Home
News
About DMDM
Database Statistics
Research
Publications
Contact
Results for the Protein:
NP_001163886
282165804
9414
TJP2
NCBI
tight junction protein ZO-2 isoform 4 [Homo sapiens]
0
9
0
9
0
Tips:
The Domains on the Default View are decided by the Domain's E-Value.
Clicking a check box will display or hide the correlated domain.
To view the Gene page, either click on the link to the left or the blue bar above the Protein's graphic.
Default View:
PDZ - smart00228
PDZ_signaling - cd00992
PDZ - cd00136
PDZ_CTP_protease - cd00988
SH3 - smart00326
SH3 - cd00174
SH3_2 - pfam07653
GuKc - smart00072
RefSeq Protein:
NP_001163886
Default View:
Domains
found on the Protein
Domain ↕
CD Accession ↕
E-Value ↕
Start ↕
End ↕
PDZ
cd00136
1.6e-07
46
121
PDZ_CTP_protease
cd00988
0.00059
47
132
PDZ_signaling
cd00992
3.5e-16
309
386
PDZ
cd00136
6.8e-10
321
386
PDZ_signaling
cd00992
1.5e-17
514
593
PDZ
cd00136
4.1e-09
523
593
SH3
cd00174
0.00048
612
670
PDZ
smart00228
5.9e-22
34
124
PDZ
smart00228
2e-14
297
389
PDZ
smart00228
5.3e-17
513
596
SH3
smart00326
0.00019
609
671
SH3_2
pfam07653
1.4e-07
612
670
GuKc
smart00072
2.8e-52
694
883
Table of Mutations found on the Protein
Source ↕
Mut_ID ↕
Class ↕
HGVS ↕
Disease ↕
dbSNP
rs41277901
Polymorphism
p.ARG497LYS
N/A
dbSNP
rs2309428
Polymorphism
p.ASP486GLU
N/A
dbSNP
rs41305539
Polymorphism
p.GLN132LYS
N/A
dbSNP
rs28556975
Polymorphism
p.LEU941PRO
N/A
dbSNP
rs34774441
Polymorphism
p.MET672ILE
N/A
dbSNP
rs116545275
Polymorphism
p.SER717GLY
N/A
dbSNP
rs41277907
Polymorphism
p.SER977PHE
N/A
dbSNP
rs35797487
Polymorphism
p.SER715PRO
N/A
dbSNP
rs77321498
Polymorphism
p.THR368MET
N/A
Please Cite:
Peterson, T.A., Adadey, A., Santana-Cruz ,I., Sun, Y., Winder A, Kann, M.G., (2010) DMDM: Domain Mapping of Disease Mutations. Bioinformatics 26 (19), 2458-2459.
DMDM_info@umbc.edu
| 1000 Hilltop Circle, Baltimore, MD 21250 | Department of Biological Sciences | Phone: 410-455-2258