Results for the protein: O95602

Results for the Protein: O95602

215273873

25885

POLR1A

NCBI, UniProt

RPA1_HUMAN RecName: Full=DNA-directed RNA polymerase I subunit RPA1; Short=RNA polymerase I subunit A1; AltName: Full=A190; AltName: Full=DNA-directed RNA polymerase I largest subunit; AltName: Full=DNA-directed RNA polymerase I subunit A; AltName: Full=RNA polymerase I 194 kDa subunit; Short=RPA194

			0 8 0 5 3

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Default View: RpoC - COG0086 RNA_pol_Rpb1_1 - pfam04997 RPOLA_N - smart00663 RNA_pol_Rpb1_2 - pfam00623 RNA_pol_Rpb1_3 - pfam04983 RNA_pol_Rpb1_4 - pfam05000 RNA_pol_Rpb1_5 - pfam04998 RNAP_A'' - cd06528 RNAP_II_Rpb1_C - cd02584 RNAP_I_Rpa1_C - cd02735 RNAP_III_Rpc1_C - cd02736 RNAP_beta'_C - cd02655 RNAP_largest_subunit - cd00630	Swiss-Prot Protein: O95602 Identical to: NP_056240 Default View:

Domains found on the Protein

Domain ↕	CD Accession ↕	E-Value ↕	Start ↕	End ↕
RNAP_A''	cd06528	1.9e-13	1169	1718
RNAP_II_Rpb1_C	cd02584	1.3e-20	1182	1718
RNAP_III_Rpc1_C	cd02736	2.2e-20	1199	1713
RNAP_I_Rpa1_C	cd02735	1.2e-268	1199	1716
RNAP_beta'_C	cd02655	6.5e-06	1203	1712
RNAP_largest_subunit	cd00630	4.6e-56	1208	1712
RNA_pol_Rpb1_1	pfam04997	1.2e-05	9	432
RNA_pol_Rpb1_2	pfam00623	8e-109	434	614
RNA_pol_Rpb1_3	pfam04983	2.5e-58	617	802
RNA_pol_Rpb1_4	pfam05000	2.2e-34	837	951
RNA_pol_Rpb1_5	pfam04998	1.7e-288	958	1672
RPOLA_N	smart00663	3.8e-163	295	639

Table of Mutations found on the Protein

Source ↕	Mut_ID ↕	Class ↕	HGVS ↕	Disease ↕
dbSNP	rs34892520	Polymorphism	p.ALA1141THR	N/A
dbSNP	rs78239085	Polymorphism	p.ARG1387GLN	N/A
Swiss-Prot	VAR_047494	Polymorphism	p.GLN349GLU	N/A
Swiss-Prot	VAR_047499	Polymorphism	p.ILE1608MET	N/A
dbSNP	rs34302587	Polymorphism	p.ILE815VAL	N/A
dbSNP	rs35239368	Polymorphism	p.LYS364GLU	N/A
dbSNP	rs4832242	Polymorphism	p.PRO150ALA	N/A
Swiss-Prot	VAR_047496	Polymorphism	p.SER396ASN	N/A

Please Cite: Peterson, T.A., Adadey, A., Santana-Cruz ,I., Sun, Y., Winder A, Kann, M.G., (2010) DMDM: Domain Mapping of Disease Mutations. Bioinformatics 26 (19), 2458-2459.

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