Results for the protein: Q9UBE8

Results for the Protein: Q9UBE8

262527551

51701

NLK

NCBI, UniProt

NLK_HUMAN RecName: Full=Serine/threonine-protein kinase NLK; AltName: Full=Nemo-like kinase; AltName: Full=Protein LAK1

			0 2 0 0 2

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Swiss-Prot Protein: Q9UBE8

Identical to: NP_057315

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Domains found on the Protein

Domain ↕	CD Accession ↕	E-Value ↕	Start ↕	End ↕
STKc_TAO1	cd06635	1.8e-06	110	411
STKc_JNK2	cd07876	8.4e-54	111	487
STKc_myosinIIIB	cd06639	1.7e-05	113	396
STKc_PAK1	cd06654	5.7e-06	115	449
STKc_PAK	cd06614	5.7e-16	116	439
STKc_PAK_I	cd06647	7.1e-06	116	444
STKc_PAK2	cd06655	6.6e-06	116	450
STKc_PAK3	cd06656	1.3e-06	116	406
STKc_TAO3	cd06633	3.4e-05	117	419
STKc_myosinIIIA	cd06638	2.9e-05	117	427
PTKc_FGFR2	cd05101	0.00026	120	400
STKc_PAK5	cd06658	1.5e-07	122	436
PTKc_FGFR4	cd05099	1.8e-05	123	413
STKc_STK10_LOK	cd06644	3.9e-05	123	416
STKc_PAK6	cd06659	5.6e-09	123	455
STKc_PAK4	cd06657	9.3e-07	124	448
STKc_p38	cd07851	3e-103	124	490
STKc_p38delta_MAPK13	cd07879	7.8e-65	124	490
STKc_p38gamma_MAPK12	cd07880	3.1e-69	124	490
STKc_PAK_II	cd06648	3.8e-11	125	442
STKc_JNK	cd07850	5.5e-73	125	485
STKc_CDK12	cd07864	5.3e-43	125	427
STKc_MAP4K5	cd06646	3.2e-05	126	394
PKc_MKK7	cd06618	4.8e-07	127	419
PTKc_EGFR_like	cd05057	0.00025	128	387
STKc_MAP4K3	cd06645	1.7e-05	128	394
PTKc_EphR_A2	cd05063	0.0002	129	397
STKc_TNIK	cd06637	0.00061	129	427
STKc_p38alpha_MAPK14	cd07877	6.2e-74	129	490
PTKc_Ror	cd05048	7.4e-05	130	360
PTKc_Yes	cd05069	3.5e-05	130	396
PTKc_Fyn_Yrk	cd05070	0.0002	130	396
PTKc_Src	cd05071	8e-05	130	397
PTKc_Hck	cd05073	2.1e-06	130	396
STKc_SLK_like	cd06611	4.7e-06	130	438
STKc_TAO	cd06607	3.4e-06	130	418
STKc_ASK	cd06624	1.4e-08	130	427
STKc_SLK	cd06643	6.3e-05	130	414
STKc_PCTAIRE2	cd07872	1.4e-34	130	447
STKc_PCTAIRE1	cd07873	1.3e-36	130	439
PTKc_Jak_rpt2	cd05038	2.3e-07	131	409
PTKc_Abl	cd05052	4.5e-05	131	405
PTKc_FAK	cd05056	1.1e-06	131	401
PTKc_Lyn	cd05072	7e-05	131	396
PTKc_Tie2	cd05088	7.8e-05	131	403
PTKc_TrkA	cd05092	4.1e-05	131	407
PTKc_Srm_Brk	cd05148	4.2e-07	131	404
STKc_TAO2	cd06634	1.5e-06	131	420
STKc_NAK1_like	cd06917	2.1e-08	131	397
STKc_CdkB_plant	cd07837	5.5e-56	131	428
STKc_TEY_MAPK_plant	cd07858	5e-115	131	490
STKc_PCTAIRE3	cd07871	1.3e-41	131	427
