Results for the protein: NP

Results for the Protein: NP_705720

27437019

10645

CAMKK2

NCBI

calcium/calmodulin-dependent protein kinase kinase 2 isoform 4 [Homo sapiens]

			0 4 0 4 0

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RefSeq Protein: NP_705720

Default View:

Domains found on the Protein

Domain ↕	CD Accession ↕	E-Value ↕	Start ↕	End ↕
STKc_ROCK1	cd05622	9.5e-09	125	498
STKc_ROCK	cd05596	6.8e-10	129	478
STKc_TAO1	cd06635	1.4e-06	138	484
STKc_TAO3	cd06633	2.2e-05	142	484
STKc_PAK_I	cd06647	5.6e-08	143	466
STKc_JNK2	cd07876	8.4e-05	144	498
STKc_p38alpha_MAPK14	cd07877	0.00015	144	488
STKc_myosinIIIB	cd06639	2.1e-09	145	449
STKc_PAK2	cd06655	4.3e-08	145	469
STKc_PAK3	cd06656	4.7e-08	145	470
STKc_PAK6	cd06659	5.7e-09	145	468
STKc_myosinIIIA	cd06638	1.7e-10	146	448
STKc_TAO	cd06607	5.9e-07	147	484
STKc_TAO2	cd06634	2.7e-07	147	485
STKc_JNK3	cd07874	0.00014	147	498
PTKc_FGFR1	cd05098	0.001	148	458
STKc_PAK_II	cd06648	3.1e-11	148	447
STKc_PAK1	cd06654	1.3e-08	148	468
STKc_PAK4	cd06657	5e-07	148	467
STKc_PAK5	cd06658	5.3e-07	148	465
STKc_JNK	cd07850	8.8e-06	148	486
STKc_PAK	cd06614	1.7e-17	149	448
STKc_MAP4K4_6	cd06636	0.0001	149	449
STKc_p38	cd07851	3.9e-09	149	488
STKc_p38gamma_MAPK12	cd07880	4.7e-06	149	488
PKc_MKK7	cd06618	1.3e-07	150	449
PTKc_EGFR_like	cd05057	3.3e-06	151	449
STKc_CDK9	cd07865	2.5e-09	152	435
STKc_STK10_LOK	cd06644	1.4e-08	153	464
PTKc_FGFR4	cd05099	0.00079	154	460
STKc_ASK	cd06624	1.3e-10	156	448
STKc_TNIK	cd06637	8.9e-06	156	449
STKc_Sty1_Hog1	cd07856	1.2e-06	156	472
STKc_BUR1	cd07866	5.4e-11	156	435
PTKc_Tie2	cd05088	1.1e-05	157	469
PKc_MAPKK	cd06605	8.2e-11	157	452
STKc_CDK10	cd07845	3.2e-09	157	454
PTKc_ALK_LTK	cd05036	3.8e-07	158	442
PTKc_Tec_like	cd05059	2.3e-06	158	448
STKc_MST4	cd06640	7.8e-09	158	464
STKc_STK25-YSK1	cd06642	1.6e-09	158	467
STKc_MAP4K3	cd06645	2.6e-10	158	447
STKc_MAP4K5	cd06646	1.1e-08	158	447
STKc_MST3	cd06641	1.4e-08	158	464
STKc_MAPK15	cd07852	1.5e-10	158	478
PTKc_Trk	cd05049	4.1e-10	159	446
PTKc_Chk	cd05083	7e-06	159	450
PTKc_Csk	cd05082	1.3e-05	159	447
PTKc_TrkA	cd05092	1.8e-05	159	450
PTKc_TrkB	cd05093	4.6e-06	159	456
PTKc_TrkC	cd05094	0.00032	159	456
PTKc_Ror	cd05048	3.2e-07	159	422
PTKc_EGFR	cd05108	0.00079	159	492
STKc_CDC2L1	cd07843	1.5e-09	159	435
PTKc_InsR_like	cd05032	1.9e-08	160	446
PTKc_Src_like	cd05034	1e-07	160	440
PTKc_Jak_rpt2	cd05038	4.1e-11	160	444
PTKc_Csk_like	cd05039	2.9e-06	160	405
PTKc_Musk	cd05050	3.3e-07	160	446
PTKc_Abl	cd05052	7.3e-08	160	448
PTKc_FGFR	cd05053	7.3e-07	160	452
