Results for the protein: Q07869

Results for the Protein: Q07869

3041727

5465

PPARA

NCBI, UniProt

PPARA_HUMAN RecName: Full=Peroxisome proliferator-activated receptor alpha; Short=PPAR-alpha; AltName: Full=Nuclear receptor subfamily 1 group C member 1

Known Diseases associated with this Protein:
HYPERAPOBETALIPOPROTEINEMIA, SUSCEPTIBILITY TO

1

7

1

2

5

Tips:

The Domains on the Default View are decided by the Domain's E-Value.

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Swiss-Prot Protein: Q07869

Identical to: NP_005027, NP_001001928

Default View:

Domains found on the Protein

Domain ↕	CD Accession ↕	E-Value ↕	Start ↕	End ↕
NR_DBD_DHR4_like	cd07168	5.5e-32	91	180
NR_DBD_VDR	cd06955	6.8e-15	94	205
NR_DBD_PNR	cd06970	4.4e-25	94	184
NR_DBD_TLX	cd07163	2.9e-23	94	182
NR_DBD_GCNF_like	cd07169	3.5e-29	94	182
NR_DBD_ROR	cd06968	6.9e-31	95	188
NR_DBD_RAR	cd06964	1e-29	96	179
NR_DBD_ERR	cd07170	5.8e-20	96	192
NR_DBD_TR2_like	cd06967	1.1e-29	97	182
NR_DBD_REV_ERB	cd07166	2.7e-44	97	183
NR_DBD_ER	cd07171	5.6e-21	97	177
NR_DBD_AR	cd07173	3e-09	97	178
NR_DBD_GR_PR	cd07172	5.4e-09	98	174
NR_DBD_FXR	cd06962	1.9e-18	99	181
NR_DBD_NGFI-B	cd06969	3.7e-30	100	173
NR_DBD_EcR_like	cd06959	5.4e-23	101	172
NR_DBD_TR	cd06961	2.1e-32	101	185
NR_DBD_Ppar	cd06965	1.3e-55	101	184
2DBD_NR_DBD1	cd07157	3e-12	101	184
NR_DBD_like	cd06916	5.5e-42	102	172
NR_DBD_RXR	cd06956	7.2e-30	102	175
NR_DBD_PNR_like_2	cd06957	1.2e-22	102	181
NR_DBD_COUP_TF	cd06958	2.6e-24	102	173
NR_DBD_HNF4A	cd06960	1.3e-31	102	176
NR_DBD_GR_like	cd06963	4.1e-13	102	173
NR_DBD_CAR	cd06966	1.7e-12	102	196
NR_DBD_PNR_like	cd07154	1.6e-25	102	172
NR_DBD_ER_like	cd07155	7.7e-24	102	175
NR_DBD_VDR_like	cd07156	6.3e-26	102	172
NR_DBD_Ppar_like	cd07158	1.4e-44	102	172
NR_DBD_EcR	cd07161	4.8e-21	102	185
NR_DBD_PNR_like_1	cd07164	6.8e-27	102	178
NR_DBD_DmE78_like	cd07165	3.9e-40	102	181
NR_DBD_Lrh-1_like	cd07167	8.1e-28	102	190
2DBD_NR_DBD2	cd07179	2.1e-28	102	174
NR_DBD_PXR	cd07162	8.4e-22	102	186
NR_LBD_VDR	cd06933	9.8e-07	178	468
NR_LBD_PXR_like	cd06934	9.9e-07	200	463
NR_LBD_PPAR	cd06932	5.9e-154	201	467
NR_LBD_ROR_like	cd06939	5.6e-12	201	464
NR_LBD_TR	cd06935	2.4e-06	219	463
NR_LBD_Nurr1_like	cd06945	6.5e-05	223	468
NR_LBD_DHR38_like	cd07072	6.8e-05	225	468
NR_LBD_NGFI-B	cd07348	0.00081	232	468
NR_LBD_EcR	cd06938	2.4e-06	240	467
NR_LBD_RXR_like	cd06943	8.3e-08	243	445
NR_LBD_HNF4_like	cd06931	6.3e-06	243	463
NR_LBD_Fxr	cd06936	9.5e-08	244	462
NR_LBD_RAR	cd06937	7.6e-13	244	466
NR_LBD_LXR	cd06954	2.2e-10	244	467
NR_LBD_REV_ERB	cd06940	7.7e-23	258	449
NR_LBD_F1	cd06929	1.8e-55	270	444
NR_LBD_DmE78_like	cd06941	4.3e-10	270	465
NR_LBD_Sex_1_like	cd06942	3.6e-08	273	461
NR_LBD	cd06157	9.9e-35	274	436
NR_LBD_TR2_like	cd06952	0.00025	279	450
NR_LBD_F2	cd06930	0.00015	281	436
zf-C4	pfam00105	6.6e-43	100	168
Hormone_recep	pfam00104	4.6e-31	304	463
ZnF_C4	smart00399	2.3e-35	101	169
HOLI	smart00430	1.7e-24	280	436

Table of Mutations found on the Protein

Source ↕	Mut_ID ↕	Class ↕	HGVS ↕	Disease ↕
Swiss-Prot	VAR_016113	Polymorphism	p.ALA268VAL	N/A
Swiss-Prot	VAR_016110	Polymorphism	p.ARG127GLN	N/A
Swiss-Prot	VAR_016115	Polymorphism	p.ARG409THR	N/A
Swiss-Prot	VAR_016114	Polymorphism	p.ASP304ASN	N/A
Swiss-Prot	VAR_050578	Polymorphism	p.GLY395ARG	N/A
dbSNP	rs1800206	Polymorphism	p.LEU162VAL	N/A
dbSNP	rs1800234	Polymorphism	p.VAL227ALA	N/A
OMIM	170998.0001	Disease	p.LEU162VAL	HYPERAPOBETALIPOPROTEINEMIA, SUSCEPTIBILITY TO

Please Cite: Peterson, T.A., Adadey, A., Santana-Cruz ,I., Sun, Y., Winder A, Kann, M.G., (2010) DMDM: Domain Mapping of Disease Mutations. Bioinformatics 26 (19), 2458-2459.

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