Results for the protein: NP

Results for the Protein: NP_001129080

208022687

23092

ARHGAP26

NCBI

rho GTPase-activating protein 26 isoform b [Homo sapiens]

Known Diseases associated with this Protein:
LEUKEMIA, JUVENILE MYELOMONOCYTIC, SOMATIC

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RefSeq Protein: NP_001129080

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Domains found on the Protein

Domain ↕	CD Accession ↕	E-Value ↕	Start ↕	End ↕
BAR_RhoGAP_OPHN1-lik	cd07602	1.7e-146	19	225
BAR_ACAPs	cd07603	3.4e-11	19	225
BAR_ASAPs	cd07604	0.00072	19	228
BAR_APPL1	cd07631	0.00023	19	233
BAR_OPHN1	cd07633	3.8e-95	19	225
BAR_GAP10-like	cd07634	2e-118	19	225
BAR_GRAF2	cd07635	2.1e-117	19	225
BAR_GRAF	cd07636	8.4e-158	19	225
BAR_ACAP3	cd07637	9.6e-09	19	225
BAR_ACAP2	cd07638	4.7e-06	19	225
BAR_SFC_plant	cd07606	0.00038	20	224
BAR	cd07307	1.6e-24	28	227
PH	cd00821	1.3e-06	268	367
BAR-PH_GRAF_family	cd01249	6.6e-80	268	367
PH_AGAP	cd01250	0.00033	268	367
RhoGAP_Graf	cd04374	6.1e-158	364	563
RhoGAP_CdGAP	cd04384	1.9e-13	369	563
RhoGAP_srGAP	cd04383	1.1e-06	369	562
RhoGAP-ARHGAP11A	cd04394	6.4e-07	370	576
RhoGAP_SYD1	cd04379	4.9e-09	374	565
RhoGAP_Bcr	cd04387	2.4e-18	374	563
RhoGAP_PARG1	cd04409	3.9e-21	374	563
RhoGAP_GMIP_PARG1	cd04378	1.7e-23	375	563
RhoGAP_fSAC7_BAG7	cd04396	1.3e-05	375	568
RhoGap_RalBP1	cd04381	2.5e-09	376	555
RhoGAP_nadrin	cd04386	1.8e-19	376	572
RhoGAP_GMIP	cd04408	4.7e-20	376	563
RhoGAP_myosin_IXB	cd04407	9.9e-15	377	563
RhoGAP_myosin_IXA	cd04406	2.2e-08	377	563
RhoGAP_FAM13A1a	cd04393	7.9e-07	378	563
RhoGAP_p190	cd04373	6.2e-12	380	563
RhoGAP_MgcRacGAP	cd04382	1.3e-13	380	562
RhoGAP_ARAP	cd04385	2.5e-21	380	564
RhoGAP_fBEM3	cd04400	6.3e-09	380	571
RhoGAP-p50rhoGAP	cd04404	4.5e-12	380	568
RhoGAP_ARHGAP19	cd04392	2.7e-06	381	581
RhoGAP_ARHGAP22_24_2	cd04390	5.3e-11	381	568
RhoGAP_chimaerin	cd04372	2.4e-31	382	568
RhoGAP_DLC1	cd04375	2.8e-05	382	574
RhoGAP_myosin_IX	cd04377	1.1e-11	383	563
RhoGAP_p85	cd04388	3.1e-05	383	580
RhoGAP_fRGD1	cd04398	3.6e-25	383	568
RhoGAP_ARHGAP27_15_1	cd04403	1.7e-29	383	563
RhoGAP_ARHGAP6	cd04376	1.3e-09	384	574
RhoGAP_ARHGAP18	cd04391	3.3e-08	384	580
RhoGAP_ARHGAP21	cd04395	1.6e-14	387	568
RhoGAP	cd00159	8.3e-56	390	563
RhoGAP_fLRG1	cd04397	1.6e-05	404	574
RhoGAP_ARHGAP20	cd04402	2.8e-06	408	570
SH3	cd00174	2e-17	705	758
PH	pfam00169	1e-09	266	369
RhoGAP	pfam00620	1.1e-42	391	546
SH3_1	pfam00018	6.4e-09	707	753
PH	smart00233	2.8e-08	266	369
RhoGAP	smart00324	6.5e-67	387	564
SH3	smart00326	2.1e-18	702	759

Table of Mutations found on the Protein

Source ↕	Mut_ID ↕	Class ↕	HGVS ↕	Disease ↕
OMIM	605370.0001	Disease	p.ASN417SER	LEUKEMIA, JUVENILE MYELOMONOCYTIC, SOMATIC

Please Cite: Peterson, T.A., Adadey, A., Santana-Cruz ,I., Sun, Y., Winder A, Kann, M.G., (2010) DMDM: Domain Mapping of Disease Mutations. Bioinformatics 26 (19), 2458-2459.

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