Results for the protein: Q00722

Results for the Protein: Q00722

215273902

5330

PLCB2

NCBI, UniProt

PLCB2_HUMAN RecName: Full=1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2; AltName: Full=Phosphoinositide phospholipase C-beta-2; AltName: Full=Phospholipase C-beta-2; Short=PLC-beta-2

			0 6 0 1 5

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Swiss-Prot Protein: Q00722

Identical to: NP_004564

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Domains found on the Protein

Domain ↕	CD Accession ↕	E-Value ↕	Start ↕	End ↕
PI-PLCc	cd00137	3.1e-226	311	649
PI-PLCc_eukaryota	cd08558	4.9e-184	311	649
PI-PLCc_beta	cd08591	1.7e-245	311	649
PI-PLCc_delta	cd08593	1.7e-122	311	649
PI-PLCc_eta	cd08594	1.1e-59	311	649
PI-PLCc_zeta	cd08595	4.1e-99	311	649
PI-PLCc_gamma	cd08592	3.8e-10	311	935
PI-PLCc_PRIP_metazoa	cd08597	5.2e-96	311	649
PI-PLCc_plant	cd08599	1e-53	311	649
PI-PLCc_beta1	cd08623	8.3e-185	311	649
PI-PLCc_beta2	cd08624	1.8e-264	311	649
PI-PLCc_beta3	cd08625	3.6e-179	311	649
PI-PLCc_beta4	cd08626	2.3e-150	311	649
PI-PLCc_delta1	cd08629	9.9e-96	311	649
PI-PLCc_gamma2	cd08628	4.8e-08	311	863
PI-PLCc_delta4	cd08631	1.5e-95	311	649
PI-PLCc_eta1	cd08632	1.4e-48	311	649
PI-PLCc_eta2	cd08633	7.9e-49	311	649
PI-PLC1c_yeast	cd08598	5.7e-92	311	649
PI-PLCc_epsilon	cd08596	2.2e-45	311	649
PI-PLCc_delta3	cd08630	1.3e-97	311	649
PI-PLCc_gamma1	cd08627	9.9e-05	312	1074
PI-PLCc_GDPD_SF	cd08555	2.1e-129	324	632
C2_PLC_like	cd00275	5.4e-42	681	802
C2	cd00030	1.2e-06	684	780
PI-PLC-X	pfam00388	1.1e-95	314	464
PI-PLC-Y	pfam00387	3.1e-70	545	662
C2	pfam00168	4.5e-14	684	767
efhand_like	pfam09279	9e-41	220	311
PLCXc	smart00148	5.2e-74	312	453
PLCYc	smart00149	3.1e-70	547	661
C2	smart00239	1e-16	683	782
PLC-beta_C	pfam08703	1.1e-101	976	1155

Table of Mutations found on the Protein

Source ↕	Mut_ID ↕	Class ↕	HGVS ↕	Disease ↕
Swiss-Prot	VAR_047510	Polymorphism	p.ARG598HIS	N/A
Swiss-Prot	VAR_047509	Polymorphism	p.ASN324ILE	N/A
Swiss-Prot	VAR_047513	Polymorphism	p.GLU1095GLY	N/A
Swiss-Prot	VAR_047512	Polymorphism	p.GLY712ARG	N/A
dbSNP	rs114336069	Polymorphism	p.HIS312GLN	N/A
Swiss-Prot	VAR_047511	Polymorphism	p.PRO664LEU	N/A

Please Cite: Peterson, T.A., Adadey, A., Santana-Cruz ,I., Sun, Y., Winder A, Kann, M.G., (2010) DMDM: Domain Mapping of Disease Mutations. Bioinformatics 26 (19), 2458-2459.

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