Results for the protein: O00220

Results for the Protein: O00220

313104273

8797

TNFRSF10A

NCBI, UniProt

TR10A_HUMAN RecName: Full=Tumor necrosis factor receptor superfamily member 10A; AltName: Full=Death receptor 4; AltName: Full=TNF-related apoptosis-inducing ligand receptor 1; Short=TRAIL receptor 1; Short=TRAIL-R1; AltName: CD_antigen=CD261; Flags: Precursor

			0 8 0 7 1

Tips:

The Domains on the Default View are decided by the Domain's E-Value.

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Default View: TNFR - cd00185 TNFR_c6 - pfam00020 TNFR - smart00208 Death_TRAILR_DR4_DR5 - cd08315 DEATH - smart00005 Death_ank - cd08317 Death - pfam00531 Death_DRs - cd08784 Death - cd01670 Death_TNFR1 - cd08313 Death_TNFRSF25_DR3 - cd08815	Swiss-Prot Protein: O00220 Identical to: NP_003835 Default View:

Domains found on the Protein

Domain ↕	CD Accession ↕	E-Value ↕	Start ↕	End ↕
Death_TRAILR_DR4_DR5	cd08315	2.8e-61	359	454
Death_ank	cd08317	0.00026	362	449
Death	cd01670	3.3e-08	367	446
Death_TNFR1	cd08313	2.6e-06	367	445
Death_DRs	cd08784	6.5e-24	367	445
Death_TNFRSF25_DR3	cd08815	4.2e-05	368	445
TNFR_c6	pfam00020	1e-07	148	188
TNFR_c6	pfam00020	9.2e-06	190	229
Death	pfam00531	2.1e-19	366	448
TNFR	smart00208	2.5e-10	148	188
TNFR	smart00208	1.5e-12	190	229
DEATH	smart00005	4.5e-24	361	447

Table of Mutations found on the Protein

Source ↕	Mut_ID ↕	Class ↕	HGVS ↕	Disease ↕
dbSNP	rs2230229	Polymorphism	p.ARG441LYS	N/A
dbSNP	rs20575	Polymorphism	p.ARG209THR	N/A
dbSNP	rs17088980	Polymorphism	p.ASN297HIS	N/A
dbSNP	rs20576	Polymorphism	p.GLU228ALA	N/A
Swiss-Prot	VAR_052349	Polymorphism	p.GLY11VAL	N/A
dbSNP	rs17620	Polymorphism	p.HIS141ARG	N/A
dbSNP	rs11986840	Polymorphism	p.PRO105ARG	N/A
dbSNP	rs20577	Polymorphism	p.THR33ILE	N/A

Please Cite: Peterson, T.A., Adadey, A., Santana-Cruz ,I., Sun, Y., Winder A, Kann, M.G., (2010) DMDM: Domain Mapping of Disease Mutations. Bioinformatics 26 (19), 2458-2459.

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