STKc_PFTAIRE2	cd07870	3.1e-39	131	427
STKc_p38beta_MAPK11	cd07878	2.4e-77	131	490
PTKc_InsR_like	cd05032	6e-05	132	394
PTKc_Src_like	cd05034	1.7e-06	132	396
PTKc_ALK_LTK	cd05036	0.00032	132	394
STKc_MST1_2	cd06612	7.6e-13	132	362
STKc_MAP4K3_like	cd06613	1.1e-09	132	397
STKc_JNK3	cd07874	3.9e-50	133	487
STKc_Nek6_Nek7	cd08224	6.3e-09	133	398
PTKc_Trk	cd05049	4.4e-05	134	359
PTKc_FGFR	cd05053	4.2e-06	134	409
PTKc_EphR_A	cd05066	0.00015	134	408
PTKc_Frk_like	cd05068	4.1e-07	134	396
PTKc_Jak1_rpt2	cd05079	0.00082	134	427
PTKc_Tyk2_rpt2	cd05080	0.00017	134	398
PTKc_Chk	cd05083	0.00016	134	396
PTKc_TrkB	cd05093	9.9e-05	134	404
PTKc_TrkC	cd05094	8.7e-05	134	428
PTKc_EGFR	cd05108	0.00059	134	439
PTKc_HER2	cd05109	4.2e-05	134	419
PTK_HER3	cd05111	0.00029	134	411
PTKc_Btk_Bmx	cd05113	1.2e-05	134	397
STKc_MST3_like	cd06609	1.4e-09	134	385
PKc_MKK4	cd06616	8.3e-06	134	408
PKc_MAPKK_plant_like	cd06623	3.5e-15	134	432
STKc_MEKK4	cd06626	6.2e-13	134	427
STKc_MST4	cd06640	0.00031	134	411
STKc_MST3	cd06641	5.1e-05	134	430
STKc_STK25-YSK1	cd06642	3.4e-05	134	414
PKc_MEK2	cd06649	4.8e-05	134	493
PKc_MEK1	cd06650	0.00059	134	451
STKc_PCTAIRE_like	cd07844	9.6e-56	134	427
STKc_CDKL2_3	cd07846	8.6e-19	134	427
STKc_CDK6	cd07862	3.3e-37	134	427
STKc_CDK9	cd07865	3e-23	134	427
STKc_BUR1	cd07866	5.9e-35	134	427
STKc_PFTAIRE1	cd07869	4e-26	134	437
STKc_Nek7	cd08229	2.2e-07	134	398
STKc_MEKK2	cd06652	1.3e-05	135	402
STKc_MEKK3_like_1	cd06653	5.2e-07	135	401
STKc_MEKK3	cd06651	3.2e-07	135	397
STKc_CDK8_like	cd07842	2.6e-23	135	427
STKc_ERK5	cd07855	4.1e-116	135	488
PTK_Ryk	cd05043	3.4e-05	136	356
PTKc_EphR_B	cd05065	0.00076	136	393
STKc_ROCK_NDR_like	cd05573	2.3e-07	136	511
STKc_phototropin_lik	cd05574	1.5e-05	136	394
STKc_PKA	cd05580	6.7e-07	136	401
STKc_PDK1	cd05581	1.8e-11	136	427
STKc_CRIK	cd05601	2.5e-05	136	485
STKc_MAST	cd05609	3.7e-07	136	456
STKc_PRKX_like	cd05612	1.3e-05	136	402
PKc_MAPKK	cd06605	1.1e-11	136	429
STKc_OSR1_SPAK	cd06610	5.7e-11	136	427
PKc_MEK	cd06615	2.2e-08	136	442
PKc_MKK3_6	cd06617	2.5e-07	136	409
PKc_MKK5	cd06619	8.5e-05	136	446
PKc_MAPKK_Pek1_like	cd06621	2.6e-08	136	442
STKc_ERK1_2_like	cd07849	2.9e-101	136	487
STKc_MAPK4_6	cd07854	8e-52	136	489
STKc_CDC2L6	cd07867	2.6e-20	136	427
STKc_CDK8	cd07868	1e-21	136	427
SPS1	COG0515	3e-51	136	524
PTKc_EphR	cd05033	6.4e-05	137	366
