Results for the protein: P17655

Results for the Protein: P17655

317373596

824

CAPN2

NCBI, UniProt

CAN2_HUMAN RecName: Full=Calpain-2 catalytic subunit; AltName: Full=Calcium-activated neutral proteinase 2; Short=CANP 2; AltName: Full=Calpain M-type; AltName: Full=Calpain large polypeptide L2; AltName: Full=Calpain-2 large subunit; AltName: Full=Millimolar-calpain; Short=M-calpain; Flags: Precursor

			0 6 0 0 6

Tips:

The Domains on the Default View are decided by the Domain's E-Value.

Clicking a check box will display or hide the correlated domain.

To view the Gene page, either click on the link to the left or the blue bar above the Protein's graphic.

Default View: CysPc - smart00230 CysPc - cd00044 Peptidase_C2 - pfam00648 Calpain_III - cd00214 Calpain_III - pfam01067 calpain_III - smart00720 EFh - cd00051	Swiss-Prot Protein: P17655 Default View:

Domains found on the Protein

Domain ↕	CD Accession ↕	E-Value ↕	Start ↕	End ↕
Calpain_III	cd00214	1.9e-97	354	512
EFh	cd00051	6.1e-05	576	632
Peptidase_C2	pfam00648	2.1e-241	45	344
Calpain_III	pfam01067	2.9e-93	355	508
CysPc	smart00230	2.3e-183	32	352
calpain_III	smart00720	1.2e-89	356	510

Table of Mutations found on the Protein

Source ↕	Mut_ID ↕	Class ↕	HGVS ↕	Disease ↕
Swiss-Prot	VAR_014435	Polymorphism	p.ASP22GLU	N/A
Swiss-Prot	VAR_021406	Polymorphism	p.GLU521GLN	N/A
Swiss-Prot	VAR_021405	Polymorphism	p.LYS476ARG	N/A
Swiss-Prot	VAR_014436	Polymorphism	p.LYS568GLN	N/A
Swiss-Prot	VAR_021407	Polymorphism	p.LYS677GLN	N/A
Swiss-Prot	VAR_021404	Polymorphism	p.SER68GLY	N/A

Please Cite: Peterson, T.A., Adadey, A., Santana-Cruz ,I., Sun, Y., Winder A, Kann, M.G., (2010) DMDM: Domain Mapping of Disease Mutations. Bioinformatics 26 (19), 2458-2459.

DMDM_info@umbc.edu | 1000 Hilltop Circle, Baltimore, MD 21250 | Department of Biological Sciences | Phone: 410-455-2258