Results for the protein: P08581

Domains found on the Protein

Domain ↕	CD Accession ↕	E-Value ↕	Start ↕	End ↕
IPT_PCSR	cd00603	2.1e-25	563	656
IPT_plexin_repeat1	cd01180	6.8e-44	563	656
IPT	cd00102	7.8e-20	657	740
IPT_PCSR	cd00603	3.2e-25	657	740
IPT_plexin_repeat2	cd01179	1.2e-37	657	740
IPT_plexin_repeat1	cd01180	7.9e-07	657	740
IPT	cd00102	2.6e-10	742	837
IPT_PCSR	cd00603	1.2e-14	742	837
IPT_plexin_repeat3	cd01181	1.5e-44	742	837
IPT_PCSR	cd00603	0.00074	839	935
PTKc_VEGFR	cd05054	6.3e-38	954	1344
PTKc_PDGFR_alpha	cd05105	5.8e-16	982	1343
PTKc_PDGFR_beta	cd05107	5.7e-17	982	1342
STKc_ROCK2	cd05621	0.00049	1035	1358
PTKc_CSF-1R	cd05106	5.4e-21	1037	1342
STKc_TAO1	cd06635	0.00046	1049	1365
PTKc_Kit	cd05104	6.2e-18	1051	1341
STKc_MAP4K3	cd06645	0.00068	1054	1338
STKc_myosinIIIB	cd06639	4e-05	1055	1340
PTKc_FGFR1	cd05098	8.3e-46	1056	1348
PTKc_FGFR4	cd05099	4.5e-46	1057	1362
STKc_PAK5	cd06658	0.00087	1057	1334
STKc_PAK6	cd06659	0.00012	1058	1363
PTKc_FGFR2	cd05101	5.5e-43	1059	1348
STKc_TAO	cd06607	0.00013	1059	1365
STKc_TAO2	cd06634	0.00014	1059	1366
STKc_PAK_I	cd06647	1.4e-05	1059	1360
STKc_PAK1	cd06654	1.3e-05	1059	1358
STKc_PAK2	cd06655	3.3e-05	1059	1359
STKc_PAK3	cd06656	1.7e-05	1059	1364
STKc_PAK4	cd06657	0.00092	1059	1336
STKc_PAK_II	cd06648	1.1e-06	1059	1344
PTK_Tyk2_rpt1	cd05076	6e-05	1060	1338
STKc_PAK	cd06614	8.1e-11	1060	1345
STKc_myosinIIIA	cd06638	4.5e-07	1060	1339
STKc_MAP4K4_6	cd06636	0.00038	1061	1340
PKc_MKK7	cd06618	1.9e-06	1061	1371
PTKc_PDGFR	cd05055	2e-20	1062	1341
PTKc_FGFR3	cd05100	2.5e-43	1063	1383
STKc_STK10_LOK	cd06644	0.00013	1066	1357
PTKc_Tie2	cd05088	1.4e-43	1068	1361
PTKc_ALK_LTK	cd05036	5.5e-70	1069	1339
PTKc_EGFR_like	cd05057	5.1e-74	1069	1353
PTKc_Chk	cd05083	6.2e-55	1069	1340
STKc_ASK	cd06624	1.6e-06	1069	1339
PTKc_DDR	cd05051	1.1e-45	1070	1339
STKc_Sty1_Hog1	cd07856	0.00091	1070	1389
STKc_BUR1	cd07866	1.1e-09	1070	1341
PTKc_EphR	cd05033	3.4e-60	1071	1341
PTKc_Src_like	cd05034	1.1e-67	1071	1340
PTKc_InsR_like	cd05032	2.2e-85	1071	1339
PTK_Ryk	cd05043	7.4e-60	1071	1344
PTKc_Abl	cd05052	7.5e-70	1071	1341
PTKc_FAK	cd05056	9.7e-71	1071	1345
PTKc_Tec_like	cd05059	5.7e-60	1071	1338
PTKc_EphR_A2	cd05063	5.7e-55	1071	1341
PTKc_EphR_B	cd05065	1.4e-59	1071	1341
PTKc_EphR_A	cd05066	2.3e-60	1071	1341
PTKc_Lck_Blk	cd05067	3.8e-45	1071	1340
PTKc_Yes	cd05069	1.2e-37	1071	1340
PTKc_Fyn_Yrk	cd05070	1.7e-43	1071	1340
PTKc_Hck	cd05073	1.2e-46	1071	1340
PTKc_Src	cd05071	5e-43	1071	1342
PTKc_TrkA	cd05092	2.1e-46	1071	1339
PTKc_Itk	cd05112	9.8e-62	1071	1338
