPKC_epsilon	cd05591	9.1e-57	190	509
STKc_PKB_gamma	cd05593	6.4e-49	190	521
STKc_PKB_alpha	cd05594	2.1e-57	190	521
STKc_PKB_beta	cd05595	1.9e-57	190	518
STKc_SGK1	cd05602	2.8e-43	190	536
STKc_SGK2	cd05603	4.1e-46	190	509
STKc_SGK3	cd05604	1.9e-54	190	535
STKc_nPKC_theta_delt	cd05592	1.5e-61	190	510
STKc_aPKC_iota	cd05618	4.1e-42	190	525
STKc_nPKC_theta	cd05619	1e-50	190	507
STKc_nPKC_delta	cd05620	4.5e-47	190	507
STKc_aPKC_zeta	cd05617	6.9e-49	190	525
STKc_beta_ARK	cd05606	2.5e-92	191	468
STKc_GRK3	cd05633	1.8e-91	191	469
PKc	cd00180	4.8e-66	192	446
PTKc_Zap-70	cd05115	5.4e-05	192	446
STKc_AGC	cd05123	2.3e-127	192	448
STKc_cGK_PKG	cd05572	4.8e-56	192	455
STKc_GRK	cd05577	6.1e-239	192	468
STKc_MAST_like	cd05579	8.6e-37	192	453
STKc_YPK1_like	cd05585	1.7e-63	192	507
STKc_Sck1_like	cd05586	1.4e-49	192	561
STKc_GRK7	cd05607	3.8e-132	192	468
STKc_GRK1	cd05608	3.7e-137	192	468
STKc_SLK_like	cd06611	2.5e-08	192	462
STKc_Rim15_like	cd05611	8.5e-15	194	454
STKc_MAPK15	cd07852	3.1e-07	237	476
RGS	pfam00615	1.1e-33	52	170
Pkinase	pfam00069	1.2e-78	186	448
RGS	smart00315	9.8e-34	35	170
Pkinase_Tyr	pfam07714	4.7e-14	186	423
TyrKc	smart00219	7.5e-14	186	423
STYKc	smart00221	1.5e-77	186	448
S_TKc	smart00220	4.9e-90	196	448
S_TK_X	smart00133	2.9e-08	449	528

Table of Mutations found on the Protein

Source ↕	Mut_ID ↕	Class ↕	HGVS ↕	Disease ↕
dbSNP	rs2230881	Polymorphism	p.ARG132GLN	N/A
Swiss-Prot	VAR_040524	Polymorphism	p.ARG31GLN	N/A
Swiss-Prot	VAR_040526	Polymorphism	p.ILE275MET	N/A
Swiss-Prot	VAR_040525	Polymorphism	p.THR73MET	N/A

Please Cite: Peterson, T.A., Adadey, A., Santana-Cruz ,I., Sun, Y., Winder A, Kann, M.G., (2010) DMDM: Domain Mapping of Disease Mutations. Bioinformatics 26 (19), 2458-2459.

DMDM_info@umbc.edu | 1000 Hilltop Circle, Baltimore, MD 21250 | Department of Biological Sciences | Phone: 410-455-2258