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Results for the Protein: NP_001244316
383792178

serine/threonine-protein kinase Chk2 isoform d [Homo sapiens]

Known Diseases associated with this Protein:
  BREAST CANCER, SUSCEPTIBILITY TO
1
0
1
0
0
Tips:
 The Domains on the Default View are decided by the Domain's E-Value.

 Clicking a check box will display or hide the correlated domain.

 To view the Gene page, either click on the link to the left or the blue bar above the Protein's graphic.



Default View:

STKc_CDK1_like - cd07835
STKc_CDK5 - cd07839
STKc_CCRK - cd07832
STKc_MAK_like - cd07830
STKc_PAK2 - cd06655
STKc_PAK5 - cd06658
STKc_CDK7 - cd07841
STKc_CDK8_like - cd07842
STKc_NLK - cd07853
STKc_ERK5 - cd07855
STKc_MAPK15 - cd07852
STKc_p38 - cd07851
STKc_CDKL2_3 - cd07846
STKc_CDKL5 - cd07848
STKc_MEKK3_like_1 - cd06653
STKc_MEKK2 - cd06652
STKc_myosinIIIA - cd06638
STKc_myosinIIIB - cd06639
STKc_TNIK - cd06637
STKc_MAP4K4_6 - cd06636
STKc_MAPKKK_Byr2_lik - cd06628
STKc_MEKK1_plant - cd06632
STKc_STK25-YSK1 - cd06642
STKc_SLK - cd06643
STKc_PAK_I - cd06647
STKc_MEKK3 - cd06651
STKc_MAP4K5 - cd06646
STKc_MAP4K3 - cd06645
STKc_STK10_LOK - cd06644
STKc_MPK1 - cd07857
STKc_TEY_MAPK_plant - cd07858
STKc_Nek6 - cd08228
STKc_Nek7 - cd08229
STKc_Nek5 - cd08225
STKc_Nek6_Nek7 - cd08224
STKc_Nek11 - cd08222
STKc_Nek4 - cd08223
STKc_Nek10 - cd08528
STKc_FA2-like - cd08529
PTKc_InsR_like - cd05032
Pkinase_Tyr - pfam07714
TyrKc - smart00219
STYKc - smart00221
SPS1 - COG0515
STKc_Nek3 - cd08219
PK_STRAD - cd08216
STKc_PCTAIRE3 - cd07871
STKc_PCTAIRE2 - cd07872
STKc_BUR1 - cd07866
STKc_CDK12 - cd07864
STKc_TDY_MAPK_plant - cd07859
STKc_CDK6 - cd07862
STKc_PCTAIRE1 - cd07873
STKc_JNK1 - cd07875
STKc_p38delta_MAPK13 - cd07879
STKc_p38gamma_MAPK12 - cd07880
STKc_p38beta_MAPK11 - cd07878
STKc_p38alpha_MAPK14 - cd07877
STKc_ERK1_2_like - cd07849
STKc_ASK - cd06624
STKc_Cdc7_like - cd06627
PTKc_Tyk2_rpt2 - cd05080
PTKc_Hck - cd05073
PTKc_Tyro3 - cd05074
PTKc_Lyn - cd05072
PTKc_Frk_like - cd05068
PTKc_Yes - cd05069
PTKc_Csk - cd05082
PTKc_Chk - cd05083
PTKc_Itk - cd05112
PTKc_Btk_Bmx - cd05113
PTK_HER3 - cd05111
PTKc_Tie1 - cd05089
PTKc_Tie2 - cd05088
PTKc_Lck_Blk - cd05067
PTKc_Ror - cd05048
PTKc_Jak_rpt2 - cd05038
PTKc_Csk_like - cd05039
PTKc_ALK_LTK - cd05036
PTKc_Axl_like - cd05035
PTKc_EphR - cd05033
PTKc_Src_like - cd05034
PTKc_RET - cd05045
PTKc_Trk - cd05049
PTKc_EGFR_like - cd05057
PTKc_Tec_like - cd05059
PTKc_FAK - cd05056
PTKc_FGFR - cd05053
PTKc_Abl - cd05052
PTKc_EGFR - cd05108
PTKc_Tec_Rlk - cd05114
STKc_MAPKKK - cd06606
STKc_myosinIII_like - cd06608
PKc_MAPKK - cd06605
STKc_MRCK_beta - cd05624
STKc_ROCK1 - cd05622
STKc_MRCK_alpha - cd05623
STKc_OSR1_SPAK - cd06610
STKc_MAP4K3_like - cd06613
PKc_MAPKK_Pek1_like - cd06621
PKc_MAPKK_plant_like - cd06623
PKc_MKK5 - cd06619
PKc_MKK7 - cd06618
PKc_MEK - cd06615
STKc_ROCK2 - cd05621
STKc_cPKC_beta - cd05616
STKc_MSK_N - cd05583
