Results for the protein: NP

Results for the Protein: NP_003812

4506537

8767

RIPK2

NCBI

receptor-interacting serine/threonine-protein kinase 2 [Homo sapiens]

			0 1 0 1 0

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RefSeq Protein: NP_003812

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Domains found on the Protein

Domain ↕	CD Accession ↕	E-Value ↕	Start ↕	End ↕
STKc_TAO	cd06607	5.4e-05	2	335
STKc_TAO2	cd06634	1.4e-05	2	332
STKc_PAK1	cd06654	0.00016	2	304
STKc_PAK_I	cd06647	0.0001	3	302
STKc_PAK_II	cd06648	0.00016	3	288
STKc_PAK2	cd06655	0.00029	3	305
STKc_PAK3	cd06656	0.00014	3	319
STKc_PAK	cd06614	4.2e-09	4	287
PKc_MKK7	cd06618	1.7e-07	5	309
STKc_Sty1_Hog1	cd07856	9.2e-05	6	319
PTKc_FGFR4	cd05099	1.3e-05	7	319
STKc_MAP4K5	cd06646	0.00018	8	291
PTKc_Ror2	cd05091	1.7e-05	9	297
PTKc_FGFR2	cd05101	0.00077	9	299
STKc_ASK	cd06624	6.9e-08	9	294
STKc_CDK9	cd07865	0.00067	9	283
PTKc_FGFR	cd05053	1.2e-05	10	295
PTKc_EGFR_like	cd05057	6.5e-08	10	301
PTKc_Tie2	cd05088	1.1e-07	10	309
PTKc_FGFR3	cd05100	0.00084	10	331
PTKc_EGFR	cd05108	1.6e-07	10	341
PTKc_HER2	cd05109	8.6e-08	10	304
PTKc_HER4	cd05110	6.2e-05	10	328
PTKc_ALK_LTK	cd05036	3.8e-11	11	292
STKc_MEKK2	cd06652	0.00018	11	285
PTK_CCK4	cd05046	2.6e-08	12	292
PTKc_Ror	cd05048	1.2e-08	12	287
PTKc_Musk	cd05050	4.4e-11	12	292
PTKc_DDR	cd05051	1.3e-08	12	292
PTKc_Trk	cd05049	8.1e-12	12	296
PTKc_FAK	cd05056	6.5e-10	12	298
PTKc_InsR	cd05061	4.6e-08	12	302
PTKc_IGF-1R	cd05062	7.1e-07	12	292
PTKc_EphR_A2	cd05063	2.1e-07	12	294
PTKc_EphR_A10	cd05064	2.2e-07	12	294
PTKc_EphR_B	cd05065	2.5e-08	12	294
PTKc_Lck_Blk	cd05067	5.5e-06	12	291
PTKc_Frk_like	cd05068	5.9e-20	12	293
PTKc_Yes	cd05069	2e-08	12	293
PTKc_Fyn_Yrk	cd05070	5.2e-07	12	291
PTKc_Src	cd05071	1.2e-06	12	295
PTKc_Lyn	cd05072	7.6e-08	12	297
PTKc_Hck	cd05073	3.8e-07	12	293
PTKc_Ror1	cd05090	2.5e-06	12	293
PTKc_TrkA	cd05092	4.8e-08	12	296
PTKc_TrkB	cd05093	1.7e-07	12	296
PTKc_Abl	cd05052	7.5e-09	12	294
PTKc_DDR1	cd05096	3.2e-05	12	292
PTKc_DDR_like	cd05097	7.6e-07	12	292
PTK_HER3	cd05111	7.3e-05	12	304
PTKc_TrkC	cd05094	1.1e-06	12	354
PTKc_DDR2	cd05095	3.3e-08	12	292
STKc_SLK	cd06643	0.00051	12	312
PKc_MEK2	cd06649	0.00011	12	340
PKc_MEK1	cd06650	0.00079	12	340
STKc_TEY_MAPK_plant	cd07858	4.4e-05	12	355
STKc_CDK12	cd07864	5.8e-05	12	307
PTKc_EphR	cd05033	1.1e-11	13	294
PTKc_Src_like	cd05034	2e-11	13	293
PTKc_Jak_rpt2	cd05038	4.2e-13	13	294
PTKc_EphR_A	cd05066	7.4e-09	13	294
PTKc_InsR_like	cd05032	1.9e-08	13	292
PTKc_Tec_like	cd05059	2.1e-12	13	291
PTKc_Btk_Bmx	cd05113	8.3e-13	13	291
PTKc_Tec_Rlk	cd05114	1.7e-16	13	291
