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Results for the Protein: Q16620
2497560

NTRK2_HUMAN RecName: Full=BDNF/NT-3 growth factors receptor; AltName: Full=GP145-TrkB; Short=Trk-B; AltName: Full=Neurotrophic tyrosine kinase receptor type 2; AltName: Full=TrkB tyrosine kinase; AltName: Full=Tropomyosin-related kinase B; Flags: Precursor

Known Diseases associated with this Protein:
  OBESITY HYPERPHAGIA AND DEVELOPMENTAL DELAY (OHPDD)
  OBESITY, HYPERPHAGIA, AND DEVELOPMENTAL DELAY
2
7
1
0
8
Tips:
 The Domains on the Default View are decided by the Domain's E-Value.

 Clicking a check box will display or hide the correlated domain.

 To view the Gene page, either click on the link to the left or the blue bar above the Protein's graphic.



Default View:

LRRNT - smart00013
LRRNT - pfam01462
LRRCT - smart00082
Ig5_NCAM-1 - cd05869
Ig3_Contactin-1 - cd05851
I-set - pfam07679
Ig3_Contactin_like - cd04968
Ig_TrkABC_d4 - cd04972
Ig5_NCAM-1_like - cd05732
IG - smart00409
IG_like - smart00410
Ig2_FGFR_like - cd05729
V-set - pfam07686
IGc2 - smart00408
Ig3_Peroxidasin - cd05745
Ig_2 - cd05764
Ig - cd00096
Ig3_Robo - cd05725
Ig_TrKABC_d5 - cd04971
Ig_TrkB_d5 - cd05855
PTKc_CSF-1R - cd05106
PTKc_Kit - cd05104
PTKc_PDGFR_beta - cd05107
PTKc_PDGFR_alpha - cd05105
PTKc_PDGFR - cd05055
STKc_myosinIIIB - cd06639
STKc_myosinIIIA - cd06638
STKc_ERK5 - cd07855
PTKc_FGFR1 - cd05098
STKc_PAK6 - cd06659
PTKc_FGFR2 - cd05101
STKc_PAK_I - cd06647
STKc_PAK4 - cd06657
PTKc_EGFR_like - cd05057
PKc_MKK7 - cd06618
STKc_CDK9 - cd07865
STKc_SLK - cd06643
PTKc_FGFR - cd05053
STKc_TAO2 - cd06634
PTKc_FGFR4 - cd05099
STKc_PAK_II - cd06648
PTKc_FGFR3 - cd05100
STKc_CDK10 - cd07845
STKc_Sty1_Hog1 - cd07856
STKc_PAK - cd06614
PTK_Tyk2_rpt1 - cd05076
STKc_p38 - cd07851
STKc_ASK - cd06624
STKc_BUR1 - cd07866
STKc_CDK12 - cd07864
STKc_SLK_like - cd06611
PTKc_HER4 - cd05110
PTK_HER3 - cd05111
PTKc_HER2 - cd05109
STKc_STK10_LOK - cd06644