PTKc_FAK	cd05056	3.4e-09	160	452
PTKc_InsR	cd05061	0.00012	160	457
PTKc_IGF-1R	cd05062	3.1e-05	160	446
PTKc_EphR_B	cd05065	0.00022	160	448
PTKc_Lck_Blk	cd05067	0.00027	160	447
PTKc_Frk_like	cd05068	5.6e-08	160	447
PTKc_Yes	cd05069	6.1e-05	160	447
PTKc_Fyn_Yrk	cd05070	0.00027	160	447
PTKc_Src	cd05071	0.00015	160	449
PTKc_Lyn	cd05072	1.5e-05	160	447
PTKc_Hck	cd05073	7.7e-05	160	447
PTKc_Ror1	cd05090	1.4e-05	160	447
PTKc_Ror2	cd05091	0.00036	160	447
PTKc_DDR2	cd05095	1.3e-05	160	446
PTKc_DDR_like	cd05097	5.1e-05	160	446
PTKc_Itk	cd05112	1.8e-06	160	448
PTKc_Btk_Bmx	cd05113	6.6e-07	160	448
PTKc_Tec_Rlk	cd05114	3.6e-06	160	448
STKc_TEY_MAPK_plant	cd07858	4.9e-08	160	487
STKc_CDK12	cd07864	1.8e-11	160	448
PTK_CCK4	cd05046	6.7e-05	161	446
STKc_GRK6	cd05630	1.9e-07	161	461
STKc_GRK5	cd05632	6.2e-08	161	475
STKc_MAP4K3_like	cd06613	1.9e-16	161	448
PKc_MAPKK_Byr1_like	cd06620	2.6e-08	161	454
STKc_PCTAIRE_like	cd07844	5.9e-08	161	478
STKc_ERK5	cd07855	5.9e-10	161	486
STKc_PFTAIRE1	cd07869	0.0005	161	497
STKc_PFTAIRE2	cd07870	2.6e-05	161	448
STKc_PCTAIRE3	cd07871	3.5e-06	161	447
STKc_PCTAIRE2	cd07872	6.2e-05	161	465
STKc_PCTAIRE1	cd07873	3.9e-05	161	457
STKc_p38beta_MAPK11	cd07878	6.8e-05	161	483
PTKc_Jak1_rpt2	cd05079	4e-05	162	448
PTKc_Tyk2_rpt2	cd05080	1.4e-06	162	449
PTKc_Jak2_Jak3_rpt2	cd05081	8.7e-07	162	448
PTKc_Tie1	cd05089	2.1e-05	162	461
STKc_CDC2L6	cd07867	2.1e-05	162	488
STKc_CDK8	cd07868	3e-05	162	490
STKc_Nek6_Nek7	cd08224	9.9e-12	162	449
STKc_Nek6	cd08228	3.6e-09	162	449
STKc_Nek7	cd08229	2.7e-11	162	449
PTKc_DDR	cd05051	5.4e-05	163	446
STKc_ROCK_NDR_like	cd05573	2.8e-16	163	498
STKc_PKA	cd05580	9.1e-18	163	456
STKc_PDK1	cd05581	1.3e-36	163	443
STKc_DMPK_like	cd05597	5.2e-09	163	496
STKc_LATS	cd05598	5.3e-10	163	493
STKc_Sid2p_Dbf2p	cd05600	7.6e-08	163	496
STKc_CRIK	cd05601	1.3e-13	163	496
STKc_PRKX_like	cd05612	8.1e-19	163	487
STKc_MRCK_alpha	cd05623	5.6e-09	163	497
STKc_MRCK_beta	cd05624	1.8e-08	163	496
STKc_LATS2	cd05626	3.1e-05	163	498
STKc_NDR2	cd05627	1.5e-05	163	493
STKc_NDR1	cd05628	1.4e-07	163	493
STKc_NDR_like_fungal	cd05629	5.1e-06	163	493
STKc_MAST	cd05609	2.8e-22	163	493
STKc_LATS1	cd05625	2.7e-06	163	498
STKc_MST3_like	cd06609	8e-16	163	451
STKc_OSR1_SPAK	cd06610	3.8e-13	163	449
STKc_MST1_2	cd06612	9.6e-17	163	435
PKc_MEK	cd06615	3.8e-07	163	467
PKc_MKK3_6	cd06617	6.1e-08	163	465
PKc_MKK5	cd06619	1.2e-05	163	471
PKc_MAPKK_PBS2_like	cd06622	9.2e-08	163	476
PKc_MAPKK_plant_like	cd06623	1.1e-16	163	449
STKc_MEKK3_like	cd06625	1.3e-13	163	449
STKc_myosinIII_like	cd06608	2.6e-14	163	442
