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Results for the Protein: Q14790
2493531
841

CASP8_HUMAN RecName: Full=Caspase-8; Short=CASP-8; AltName: Full=Apoptotic cysteine protease; AltName: Full=Apoptotic protease Mch-5; AltName: Full=CAP4; AltName: Full=FADD-homologous ICE/ced-3-like protease; AltName: Full=FADD-like ICE; Short=FLICE; AltName: Full=ICE-like apoptotic protease 5; AltName: Full=MORT1-associated ced-3 homolog; Short=MACH; Contains: RecName: Full=Caspase-8 subunit p18; Contains: RecName: Full=Caspase-8 subunit p10; Flags: Precursor

Known Diseases associated with this Protein:
  BREAST CANCER, PROTECTION AGAINST
  CASPASE 8 DEFICIENCY
  CASPASE-8 DEFICIENCY (CASP8D)
3
2
2
0
3
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Default View:

DED - smart00031
CASc - smart00115


Swiss-Prot Protein: Q14790
Identical to: NP_203519
   Default View:



Domains found on the Protein

Domain ↕CD Accession ↕E-Value ↕Start ↕End ↕
DEDsmart000311.3e-32180
DEDsmart000313e-2799178
CAScsmart001159.7e-141226478

Table of Mutations found on the Protein

Source ↕Mut_ID ↕Class ↕HGVS ↕Disease ↕
Swiss-ProtVAR_014204Diseasep.ARG248TRPCaspase-8 deficiency (CASP8D)
Swiss-ProtVAR_020127Polymorphismp.ASP285HISN/A
Swiss-ProtVAR_025816Polymorphismp.SER219THRN/A
OMIM601763.0001 Diseasep.ARG189TRPCASPASE 8 DEFICIENCY
OMIM601763.0003 Diseasep.ASP243HISBREAST CANCER, PROTECTION AGAINST



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