Results for the protein: Q96GD4

Results for the Protein: Q96GD4

317373473

9212

AURKB

NCBI, UniProt

AURKB_HUMAN RecName: Full=Aurora kinase B; AltName: Full=Aurora 1; AltName: Full=Aurora- and IPL1-like midbody-associated protein 1; Short=AIM-1; AltName: Full=Aurora/IPL1-related kinase 2; Short=ARK-2; Short=Aurora-related kinase 2; AltName: Full=STK-1; AltName: Full=Serine/threonine-protein kinase 12; AltName: Full=Serine/threonine-protein kinase 5; AltName: Full=Serine/threonine-protein kinase aurora-B

			0 4 0 1 3

Tips:

The Domains on the Default View are decided by the Domain's E-Value.

Clicking a check box will display or hide the correlated domain.

To view the Gene page, either click on the link to the left or the blue bar above the Protein's graphic.

Swiss-Prot Protein: Q96GD4

Identical to: NP_004208

Default View:

Domains found on the Protein

Domain ↕	CD Accession ↕	E-Value ↕	Start ↕	End ↕
STKc_ROCK	cd05596	2.3e-10	35	343
STKc_ROCK1	cd05622	6.9e-08	37	343
STKc_JNK1	cd07875	0.001	42	341
STKc_PAK5	cd06658	4.8e-08	44	343
STKc_PAK4	cd06657	1.5e-07	45	333
STKc_PAK6	cd06659	8.6e-12	47	344
STKc_TAO1	cd06635	1.7e-06	54	341
STKc_TAO3	cd06633	4.6e-05	55	341
STKc_PAK_II	cd06648	2e-13	56	344
STKc_JNK2	cd07876	0.00055	56	344
PTKc_FGFR1	cd05098	3.5e-05	57	342
STKc_myosinIIIB	cd06639	2.2e-09	57	328
STKc_MAP4K4_6	cd06636	1.2e-06	60	327
PTKc_FGFR2	cd05101	3e-06	61	332
STKc_myosinIIIA	cd06638	2.2e-09	61	327
STKc_JNK	cd07850	1.9e-05	61	343
STKc_PAK	cd06614	9.3e-21	62	338
PKc_MKK7	cd06618	7.3e-10	63	344
STKc_PAK1	cd06654	2.6e-08	63	343
PTKc_FGFR4	cd05099	2.5e-06	64	338
PTKc_FGFR3	cd05100	0.00088	64	343
STKc_TAO	cd06607	3.1e-07	64	337
STKc_TAO2	cd06634	2.9e-07	64	342
STKc_PAK_I	cd06647	8.2e-17	64	344
STKc_PAK2	cd06655	3.4e-09	64	344
STKc_PAK3	cd06656	7.5e-09	64	344
STKc_p38	cd07851	1.3e-08	64	336
STKc_p38gamma_MAPK12	cd07880	3.6e-05	64	339
STKc_p38alpha_MAPK14	cd07877	0.00021	65	339
STKc_MAP4K5	cd06646	5.1e-09	66	326
STKc_STK10_LOK	cd06644	4.4e-16	66	343
STKc_CDK9	cd07865	8.4e-12	66	327
STKc_Sty1_Hog1	cd07856	4.2e-08	67	339
STKc_ASK	cd06624	5.4e-14	68	327
STKc_MAP4K3	cd06645	5.8e-10	68	326
PTKc_EGFR_like	cd05057	1.3e-05	69	337
STKc_CDK10	cd07845	6.3e-14	69	337
STKc_p38beta_MAPK11	cd07878	0.00058	69	342
PTKc_ALK_LTK	cd05036	2.5e-11	70	327
PTKc_FAK	cd05056	1.2e-09	70	332
PTK_CCK4	cd05046	4.2e-06	71	324
PTKc_Ror	cd05048	1.6e-06	71	326
PTKc_Trk	cd05049	3.8e-08	71	323
PTKc_Musk	cd05050	1e-08	71	328
PTKc_DDR	cd05051	0.00036	71	320
PTKc_Abl	cd05052	4.2e-08	71	329
PTKc_InsR	cd05061	4.2e-05	71	332
PTKc_IGF-1R	cd05062	3.1e-05	71	325
PTKc_EphR_A10	cd05064	0.0005	71	334
PTKc_Lck_Blk	cd05067	0.00023	71	325