STKc_SLK	cd06643	5.1e-10	163	466
STKc_MEKK2	cd06652	7.3e-07	163	449
STKc_MEKK3_like_1	cd06653	4.7e-08	163	449
STKc_NAK1_like	cd06917	1.2e-11	163	452
STKc_CDKL	cd07833	1.9e-08	163	440
STKc_CdkB_plant	cd07837	1.9e-09	163	449
STKc_CDKL2_3	cd07846	4.5e-09	163	479
STKc_CDKL1_4	cd07847	1.2e-07	163	479
STKc_CDKL5	cd07848	1.2e-06	163	453
STKc_ERK1_2_like	cd07849	7e-08	163	466
STKc_MAPK4_6	cd07854	2e-06	163	482
STKc_CDK6	cd07862	1.1e-05	163	472
SPS1	COG0515	6.4e-42	163	497
PTKc_RET	cd05045	0.00019	164	446
PKc_STE	cd05122	7.5e-30	164	437
STKc_Yank1	cd05578	5.6e-23	164	446
STKc_MSK_N	cd05583	1.1e-10	164	473
STKc_cPKC	cd05587	2.3e-13	164	497
STKc_GRK4_like	cd05605	1.3e-10	164	482
STKc_MSK1_N	cd05613	7.4e-08	164	473
STKc_MSK2_N	cd05614	2.4e-09	164	498
STKc_cPKC_alpha	cd05615	9.8e-09	164	490
STKc_cPKC_beta	cd05616	6.7e-07	164	490
STKc_GRK4	cd05631	1.5e-07	164	470
STKc_MAPKKK	cd06606	1.2e-33	164	440
STKc_MEKK4	cd06626	1.7e-14	164	440
STKc_Cdc7_like	cd06627	2.1e-19	164	443
STKc_MAPKKK_Byr2_lik	cd06628	3.1e-16	164	448
STKc_YSK4	cd06631	9.3e-08	164	448
STKc_MEKK3	cd06651	3.9e-09	164	448
STKc_CCRK	cd07832	1.8e-14	164	454
STKc_Pho85	cd07836	4.3e-08	164	453
STKc_CDK5	cd07839	8.5e-08	164	472
STKc_CDK7	cd07841	1.2e-11	164	441
STKc_MAPK	cd07834	3.3e-12	164	477
STKc_CDK8_like	cd07842	3.1e-10	164	435
STKc_MPK1	cd07857	1.2e-08	164	478
STKc_TDY_MAPK_plant	cd07859	8.2e-07	164	497
STKc_CDK2_3	cd07860	7.6e-13	164	453
STKc_CDK1_euk	cd07861	6e-07	164	453
STKc_CDK4	cd07863	1.3e-07	164	448
STKc_Nek	cd08215	1.2e-24	164	444
STKc_Nek2	cd08217	3.8e-13	164	440
STKc_Nek1	cd08218	6.9e-14	164	448
STKc_Nek3	cd08219	3.8e-12	164	448
STKc_Nek8	cd08220	1.1e-07	164	444
STKc_Nek9	cd08221	7.2e-07	164	448
STKc_Nek4	cd08223	2.7e-13	164	448
STKc_Nek5	cd08225	3e-14	164	448
STKc_Nek11	cd08222	3e-13	164	448
STKc_FA2-like	cd08529	4.9e-14	164	448
STKc_CNK2-like	cd08530	7.1e-11	164	444
STKc_Nek10	cd08528	1.5e-09	164	450
PTKc_Axl_like	cd05035	1.8e-05	165	448
PTKc_Tyro3	cd05074	8.3e-07	165	448
PTKc_Axl	cd05075	0.00019	165	448
STKc_CMGC	cd05118	1.1e-17	165	440
PTKc_Srm_Brk	cd05148	4.3e-07	165	450
STKc_PKN	cd05589	6.1e-11	165	489
PKc_MKK4	cd06616	7.1e-06	165	467
STKc_CDK_like	cd07829	9.1e-19	165	440
STKc_MAK_like	cd07830	7.5e-13	165	443
STKc_MOK	cd07831	1.4e-09	165	453
STKc_CDK1_like	cd07835	3.2e-08	165	474
STKc_CDK4_6_like	cd07838	4.5e-12	165	436
STKc_CDK9_like	cd07840	6.8e-15	165	440
PKc_MEK2	cd06649	0.00078	166	474
STKc_Rim15_like	cd05611	1.3e-10	167	441
STKc_phototropin_lik	cd05574	4.3e-15	168	466
