Results for the protein: P51841

Results for the Protein: P51841

311033391

2986

GUCY2F

NCBI, UniProt

GUC2F_HUMAN RecName: Full=Retinal guanylyl cyclase 2; Short=RETGC-2; AltName: Full=Guanylate cyclase 2F, retinal; AltName: Full=Guanylate cyclase F; Short=GC-F; AltName: Full=Rod outer segment membrane guanylate cyclase 2; Short=ROS-GC2; Flags: Precursor

			0 18 0 6 12

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Swiss-Prot Protein: P51841

Identical to: NP_001513

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Domains found on the Protein

Domain ↕	CD Accession ↕	E-Value ↕	Start ↕	End ↕
PBP1_Speract_GC_like	cd06370	1.6e-09	53	430
Periplasmic_Binding_	cd01391	4.9e-38	54	408
PBP1_ABC_transporter	cd04509	7.4e-60	54	409
PBP1_glutamate_recep	cd06269	2.1e-30	54	433
PBP1_NPR_GC_like	cd06352	3.6e-144	54	434
PBP1_GABAb_receptor	cd06366	2.3e-08	54	426
PBP1_GC_G_like	cd06372	1.1e-10	54	432
PBP1_NPR_like	cd06373	1.6e-09	54	432
PBP1_NPR_B	cd06384	0.00028	54	417
PBP1_sensory_GC_DEF_	cd06371	9.8e-283	54	435
PBP1_mGluR	cd06362	0.00093	66	430
PTKc_PDGFR_alpha	cd05105	0.00021	422	815
PTKc_Kit	cd05104	0.00045	422	813
PTKc_VEGFR2	cd05103	0.00015	489	816
SPS1	COG0515	1.3e-10	502	976
PTKc_FAK	cd05056	7.4e-08	506	817
PTKc_DDR	cd05051	8.2e-07	522	811
PTK_CCK4	cd05046	3.8e-06	526	811
PTKc_EphR_A10	cd05064	1.2e-08	526	813
PTKc_DDR2	cd05095	2.5e-05	526	811
STKc_PAK	cd06614	1.6e-07	527	824
PTKc_EphR_B	cd05065	3.4e-09	528	813
STKc_MAP4K3_like	cd06613	4.9e-05	528	809
STKc_Nek6_Nek7	cd08224	0.00043	529	814
STKc_Nek7	cd08229	0.00039	530	814
PTKc_EphR_A	cd05066	9e-07	531	813
PTKc_FGFR4	cd05099	1.2e-06	532	834
PTKc_EGFR	cd05108	6.9e-06	532	859
PTKc_HER2	cd05109	7.7e-05	532	823
PTKc_HER4	cd05110	9.1e-05	532	843
STKc_PAK_II	cd06648	2e-05	533	825
STKc_PAK6	cd06659	0.001	534	834
PTKc_FGFR1	cd05098	8.6e-05	535	815
PTK_HER3	cd05111	2.8e-06	536	823
PTKc_InsR	cd05061	2.9e-05	537	822
PTKc_FGFR2	cd05101	1e-05	537	815
PTKc_Axl_like	cd05035	3.1e-05	538	813
PTKc_Tyro3	cd05074	0.00011	538	813
PTK_Jak1_rpt1	cd05077	3.7e-06	539	810
STKc_MAP4K3	cd06645	0.00084	540	809
PTKc_FGFR3	cd05100	0.00014	541	853
STKc_CDKL1_4	cd07847	0.00065	541	844
PTKc_DDR_like	cd05097	0.00011	542	811
PTKc_Jak1_rpt2	cd05079	5.2e-05	543	813
PTKc_ALK_LTK	cd05036	7.5e-08	544	811
PTKc_Abl	cd05052	6.6e-16	545	813
PTKc_EGFR_like	cd05057	9.8e-07	545	823
PTKc_IGF-1R	cd05062	1.7e-05	545	811
PTKc_Fyn_Yrk	cd05070	5.4e-07	545	812
PTKc_Ror	cd05048	4.3e-09	545	812
PTKc_Ror1	cd05090	2.5e-06	545	812
PTKc_Ror2	cd05091	5.9e-06	545	812
STKc_MEKK3	cd06651	0.00073	545	812
PTK_Jak_rpt1	cd05037	0.00041	546	810
PTKc_Chk	cd05083	1.4e-09	546	812
PTKc_Itk	cd05112	7.7e-10	546	810
STKc_MAPKKK_Byr2_lik	cd06628	3e-06	547	811
STKc_Pho85	cd07836	0.00078	547	844
PK_STRAD	cd08216	5e-05	548	827
PTKc_Met_Ron	cd05058	1.7e-14	549	815