PTKc_Csk_like	cd05039	0.00061	137	325
PTKc_Musk	cd05050	1.9e-05	137	395
PTKc_Tie1	cd05089	0.00014	137	419
PKc_STE	cd05122	3.1e-23	137	426
STKc_Yank1	cd05578	5.4e-13	137	427
STKc_MSK_N	cd05583	2.5e-05	137	457
STKc_cPKC	cd05587	5.8e-05	137	475
STKc_GRK4_like	cd05605	1.1e-06	137	430
STKc_DMPK_like	cd05597	0.00041	137	464
STKc_MSK1_N	cd05613	9.2e-05	137	428
STKc_MSK2_N	cd05614	6.5e-06	137	500
STKc_MRCK_alpha	cd05623	0.00091	137	453
STKc_GRK4	cd05631	0.00023	137	430
STKc_GRK5	cd05632	0.0003	137	430
STKc_MRCK_beta	cd05624	0.00066	137	452
STKc_GRK6	cd05630	0.00022	137	430
STKc_MAPKKK	cd06606	4.1e-20	137	427
PKc_MAPKK_Byr1_like	cd06620	1.4e-07	137	433
PKc_MAPKK_PBS2_like	cd06622	5.4e-05	137	478
STKc_MAPK	cd07834	9e-181	137	484
STKc_Pho85	cd07836	3.3e-56	137	427
STKc_CDK5	cd07839	4.2e-42	137	427
STKc_CDKL1_4	cd07847	1.4e-46	137	427
STKc_CDKL5	cd07848	7.8e-24	137	427
STKc_NLK	cd07853		137	508
STKc_TDY_MAPK_plant	cd07859	1.1e-90	137	490
STKc_CDK2_3	cd07860	8.3e-63	137	427
STKc_CDK1_euk	cd07861	2.3e-60	137	427
STKc_CDK4	cd07863	5.7e-50	137	427
STKc_Nek	cd08215	1e-16	137	427
STKc_Nek1	cd08218	8.6e-07	137	395
STKc_Nek3	cd08219	1.3e-09	137	395
STKc_Nek5	cd08225	1.5e-06	137	389
STKc_Nek6	cd08228	1.9e-06	137	398
STKc_Nek8	cd08220	2.4e-06	137	427
STKc_Nek10	cd08528	1.3e-05	137	378
STKc_FA2-like	cd08529	2.9e-11	137	362
PTKc_Tec_like	cd05059	4.4e-06	138	397
PTKc_Itk	cd05112	6e-06	138	393
PTKc_Tec_Rlk	cd05114	1.5e-06	138	394
STKc_CDK1_like	cd07835	8.7e-61	138	427
STKc_MAPK15	cd07852	2.7e-52	138	454
STKc_CDK_like	cd07829	1.4e-77	139	427
STKc_CDK4_6_like	cd07838	2.3e-41	139	427
STKc_CDK9_like	cd07840	4.6e-61	139	427
STKc_CDK7	cd07841	3.3e-57	139	440
PK_STRAD	cd08216	0.00029	139	434
STKc_Nek9	cd08221	8.6e-10	139	427
STKc_p70S6K	cd05584	6.8e-05	141	460
STKc_Cdc7_like	cd06627	3.5e-15	141	427
STKc_Nek11	cd08222	1.6e-06	141	427
PTKc	cd00192	1.4e-09	142	394
PTKc_Ack_like	cd05040	1.3e-06	142	358
PTKc_c-ros	cd05044	0.00081	142	359
PTKc_Fes_like	cd05041	6.1e-06	142	391
PTKc_Met_Ron	cd05058	4e-06	142	402
PTKc_Syk_like	cd05060	0.00068	142	370
PTKc_Jak2_Jak3_rpt2	cd05081	3.5e-05	142	397
PTKc_Fes	cd05084	5e-06	142	394
STKc_CMGC	cd05118	3.6e-103	142	427
PTKc_Syk	cd05116	0.00058	142	410
STKc_PKC	cd05570	7.3e-05	142	485
STKc_PKB	cd05571	8.6e-08	142	489
STKc_SGK	cd05575	0.00024	142	511
STKc_RSK_N	cd05582	0.00019	142	458
