Results for the protein: NP

Results for the Protein: NP_001020332

392513723

1565

CYP2D6

NCBI

cytochrome P450 2D6 isoform 2 [Homo sapiens]

Known Diseases associated with this Protein:
DEBRISOQUINE, POOR METABOLISM OF
DEBRISOQUINE, ULTRARAPID METABOLISM OF

4

13

4

13

0

Tips:

The Domains on the Default View are decided by the Domain's E-Value.

Clicking a check box will display or hide the correlated domain.

To view the Gene page, either click on the link to the left or the blue bar above the Protein's graphic.

Default View: CypX - COG2124 p450 - pfam00067	RefSeq Protein: NP_001020332 Default View:

Domains found on the Protein

Domain ↕	CD Accession ↕	E-Value ↕	Start ↕	End ↕
p450	pfam00067	2.7e-136	34	443

Source ↕	Mut_ID ↕	Class ↕	HGVS ↕	Disease ↕
dbSNP	rs1058172	Polymorphism	p.ARG314HIS	N/A
dbSNP	rs16947	Polymorphism	p.CYS245ARG	N/A
dbSNP	rs61736517	Polymorphism	p.HIS301ARG	N/A
dbSNP	rs28371704	Polymorphism	p.HIS94ARG	N/A
dbSNP	rs28371703	Polymorphism	p.LEU91MET	N/A
dbSNP	rs17002853	Polymorphism	p.LEU180PRO	N/A
dbSNP	rs61736514	Polymorphism	p.LEU244VAL	N/A
dbSNP	rs1065852	Polymorphism	p.PRO34SER	N/A
dbSNP	rs1135830	Polymorphism	p.SER260LEU	N/A
dbSNP	rs28371706	Polymorphism	p.THR107ILE	N/A
dbSNP	rs1135840	Polymorphism	p.THR435SER	N/A
dbSNP	rs61745683	Polymorphism	p.VAL319ILE	N/A
dbSNP	rs59421388	Polymorphism	p.VAL287MET	N/A
OMIM	124030.0007	Disease	p.ARG245CYS	DEBRISOQUINE, ULTRARAPID METABOLISM OF
OMIM	124030.0004	Disease	p.GLY1TER	DEBRISOQUINE, POOR METABOLISM OF
OMIM	124030.0005	Disease	p.PRO34SER	DEBRISOQUINE, POOR METABOLISM OF
OMIM	124030.0007	Disease	p.SER435THR	DEBRISOQUINE, ULTRARAPID METABOLISM OF

DMDM_info@umbc.edu | 1000 Hilltop Circle, Baltimore, MD 21250 | Department of Biological Sciences | Phone: 410-455-2258