STKc_ROCK - cd05596
STKc_PKN - cd05589
STKc_cPKC - cd05587
PTKc_Srm_Brk - cd05148
STKc_Yank1 - cd05578
STKc_CRIK - cd05601
STKc_DMPK_like - cd05597
STKc_cPKC_alpha - cd05615
STKc_GRK4_like - cd05605
STKc_MSK2_N - cd05614
STKc_PRKX_like - cd05612
STKc_MSK1_N - cd05613
STKc_MAST - cd05609
STKc_CDK9 - cd07865
Pkinase - pfam00069
STKc_CDK4_6_like - cd07838
STKc_p70S6K - cd05584
STKc_MEKK4 - cd06626
STKc_MST3_like - cd06609
STKc_PAK - cd06614
PKc_STE - cd05122
STKc_RSK_N - cd05582
STKc_PAK1 - cd06654
STKc_MST4 - cd06640
STKc_PAK3 - cd06656
STKc_MST3 - cd06641
STKc_MOK - cd07831
STKc_MAPK - cd07834
STKc_TAO1 - cd06635
STKc_CDK_like - cd07829
STKc_TAO2 - cd06634
STKc_MEKK1 - cd06630
PKc_MKK3_6 - cd06617
STKc_TAO - cd06607
STKc_NDR_like - cd05599
PKc_MAPKK_Byr1_like - cd06620
PKc_MAPKK_PBS2_like - cd06622
STKc_YSK4 - cd06631
STKc_Pho85 - cd07836
STKc_MEKK3_like - cd06625
STKc_TAO3 - cd06633
STKc_PCTAIRE_like - cd07844
STKc_JNK2 - cd07876
STKc_JNK3 - cd07874
STKc_PFTAIRE2 - cd07870
STKc_Nek - cd08215
STKc_Nek2 - cd08217
STKc_CNK2-like - cd08530
STKc_Nek8 - cd08220
STKc_Nek1 - cd08218
STKc_PFTAIRE1 - cd07869
STKc_CDK4 - cd07863
STKc_CDKL1_4 - cd07847
STKc_nPKC_epsilon - cd05591
STKc_CDK9_like - cd07840
STKc_JNK - cd07850
STKc_MAPK4_6 - cd07854
STKc_CDK1_euk - cd07861
STKc_CDK2_3 - cd07860
STKc_Sty1_Hog1 - cd07856
STKc_CdkB_plant - cd07837
STKc_PAK_II - cd06648
STKc_PKB - cd05571
STKc_PKC - cd05570
STKc_CMGC - cd05118
PTKc_Syk - cd05116
STKc_ROCK_NDR_like - cd05573
STKc_phototropin_lik - cd05574
STKc_aPKC - cd05588
STKc_SGK - cd05575
STKc_PKA - cd05580
PTKc_HER4 - cd05110
PTKc_HER2 - cd05109
PTKc_c-ros - cd05044
PTKc_Fes_like - cd05041
PTKc_Ack_like - cd05040
PTKc - cd00192
PTKc_Syk_like - cd05060
PTKc_Jak1_rpt2 - cd05079
PTKc_Fes - cd05084
STKc_GRK5 - cd05632
PTKc_Jak2_Jak3_rpt2 - cd05081
STKc_nPKC_eta - cd05590
PTKc_Fer - cd05085
STKc_LATS2 - cd05626
STKc_LATS1 - cd05625
STKc_nPKC_delta - cd05620
STKc_nPKC_theta - cd05619
STKc_NDR2 - cd05627
STKc_GRK4 - cd05631
STKc_NDR1 - cd05628
STKc_NDR_like_fungal - cd05629
STKc_GRK6 - cd05630
STKc_nPKC_theta_delt - cd05592
STKc_aPKC_iota - cd05618
STKc_LATS - cd05598
STKc_PKB_beta - cd05595
STKc_PKB_alpha - cd05594
STKc_PKB_gamma - cd05593
STKc_aPKC_zeta - cd05617
STKc_SGK1 - cd05602
STKc_Rim15_like - cd05611
STKc_SGK2 - cd05603
STKc_PDK1 - cd05581
STKc_SGK3 - cd05604
STKc_CDC2L6 - cd07867
STKc_Nek9 - cd08221
STKc_CDKL - cd07833
PKc_MKK4 - cd06616
STKc_NAK1_like - cd06917
STKc_GRK3 - cd05633
STKc_beta_ARK - cd05606
STKc_PAK6 - cd06659
STKc_PAK4 - cd06657
PTKc_Zap-70 - cd05115
STKc_SLK_like - cd06611
STKc_MST1_2 - cd06612
STKc_GRK7 - cd05607
STKc_GRK1 - cd05608
PKc - cd00180
STKc_Sid2p_Dbf2p - cd05600
STKc_AGC - cd05123
STKc_cGK_PKG - cd05572
STKc_MAST_like - cd05579
STKc_Sck1_like - cd05586
STKc_YPK1_like - cd05585
STKc_GRK - cd05577
STKc_MAPKKK_Bck1_lik - cd06629
STKc_CDK10 - cd07845
S_TKc - smart00220
STKc_CDC2L1 - cd07843
STKc_CDK8 - cd07868
KIND - smart00750