PTKc_Frk_like	cd05068	4.4e-08	71	326
PTKc_Fyn_Yrk	cd05070	0.00011	71	328
PTKc_Lyn	cd05072	3.1e-06	71	326
PTKc_Hck	cd05073	2.2e-06	71	326
PTKc_Csk	cd05082	0.00011	71	328
PTKc_Tie2	cd05088	4.9e-08	71	342
PTKc_Ror1	cd05090	8e-06	71	330
PTKc_Ror2	cd05091	0.00033	71	330
PTKc_TrkA	cd05092	5.1e-08	71	333
PTKc_TrkB	cd05093	7.8e-07	71	337
PTKc_TrkC	cd05094	0.0001	71	337
PTKc_DDR2	cd05095	0.00011	71	327
PKc_MEK2	cd06649	3.6e-06	71	341
PKc_MEK1	cd06650	1.3e-06	71	344
STKc_CDK8_like	cd07842	2.8e-09	71	327
STKc_PCTAIRE_like	cd07844	1.2e-19	71	327
STKc_CDK12	cd07864	7.5e-16	71	327
STKc_PFTAIRE1	cd07869	2.7e-06	71	339
STKc_PFTAIRE2	cd07870	4.1e-09	71	327
STKc_PCTAIRE3	cd07871	7.6e-10	71	327
PTKc_InsR_like	cd05032	1.7e-07	72	325
PTKc_EphR	cd05033	6.5e-06	72	327
PTKc_Jak_rpt2	cd05038	1.5e-09	72	322
PTKc_FGFR	cd05053	2.1e-07	72	329
PTKc_EphR_B	cd05065	0.0001	72	328
PTKc_EphR_A	cd05066	3.3e-05	72	329
PTKc_Jak1_rpt2	cd05079	0.00025	72	329
PTKc_Tyk2_rpt2	cd05080	0.00014	72	324
PTKc_Jak2_Jak3_rpt2	cd05081	4.8e-07	72	330
PTKc_Chk	cd05083	0.00012	72	328
PTKc_Btk_Bmx	cd05113	7.3e-09	72	327
PTKc_Itk	cd05112	4.1e-08	72	322
PKc_MKK4	cd06616	2.7e-07	72	344
STKc_SLK	cd06643	4.4e-15	72	344
STKc_ERK1_2_like	cd07849	6.7e-08	72	344
STKc_ERK5	cd07855	8.6e-08	72	343
STKc_TEY_MAPK_plant	cd07858	9.7e-06	72	344
PTKc_EphR_A2	cd05063	5.6e-05	73	328
STKc_MAP4K3_like	cd06613	3.1e-16	73	326
STKc_CDC2L1	cd07843	1.4e-11	73	327
STKc_BUR1	cd07866	4.1e-13	73	327
STKc_PCTAIRE2	cd07872	6.3e-09	73	344
STKc_PCTAIRE1	cd07873	6.2e-09	73	337
PTKc_Csk_like	cd05039	2.5e-05	74	325
PTKc_Tec_like	cd05059	2.1e-09	74	322
PTKc_Tie1	cd05089	1.2e-08	74	344
PTKc_Tec_Rlk	cd05114	1.7e-08	74	326
STKc_SLK_like	cd06611	1.3e-13	74	342
STKc_TNIK	cd06637	8.5e-09	74	327
STKc_MAPK15	cd07852	2.4e-11	74	344
STKc_Nek6_Nek7	cd08224	1.2e-11	74	330
STKc_Nek6	cd08228	1.2e-08	74	327
STKc_Nek7	cd08229	4.1e-10	74	329
PTKc_Src_like	cd05034	1.6e-08	75	321
PTKc_Srm_Brk	cd05148	5.8e-09	75	324
STKc_ROCK_NDR_like	cd05573	2.7e-19	75	343
STKc_phototropin_lik	cd05574	5e-19	75	334
STKc_PKA	cd05580	6.5e-35	75	342
STKc_PDK1	cd05581	2.1e-62	75	327
STKc_DMPK_like	cd05597	2.5e-08	75	344
STKc_LATS	cd05598	7.6e-10	75	342
STKc_NDR_like	cd05599	3.2e-14	75	335
STKc_CRIK	cd05601	1.1e-14	75	343
STKc_MAST	cd05609	1.6e-15	75	341
STKc_Sid2p_Dbf2p	cd05600	1.7e-11	75	344
STKc_PRKX_like	cd05612	7e-45	75	344
STKc_MRCK_alpha	cd05623	1.6e-08	75	342
STKc_MRCK_beta	cd05624	5.9e-08	75	344
STKc_NDR2	cd05627	5.8e-08	75	343
STKc_NDR1	cd05628	4.1e-10	75	335
STKc_NDR_like_fungal	cd05629	7e-07	75	344
STKc_LATS2	cd05626	3.5e-05	75	344
PKc_MAPKK	cd06605	1e-13	75	331
STKc_myosinIII_like	cd06608	4e-14	75	327
STKc_MST3_like	cd06609	6.6e-19	75	344