PTKc_EGFR - cd05108
PTKc_Tie2 - cd05088
STKc_MAPK15 - cd07852
PTKc_ALK_LTK - cd05036
PTKc_FAK - cd05056
PTKc_VEGFR3 - cd05102
PTKc_DDR_like - cd05097
PTKc_VEGFR2 - cd05103
PTKc_TrkB - cd05093
PTKc_DDR1 - cd05096
PTKc_TrkC - cd05094
PTKc_DDR2 - cd05095
PTKc_TrkA - cd05092
STKc_PFTAIRE2 - cd07870
STKc_PCTAIRE3 - cd07871
STKc_PCTAIRE_like - cd07844
STKc_MAP4K5 - cd06646
STKc_MAP4K3 - cd06645
PKc_MAPKK_Byr1_like - cd06620
PTKc_InsR - cd05061
PTKc_Trk - cd05049
PTKc_Ror - cd05048
PTK_CCK4 - cd05046
PTKc_EphR_A10 - cd05064
PTKc_Musk - cd05050
PTKc_DDR - cd05051
PTKc_Ror2 - cd05091
PTKc_EphR_A2 - cd05063
PTKc_VEGFR - cd05054
PTKc_Abl - cd05052
PTKc_Frk_like - cd05068
PTKc_Lck_Blk - cd05067
PTKc_Tyk2_rpt2 - cd05080
PTKc_Jak2_Jak3_rpt2 - cd05081
PTKc_Csk - cd05082
PTKc_Ror1 - cd05090
PTKc_Hck - cd05073
PTKc_IGF-1R - cd05062
PTKc_Yes - cd05069
PTKc_Src - cd05071
PTKc_Fyn_Yrk - cd05070
PTKc_Lyn - cd05072
PTKc_Tec_Rlk - cd05114
PKc_MKK4 - cd06616
PTKc_Btk_Bmx - cd05113
PTKc_EphR_A - cd05066
PTKc_InsR_like - cd05032
PTK_Ryk - cd05043
PTKc_Itk - cd05112
PTKc_EphR_B - cd05065
PTKc_Csk_like - cd05039
PTKc_Jak_rpt2 - cd05038
PTKc_Chk - cd05083
PTKc_Jak1_rpt2 - cd05079
PTKc_EphR - cd05033
PTKc_Src_like - cd05034
PTKc_Tec_like - cd05059
STKc_PCTAIRE2 - cd07872
STKc_MST4 - cd06640
STKc_MAP4K3_like - cd06613
STKc_MST3 - cd06641
STKc_STK25-YSK1 - cd06642
STKc_CDKL1_4 - cd07847
STKc_CDKL2_3 - cd07846
STKc_Nek6_Nek7 - cd08224
STKc_MEKK3_like_1 - cd06653
STKc_CDK5 - cd07839
STKc_ERK1_2_like - cd07849
STKc_MPK1 - cd07857
STKc_MEKK2 - cd06652
STKc_CDK8_like - cd07842
STKc_CDK4 - cd07863
STKc_phototropin_lik - cd05574
PTKc_Srm_Brk - cd05148
STKc_CDK1_like - cd07835
STKc_Nek6 - cd08228
PTKc_Tie1 - cd05089
STKc_MOK - cd07831
SPS1 - COG0515
STKc_Nek7 - cd08229
PKc_MEK - cd06615
PKc_MKK3_6 - cd06617
STKc_MAPKKK_Bck1_lik - cd06629
STKc_PRKX_like - cd05612
STKc_PKA - cd05580
STKc_PDK1 - cd05581
PKc_MKK5 - cd06619
PKc_MAPKK - cd06605
