Results for the protein: NP

Results for the Protein: NP_001180251

300937401

9641

IKBKE

NCBI

inhibitor of nuclear factor kappa-B kinase subunit epsilon isoform 2 [Homo sapiens]

			0 2 0 2 0

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RefSeq Protein: NP_001180251

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Domains found on the Protein

Domain ↕	CD Accession ↕	E-Value ↕	Start ↕	End ↕
PTKc_EGFR_like	cd05057	0.0001	1	313
PTKc_Csk	cd05082	0.00042	1	280
STKc_myosinIIIA	cd06638	2.5e-05	1	290
STKc_myosinIIIB	cd06639	7.4e-06	1	291
STKc_STK10_LOK	cd06644	1.7e-07	1	306
STKc_MAP4K5	cd06646	3.9e-06	1	289
STKc_PAK2	cd06655	9.2e-05	1	292
STKc_PAK3	cd06656	2.4e-05	1	293
STKc_PAK6	cd06659	6.2e-06	1	292
STKc_ERK5	cd07855	0.00077	1	312
STKc_Sty1_Hog1	cd07856	0.0002	1	313
STKc_TEY_MAPK_plant	cd07858	4.7e-06	1	343
STKc_BUR1	cd07866	7.8e-05	1	250
STKc_PFTAIRE2	cd07870	6.8e-05	1	315
STKc_PCTAIRE3	cd07871	5.6e-07	1	304
STKc_PCTAIRE2	cd07872	1.3e-05	1	317
STKc_PCTAIRE1	cd07873	1.5e-05	1	311
STKc_p38gamma_MAPK12	cd07880	3e-05	1	337
PTKc_ALK_LTK	cd05036	1.8e-08	2	290
PTKc_Musk	cd05050	3.5e-05	2	287
PTKc_FAK	cd05056	0.00012	2	277
STKc_TAO	cd06607	2.2e-05	2	286
STKc_PAK	cd06614	5.2e-10	2	281
STKc_TAO1	cd06635	0.00087	2	323
STKc_MAP4K4_6	cd06636	6.5e-05	2	278
STKc_TNIK	cd06637	3.1e-06	2	290
STKc_SLK	cd06643	3.4e-07	2	292
STKc_PAK_II	cd06648	8.7e-06	2	281
STKc_p38	cd07851	7.9e-05	2	337
STKc_CDK12	cd07864	4.6e-08	2	306
PTKc_Jak_rpt2	cd05038	7.8e-09	3	310
PTKc_InsR	cd05061	0.00029	3	286
PTKc_IGF-1R	cd05062	3.6e-05	3	286
PTKc_EphR_A2	cd05063	0.00085	3	285
PTKc_Fyn_Yrk	cd05070	0.00029	3	288
PTKc_Hck	cd05073	4.5e-05	3	288
PKc_MKK7	cd06618	2.9e-07	3	312
STKc_TAO2	cd06634	4.2e-05	3	288
STKc_MAP4K3	cd06645	3.6e-06	3	289
STKc_PAK_I	cd06647	7.1e-05	3	325
STKc_PAK1	cd06654	1.3e-05	3	291
STKc_CDK9	cd07865	2.8e-07	3	299
PTKc_EphR_B	cd05065	0.0004	4	285
PTKc_EphR_A	cd05066	0.0005	4	285
PTKc_Jak1_rpt2	cd05079	3e-05	4	306
STKc_MST4	cd06640	0.0001	4	310
STKc_MST3	cd06641	0.00033	4	310
STKc_STK25-YSK1	cd06642	9e-06	4	310
STKc_PCTAIRE_like	cd07844	1.7e-06	4	325
STKc_Nek6_Nek7	cd08224	2.1e-05	4	293
STKc_Nek7	cd08229	0.00012	4	293
PTKc_EphR	cd05033	0.00011	5	285
PTKc_Tie2	cd05088	0.00014	5	297
STKc_PKA	cd05580	1.4e-06	5	298
STKc_myosinIII_like	cd06608	7.5e-10	5	222
STKc_MAP4K3_like	cd06613	3e-11	5	289
STKc_ASK	cd06624	2.3e-08	5	278
STKc_MST3_like	cd06609	4.1e-10	6	241
STKc_SLK_like	cd06611	6.2e-07	6	258
STKc_Cdc7_like	cd06627	2.3e-14	6	241
STKc_MEKK3	cd06651	6.2e-08	6	284
PKc_MAPKK_plant_like	cd06623	1.9e-12	6	286
STKc_MAPK	cd07834	2.7e-06	6	323
STKc_Nek	cd08215	3.1e-14	6	290
STKc_Nek4	cd08223	6.5e-05	6	290
PTKc_Tyk2_rpt2	cd05080	1.8e-07	7	286