STKc_OSR1_SPAK	cd06610	4.3e-15	75	327
STKc_MST1_2	cd06612	6.1e-15	75	327
PKc_MEK	cd06615	5.7e-12	75	344
PKc_MKK3_6	cd06617	2e-12	75	343
PKc_MKK5	cd06619	2.4e-06	75	339
PKc_MAPKK_Byr1_like	cd06620	5.1e-11	75	344
PKc_MAPKK_Pek1_like	cd06621	2.6e-11	75	335
PKc_MAPKK_plant_like	cd06623	1.1e-26	75	332
STKc_MEKK3_like	cd06625	4.6e-14	75	327
PKc_MAPKK_PBS2_like	cd06622	3.3e-09	75	343
STKc_MST4	cd06640	1.2e-09	75	344
STKc_MST3	cd06641	1.1e-08	75	344
STKc_STK25-YSK1	cd06642	1.9e-09	75	344
STKc_MEKK2	cd06652	4.3e-07	75	324
STKc_MEKK3_like_1	cd06653	2.8e-09	75	327
STKc_CDKL	cd07833	3.8e-14	75	327
STKc_CdkB_plant	cd07837	2.1e-12	75	328
STKc_CDKL2_3	cd07846	8.4e-11	75	327
STKc_CDKL1_4	cd07847	5.2e-18	75	327
STKc_CDKL5	cd07848	9.7e-08	75	327
STKc_CDK6	cd07862	7.3e-06	75	340
SPS1	COG0515	6.9e-46	75	342
PTKc_RET	cd05045	0.0003	76	311
PKc_STE	cd05122	1.6e-49	76	326
STKc_Yank1	cd05578	2.3e-34	76	327
STKc_MSK_N	cd05583	1.9e-34	76	340
STKc_cPKC	cd05587	4.4e-21	76	344
STKc_GRK4_like	cd05605	2e-13	76	342
STKc_MSK1_N	cd05613	3e-22	76	340
STKc_MSK2_N	cd05614	8.5e-16	76	344
STKc_cPKC_alpha	cd05615	1.4e-11	76	344
STKc_cPKC_beta	cd05616	7.4e-10	76	344
STKc_GRK6	cd05630	1.1e-08	76	342
STKc_GRK4	cd05631	1.9e-09	76	343
STKc_GRK5	cd05632	1.9e-08	76	342
STKc_MAPKKK	cd06606	6.2e-33	76	327
STKc_Cdc7_like	cd06627	1.6e-21	76	327
STKc_MAPKKK_Byr2_lik	cd06628	4.1e-27	76	327
STKc_MEKK1	cd06630	2.3e-11	76	328
STKc_YSK4	cd06631	7.3e-10	76	327
STKc_MEKK3	cd06651	5.9e-10	76	321
STKc_CCRK	cd07832	7.6e-18	76	328
STKc_MAPK	cd07834	6.9e-11	76	342
STKc_Pho85	cd07836	5.3e-19	76	327
STKc_CDK5	cd07839	6.5e-12	76	327
STKc_CDK7	cd07841	7.6e-17	76	341
STKc_NLK	cd07853	0.00046	76	343
STKc_MPK1	cd07857	9e-08	76	343
STKc_TDY_MAPK_plant	cd07859	5e-05	76	344
STKc_CDK2_3	cd07860	8.1e-17	76	327
STKc_CDK1_euk	cd07861	1.2e-19	76	327
STKc_CDK4	cd07863	6.5e-08	76	327
STKc_Nek	cd08215	3.3e-36	76	327
STKc_Nek2	cd08217	1.7e-16	76	327
STKc_Nek1	cd08218	6e-26	76	327
STKc_Nek3	cd08219	4.9e-21	76	327
STKc_Nek8	cd08220	4.1e-19	76	327
STKc_Nek9	cd08221	3.1e-12	76	327
STKc_Nek11	cd08222	1.2e-12	76	327
STKc_Nek4	cd08223	1.6e-12	76	327
STKc_Nek5	cd08225	5.8e-24	76	327
STKc_Nek10	cd08528	8.4e-13	76	327
STKc_FA2-like	cd08529	1.2e-14	76	324
STKc_CNK2-like	cd08530	6.7e-14	76	327
PTKc_Axl_like	cd05035	3.3e-06	77	329
PTKc_Yes	cd05069	0.00011	77	328
PTKc_Src	cd05071	0.00054	77	330
PTKc_Tyro3	cd05074	1.7e-06	77	329
PTKc_Axl	cd05075	0.0006	77	329
STKc_CMGC	cd05118	2.2e-17	77	327
STKc_PKN	cd05589	5.2e-19	77	344
STKc_LATS1	cd05625	2e-05	77	335
STKc_MAPKKK_Bck1_lik	cd06629	4.8e-12	77	327
STKc_CDK_like	cd07829	4.3e-20	77	327
STKc_MAK_like	cd07830	5.3e-14	77	327
STKc_CDK1_like	cd07835	1.6e-18	77	327