PKc_MAPKK_plant_like - cd06623
STKc_MEKK3_like - cd06625
PKc_MAPKK_PBS2_like - cd06622
PKc_MAPKK_Pek1_like - cd06621
STKc_MST3_like - cd06609
STKc_Nek4 - cd08223
STKc_Nek3 - cd08219
STKc_Nek11 - cd08222
STKc_Nek10 - cd08528
STKc_Nek1 - cd08218
STKc_FA2-like - cd08529
STKc_Nek8 - cd08220
STKc_Nek5 - cd08225
STKc_CDK7 - cd07841
STKc_GRK4_like - cd05605
STKc_MAPKKK_Byr2_lik - cd06628
PTKc_RET - cd05045
STKc_Nek - cd08215
STKc_MSK_N - cd05583
STKc_Yank1 - cd05578
STKc_Cdc7_like - cd06627
STKc_MAPKKK - cd06606
STKc_Pho85 - cd07836
STKc_CDK2_3 - cd07860
STKc_CDK1_euk - cd07861
STKc_MSK1_N - cd05613
STKc_MAPK - cd07834
STKc_MEKK3 - cd06651
STKc_CCRK - cd07832
TyrKc - smart00219
Pkinase_Tyr - pfam07714
Pkinase - pfam00069
PTKc_Axl_like - cd05035
PTKc_Axl - cd05075
PTKc_Tyro3 - cd05074
STKc_CNK2-like - cd08530
STYKc - smart00221
STKc_CDK4_6_like - cd07838
STKc_ROCK_NDR_like - cd05573
STKc_MAK_like - cd07830
STKc_CDK9_like - cd07840
PK_STRAD - cd08216
STKc_myosinIII_like - cd06608
STKc_Nek2 - cd08217
STKc_MEKK4 - cd06626
STKc_OSR1_SPAK - cd06610
PKc_STE - cd05122
STKc_RSK_N - cd05582
STKc_NAK1_like - cd06917
STKc_CDK_like - cd07829
PTKc_Aatyk - cd05042
PTKc_Fes_like - cd05041
PTK_Jak_rpt1 - cd05037
PTKc_Ack_like - cd05040
PTKc - cd00192
STKc_MEKK1 - cd06630
PTKc_c-ros - cd05044
STKc_Nek9 - cd08221
PTKc_Fes - cd05084
PTKc_Aatyk2 - cd05086
PTKc_Aatyk1_Aatyk3 - cd05087
PTK_Jak2_Jak3_rpt1 - cd05078
PTK_Jak1_rpt1 - cd05077
PTKc_Met_Ron - cd05058
PTKc_Syk_like - cd05060
PTKc_Syk - cd05116
STKc_CMGC - cd05118
STKc_MEKK1_plant - cd06632
STKc_nPKC_theta_delt - cd05592
STKc_nPKC_theta - cd05619
STKc_PKC - cd05570
PTKc_Zap-70 - cd05115
STKc_CDKL - cd07833
STKc_CdkB_plant - cd07837
STKc_CDC2L1 - cd07843
PTKc_Tie - cd05047
STKc_AGC - cd05123
PTKc_Fer - cd05085
PKc - cd00180
STKc_cGK_PKG - cd05572
STKc_GRK - cd05577
STKc_MST1_2 - cd06612
STKc_YSK4 - cd06631
STKc_GRK1 - cd05608
STKc_MAST_like - cd05579
S_TKc - smart00220