PTKc_TrkA	cd05092	0.0001	7	279
STKc_MAST	cd05609	4.5e-06	7	336
STKc_MAPKKK_Bck1_lik	cd06629	2e-06	7	262
STKc_NAK1_like	cd06917	3.3e-08	7	254
STKc_MAK_like	cd07830	2.2e-09	7	257
STKc_CDK6	cd07862	0.00026	7	310
SPS1	COG0515	5.1e-38	7	546
PKc_STE	cd05122	1.7e-14	8	277
STKc_GRK4_like	cd05605	3.8e-05	8	311
STKc_MAPKKK	cd06606	3.2e-18	8	258
STKc_MEKK4	cd06626	1.3e-12	8	260
STKc_MAPKKK_Byr2_lik	cd06628	1.1e-07	8	278
STKc_MEKK1	cd06630	1.8e-07	8	262
STKc_YSK4	cd06631	3.9e-09	8	262
STKc_MEKK1_plant	cd06632	9.5e-11	8	287
STKc_Pho85	cd07836	1.3e-07	8	304
STKc_CDK7	cd07841	3.1e-08	8	286
STKc_CDK8_like	cd07842	0.00023	8	299
STKc_NLK	cd07853	8.5e-05	8	370
STKc_MPK1	cd07857	9.5e-06	8	324
STKc_TDY_MAPK_plant	cd07859	5.6e-06	8	343
STKc_CDK2_3	cd07860	0.00015	8	299
STKc_CDK4	cd07863	7.5e-06	8	325
STKc_Nek5	cd08225	1.6e-06	8	281
STKc_Nek10	cd08528	1.3e-05	8	294
PTKc_InsR_like	cd05032	1.9e-05	9	283
PTKc_Src_like	cd05034	5.4e-08	9	261
PTKc_Csk_like	cd05039	0.0003	9	207
PTKc_Tec_like	cd05059	4.4e-06	9	266
PTKc_Frk_like	cd05068	2.4e-06	9	288
PTKc_Src	cd05071	0.00021	9	262
PTKc_Lyn	cd05072	5.9e-05	9	288
PTKc_Yes	cd05069	0.00023	9	280
PTKc_Tie1	cd05089	0.00044	9	296
PTKc_Btk_Bmx	cd05113	2.5e-05	9	286
PTKc_Tec_Rlk	cd05114	9.9e-05	9	256
STKc_CMGC	cd05118	2.2e-11	9	299
PTKc_Srm_Brk	cd05148	4e-08	9	260
STKc_cPKC	cd05587	0.00023	9	328
STKc_PKN	cd05589	2.3e-06	9	330
STKc_DMPK_like	cd05597	3.3e-06	9	360
STKc_PRKX_like	cd05612	6.6e-07	9	294
STKc_MSK1_N	cd05613	5.1e-05	9	316
STKc_MSK2_N	cd05614	2.7e-06	9	347
STKc_cPKC_alpha	cd05615	0.00035	9	325
STKc_MRCK_alpha	cd05623	0.00049	9	333
PKc_MKK4	cd06616	3.7e-07	9	310
STKc_MEKK3_like	cd06625	1.1e-09	9	290
PKc_MEK2	cd06649	2.7e-05	9	367
PKc_MEK1	cd06650	1e-05	9	345
STKc_MEKK2	cd06652	2.6e-05	9	283
STKc_MEKK3_like_1	cd06653	5.5e-06	9	275
STKc_CDK_like	cd07829	5.4e-10	9	237
STKc_MOK	cd07831	3.3e-06	9	224
STKc_CDK4_6_like	cd07838	1.7e-07	9	222
STKc_CDK9_like	cd07840	2.4e-08	9	262
STKc_CDKL2_3	cd07846	2.1e-08	9	290
STKc_CDK1_like	cd07835	5.6e-05	9	299
STKc_CDKL1_4	cd07847	4.3e-09	9	325
STKc_ERK1_2_like	cd07849	0.00025	9	359
STKc_CDK1_euk	cd07861	0.00043	9	326
STKc_CDKL5	cd07848	1.1e-05	9	304
STKc_Nek1	cd08218	3.1e-05	9	290
STKc_Nek3	cd08219	4.6e-08	9	290
STKc_Nek11	cd08222	0.00038	9	257
STKc_FA2-like	cd08529	1.4e-07	9	233
PTKc_Trk	cd05049	3.6e-07	10	254
PTKc_TrkB	cd05093	0.00014	10	296
PTKc_Itk	cd05112	5e-05	10	282
STKc_ROCK_NDR_like	cd05573	6.5e-05	10	301
PKc_MAPKK_Byr1_like	cd06620	1.2e-06	10	300
STKc_phototropin_lik	cd05574	9.3e-08	12	274
STKc_PDK1	cd05581	2.4e-11	12	299
STKc_p70S6K	cd05584	2.6e-06	12	329
STKc_CRIK	cd05601	5.6e-07	12	317
STKc_MRCK_beta	cd05624	0.00037	12	331
