Results for the protein: NP

Domains found on the Protein

Domain ↕	CD Accession ↕	E-Value ↕	Start ↕	End ↕
NR_DBD_TLX	cd07163	1.2e-13	544	650
NR_DBD_VDR	cd06955	9.9e-14	550	652
NR_DBD_PNR	cd06970	4.2e-12	552	638
NR_DBD_GCNF_like	cd07169	1.8e-19	552	639
NR_DBD_ERR	cd07170	8.2e-21	554	648
NR_DBD_TR2_like	cd06967	8.6e-21	555	642
NR_DBD_ER	cd07171	1.3e-28	555	636
NR_DBD_AR	cd07173	9e-62	555	636
NR_DBD_GR_PR	cd07172	3.4e-50	556	633
NR_DBD_FXR	cd06962	5.2e-17	557	640
NR_DBD_RAR	cd06964	6.2e-17	557	634
NR_DBD_EcR	cd07161	5e-19	557	647
NR_DBD_REV_ERB	cd07166	1.3e-14	557	642
NR_DBD_DHR4_like	cd07168	7.4e-17	557	639
NR_DBD_RXR	cd06956	3.3e-18	558	634
NR_DBD_CAR	cd06966	2.3e-15	558	645
NR_DBD_NGFI-B	cd06969	3.7e-21	558	632
2DBD_NR_DBD1	cd07157	8.8e-17	558	640
NR_DBD_EcR_like	cd06959	5.7e-21	559	631
NR_DBD_TR	cd06961	2.1e-19	559	641
NR_DBD_Ppar	cd06965	3.8e-13	559	643
NR_DBD_ROR	cd06968	7.4e-19	559	647
NR_DBD_PXR	cd07162	1.8e-13	559	641
NR_DBD_like	cd06916	1.8e-37	560	631
NR_DBD_PNR_like_2	cd06957	2.7e-17	560	641
NR_DBD_COUP_TF	cd06958	6e-19	560	632
NR_DBD_HNF4A	cd06960	6.6e-27	560	635
NR_DBD_GR_like	cd06963	1.4e-56	560	632
NR_DBD_PNR_like	cd07154	7e-20	560	631
NR_DBD_VDR_like	cd07156	2.3e-20	560	627
NR_DBD_Ppar_like	cd07158	6.2e-18	560	631
NR_DBD_ER_like	cd07155	2.4e-24	560	634
NR_DBD_PNR_like_1	cd07164	3.2e-20	560	637
NR_DBD_DmE78_like	cd07165	8.5e-16	560	640
NR_DBD_Lrh-1_like	cd07167	3.4e-20	560	652
2DBD_NR_DBD2	cd07179	9.6e-18	560	633
NR_LBD_Nurr1_like	cd06945	0.00039	646	892
NR_LBD_ER	cd06949	1.8e-06	669	903
NR_LBD_SF-1	cd07070	0.00099	672	903
NR_LBD_RXR_like	cd06943	3.3e-07	673	859
NR_LBD_GR_Like	cd06947	4e-177	673	918
NR_LBD_AR	cd07073	4.1e-204	673	918
NR_LBD_PR	cd07074	2.2e-123	673	920
NR_LBD_MR	cd07075	1.4e-89	673	920
NR_LBD_GR	cd07076	1.8e-107	673	920
NR_LBD_ERR	cd06946	4.3e-10	674	898
NR_LBD_DHR4_like	cd06953	0.0001	674	885
NR_LBD_ER_like	cd07068	4.7e-13	674	898
NR_LBD_HNF4_like	cd06931	2.8e-06	675	895
NR_LBD_Ftz-F1_like	cd06944	0.00061	677	884
NR_LBD_F1	cd06929	3.1e-05	699	878
NR_LBD_F2	cd06930	9.7e-63	702	870
NR_LBD	cd06157	2.9e-50	703	870
Androgen_recep	pfam02166		6	449
zf-C4	pfam00105	1.2e-40	558	627
Hormone_recep	pfam00104	1.6e-35	733	899
ZnF_C4	smart00399	9.1e-33	559	628
HOLI	smart00430	7.9e-35	709	870

