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Results for the Protein: Q12965
215274106

MYO1E_HUMAN RecName: Full=Unconventional myosin-Ie; AltName: Full=Myosin-Ic; AltName: Full=Unconventional myosin 1E

Known Diseases associated with this Protein:
  FOCAL SEGMENTAL GLOMERULOSCLEROSIS 6
  FOCAL SEGMENTAL GLOMERULOSCLEROSIS 6 (FSGS6)
3
4
2
0
5
Tips:
 The Domains on the Default View are decided by the Domain's E-Value.

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 To view the Gene page, either click on the link to the left or the blue bar above the Protein's graphic.



Default View:

COG5022 - COG5022
MYSc - smart00242
MYSc_type_VI - cd01382
MYSc_type_II - cd01377
MYSc_type_IX - cd01385
MYSc_type_XV - cd01387
MYSc_type_XI - cd01384
MYSc_type_XVIII - cd01386
MYSc_type_III - cd01379
MYSc_type_VIII - cd01383
MYSc_type_VII - cd01381
MYSc - cd00124
MYSc_type_V - cd01380
MYSc_type_I - cd01378
Myosin_head - pfam00063
Motor_domain - cd01363
Myosin_TH1 - pfam06017
SH3 - smart00326
SH3 - cd00174
SH3_2 - pfam07653
SH3_1 - pfam00018


Swiss-Prot Protein: Q12965
Identical to: NP_004989
   Default View:


















Domains found on the Protein

Domain ↕CD Accession ↕E-Value ↕Start ↕End ↕
MYSc_type_IIcd013776.9e-17715691
MYSc_type_IXcd013856.1e-7617694
MYSc_type_XIcd013841.9e-20119695
MYSc_type_XVcd013879.8e-15619691
MYSccd001241.8e-28520691
MYSc_type_Icd0137820691
MYSc_type_Vcd013805.4e-17320691
MYSc_type_VIIcd013811.9e-20820691
MYSc_type_IIIcd013792.8e-7020708
MYSc_type_VIIIcd013832e-15120691
MYSc_type_XVIIIcd013865.2e-1120691
Motor_domaincd013636.3e-3355589
SH3cd001745.5e-2410551107
COG5022COG50225.1e-15411108
Myosin_headpfam0006321679
SH3_1pfam000184.9e-1910571102
MYScsmart0024214692
Myosin_TH1pfam060179.6e-100718923
SH3smart003261.2e-2510521108
SH3_2pfam076535.4e-0910551107

Table of Mutations found on the Protein

Source ↕Mut_ID ↕Class ↕HGVS ↕Disease ↕
Swiss-ProtVAR_065958Diseasep.ALA159PROFocal segmental glomerulosclerosis 6 (FSGS6)
Swiss-ProtVAR_065960Polymorphismp.ALA221VALN/A
Swiss-ProtVAR_065959Polymorphismp.ASP185GLYN/A
Swiss-ProtVAR_065961Polymorphismp.GLY795ARGN/A
Swiss-ProtVAR_065962Polymorphismp.PRO1049HISN/A
OMIM601479.0001 Diseasep.ALA159PROFOCAL SEGMENTAL GLOMERULOSCLEROSIS 6
OMIM601479.0002 Diseasep.TYR695TERFOCAL SEGMENTAL GLOMERULOSCLEROSIS 6



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