PTKc_Tec_Rlk	cd05114	3.3e-65	1071	1338
PTKc_Btk_Bmx	cd05113	3e-64	1071	1338
STKc_TNIK	cd06637	7.4e-05	1071	1339
STKc_PCTAIRE_like	cd07844	1.4e-05	1071	1373
STKc_TEY_MAPK_plant	cd07858	0.00033	1071	1390
STKc_PCTAIRE3	cd07871	4.8e-05	1071	1350
STKc_PFTAIRE2	cd07870	6.4e-05	1071	1356
STKc_PCTAIRE2	cd07872	3.1e-05	1071	1360
STKc_MST4	cd06640	8e-07	1072	1360
STKc_MST3	cd06641	1.2e-07	1072	1360
STKc_STK25-YSK1	cd06642	3e-08	1072	1360
STKc_CDK10	cd07845	1.1e-06	1072	1366
STKc_PCTAIRE1	cd07873	0.00015	1072	1354
SPS1	COG0515	9.7e-09	1072	1390
PTKc_InsR	cd05061	5.1e-58	1073	1350
PTKc_Ror1	cd05090	2.2e-41	1073	1340
PTKc_DDR2	cd05095	5.2e-45	1073	1339
PTKc_DDR1	cd05096	1.2e-40	1073	1339
PTKc_Csk_like	cd05039	1.2e-51	1074	1340
PTKc_IGF-1R	cd05062	2.1e-60	1074	1339
PTKc_EphR_A10	cd05064	5.6e-45	1074	1341
PTKc_Frk_like	cd05068	2.7e-67	1074	1340
PTKc_Lyn	cd05072	4.2e-48	1074	1340
PTKc_Csk	cd05082	5.1e-54	1074	1340
PTKc_Ror2	cd05091	6.2e-33	1074	1340
PTKc_VEGFR3	cd05102	2.1e-34	1074	1344
STKc_PKA	cd05580	3.7e-05	1074	1344
STKc_MAP4K3_like	cd06613	2.4e-08	1074	1338
STKc_MST1_2	cd06612	1.9e-11	1074	1345
PKc_MAPKK_plant_like	cd06623	3.9e-09	1074	1339
STKc_MAPK4_6	cd07854	0.00017	1074	1390
STKc_CDK12	cd07864	1e-06	1074	1345
PTKc_Jak_rpt2	cd05038	7.7e-60	1075	1341
PTK_HER3	cd05111	7.2e-48	1075	1353
STKc_MEKK3	cd06651	3.8e-07	1075	1341
STKc_MEKK3_like_1	cd06653	3.2e-05	1075	1340
PKc_MAPKK_PBS2_like	cd06622	0.001	1075	1390
PTKc_Jak1_rpt2	cd05079	6e-36	1076	1341
STKc_MAPKKK	cd06606	5.9e-19	1076	1334
STKc_MST3_like	cd06609	8.3e-08	1076	1352
STKc_ERK5	cd07855	0.00013	1076	1382
PTKc_TrkB	cd05093	8e-47	1077	1343
PTKc_TrkC	cd05094	5.1e-24	1077	1351
PTKc_HER2	cd05109	1.2e-57	1077	1353
PTKc_HER4	cd05110	1e-50	1077	1373
PTKc_EGFR	cd05108	5.1e-51	1077	1383
PKc_STE	cd05122	2.6e-13	1077	1333
STKc_GRK4_like	cd05605	1.9e-05	1077	1381
STKc_GRK5	cd05632	0.0003	1077	1366
STKc_GRK4	cd05631	0.00019	1077	1366
STKc_myosinIII_like	cd06608	1.2e-08	1077	1337
STKc_CDK8_like	cd07842	7.7e-05	1077	1341
STKc_CDK9_like	cd07840	6.2e-10	1077	1345
STKc_NLK	cd07853	5.3e-05	1077	1368
STKc_Nek4	cd08223	1.6e-05	1077	1340
STKc_Nek6_Nek7	cd08224	2.3e-07	1077	1343
PTKc_Axl_like	cd05035	3.3e-107	1078	1341
PTKc_Trk	cd05049	7.8e-57	1078	1339
PTKc_Musk	cd05050	1.3e-49	1078	1339
PTKc_Ror	cd05048	2e-48	1078	1340
PTKc_FGFR	cd05053	4.5e-67	1078	1342
PTKc_RET	cd05045	1.9e-56	1078	1344
PTKc_Tyro3	cd05074	5.1e-90	1078	1341
PTKc_Axl	cd05075	1.7e-80	1078	1341
PTKc_Tyk2_rpt2	cd05080	2.3e-23	1078	1342
PTKc_Jak2_Jak3_rpt2	cd05081	6.6e-41	1078	1341
