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Results for the Protein:
NP_001157961
256773268
101
ADAM8
NCBI
disintegrin and metalloproteinase domain-containing protein 8 isoform 2 precursor [Homo sapiens]
0
2
0
2
0
Tips:
The Domains on the Default View are decided by the Domain's E-Value.
Clicking a check box will display or hide the correlated domain.
To view the Gene page, either click on the link to the left or the blue bar above the Protein's graphic.
Default View:
Pep_M12B_propep - pfam01562
ZnMc - cd00203
Reprolysin - pfam01421
ZnMc_adamalysin_II_l - cd04269
ZnMc_ADAM_like - cd04267
ZnMc_ADAMTS_like - cd04273
ZnMc_salivary_gland_ - cd04272
ZnMc_TACE_like - cd04270
ZnMc_ADAM_fungal - cd04271
Disintegrin - pfam00200
DISIN - smart00050
ACR - smart00608
ADAM_CR - pfam08516
EGF_2 - pfam07974
RefSeq Protein:
NP_001157961
Default View:
Domains
found on the Protein
Domain ↕
CD Accession ↕
E-Value ↕
Start ↕
End ↕
ZnMc_ADAM_like
cd04267
5.6e-39
200
389
ZnMc_ADAMTS_like
cd04273
2.3e-27
200
397
ZnMc_adamalysin_II_l
cd04269
4.7e-100
200
398
ZnMc_salivary_gland_
cd04272
2.3e-08
201
397
ZnMc_TACE_like
cd04270
9.3e-06
203
422
ZnMc_ADAM_fungal
cd04271
3.5e-05
206
397
Pep_M12B_propep
pfam01562
7.9e-53
11
155
Reprolysin
pfam01421
1.3e-112
200
400
Disintegrin
pfam00200
2.8e-39
417
492
DISIN
smart00050
5.7e-40
417
491
ADAM_CR
pfam08516
8e-11
494
585
ACR
smart00608
9e-32
494
605
EGF_2
pfam07974
0.00066
613
640
Table of Mutations found on the Protein
Source ↕
Mut_ID ↕
Class ↕
HGVS ↕
Disease ↕
dbSNP
rs12257830
Polymorphism
p.ARG433CYS
N/A
dbSNP
rs2275725
Polymorphism
p.TRP35ARG
N/A
Please Cite:
Peterson, T.A., Adadey, A., Santana-Cruz ,I., Sun, Y., Winder A, Kann, M.G., (2010) DMDM: Domain Mapping of Disease Mutations. Bioinformatics 26 (19), 2458-2459.
DMDM_info@umbc.edu
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