PTKc_Syk	cd05116	8.6e-06	551	814
STKc_CDK12	cd07864	0.00069	551	829
PTKc_EphR_A2	cd05063	1.1e-07	552	813
STKc_ASK	cd06624	0.00019	552	811
PKc	cd00180	1.5e-38	553	809
PTKc_EphR	cd05033	1e-10	554	813
PTKc_Hck	cd05073	1.4e-09	554	812
PTKc_Src	cd05071	2e-07	554	814
PTKc_Yes	cd05069	1.3e-08	554	812
PTK_Ryk	cd05043	2.8e-06	556	816
PTKc_Tie2	cd05088	4.4e-07	556	835
STKc_CDKL2_3	cd07846	0.00013	556	809
PTKc_Musk	cd05050	1.3e-06	557	811
PTKc_PDGFR	cd05055	0.00026	557	813
PTKc_Trk	cd05049	1.9e-07	557	811
STKc_YSK4	cd06631	0.00053	557	810
STKc_CDK5	cd07839	0.00051	557	844
PTKc_InsR_like	cd05032	6.2e-08	558	811
PTKc_Jak_rpt2	cd05038	2.6e-10	558	813
PTKc_Tie1	cd05089	1.2e-06	558	837
STKc_CMGC	cd05118	1.1e-06	558	802
STKc_CDK9_like	cd07840	9.6e-05	558	802
PTK_Jak2_Jak3_rpt1	cd05078	0.00069	559	810
STKc_Cdc7_like	cd06627	1.2e-06	560	806
PTKc_Ack_like	cd05040	2.3e-11	561	811
PTKc_Csk_like	cd05039	6.1e-13	563	812
PTKc_Lck_Blk	cd05067	3e-07	563	812
PTKc_Frk_like	cd05068	2.9e-16	563	812
PTKc_Lyn	cd05072	2.5e-09	563	812
PTKc_Csk	cd05082	1.5e-11	563	812
STKc_MEKK1_plant	cd06632	7.3e-06	563	807
PTKc_Tie	cd05047	4.7e-06	564	814
PTKc_TrkA	cd05092	0.00015	564	811
PTKc_TrkB	cd05093	0.00077	564	821
PTKc	cd00192	1.5e-13	565	810
PTKc_Src_like	cd05034	7.4e-13	565	812
PTKc_c-ros	cd05044	2e-06	565	811
PTKc_Tec_like	cd05059	3.6e-12	565	810
PTKc_Jak2_Jak3_rpt2	cd05081	5.9e-09	565	813
PTKc_Fer	cd05085	1.3e-07	565	811
PTKc_Btk_Bmx	cd05113	2.6e-12	565	810
PTKc_Tec_Rlk	cd05114	1.3e-10	565	810
STKc_NLK	cd07853	0.00085	565	870
PTKc_FGFR	cd05053	9.6e-07	566	814
PTKc_Aatyk2	cd05086	9.4e-05	566	811
PTKc_Aatyk1_Aatyk3	cd05087	0.00053	566	811
PTKc_RET	cd05045	0.00029	569	815
PKc_STE	cd05122	2.8e-07	569	812
STKc_MEKK3_like	cd06625	2.1e-06	569	811
STKc_MEKK4	cd06626	4e-05	569	805
STKc_Nek	cd08215	2.1e-06	569	811
STKc_MAPKKK_Bck1_lik	cd06629	2.2e-05	570	810
STKc_MAST_like	cd05579	0.00064	571	814
STKc_MEKK1	cd06630	0.00083	571	810
PTKc_Aatyk	cd05042	1.2e-06	572	812
PTKc_Tyk2_rpt2	cd05080	3.8e-09	572	814
PTKc_Srm_Brk	cd05148	5.7e-10	572	812
PTKc_Fes_like	cd05041	5.2e-16	574	811
PTKc_Syk_like	cd05060	3.4e-07	574	814
PTKc_Fes	cd05084	7.2e-08	574	811
STKc_MST1_2	cd06612	0.00031	574	805
PTKc_Zap-70	cd05115	9e-07	575	814
STKc_MAPKKK	cd06606	1.4e-10	575	805
STKc_MAPK	cd07834	3.2e-05	575	845
STKc_CDK7	cd07841	1.4e-06	575	826
STKc_CDK_like	cd07829	4.8e-06	576	809
STKc_PDK1	cd05581	0.00025	580	806
CHD	cd07302	5.3e-69	882	1060
Nucleotidyl_cyc_III	cd07556	1.4e-43	882	1023
ANF_receptor	pfam01094	2.5e-79	71	412
Pkinase	pfam00069	2.9e-12	532	809
CyaA	COG2114	1.9e-33	832	1075
Guanylate_cyc	pfam00211	6e-90	875	1061
STYKc	smart00221	3.4e-06	532	811
S_TKc	smart00220	4.5e-14	549	812
Pkinase_Tyr	pfam07714	1.1e-16	558	809
TyrKc	smart00219	3.3e-14	558	809
CYCc	smart00044	2.8e-107	848	1043