PKc_MAPKK	cd06605	2.5e-11	12	331
STKc_OSR1_SPAK	cd06610	2.1e-10	12	262
STKc_MST1_2	cd06612	6.3e-14	12	240
PKc_MEK	cd06615	3e-08	12	332
PKc_MKK3_6	cd06617	3e-06	12	286
PKc_MAPKK_Pek1_like	cd06621	7e-09	12	293
PTKc	cd00192	1.1e-08	13	274
PTKc_Ack_like	cd05040	7e-09	13	275
PTKc_Fes_like	cd05041	6e-09	13	252
PTKc_Tie	cd05047	0.00061	13	278
PTKc_Syk_like	cd05060	2.2e-05	13	286
PTKc_Jak2_Jak3_rpt2	cd05081	3e-07	13	289
PTKc_Fes	cd05084	6.6e-05	13	278
PTKc_Fer	cd05085	1.3e-05	13	279
PTKc_Syk	cd05116	3.8e-05	13	278
STKc_PKC	cd05570	3.7e-07	13	298
STKc_PKB	cd05571	6.5e-07	13	357
STKc_SGK	cd05575	5.5e-05	13	360
STKc_RSK_N	cd05582	1.8e-06	13	360
STKc_aPKC	cd05588	3.5e-05	13	361
STKc_nPKC_eta	cd05590	5.7e-05	13	328
STKc_nPKC_epsilon	cd05591	5.2e-05	13	329
STKc_nPKC_theta_delt	cd05592	0.00053	13	347
STKc_PKB_gamma	cd05593	1.7e-05	13	322
STKc_PKB_alpha	cd05594	1.7e-05	13	331
STKc_PKB_beta	cd05595	8.9e-06	13	334
STKc_SGK1	cd05602	0.00025	13	387
STKc_aPKC_zeta	cd05617	6.8e-05	13	327
STKc_aPKC_iota	cd05618	0.0006	13	361
STKc_nPKC_theta	cd05619	1.4e-05	13	329
STKc_SGK2	cd05603	3.7e-06	13	386
PKc_MAPKK_PBS2_like	cd06622	1.9e-05	13	343
STKc_CdkB_plant	cd07837	3.2e-07	13	300
STKc_CDK5	cd07839	1.1e-06	13	299
STKc_CDK10	cd07845	3.2e-06	13	264
STKc_MAPK4_6	cd07854	9.2e-05	13	374
STKc_Nek2	cd08217	5.3e-10	13	290
STKc_CNK2-like	cd08530	2.8e-07	13	290
STKc_MSK_N	cd05583	3.6e-07	14	316
STKc_CDKL	cd07833	1.1e-08	14	299
STKc_Nek8	cd08220	5.1e-06	14	304
STKc_Nek9	cd08221	1.8e-05	14	239
PKc	cd00180	1e-59	15	302
PTKc_Ror	cd05048	2.1e-06	15	276
PTKc_Zap-70	cd05115	1.7e-05	15	293
STKc_AGC	cd05123	3.5e-13	15	314
STKc_cGK_PKG	cd05572	1.2e-08	15	261
STKc_GRK	cd05577	7.8e-05	15	280
STKc_MAST_like	cd05579	4.3e-09	15	245
STKc_YPK1_like	cd05585	4e-05	15	329
STKc_Sck1_like	cd05586	2e-05	15	374
STKc_GRK7	cd05607	0.00062	15	280
STKc_GRK1	cd05608	3.8e-07	15	301
STKc_CCRK	cd07832	4e-10	15	300
STKc_MAPK15	cd07852	0.00071	15	325
STKc_Yank1	cd05578	4.8e-09	16	266
STKc_Rim15_like	cd05611	0.00037	17	329
STKc_CDC2L1	cd07843	3.1e-06	22	246
Pkinase	pfam00069	5.4e-36	9	278
Pkinase_Tyr	pfam07714	1.5e-10	9	277
TyrKc	smart00219	6e-12	9	269
STYKc	smart00221	1.5e-42	9	296
S_TKc	smart00220	1.1e-40	19	306

Table of Mutations found on the Protein

Source ↕	Mut_ID ↕	Class ↕	HGVS ↕	Disease ↕
dbSNP	rs17021877	Polymorphism	p.ALA371THR	N/A
dbSNP	rs12059562	Polymorphism	p.ALA602VAL	N/A

Please Cite: Peterson, T.A., Adadey, A., Santana-Cruz ,I., Sun, Y., Winder A, Kann, M.G., (2010) DMDM: Domain Mapping of Disease Mutations. Bioinformatics 26 (19), 2458-2459.

DMDM_info@umbc.edu | 1000 Hilltop Circle, Baltimore, MD 21250 | Department of Biological Sciences | Phone: 410-455-2258