Domains found on the Protein

Domain ↕CD Accession ↕E-Value ↕Start ↕End ↕
PTKc_InsR_likecd050320.000131267
PTKc_EphRcd050331.7e-051246
PTKc_Src_likecd050343.3e-061242
PTKc_Axl_likecd050350.000421260
PTKc_ALK_LTKcd050363.5e-091247
PTKc_Jak_rpt2cd050382.6e-081249
PTKc_Csk_likecd050390.000961216
PTKc_RETcd050450.000581249
PTKc_Trkcd050495.4e-051262
PTKc_Ablcd050525.6e-061264
PTKc_FGFRcd050530.000571246
PTKc_FAKcd050565.9e-071269
PTKc_EGFR_likecd050573e-051293
PTKc_Tec_likecd050592e-061246
PTKc_Rorcd050480.000791248
PTKc_Lck_Blkcd050674.3e-051284
PTKc_Frk_likecd050681.3e-051270
PTKc_Yescd050690.000211268
PTKc_Lyncd050722.9e-051249
PTKc_Tyro3cd050740.000521264
PTKc_Tyk2_rpt2cd050801.3e-051279
PTKc_Hckcd050731.8e-051251
PTKc_Cskcd050827.3e-051268
PTKc_Chkcd050830.000671268
PTKc_Tie2cd050880.000741289
PTKc_Tie1cd050890.000641288
PTK_HER3cd051110.000131277
PTKc_Itkcd051122.9e-061264
PTKc_Btk_Bmxcd051136e-061264
PTKc_EGFRcd051080.000131315
PTKc_Tec_Rlkcd051143.4e-061264
PTKc_Srm_Brkcd051484.5e-071242
STKc_Yank1cd055785.6e-321265
STKc_cPKCcd055871.9e-121321
STKc_PKNcd055892.2e-121312
STKc_MSK_Ncd055832.4e-231288
STKc_ROCKcd055968.3e-081321
STKc_DMPK_likecd055977.5e-091322
STKc_CRIKcd056013.6e-111322
STKc_MASTcd056099e-221300
STKc_MSK1_Ncd056131.2e-181288
STKc_MSK2_Ncd056148.3e-161310
STKc_PRKX_likecd056124.9e-331303
STKc_cPKC_alphacd056155.9e-091318
STKc_GRK4_likecd056052.4e-131303
STKc_cPKC_betacd056168.6e-081313
STKc_ROCK2cd056215.9e-091322
STKc_ROCK1cd056229.5e-071322
STKc_MRCK_alphacd056231.9e-081321
STKc_MRCK_betacd056249.6e-081322
PKc_MAPKKcd066053.3e-121270
STKc_MAPKKKcd066062.1e-461265
STKc_myosinIII_likecd066081.4e-131265
STKc_OSR1_SPAKcd066108.2e-141265
STKc_MAP4K3_likecd066131.3e-141264
PKc_MEKcd066151e-081282
PKc_MKK7cd066182.4e-081280
PKc_MKK5cd066190.000121282
PKc_MAPKK_Pek1_likecd066214.4e-081278
PKc_MAPKK_plant_likecd066231.7e-221270
STKc_ASKcd066244.9e-201265
STKc_Cdc7_likecd066274.2e-221265
STKc_MAPKKK_Byr2_likcd066281.4e-221265
STKc_MEKK1_plantcd066324.1e-171265
STKc_MAP4K4_6cd066369e-061265
STKc_TNIKcd066371.6e-071265
STKc_myosinIIIAcd066384.6e-101265
STKc_myosinIIIBcd066395.1e-101266
STKc_STK25-YSK1cd066421.5e-091286
STKc_SLKcd066432.2e-101283
STKc_STK10_LOKcd066442.6e-091285
STKc_MAP4K3cd066451.1e-081264
STKc_MAP4K5cd066465.1e-081264
STKc_PAK_Icd066473.3e-111286
STKc_MEKK3cd066514.1e-191267
STKc_MEKK2cd066521.2e-131266
STKc_MEKK3_like_1cd066533.3e-171265
STKc_PAK2cd066553.7e-091289
STKc_PAK5cd066586.2e-081282
STKc_MAK_likecd078302.5e-181265