Swiss-Prot Protein: Q16620
Identical to: NP_001018074
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Domains found on the Protein

Domain ↕CD Accession ↕E-Value ↕Start ↕End ↕
Ig5_NCAM-1cd058690.0007195283
Ig3_Contactin-1cd058510.0007196284
Ig3_Contactin_likecd049685.7e-05197284
Ig_TrkABC_d4cd049721.9e-10198283
Ig5_NCAM-1_likecd057320.00058202283
Ig2_FGFR_likecd057290.00067203283
Ig3_Peroxidasincd057450.00011210283
Ig_2cd057643.1e-05211283
Igcd000963.1e-08214280
Ig3_Robocd057251.7e-05214283
Ig_TrKABC_d5cd049718.3e-57301379
Ig_TrkB_d5cd058551.1e-57301379
PTKc_CSF-1Rcd051063e-37500812
PTKc_Kitcd051041.9e-25503811
PTKc_PDGFR_alphacd051053.9e-17506813
PTKc_PDGFR_betacd051073e-19506812
PTKc_PDGFRcd050556.3e-24507811
STKc_myosinIIIBcd066394.2e-05516812
STKc_myosinIIIAcd066385.6e-06517807
STKc_ERK5cd078550.00074517818
PTKc_FGFR1cd050984.8e-57518817
STKc_PAK6cd066591.5e-05519816
PTKc_FGFR2cd051011.5e-53521811
PTKc_EGFR_likecd050579.8e-57522821
STKc_PAK4cd066570.00091522802
STKc_PAK_Icd066470.00092522822
PKc_MKK7cd066181.2e-05523819
STKc_CDK9cd078651.3e-05523821
PTKc_FGFRcd050535.8e-64524811
STKc_SLKcd066439.7e-08524813
STKc_TAO2cd066340.00021525820
PTKc_FGFR4cd050996.8e-60526820
PTKc_FGFR3cd051001.8e-41526820
STKc_PAK_IIcd066481.7e-07526821
PTK_Tyk2_rpt1cd050761.1e-06528811
STKc_PAKcd066141.1e-12528821
STKc_CDK10cd078455.7e-07528819
STKc_Sty1_Hog1cd078560.00022528819
STKc_ASKcd066243.4e-07529812
STKc_p38cd078516.5e-05529812
STKc_CDK12cd078642.7e-08529821
STKc_BUR1cd078664.3e-10529799
PTKc_Tie2cd050881.9e-44530820
PTKc_EGFRcd051085.5e-22530822
PTKc_HER2cd051093.3e-39530821
PTK_HER3cd051117.3e-38530821
PTKc_HER4cd051109.2e-24530822
STKc_SLK_likecd066111.8e-09530809
STKc_STK10_LOKcd066448.7e-07530817
PTKc_ALK_LTKcd050369.5e-87531809
PTKc_FAKcd050562.2e-78531815
STKc_MAPK15cd078525.5e-06531820
PTK_CCK4cd050461.7e-75532809
PTKc_Rorcd050484.6e-120532810
PTKc_Trkcd050494.1e-238532809
PTKc_Muskcd050503.4e-135532809
PTKc_DDRcd050511.1e-106532809
PTKc_Ablcd050529.5e-72532811
PTKc_VEGFRcd050542.8e-31532814
PTKc_InsRcd050612.4e-83532820
PTKc_EphR_A2cd050636.2e-66532811
PTKc_EphR_A10cd050642.3e-59532811
PTKc_Lck_Blkcd050672.1e-52532810
PTKc_Frk_likecd050681.8e-76532810
PTKc_Yescd050698.4e-45532810
PTKc_Fyn_Yrkcd050706.9e-50532810
PTKc_Srccd050711.2e-46532812
PTKc_Lyncd050722.3e-55532810
PTKc_Hckcd050731.8e-54532810
PTKc_IGF-1Rcd050621.5e-80532809
PTKc_Tyk2_rpt2cd050803.8e-45532812
PTKc_Jak2_Jak3_rpt2cd050811.9e-48532811
PTKc_Cskcd050824.1e-49532810
PTKc_Ror1cd050901e-92532810
PTKc_Ror2cd050919.6e-86532810
PTKc_TrkAcd050925.4e-205532809
PTKc_TrkBcd050932.3e-279532819
PTKc_TrkCcd050941.4e-209532819
PTKc_DDR2cd050959.9e-92532809
PTKc_DDR_likecd050975.1e-92532809