PTKc_Tie1	cd05089	1.4e-46	1078	1360
PTKc_DDR_like	cd05097	3e-47	1078	1339
PTKc_VEGFR2	cd05103	1.4e-31	1078	1344
STKc_cPKC	cd05587	0.00057	1078	1388
STKc_PKN	cd05589	1.4e-06	1078	1382
STKc_PRKX_like	cd05612	2.1e-06	1078	1380
STKc_cPKC_beta	cd05616	0.00034	1078	1388
STKc_SLK_like	cd06611	6.5e-07	1078	1347
STKc_CDK1_like	cd07835	7.1e-07	1078	1368
STKc_TDY_MAPK_plant	cd07859	0.00078	1078	1388
STKc_CDK6	cd07862	0.00025	1078	1373
STKc_Nek3	cd08219	8.8e-09	1078	1339
STKc_Nek5	cd08225	1.8e-06	1078	1339
STKc_Nek6	cd08228	1.4e-06	1078	1343
STKc_Nek7	cd08229	8.6e-08	1078	1339
PTK_CCK4	cd05046	6.7e-46	1079	1339
PTKc_Srm_Brk	cd05148	1e-50	1079	1340
STKc_PDK1	cd05581	3.3e-10	1079	1341
STKc_Yank1	cd05578	1.3e-07	1079	1340
STKc_OSR1_SPAK	cd06610	1.2e-09	1079	1340
STKc_Cdc7_like	cd06627	8.5e-13	1079	1334
STKc_SLK	cd06643	1.7e-05	1079	1354
STKc_MEKK2	cd06652	0.00037	1079	1340
STKc_CCRK	cd07832	5.8e-07	1079	1346
STKc_Pho85	cd07836	8.6e-05	1079	1357
STKc_CDK7	cd07841	2.9e-09	1079	1334
STKc_CDKL1_4	cd07847	0.00082	1079	1380
STKc_CDK2_3	cd07860	1.1e-05	1079	1368
STKc_CDK4	cd07863	0.0002	1079	1361
STKc_CDK1_euk	cd07861	6.1e-05	1079	1368
STKc_Nek9	cd08221	7.9e-06	1079	1339
STKc_Nek1	cd08218	0.00024	1079	1339
PK_STRAD	cd08216	0.0004	1079	1347
STKc_CNK2-like	cd08530	1.4e-06	1079	1339
STKc_Nek10	cd08528	4.2e-07	1079	1339
STKc_MAPKKK_Bck1_lik	cd06629	1.9e-10	1080	1308
STKc_MAPK	cd07834	6e-06	1080	1388
STKc_CDK4_6_like	cd07838	1.4e-06	1080	1341
STKc_Nek11	cd08222	1.4e-06	1080	1340
STKc_RSK_N	cd05582	9.2e-05	1081	1387
STKc_p70S6K	cd05584	5.9e-05	1081	1385
PKc_MKK4	cd06616	4.8e-06	1081	1362
STKc_MAPKKK_Byr2_lik	cd06628	6.8e-12	1081	1339
STKc_MEKK4	cd06626	8.7e-06	1081	1334
STKc_FA2-like	cd08529	4.6e-08	1081	1340
PTKc	cd00192	2.1e-142	1082	1338
PTK_Jak_rpt1	cd05037	2.8e-08	1082	1338
PTKc_Ack_like	cd05040	5.7e-53	1082	1339
PTKc_Fes_like	cd05041	3.8e-62	1082	1339
PTKc_Aatyk	cd05042	2.3e-17	1082	1336
PTKc_c-ros	cd05044	3.4e-77	1082	1339
PTKc_Met_Ron	cd05058	5.7e-196	1082	1343
PTKc_Syk_like	cd05060	8.4e-65	1082	1342
PTK_Jak1_rpt1	cd05077	3.4e-08	1082	1338
PTK_Jak2_Jak3_rpt1	cd05078	4.9e-09	1082	1338
PTKc_Fes	cd05084	1.3e-61	1082	1339
PTKc_Fer	cd05085	9.8e-59	1082	1339
PTKc_Aatyk1_Aatyk3	cd05087	5.2e-24	1082	1339
PTKc_Aatyk2	cd05086	2.6e-24	1082	1340
PTKc_Tie	cd05047	3.4e-50	1082	1342
STKc_CMGC	cd05118	3.2e-08	1082	1341
PTKc_Syk	cd05116	5.1e-51	1082	1342
STKc_PKC	cd05570	3.2e-07	1082	1350
STKc_PKB	cd05571	5.2e-06	1082	1390
STKc_SGK	cd05575	0.00028	1082	1389
STKc_nPKC_epsilon	cd05591	9.7e-05	1082	1388
STKc_nPKC_theta_delt	cd05592	2e-05	1082	1389
