Results for the protein: O95718

Results for the Protein: O95718

374095385

2103

ESRRB

NCBI, UniProt

ERR2_HUMAN RecName: Full=Steroid hormone receptor ERR2; AltName: Full=ERR beta-2; AltName: Full=Estrogen receptor-like 2; AltName: Full=Estrogen-related receptor beta; Short=ERR-beta; AltName: Full=Nuclear receptor subfamily 3 group B member 2

Known Diseases associated with this Protein:
DEAFNESS, AUTOSOMAL RECESSIVE, 35 (DFNB35)

4

2

0

0

6

Tips:

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Swiss-Prot Protein: O95718

Default View:

Domains found on the Protein

Domain ↕	CD Accession ↕	E-Value ↕	Start ↕	End ↕
NR_DBD_TLX	cd07163	1.7e-19	91	186
NR_DBD_ROR	cd06968	4.3e-24	93	193
NR_DBD_VDR	cd06955	1.9e-21	94	200
NR_DBD_PNR	cd06970	9.9e-19	95	185
NR_DBD_DHR4_like	cd07168	7.5e-35	95	184
NR_DBD_GCNF_like	cd07169	2.1e-32	96	184
NR_DBD_RAR	cd06964	4.4e-33	97	186
NR_DBD_ERR	cd07170	2.8e-73	97	193
NR_DBD_TR2_like	cd06967	1.2e-28	98	184
NR_DBD_REV_ERB	cd07166	4.2e-30	98	186
NR_DBD_ER	cd07171	1.2e-42	98	179
NR_DBD_AR	cd07173	2.3e-24	98	179
NR_DBD_GR_PR	cd07172	4e-24	99	176
NR_DBD_FXR	cd06962	1.9e-21	100	184
NR_DBD_EcR	cd07161	5.2e-22	100	189
NR_DBD_RXR	cd06956	2.4e-30	101	177
NR_DBD_CAR	cd06966	1.2e-23	101	192
NR_DBD_NGFI-B	cd06969	1.3e-35	101	175
2DBD_NR_DBD1	cd07157	1.5e-18	101	184
NR_DBD_EcR_like	cd06959	1.1e-25	102	174
NR_DBD_TR	cd06961	9e-38	102	186
NR_DBD_Ppar	cd06965	4.9e-26	102	185
NR_DBD_PXR	cd07162	8.9e-26	102	188
NR_DBD_like	cd06916	8e-48	103	174
NR_DBD_PNR_like_2	cd06957	3.5e-20	103	185
NR_DBD_COUP_TF	cd06958	1e-26	103	175
NR_DBD_HNF4A	cd06960	2.5e-36	103	178
NR_DBD_GR_like	cd06963	4e-26	103	175
NR_DBD_PNR_like	cd07154	1.6e-26	103	174
NR_DBD_ER_like	cd07155	3.5e-49	103	177
NR_DBD_VDR_like	cd07156	4.9e-34	103	174
NR_DBD_Ppar_like	cd07158	3.8e-33	103	174
NR_DBD_PNR_like_1	cd07164	2e-27	103	180
NR_DBD_DmE78_like	cd07165	2.4e-32	103	184
NR_DBD_Lrh-1_like	cd07167	7.8e-42	103	195
2DBD_NR_DBD2	cd07179	6.3e-28	103	176
NR_LBD_VDR	cd06933	4.2e-05	141	433
NR_LBD_TR	cd06935	4.8e-06	181	428
NR_LBD_DHR38_like	cd07072	1.9e-08	204	435
NR_LBD_EcR	cd06938	1.8e-05	205	431
NR_LBD_NGFI-B	cd07348	1.5e-10	205	431
NR_LBD_RXR_like	cd06943	2.9e-16	206	414
NR_LBD_ER	cd06949	2.2e-52	207	432
NR_LBD_Nurr1_like	cd06945	1.2e-11	208	431
NR_LBD_COUP-TF	cd06948	1.5e-12	208	448
NR_LBD_PXR_like	cd06934	0.00076	209	428
NR_LBD_Ftz-F1_like	cd06944	1.2e-14	209	432
NR_LBD_Lrh-1	cd07069	1.1e-16	209	434
NR_LBD_SF-1	cd07070	5.5e-14	209	432
NR_LBD_LXR	cd06954	0.00012	210	419
NR_LBD_Nurr1	cd07071	5.3e-07	210	431
NR_LBD_RAR	cd06937	2.5e-10	211	431
NR_LBD_GR_Like	cd06947	4.6e-11	211	507
NR_LBD_PR	cd07074	3.7e-07	211	450
NR_LBD_MR	cd07075	0.00013	211	508
NR_LBD_GR	cd07076	3e-08	211	453
NR_LBD_HNF4_like	cd06931	2.2e-20	212	428
NR_LBD_ERR	cd06946	2.3e-154	212	431
NR_LBD_ER_like	cd07068	4.2e-135	212	431
NR_LBD_AR	cd07073	8.7e-07	212	448
NR_LBD_Tlx_PNR_like	cd06950	4.1e-11	213	418
NR_LBD_DHR4_like	cd06953	9.1e-07	215	427
NR_LBD_Fxr	cd06936	0.00081	219	430
NR_LBD_Dax1	cd07350	2e-05	219	427
NR_LBD_Dax1_like	cd06951	7.9e-07	221	427
NR_LBD_REV_ERB	cd06940	0.00021	232	415
NR_LBD_TR2_like	cd06952	1.5e-05	232	428
NR_LBD_F1	cd06929	6.7e-18	237	410
NR_LBD_ROR_like	cd06939	0.00055	237	425
NR_LBD_DmE78_like	cd06941	1.1e-05	237	430
NR_LBD_F2	cd06930	1e-49	240	402
NR_LBD	cd06157	8.3e-42	241	402
zf-C4	pfam00105	1.4e-46	101	170
Hormone_recep	pfam00104	6.6e-46	271	428
ZnF_C4	smart00399	2.3e-41	102	171
HOLI	smart00430	5.5e-36	247	402

Table of Mutations found on the Protein

Source ↕	Mut_ID ↕	Class ↕	HGVS ↕	Disease ↕
Swiss-Prot	VAR_043503	Disease	p.ALA110VAL	Deafness, autosomal recessive, 35 (DFNB35)
Swiss-Prot	VAR_043504	Disease	p.LEU320PRO	Deafness, autosomal recessive, 35 (DFNB35)
Swiss-Prot	VAR_043506	Disease	p.LEU347PRO	Deafness, autosomal recessive, 35 (DFNB35)
Swiss-Prot	VAR_043507	Polymorphism	p.PRO386SER	N/A
Swiss-Prot	VAR_043508	Polymorphism	p.THR389MET	N/A
Swiss-Prot	VAR_043505	Disease	p.VAL342LEU	Deafness, autosomal recessive, 35 (DFNB35)

Please Cite: Peterson, T.A., Adadey, A., Santana-Cruz ,I., Sun, Y., Winder A, Kann, M.G., (2010) DMDM: Domain Mapping of Disease Mutations. Bioinformatics 26 (19), 2458-2459.

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