PTKc_VEGFR3cd051023.5e-36532814
PTKc_VEGFR2cd051034.4e-29532814
PTKc_DDR1cd050964e-85532809
PKc_MAPKK_Byr1_likecd066204.7e-09532822
STKc_MAP4K3cd066455.5e-05532811
STKc_MAP4K5cd066460.00032532814
STKc_PCTAIRE_likecd078442e-05532821
STKc_PFTAIRE2cd078700.00028532818
STKc_PCTAIRE3cd078713.3e-05532818
PTKc_EphRcd050332.6e-75533811
PTKc_Src_likecd050346.8e-69533810
PTKc_Jak_rpt2cd050389.9e-67533811
PTKc_Csk_likecd050392.7e-35533813
PTKc_InsR_likecd050321.3e-103533809
PTK_Rykcd050436.1e-27533810
PTKc_Tec_likecd050594.2e-72533811
PTKc_EphR_Bcd050654.7e-62533811
PTKc_EphR_Acd050661.5e-68533811
PTKc_Jak1_rpt2cd050795.3e-42533811
PTKc_Chkcd050839.3e-58533810
PTKc_Itkcd051122.6e-69533811
PTKc_Btk_Bmxcd051131.1e-69533808
PTKc_Tec_Rlkcd051143.9e-66533808
PKc_MKK4cd066167.5e-06533821
STKc_MAP4K3_likecd066132.2e-09534806
STKc_MST4cd066405.8e-06534821
STKc_MST3cd066412.4e-06534821
STKc_STK25-YSK1cd066421.7e-06534822
STKc_CDKL2_3cd078466.9e-06534821
STKc_CDKL1_4cd078474.8e-05534821
STKc_PCTAIRE2cd078720.00059534816
PTKc_Srm_Brkcd051482.5e-62535810
STKc_phototropin_likcd055740.00013535817
STKc_MEKK2cd066527.9e-07535808
STKc_MEKK3_like_1cd066533.8e-08535812
STKc_CDK8_likecd078421.7e-05535797
STKc_CDK5cd078391.1e-06535818
STKc_ERK1_2_likecd078490.00013535822
STKc_MPK1cd078570.00062535820
STKc_CDK4cd078630.00016535811
STKc_Nek6_Nek7cd082241.2e-09535816
PTKc_Tie1cd050892e-48536819
STKc_PKAcd055804.1e-05536813
STKc_PDK1cd055818.2e-12536807
STKc_PRKX_likecd056122.8e-05536818
PKc_MAPKKcd066058.6e-08536812
PKc_MEKcd066151.2e-05536821
PKc_MKK3_6cd066171.1e-05536822
PKc_MKK5cd066190.00016536822
PKc_MAPKK_Pek1_likecd066212.2e-07536804
STKc_MST3_likecd066092.6e-09536818
PKc_MAPKK_PBS2_likecd066221.2e-05536821
PKc_MAPKK_plant_likecd066231e-13536805
STKc_MEKK3_likecd066251.4e-12536812
STKc_MAPKKK_Bck1_likcd066297e-11536800
STKc_MOKcd078314.6e-05536822
STKc_CDK1_likecd078352.8e-07536818
STKc_Nek6cd082288.9e-08536812
STKc_Nek7cd082291.9e-09536812
SPS1COG05153.4e-08536822
PTKc_RETcd050457e-55537814
STKc_Yank1cd055781.9e-08537818
STKc_MSK_Ncd055833.1e-05537819
STKc_GRK4_likecd056059.7e-05537820
STKc_MSK1_Ncd056130.00025537820
STKc_MAPKKKcd066061.7e-19537807
STKc_MAPKKK_Byr2_likcd066281.3e-14537807
STKc_Cdc7_likecd066271.5e-14537807
STKc_MEKK3cd066512.3e-10537809
STKc_CCRKcd078327.3e-10537799
STKc_MAPKcd078342.9e-08537814
STKc_Pho85cd078364.8e-06537817
STKc_CDK7cd078413.8e-09537811
STKc_CDK2_3cd078600.00015537818
STKc_CDK1_eukcd078613.5e-05537818
STKc_Nekcd082153.4e-17537809
STKc_Nek1cd082189.8e-08537811
STKc_Nek3cd082192.8e-10537807
STKc_Nek11cd082221.6e-13537811
STKc_Nek4cd082233.2e-11537811
STKc_Nek5cd082257.7e-09537807
STKc_Nek8cd082209e-07537811
STKc_Nek10cd085282.2e-05537809
STKc_FA2-likecd085291e-11537812