STKc_RSK_N	cd05582	6.7e-07	168	498
STKc_p70S6K	cd05584	1.2e-10	168	498
PTKc	cd00192	1.3e-11	169	445
PTKc_Ack_like	cd05040	6.7e-13	169	445
PTKc_Fes_like	cd05041	9.2e-10	169	442
PTKc_Tie	cd05047	2.6e-05	169	449
PTKc_Met_Ron	cd05058	5.7e-05	169	450
PTKc_Syk_like	cd05060	2.1e-07	169	432
PTKc_Fes	cd05084	4.4e-08	169	449
PTKc_Fer	cd05085	1.9e-07	169	446
PTKc_Syk	cd05116	0.00012	169	445
STKc_PKB	cd05571	4.8e-16	169	495
STKc_SGK	cd05575	3.4e-09	169	498
STKc_aPKC	cd05588	7.5e-09	169	498
STKc_nPKC_eta	cd05590	9.5e-10	169	497
STKc_nPKC_epsilon	cd05591	4.4e-10	169	490
STKc_nPKC_theta_delt	cd05592	2.1e-14	169	488
STKc_SGK2	cd05603	6.5e-11	169	490
STKc_SGK3	cd05604	2e-06	169	490
STKc_nPKC_theta	cd05619	1.5e-10	169	488
STKc_nPKC_delta	cd05620	1.1e-06	169	488
PKc_MAPKK_Pek1_like	cd06621	9e-10	169	448
PTKc_Zap-70	cd05115	4.3e-05	170	449
STKc_SLK_like	cd06611	3.5e-12	170	446
PKc	cd00180	4.2e-84	171	444
STKc_AGC	cd05123	1.9e-36	171	441
STKc_PKC	cd05570	2.9e-16	171	496
STKc_cGK_PKG	cd05572	2.8e-16	171	442
STKc_GRK	cd05577	2.7e-13	171	460
STKc_YPK1_like	cd05585	9.3e-10	171	496
STKc_Sck1_like	cd05586	4.4e-07	171	488
STKc_PKB_gamma	cd05593	2.7e-10	171	480
STKc_PKB_alpha	cd05594	9.2e-11	171	497
STKc_PKB_beta	cd05595	3.6e-09	171	496
STKc_NDR_like	cd05599	1.4e-10	171	464
STKc_SGK1	cd05602	4.2e-08	171	490
STKc_beta_ARK	cd05606	1.5e-08	171	470
STKc_GRK7	cd05607	1.1e-08	171	460
STKc_aPKC_zeta	cd05617	1.5e-08	171	498
STKc_aPKC_iota	cd05618	2.4e-06	171	498
STKc_GRK1	cd05608	1.1e-14	171	474
STKc_GRK3	cd05633	3.4e-07	171	465
STKc_MAST_like	cd05579	4e-20	171	441
STKc_MAPKKK_Bck1_lik	cd06629	1.6e-10	171	433
STKc_MEKK1_plant	cd06632	2.5e-15	171	440
PTK_HER3	cd05111	9.2e-05	188	461
STKc_MEKK1	cd06630	5.3e-10	197	450
STKc_NLK	cd07853	6.9e-08	198	495
PTKc_c-ros	cd05044	9e-05	214	446
Pkinase	pfam00069	2e-67	165	444
Pkinase_Tyr	pfam07714	4.7e-14	165	447
TyrKc	smart00219	3.2e-13	165	447
STYKc	smart00221	2.2e-73	165	446
S_TKc	smart00220	4e-88	175	448
KIND	smart00750	3.5e-05	273	466

Table of Mutations found on the Protein

Source ↕	Mut_ID ↕	Class ↕	HGVS ↕	Disease ↕
dbSNP	rs1132780	Polymorphism	p.ARG363CYS	N/A
dbSNP	rs3815990	Polymorphism	p.ILE365MET	N/A
dbSNP	rs28360477	Polymorphism	p.SER10ASN	N/A
dbSNP	rs3817190	Polymorphism	p.THR85SER	N/A

Please Cite: Peterson, T.A., Adadey, A., Santana-Cruz ,I., Sun, Y., Winder A, Kann, M.G., (2010) DMDM: Domain Mapping of Disease Mutations. Bioinformatics 26 (19), 2458-2459.

DMDM_info@umbc.edu | 1000 Hilltop Circle, Baltimore, MD 21250 | Department of Biological Sciences | Phone: 410-455-2258