STKc_PKB_gamma	cd05593	5.2e-05	1082	1388
STKc_PKB_alpha	cd05594	0.00018	1082	1390
STKc_PKB_beta	cd05595	0.00056	1082	1390
STKc_SGK2	cd05603	0.0003	1082	1388
STKc_aPKC_zeta	cd05617	0.0007	1082	1390
STKc_nPKC_theta	cd05619	3.2e-05	1082	1364
PKc_MAPKK	cd06605	4.1e-05	1082	1342
STKc_MEKK3_like	cd06625	3.4e-09	1082	1339
STKc_MEKK1	cd06630	2.9e-06	1082	1342
STKc_YSK4	cd06631	2.2e-08	1082	1339
STKc_MEKK1_plant	cd06632	3e-10	1082	1334
STKc_NAK1_like	cd06917	1.3e-08	1082	1353
STKc_CDK_like	cd07829	9.4e-09	1082	1342
STKc_MAK_like	cd07830	1.8e-05	1082	1341
STKc_CdkB_plant	cd07837	3.3e-06	1082	1367
STKc_CDK5	cd07839	7.3e-06	1082	1350
STKc_CDC2L1	cd07843	2.9e-05	1082	1341
STKc_Nek	cd08215	1.1e-12	1082	1339
STKc_Nek2	cd08217	1.6e-07	1082	1337
STKc_Nek8	cd08220	3.4e-05	1082	1339
STKc_beta_ARK	cd05606	6.5e-05	1083	1371
STKc_GRK3	cd05633	0.00033	1083	1365
PKc	cd00180	1.3e-57	1084	1337
PTKc_Zap-70	cd05115	3.9e-52	1084	1342
STKc_AGC	cd05123	6e-09	1084	1341
STKc_cGK_PKG	cd05572	1.2e-06	1084	1348
STKc_GRK	cd05577	3.6e-06	1084	1347
STKc_MAST_like	cd05579	2e-06	1084	1320
STKc_YPK1_like	cd05585	0.00013	1084	1387
STKc_GRK1	cd05608	7.3e-06	1084	1364
STKc_GRK7	cd05607	6.8e-05	1084	1364
PKc_MKK3_6	cd06617	5.9e-06	1110	1339
PKc_MAPKK_Byr1_like	cd06620	0.00015	1110	1354
Sema	pfam01403	1.7e-170	55	500
PSI	pfam01437	7e-12	519	562
TIG	pfam01833	7.3e-16	563	654
TIG	pfam01833	1.8e-14	657	738
TIG	pfam01833	2.9e-09	742	835
Pkinase	pfam00069	7.6e-39	1078	1337
Sema	smart00630	2.1e-145	52	487
PSI	smart00423	5.1e-09	520	562
IPT	smart00429	2e-19	562	655
IPT	smart00429	1.8e-19	656	739
IPT	smart00429	1.2e-22	741	836
IPT	smart00429	1.1e-08	838	934
Pkinase_Tyr	pfam07714	3.5e-143	1078	1337
STYKc	smart00221	2.6e-49	1078	1339
TyrKc	smart00219	1.9e-133	1078	1337
S_TKc	smart00220	4.8e-42	1088	1341

Table of Mutations found on the Protein

Source ↕	Mut_ID ↕	Class ↕	HGVS ↕	Disease ↕
Swiss-Prot	VAR_006285	Polymorphism	p.ALA320VAL	N/A
Swiss-Prot	VAR_032482	Polymorphism	p.ARG970CYS	N/A
Swiss-Prot	VAR_041738	Polymorphism	p.ARG143GLN	N/A
dbSNP	rs33917957	Polymorphism	p.ASN375SER	N/A
Swiss-Prot	VAR_006290	Disease	p.ASP1228ASN	Renal cell carcinoma papillary (RCCP)
Swiss-Prot	VAR_006291	Disease	p.ASP1228HIS	Renal cell carcinoma papillary (RCCP)
Swiss-Prot	VAR_064856	Polymorphism	p.CYS385TYR	N/A
Swiss-Prot	VAR_041740	Polymorphism	p.GLU168ASP	N/A
Swiss-Prot	VAR_032487	Disease	p.HIS1094ARG	Renal cell carcinoma papillary (RCCP)
Swiss-Prot	VAR_032489	Disease	p.HIS1106ASP	Renal cell carcinoma papillary (RCCP)