STKc_CDK4_6_like	cd07838	1.9e-11	77	327
STKc_CDK9_like	cd07840	5.6e-17	77	327
STKc_MAPK4_6	cd07854	1.7e-05	77	344
STKc_CDC2L6	cd07867	7.5e-07	77	327
STKc_CDK8	cd07868	2e-06	77	327
PK_STRAD	cd08216	4.8e-05	78	342
STKc_p70S6K	cd05584	9.2e-24	80	344
STKc_MEKK4	cd06626	3.7e-13	80	327
STKc_MEKK1_plant	cd06632	1.3e-15	80	327
PTKc	cd00192	6.7e-13	81	326
PTK_Jak_rpt1	cd05037	0.00029	81	322
PTKc_Ack_like	cd05040	1.3e-10	81	327
PTKc_Fes_like	cd05041	1.3e-10	81	327
PTKc_Aatyk	cd05042	0.00021	81	310
PTKc_c-ros	cd05044	6.5e-07	81	327
PTKc_Met_Ron	cd05058	8.1e-05	81	331
PTKc_Syk_like	cd05060	9.7e-07	81	323
PTKc_Fes	cd05084	3.6e-08	81	327
PTKc_Syk	cd05116	1.3e-07	81	332
STKc_PKB	cd05571	6.8e-24	81	344
STKc_SGK	cd05575	3.6e-17	81	344
STKc_PKC	cd05570	4.1e-19	81	343
STKc_RSK_N	cd05582	9e-26	81	343
STKc_aPKC	cd05588	4.5e-09	81	344
STKc_nPKC_eta	cd05590	3.8e-24	81	344
STKc_nPKC_epsilon	cd05591	7.5e-20	81	344
STKc_nPKC_theta_delt	cd05592	8.6e-20	81	344
STKc_PKB_gamma	cd05593	4.8e-12	81	343
STKc_PKB_alpha	cd05594	3.7e-13	81	344
STKc_PKB_beta	cd05595	6.1e-14	81	344
STKc_SGK1	cd05602	4.4e-10	81	344
STKc_SGK2	cd05603	9.9e-14	81	344
STKc_SGK3	cd05604	4.8e-11	81	344
STKc_aPKC_zeta	cd05617	2.7e-09	81	344
STKc_aPKC_iota	cd05618	4.6e-08	81	344
STKc_nPKC_theta	cd05619	1.7e-13	81	343
STKc_nPKC_delta	cd05620	7.5e-07	81	344
STKc_MOK	cd07831	1.8e-12	81	327
STKc_Rim15_like	cd05611	4.2e-11	82	329
PKc	cd00180	1.4e-79	83	325
PTKc_Tie	cd05047	5.4e-08	83	336
PTKc_Fer	cd05085	3.1e-07	83	327
PTKc_Zap-70	cd05115	6.7e-08	83	332
STKc_AGC	cd05123	1.1e-63	83	327
STKc_cGK_PKG	cd05572	7.9e-45	83	328
STKc_GRK	cd05577	1.3e-11	83	337
STKc_MAST_like	cd05579	3e-23	83	326
STKc_Sck1_like	cd05586	1.2e-08	83	344
STKc_YPK1_like	cd05585	1.7e-26	83	344
STKc_beta_ARK	cd05606	2.6e-09	83	341
STKc_GRK7	cd05607	6.7e-09	83	341
STKc_GRK1	cd05608	3.6e-12	83	342
STKc_GRK3	cd05633	3.3e-07	83	342
STKc_NAK1_like	cd06917	1.3e-14	83	344
Pkinase	pfam00069	4e-83	77	327
Pkinase_Tyr	pfam07714	1.1e-17	77	325
TyrKc	smart00219	4.9e-15	77	327
STYKc	smart00221	5.4e-85	77	327
S_TKc	smart00220	1.1e-94	87	327
KIND	smart00750	3.9e-05	174	337

Table of Mutations found on the Protein

Source ↕	Mut_ID ↕	Class ↕	HGVS ↕	Disease ↕
Swiss-Prot	VAR_040383	Polymorphism	p.ALA52VAL	N/A
Swiss-Prot	VAR_027970	Polymorphism	p.HIS100GLN	N/A
dbSNP	rs1059476	Polymorphism	p.MET298THR	N/A
Swiss-Prot	VAR_040384	Polymorphism	p.THR179MET	N/A

Please Cite: Peterson, T.A., Adadey, A., Santana-Cruz ,I., Sun, Y., Winder A, Kann, M.G., (2010) DMDM: Domain Mapping of Disease Mutations. Bioinformatics 26 (19), 2458-2459.

DMDM_info@umbc.edu | 1000 Hilltop Circle, Baltimore, MD 21250 | Department of Biological Sciences | Phone: 410-455-2258