Results for the protein: Q9UP79

Results for the Protein: Q9UP79

313104077

11095

ADAMTS8

NCBI, UniProt

ATS8_HUMAN RecName: Full=A disintegrin and metalloproteinase with thrombospondin motifs 8; Short=ADAM-TS 8; Short=ADAM-TS8; Short=ADAMTS-8; AltName: Full=METH-2; AltName: Full=METH-8; Flags: Precursor

			0 5 0 5 0

Tips:

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Default View: Pep_M12B_propep - pfam01562 ZnMc_ADAM_like - cd04267 ZnMc - cd00203 Reprolysin - pfam01421 ZnMc_ADAMTS_like - cd04273 ZnMc_adamalysin_II_l - cd04269 ZnMc_salivary_gland_ - cd04272 ACR - smart00608 TSP1 - smart00209 TSP_1 - pfam00090 ADAM_spacer1 - pfam05986	Swiss-Prot Protein: Q9UP79 Identical to: NP_008968 Default View:

Domains found on the Protein

Domain ↕	CD Accession ↕	E-Value ↕	Start ↕	End ↕
ZnMc_ADAM_like	cd04267	2.2e-33	219	418
ZnMc_adamalysin_II_l	cd04269	6.3e-10	219	427
ZnMc_ADAMTS_like	cd04273	2.2e-107	219	426
ZnMc_salivary_gland_	cd04272	2.6e-07	220	426
Pep_M12B_propep	pfam01562	8.6e-33	19	151
Reprolysin	pfam01421	7.7e-13	219	429
TSP_1	pfam00090	1.1e-08	530	580
ACR	smart00608	1.3e-05	437	515
TSP1	smart00209	1.1e-15	529	581
ADAM_spacer1	pfam05986	2.5e-57	690	809
TSP1	smart00209	1e-08	835	888

Table of Mutations found on the Protein

Source ↕	Mut_ID ↕	Class ↕	HGVS ↕	Disease ↕
dbSNP	rs35468629	Polymorphism	p.ALA145GLY	N/A
dbSNP	rs2131535	Polymorphism	p.ALA525VAL	N/A
dbSNP	rs2291348	Polymorphism	p.ASN264SER	N/A
dbSNP	rs7927048	Polymorphism	p.GLU78ASP	N/A
dbSNP	rs11222085	Polymorphism	p.THR792ALA	N/A

Please Cite: Peterson, T.A., Adadey, A., Santana-Cruz ,I., Sun, Y., Winder A, Kann, M.G., (2010) DMDM: Domain Mapping of Disease Mutations. Bioinformatics 26 (19), 2458-2459.

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