STKc_CCRKcd078321.3e-171266
STKc_CDK1_likecd078351e-111265
STKc_CDK5cd078394.7e-101265
STKc_CDK7cd078411.8e-161278
STKc_CDK8_likecd078422.1e-121265
STKc_CDKL2_3cd078462.7e-101265
STKc_CDKL5cd078482.8e-061265
STKc_p38cd078512e-141301
STKc_MAPK15cd078523.2e-171282
STKc_NLKcd078533.6e-111322
STKc_ERK5cd078551.9e-151294
STKc_MPK1cd078572.7e-121295
STKc_TEY_MAPK_plantcd078588.4e-251300
STKc_TDY_MAPK_plantcd078597e-141321
STKc_CDK6cd078620.000281265
STKc_CDK12cd078645.7e-111265
STKc_BUR1cd078665.8e-141265
STKc_PCTAIRE3cd078711.2e-061265
STKc_PCTAIRE2cd078722.1e-051288
STKc_PCTAIRE1cd078732e-051276
STKc_JNK1cd078754.7e-081294
STKc_ERK1_2_likecd078491.1e-141293
STKc_p38alpha_MAPK14cd078771.2e-091294
STKc_p38beta_MAPK11cd078785.5e-091300
STKc_p38delta_MAPK13cd078791.5e-061301
STKc_p38gamma_MAPK12cd078808.7e-111301
PK_STRADcd082160.000181280
STKc_Nek3cd082196.9e-161265
STKc_Nek11cd082229.9e-261265
STKc_Nek4cd082231.3e-231265
STKc_Nek6_Nek7cd082241.1e-101272
STKc_Nek5cd082253e-191265
STKc_Nek6cd082286.9e-131260
STKc_Nek7cd082291.1e-101263
STKc_Nek10cd085281.1e-131264
STKc_FA2-likecd085298.1e-151265
SPS1COG05153.9e-451318
PKc_STEcd051225.5e-312264
STKc_RSK_Ncd055823.1e-172321
STKc_p70S6Kcd055847.2e-252320
STKc_MST3_likecd066097.9e-152286
STKc_PAKcd066144.1e-212278
STKc_MEKK4cd066262.8e-192265
STKc_CDK4_6_likecd078382.9e-142265
STKc_CDK9cd078653e-112265
PTKccd001922.2e-093246
PTKc_Ack_likecd050407.7e-083247
PTKc_Fes_likecd050411.2e-083244
PTKc_c-roscd050441.6e-063248
PTKc_Syk_likecd050605.9e-073251
PTKc_Jak1_rpt2cd050790.000273285
PTKc_Jak2_Jak3_rpt2cd050817.1e-063285
PTKc_Fercd050856.8e-053265
PTKc_Fescd050841.2e-053267
PTKc_HER2cd051090.000743258
PTKc_HER4cd051100.000313282
PTKc_Sykcd051161.7e-083265
STKc_CMGCcd051183.5e-223265
STKc_PKCcd055701.5e-153312
STKc_PKBcd055712e-263322
STKc_ROCK_NDR_likecd055732.1e-183313
STKc_phototropin_likcd055743e-173273
STKc_PKAcd055803.7e-253312
STKc_SGKcd055759.1e-113322
STKc_aPKCcd055882.4e-123313
STKc_nPKC_etacd055901.1e-113319
STKc_nPKC_theta_deltcd055926.3e-153320
STKc_PKB_gammacd055937.4e-123310
STKc_PKB_alphacd055944.1e-133320
STKc_PKB_betacd055952.6e-143320
STKc_LATScd055985.7e-103317
STKc_SGK1cd056022e-093318
STKc_SGK2cd056032.8e-123321
STKc_SGK3cd056046.3e-113322
STKc_PDK1cd055812.8e-393265
STKc_Rim15_likecd056111.7e-103267
STKc_aPKC_zetacd056172.3e-103313
STKc_aPKC_iotacd056183e-093313
STKc_nPKC_thetacd056192.6e-113320
STKc_nPKC_deltacd056206.5e-063315
STKc_LATS1cd056259.4e-073317
STKc_LATS2cd056263.2e-063317
STKc_NDR2cd056275.6e-073316