STKc_aPKC	cd05588	0.0001	142	499
STKc_nPKC_eta	cd05590	0.00052	142	498
STKc_nPKC_theta_delt	cd05592	6.6e-06	142	500
STKc_PKB_gamma	cd05593	2e-05	142	492
STKc_PKB_beta	cd05595	0.00012	142	475
STKc_PKB_alpha	cd05594	4.8e-06	142	472
STKc_LATS	cd05598	0.00037	142	485
STKc_nPKC_epsilon	cd05591	0.00022	142	496
STKc_nPKC_theta	cd05619	2.4e-06	142	500
STKc_aPKC_zeta	cd05617	0.00053	142	470
STKc_MEKK3_like	cd06625	1.1e-12	142	427
STKc_MEKK1_plant	cd06632	5.6e-13	142	427
STKc_MAK_like	cd07830	5.5e-45	142	427
STKc_CCRK	cd07832	2.9e-66	142	428
STKc_Sty1_Hog1	cd07856	9.4e-92	142	484
STKc_MPK1	cd07857	4.1e-101	142	485
STKc_Nek4	cd08223	1.9e-06	142	427
STKc_Rim15_like	cd05611	9.6e-06	143	428
PKc	cd00180	2.4e-73	144	425
PTKc_Tie	cd05047	0.0007	144	409
PTKc_Fer	cd05085	0.00017	144	398
STKc_AGC	cd05123	2.9e-13	144	427
STKc_cGK_PKG	cd05572	1.5e-08	144	430
STKc_GRK	cd05577	2.5e-06	144	429
STKc_MAST_like	cd05579	5.2e-14	144	429
STKc_YPK1_like	cd05585	7.4e-05	144	494
STKc_Sck1_like	cd05586	2.6e-05	144	510
STKc_PKN	cd05589	0.00022	144	474
STKc_Sid2p_Dbf2p	cd05600	0.00068	144	495
STKc_beta_ARK	cd05606	8.3e-06	144	425
STKc_GRK1	cd05608	3.1e-05	144	429
STKc_GRK3	cd05633	0.00029	144	426
STKc_GRK7	cd05607	3.1e-06	144	429
STKc_myosinIII_like	cd06608	2.2e-09	144	427
STKc_MAPKKK_Byr2_lik	cd06628	2.1e-12	144	427
STKc_MAPKKK_Bck1_lik	cd06629	9.9e-09	144	427
STKc_MEKK1	cd06630	3.2e-07	144	383
STKc_YSK4	cd06631	1.2e-07	144	395
STKc_MOK	cd07831	1.7e-22	144	427
STKc_CDKL	cd07833	1.1e-20	144	427
STKc_CDK10	cd07845	2.2e-43	144	438
STKc_Nek2	cd08217	2.6e-11	144	427
STKc_CNK2-like	cd08530	3.3e-10	145	427
STKc_CDC2L1	cd07843	1.4e-42	146	427
Pkinase	pfam00069	6.7e-80	138	427
Pkinase_Tyr	pfam07714	1.2e-13	138	389
TyrKc	smart00219	2.2e-12	138	427
STYKc	smart00221	2.3e-84	138	427
S_TKc	smart00220	2.4e-93	148	427
KIND	smart00750	9.5e-05	226	399

Table of Mutations found on the Protein

Source ↕	Mut_ID ↕	Class ↕	HGVS ↕	Disease ↕
Swiss-Prot	VAR_042273	Polymorphism	p.ALA343THR	N/A
Swiss-Prot	VAR_019549	Polymorphism	p.VAL177ALA	N/A

Please Cite: Peterson, T.A., Adadey, A., Santana-Cruz ,I., Sun, Y., Winder A, Kann, M.G., (2010) DMDM: Domain Mapping of Disease Mutations. Bioinformatics 26 (19), 2458-2459.

DMDM_info@umbc.edu | 1000 Hilltop Circle, Baltimore, MD 21250 | Department of Biological Sciences | Phone: 410-455-2258