Results for the protein: P49916

Results for the Protein: P49916

251757259

3980

LIG3

NCBI, UniProt

DNLI3_HUMAN RecName: Full=DNA ligase 3; AltName: Full=DNA ligase III; AltName: Full=Polydeoxyribonucleotide synthase [ATP] 3

			0 5 0 1 4

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Swiss-Prot Protein: P49916

Identical to: NP_039269

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Domains found on the Protein

Domain ↕	CD Accession ↕	E-Value ↕	Start ↕	End ↕
Adenylation_DNA_liga	cd07902	4e-186	468	680
Adenylation_DNA_liga	cd07903	8.2e-30	470	682
Adenylation_DNA_liga	cd07900	1.1e-28	472	680
Adenylation_DNA_liga	cd07901	1.3e-28	477	679
Adenylation_DNA_liga	cd06846	1.4e-10	480	678
Adenylation_DNA_liga	cd07897	1.4e-07	480	681
Adenylation_kDNA_lig	cd07896	0.00074	481	678
Adenylation_DNA_liga	cd07898	9.3e-102	481	679
Adenylation_DNA_liga	cd07906	2.6e-12	481	679
	cd07907	3.1e-10	481	680
Adenylation_DNA_liga	cd07905	1.4e-06	481	680
Adenylation_DNA_liga	cd08039	0.00028	481	679
OBF_DNA_ligase_III	cd07967	1.3e-114	686	824
OBF_DNA_ligase_IV	cd07968	5e-13	687	822
OBF_DNA_ligase_I	cd07969	6.7e-22	687	831
OBF_DNA_ligase	cd07893	4.7e-76	688	819
OBF_DNA_ligase_Arch_	cd07972	2.7e-10	688	827
OBF_DNA_ligase_famil	cd08040	0.00038	688	811
BRCT	cd00027	0.00011	940	1001
zf-PARP	pfam00645	2.6e-37	96	182
DNA_ligase_A_N	pfam04675	1.9e-49	261	435
DNA_ligase_A_M	pfam01068	1e-90	483	677
DNA_ligase_A_C	pfam04679	3.8e-26	704	814
BRCT	smart00292	8.1e-07	936	1003

Table of Mutations found on the Protein

Source ↕	Mut_ID ↕	Class ↕	HGVS ↕	Disease ↕
dbSNP	rs3136025	Polymorphism	p.ARG867HIS	N/A
Swiss-Prot	VAR_020196	Polymorphism	p.ARG224TRP	N/A
Swiss-Prot	VAR_036513	Polymorphism	p.ASP717ASN	N/A
Swiss-Prot	VAR_021938	Polymorphism	p.LYS898THR	N/A
Swiss-Prot	VAR_020197	Polymorphism	p.PRO986SER	N/A

Please Cite: Peterson, T.A., Adadey, A., Santana-Cruz ,I., Sun, Y., Winder A, Kann, M.G., (2010) DMDM: Domain Mapping of Disease Mutations. Bioinformatics 26 (19), 2458-2459.

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