Table of Mutations found on the Protein

Source ↕	Mut_ID ↕	Class ↕	HGVS ↕	Disease ↕
Swiss-Prot	VAR_042241	Polymorphism	p.ALA1010VAL	N/A
dbSNP	rs502209	Polymorphism	p.ARG296GLN	N/A
Swiss-Prot	VAR_042236	Polymorphism	p.ARG305GLN	N/A
Swiss-Prot	VAR_030635	Polymorphism	p.ARG628GLN	N/A
Swiss-Prot	VAR_036419	Polymorphism	p.ARG10PRO	N/A
dbSNP	rs33973457	Polymorphism	p.ARG230TRP	N/A
dbSNP	rs2272925	Polymorphism	p.GLN380HIS	N/A
Swiss-Prot	VAR_042243	Polymorphism	p.GLU1055ASP	N/A
Swiss-Prot	VAR_042240	Polymorphism	p.GLU794LYS	N/A
Swiss-Prot	VAR_042237	Polymorphism	p.GLY434ARG	N/A
Swiss-Prot	VAR_042238	Polymorphism	p.GLY568ASP	N/A
Swiss-Prot	VAR_069424	Polymorphism	p.GLY872ASP	N/A
dbSNP	rs33971675	Polymorphism	p.ILE160ASN	N/A
dbSNP	rs12008095	Polymorphism	p.LEU284PRO	N/A
Swiss-Prot	VAR_042242	Polymorphism	p.LYS1052ARG	N/A
Swiss-Prot	VAR_042233	Polymorphism	p.SER40CYS	N/A
dbSNP	rs16985750	Polymorphism	p.TYR308CYS	N/A
Swiss-Prot	VAR_042239	Polymorphism	p.VAL677LEU	N/A

Please Cite: Peterson, T.A., Adadey, A., Santana-Cruz ,I., Sun, Y., Winder A, Kann, M.G., (2010) DMDM: Domain Mapping of Disease Mutations. Bioinformatics 26 (19), 2458-2459.

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