STKc_NDR1cd056282.4e-093316
STKc_NDR_like_fungalcd056294.3e-073321
STKc_GRK6cd056307.4e-093286
STKc_GRK4cd056312.1e-093290
STKc_GRK5cd056323.4e-103286
STKc_nPKC_epsiloncd055913.8e-133319
STKc_NDR_likecd055991e-123304
STKc_TAOcd066079.3e-073293
PKc_MKK3_6cd066174.9e-083283
PKc_MAPKK_Byr1_likecd066202.4e-073281
PKc_MAPKK_PBS2_likecd066229.8e-103313
STKc_MEKK3_likecd066251.2e-233265
STKc_MEKK1cd066301.4e-103266
STKc_YSK4cd066319.6e-123265
STKc_TAO3cd066330.000153293
STKc_TAO1cd066358.5e-063293
STKc_MST4cd066408.7e-083286
STKc_MST3cd066417.4e-083286
STKc_PAK_IIcd066482.1e-133278
STKc_PAK1cd066544.7e-083288
STKc_PAK3cd066562.6e-083290
STKc_TAO2cd066341.7e-073303
STKc_CDK_likecd078294.7e-203265
STKc_MOKcd078312.6e-163265
STKc_MAPKcd078341.3e-183299
STKc_Pho85cd078363.9e-163265
STKc_CdkB_plantcd078374.6e-133266
STKc_CDK9_likecd078402e-173265
STKc_PCTAIRE_likecd078441.7e-073265
STKc_CDKL1_4cd078471.5e-103265
STKc_JNKcd078501.1e-103306
STKc_MAPK4_6cd078542.9e-123300
STKc_Sty1_Hog1cd078561.2e-113296
STKc_CDK2_3cd078607.8e-123265
STKc_CDK1_eukcd078619.4e-173265
STKc_CDK4cd078631.7e-083265
STKc_PFTAIRE1cd078690.000113279
STKc_PFTAIRE2cd078704.1e-073265
STKc_JNK3cd078748e-093318
STKc_JNK2cd078767.6e-093292
STKc_Nekcd082153.6e-413265
STKc_Nek2cd082176.5e-163265
STKc_Nek1cd082181.9e-213265
STKc_Nek8cd082205.6e-253265
STKc_CNK2-likecd085302e-143265
PTKc_Zap-70cd051151.6e-064265
STKc_beta_ARKcd056065.2e-104285
STKc_GRK3cd056333.6e-084290
PKc_MKK4cd066161.2e-074278
STKc_PAK4cd066571.4e-074284
STKc_PAK6cd066597.2e-114288
STKc_NAK1_likecd069174.9e-114282
STKc_CDKLcd078331.2e-144265
STKc_CDC2L6cd078671.7e-064265
STKc_Nek9cd082215.8e-144265
PKccd001802.8e-795263
STKc_AGCcd051236.5e-465265
STKc_cGK_PKGcd055726.3e-295272
STKc_GRKcd055774.5e-125279
STKc_MAST_likecd055792.1e-235270
STKc_YPK1_likecd055857.2e-245321
STKc_Sck1_likecd055863e-135322
STKc_Sid2p_Dbf2pcd056005.7e-115322
STKc_GRK7cd056073.5e-095285
STKc_GRK1cd056087.7e-115294
STKc_SLK_likecd066112.3e-145280
STKc_MST1_2cd066122.9e-185265
STKc_MAPKKK_Bck1_likcd066291.6e-126265
STKc_CDK10cd078456.8e-128275
STKc_CDC2L1cd078434.3e-1610265
STKc_CDK8cd078686.1e-0616265
Pkinasepfam000692.4e-892265
Pkinase_Tyrpfam077145.3e-161245
TyrKcsmart002191.9e-131265
STYKcsmart002215.6e-881265
S_TKcsmart002204.9e-1019265
KINDsmart007500.0001486273

Table of Mutations found on the Protein

Source ↕Mut_ID ↕Class ↕HGVS ↕Disease ↕
OMIM604373.0014 Diseasep.SER164PHEBREAST CANCER, SUSCEPTIBILITY TO



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