PTKc_Axl_likecd050352.5e-62538811
PTKc_Axlcd050754.9e-55538814
PTKc_Tyro3cd050741e-61538811
STKc_CNK2-likecd085301.2e-09538807
STKc_ROCK_NDR_likecd055730.00032539822
STKc_MAK_likecd078301.1e-10539807
STKc_CDK4_6_likecd078381.8e-06539797
STKc_CDK9_likecd078402.6e-12539821
PK_STRADcd082160.00052539813
PKc_STEcd051221.8e-13540800
STKc_myosinIII_likecd066083.8e-07540786
STKc_OSR1_SPAKcd066102.9e-09540800
STKc_MEKK4cd066264.1e-11540800
STKc_Nek2cd082172.5e-08540807
STKc_RSK_Ncd055820.00077541820
STKc_NAK1_likecd069171.8e-08541818
STKc_CDK_likecd078293.3e-12541807
PTKccd001922.7e-142542808
PTKc_Ack_likecd050405.2e-70542809
PTKc_Fes_likecd050411.3e-56542809
PTKc_Aatykcd050422.4e-34542809
PTKc_c-roscd050441.7e-90542809
PTK_Jak_rpt1cd050379e-13542808
PTKc_Met_Roncd050588.2e-67542813
PTKc_Syk_likecd050603.7e-61542812
PTK_Jak1_rpt1cd050779.6e-10542808
PTK_Jak2_Jak3_rpt1cd050786e-13542808
PTKc_Fescd050844.5e-64542809
PTKc_Aatyk2cd050867.8e-40542809
PTKc_Aatyk1_Aatyk3cd050873.5e-46542809
PTKc_Sykcd051163.1e-52542812
STKc_CMGCcd051184.1e-11542807
STKc_PKCcd055701.1e-05542821
STKc_nPKC_theta_deltcd055920.00032542822
STKc_nPKC_thetacd056190.00013542815
STKc_MEKK1_plantcd066322.3e-12542807
STKc_MEKK1cd066302.2e-07542808
STKc_Nek9cd082212.2e-08542806
PTKc_Zap-70cd051152.2e-53543812
STKc_CDKLcd078331.5e-06543807
STKc_CdkB_plantcd078371.2e-07543819
STKc_CDC2L1cd078432.1e-06543818
PKccd001803e-62544810
PTKc_Tiecd050472.4e-54544812
PTKc_Fercd050853.9e-54544809
STKc_AGCcd051234.5e-09544817
STKc_cGK_PKGcd055725.6e-08544814
STKc_GRKcd055770.00087544819
STKc_MAST_likecd055797.5e-09544805
STKc_GRK1cd056080.00014544819
STKc_MST1_2cd066127.4e-10544800
STKc_YSK4cd066313.7e-09544807
LRRNTpfam014625.1e-083160
Pkinasepfam000697.9e-43538810
LRRNTsmart000131.7e-073165
LRRCTsmart000829.5e-09148195
I-setpfam076796.3e-10197283
IGsmart004097.9e-14203284
IG_likesmart004107.9e-14203284
V-setpfam076860.0008205283
IGc2smart004084.1e-08210273
Pkinase_Tyrpfam077141.6e-148538807
TyrKcsmart002191.1e-137538807
STYKcsmart002211.8e-59538809
S_TKcsmart002205.4e-51548817

Table of Mutations found on the Protein

Source ↕Mut_ID ↕Class ↕HGVS ↕Disease ↕
Swiss-ProtVAR_046520Polymorphismp.ARG718CYSN/A
Swiss-ProtVAR_046519Polymorphismp.ARG699GLYN/A
Swiss-ProtVAR_011973Polymorphismp.ASN338TYRN/A
Swiss-ProtVAR_016320Polymorphismp.GLY309ARGN/A
Swiss-ProtVAR_049715Polymorphismp.GLY545VALN/A
Swiss-ProtVAR_041470Polymorphismp.LEU138PHEN/A
Swiss-ProtVAR_046518Polymorphismp.MET697ILEN/A
Swiss-ProtVAR_065890Diseasep.TYR706CYSObesity hyperphagia and developmental delay (OHPDD)
OMIM600456.0001 Diseasep.TYR706CYSOBESITY, HYPERPHAGIA, AND DEVELOPMENTAL DELAY



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