Swiss-Prot	VAR_032486	Disease	p.HIS1094LEU	Renal cell carcinoma papillary (RCCP)
Swiss-Prot	VAR_032488	Disease	p.HIS1094TYR	Renal cell carcinoma papillary (RCCP)
Swiss-Prot	VAR_064855	Polymorphism	p.HIS150TYR	N/A
Swiss-Prot	VAR_032479	Polymorphism	p.ILE316MET	N/A
Swiss-Prot	VAR_032478	Polymorphism	p.LEU238SER	N/A
Swiss-Prot	VAR_006288	Disease	p.LEU1195VAL	Renal cell carcinoma papillary (RCCP)
Swiss-Prot	VAR_032492	Disease	p.LYS1244ARG	Hepatocellular carcinoma (HCC)
Swiss-Prot	VAR_032493	Disease	p.MET1250ILE	Hepatocellular carcinoma (HCC)
Swiss-Prot	VAR_006286	Disease	p.MET1131THR	Renal cell carcinoma papillary (RCCP)
Swiss-Prot	VAR_006294	Disease	p.MET1250THR	Renal cell carcinoma papillary (RCCP)
Swiss-Prot	VAR_032481	Polymorphism	p.PRO773LEU	N/A
Swiss-Prot	VAR_032483	Polymorphism	p.PRO991SER	N/A
Swiss-Prot	VAR_041739	Polymorphism	p.SER156LEU	N/A
Swiss-Prot	VAR_032490	Disease	p.THR1173ILE	Hepatocellular carcinoma (HCC)
Swiss-Prot	VAR_032484	Polymorphism	p.THR992ILE	N/A
Swiss-Prot	VAR_032491	Disease	p.TYR1230ASP	Renal cell carcinoma papillary (RCCP)
Swiss-Prot	VAR_006292	Disease	p.TYR1230CYS	Renal cell carcinoma papillary (RCCP)
Swiss-Prot	VAR_006293	Disease	p.TYR1230HIS	Renal cell carcinoma papillary (RCCP)
Swiss-Prot	VAR_032485	Disease	p.VAL1092ILE	Renal cell carcinoma papillary (RCCP)
Swiss-Prot	VAR_006289	Disease	p.VAL1220ILE	Renal cell carcinoma papillary (RCCP)
Swiss-Prot	VAR_064857	Polymorphism	p.VAL1294ILE	N/A
Swiss-Prot	VAR_006287	Disease	p.VAL1188LEU	Renal cell carcinoma papillary (RCCP)
OMIM	164860.0004	Disease	p.ASP1228ASN	RENAL CELL CARCINOMA, PAPILLARY, 1
OMIM	164860.0007	Disease	p.HIS1094ARG	RENAL CELL CARCINOMA, PAPILLARY, 1
OMIM	164860.0006	Disease	p.LEU1195VAL	RENAL CELL CARCINOMA, PAPILLARY, 1, SOMATIC
OMIM	164860.0010	Disease	p.LYS1244ARG	HEPATOCELLULAR CARCINOMA, CHILDHOOD TYPE, SOMATIC
OMIM	164860.0009	Disease	p.MET1250ILE	HEPATOCELLULAR CARCINOMA, CHILDHOOD TYPE, SOMATIC
OMIM	164860.0001	Disease	p.MET1131THR	RENAL CELL CARCINOMA, PAPILLARY, 1
OMIM	164860.0008	Disease	p.THR1173ILE	HEPATOCELLULAR CARCINOMA, CHILDHOOD TYPE, SOMATIC
OMIM	164860.0005	Disease	p.TYR1230CYS	RENAL CELL CARCINOMA, PAPILLARY, 1
OMIM	164860.0003	Disease	p.VAL1220ILE	RENAL CELL CARCINOMA, PAPILLARY, 1
OMIM	164860.0002	Disease	p.VAL1188LEU	RENAL CELL CARCINOMA, PAPILLARY, 1

Please Cite: Peterson, T.A., Adadey, A., Santana-Cruz ,I., Sun, Y., Winder A, Kann, M.G., (2010) DMDM: Domain Mapping of Disease Mutations. Bioinformatics 26 (19), 2458-2459.

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