Table of Mutations found on the Protein

Source ↕	Mut_ID ↕	Class ↕	HGVS ↕	Disease ↕
OMIM	313700.0032	Disease	p.ALA721THR	PROSTATE CANCER
OMIM	313700.0011	Disease	p.ALA771THR	ANDROGEN INSENSITIVITY, PARTIAL
OMIM	313700.0010	Disease	p.ARG772CYS	ANDROGEN INSENSITIVITY, COMPLETE
OMIM	313700.0003	Disease	p.ARG773CYS	ANDROGEN INSENSITIVITY, COMPLETE
OMIM	313700.0026	Disease	p.ARG839CYS	ANDROGEN INSENSITIVITY, PARTIAL
OMIM	313700.0054	Disease	p.ARG840CYS	ANDROGEN INSENSITIVITY SYNDROME
OMIM	313700.0016	Disease	p.ARG607GLN	ANDROGEN INSENSITIVITY, PARTIAL, WITH OR WITHOUT BREAST CANCER
OMIM	313700.0015	Disease	p.ARG773HIS	ANDROGEN INSENSITIVITY, COMPLETE
OMIM	313700.0025	Disease	p.ARG839HIS	ANDROGEN INSENSITIVITY, PARTIAL
OMIM	313700.0040	Disease	p.ARG846HIS	ANDROGEN INSENSITIVITY, PARTIAL
OMIM	313700.0019	Disease	p.ARG855HIS	ANDROGEN INSENSITIVITY, PARTIAL
OMIM	313700.0047	Disease	p.ARG726LEU	PROSTATE CANCER SUSCEPTIBILITY
OMIM	313700.0024	Disease	p.ARG608LYS	ANDROGEN INSENSITIVITY, PARTIAL, WITH BREAST CANCER
OMIM	313700.0035	Disease	p.CYS579PHE	ANDROGEN INSENSITIVITY, COMPLETE
OMIM	313700.0031	Disease	p.GLN902ARG	PROSTATE CANCER
OMIM	313700.0043	Disease	p.GLN798GLU	ANDROGEN INSENSITIVITY, PARTIAL
OMIM	313700.0021	Disease	p.GLN60TER	ANDROGEN INSENSITIVITY, COMPLETE
OMIM	313700.0038	Disease	p.GLU2LYS	ANDROGEN INSENSITIVITY, PARTIAL
OMIM	313700.0051	Disease	p.GLY577ARG	ANDROGEN INSENSITIVITY SYNDROME
OMIM	313700.0057	Disease	p.GLY743GLU	ANDROGEN INSENSITIVITY, COMPLETE
OMIM	313700.0056	Disease	p.GLY743VAL	ANDROGEN INSENSITIVITY, PARTIAL\|\|ANDROGEN INSENSITIVITY, COMPLETE, INCLUDED
OMIM	313700.0055	Disease	p.HIS689PRO	ANDROGEN INSENSITIVITY, COMPLETE
OMIM	313700.0030	Disease	p.HIS874TYR	PROSTATE CANCER
OMIM	313700.0020	Disease	p.ILE869MET	HYPOSPADIAS 1, X-LINKED
OMIM	313700.0034	Disease	p.LEU707ARG	ANDROGEN INSENSITIVITY, COMPLETE
OMIM	313700.0050	Disease	p.LEU712PHE	ANDROGEN INSENSITIVITY SYNDROME
OMIM	313700.0028	Disease	p.LEU676PRO	ANDROGEN INSENSITIVITY, COMPLETE
OMIM	313700.0042	Disease	p.LEU172TER	ANDROGEN INSENSITIVITY, PARTIAL
OMIM	313700.0007	Disease	p.LYS588TER	ANDROGEN INSENSITIVITY, COMPLETE
OMIM	313700.0009	Disease	p.LYS882TER	ANDROGEN INSENSITIVITY, COMPLETE
OMIM	313700.0039	Disease	p.MET780ILE	ANDROGEN INSENSITIVITY, COMPLETE
OMIM	313700.0044	Disease	p.MET807THR	ANDROGEN INSENSITIVITY, PARTIAL
OMIM	313700.0012	Disease	p.MET786VAL	ANDROGEN INSENSITIVITY, COMPLETE
OMIM	313700.0053	Disease	p.PHE856LEU	ANDROGEN INSENSITIVITY SYNDROME
OMIM	313700.0036	Disease	p.PHE582TYR	ANDROGEN INSENSITIVITY, COMPLETE
OMIM	313700.0037	Disease	p.PRO546SER	HYPOSPADIAS 1, X-LINKED
OMIM	313700.0033	Disease	p.SER647ASN	PROSTATE CANCER
OMIM	313700.0059	Disease	p.SER740CYS	ANDROGEN INSENSITIVITY, PARTIAL
OMIM	313700.0052	Disease	p.SER865PRO	ANDROGEN INSENSITIVITY SYNDROME
OMIM	313700.0048	Disease	p.SER888SER	ANDROGEN INSENSITIVITY SYNDROME
OMIM	313700.0027	Disease	p.THR877ALA	PROSTATE CANCER
OMIM	313700.0029	Disease	p.THR877SER	PROSTATE CANCER
OMIM	313700.0004	Disease	p.TRP717TER	ANDROGEN INSENSITIVITY, COMPLETE
OMIM	313700.0006	Disease	p.TRP794TER	ANDROGEN INSENSITIVITY, COMPLETE
OMIM	313700.0008	Disease	p.TYR761CYS	ANDROGEN INSENSITIVITY, PARTIAL
OMIM	313700.0018	Disease	p.VAL865LEU	ANDROGEN INSENSITIVITY, PARTIAL
OMIM	313700.0013	Disease	p.VAL730MET	PROSTATE CANCER
OMIM	313700.0017	Disease	p.VAL865MET	ANDROGEN INSENSITIVITY, COMPLETE
OMIM	313700.0005	Disease	p.VAL866MET	ANDROGEN INSENSITIVITY, COMPLETE

Please Cite: Peterson, T.A., Adadey, A., Santana-Cruz ,I., Sun, Y., Winder A, Kann, M.G., (2010) DMDM: Domain Mapping of Disease Mutations. Bioinformatics 26 (19), 2458-2459.

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