STKc_NAK1_like	cd06917	0.00014	13	292
PTKc_Srm_Brk	cd05148	6.3e-09	14	293
STKc_MAPKKK	cd06606	1.6e-14	14	284
STKc_MAP4K3_like	cd06613	3.3e-08	14	292
STKc_MST4	cd06640	3.4e-05	14	313
STKc_MST3	cd06641	2.2e-05	14	313
STKc_STK25-YSK1	cd06642	6e-06	14	313
STKc_MAP4K3	cd06645	0.00015	14	291
PTKc_Jak1_rpt2	cd05079	2.6e-06	15	294
PTKc_Tyk2_rpt2	cd05080	1.1e-06	15	299
STKc_MST1_2	cd06612	2.2e-05	15	284
PKc_MKK4	cd06616	1.6e-07	15	314
STKc_CDK_like	cd07829	5.5e-08	15	288
STKc_CDK1_like	cd07835	0.00086	15	307
STKc_CDK9_like	cd07840	1.6e-07	15	283
STKc_PCTAIRE_like	cd07844	6.3e-05	15	307
STKc_PCTAIRE2	cd07872	0.00069	15	334
STKc_Nek6_Nek7	cd08224	0.00018	15	296
PTKc_Jak2_Jak3_rpt2	cd05081	6.5e-10	16	294
STKc_phototropin_lik	cd05574	0.00096	16	296
STKc_PKA	cd05580	0.00053	16	260
STKc_PDK1	cd05581	1.3e-10	16	284
STKc_DMPK_like	cd05597	0.0002	16	360
STKc_LATS	cd05598	1.3e-05	16	378
STKc_MAST	cd05609	1.8e-06	16	353
STKc_PRKX_like	cd05612	0.00074	16	333
STKc_MST3_like	cd06609	3.7e-07	16	314
PKc_MEK	cd06615	6e-08	16	307
PKc_MKK3_6	cd06617	2.2e-08	16	289
PKc_MKK5	cd06619	0.00044	16	313
PKc_MAPKK_Pek1_like	cd06621	1.3e-05	16	288
PKc_MAPKK_PBS2_like	cd06622	2.3e-06	16	354
STKc_STK10_LOK	cd06644	1.8e-05	16	313
STKc_MEKK3_like_1	cd06653	9.4e-07	16	294
STKc_CdkB_plant	cd07837	4.2e-05	16	291
STKc_CDKL1_4	cd07847	3e-06	16	326
STKc_ERK1_2_like	cd07849	3.4e-05	16	329
STKc_PFTAIRE2	cd07870	0.00041	16	307
SPS1	COG0515	1.3e-26	16	489
PTKc_RET	cd05045	2.1e-05	17	297
PTKc_Csk	cd05082	1.7e-05	17	293
PTKc_Itk	cd05112	5.9e-09	17	291
PKc_STE	cd05122	2.2e-11	17	283
STKc_cPKC	cd05587	0.00026	17	366
STKc_MSK_N	cd05583	3.4e-05	17	316
STKc_GRK4_like	cd05605	0.00049	17	325
STKc_MSK1_N	cd05613	0.00074	17	299
STKc_cPKC_alpha	cd05615	0.0002	17	352
PKc_MAPKK_Byr1_like	cd06620	1.1e-08	17	307
STKc_MAPKKK_Byr2_lik	cd06628	3.5e-12	17	294
STKc_MEKK3	cd06651	1.3e-05	17	290
STKc_CCRK	cd07832	4.9e-07	17	284
STKc_MAPK	cd07834	0.00037	17	321
STKc_Pho85	cd07836	7.9e-05	17	307
STKc_CDK5	cd07839	6e-05	17	307
STKc_NLK	cd07853	0.00025	17	429
STKc_MAPK4_6	cd07854	0.00014	17	346
STKc_TDY_MAPK_plant	cd07859	8.1e-05	17	355
STKc_Nek	cd08215	2.4e-14	17	293
STKc_Nek1	cd08218	6.4e-05	17	288
STKc_Nek3	cd08219	3.4e-07	17	292
STKc_Nek8	cd08220	2.1e-07	17	294
STKc_Nek9	cd08221	2.2e-08	17	292
STKc_Nek4	cd08223	9.1e-05	17	294
STKc_Nek5	cd08225	0.00054	17	294
STKc_Nek10	cd08528	0.00013	17	290
PTKc_Axl_like	cd05035	2.3e-07	18	294
PTKc_Csk_like	cd05039	3.5e-06	18	293
PTKc_Tyro3	cd05074	6.7e-06	18	294
PTKc_Axl	cd05075	7.3e-06	18	294
PTKc_Chk	cd05083	3.3e-07	18	293
PTKc_Tie1	cd05089	3.2e-05	18	308
STKc_CMGC	cd05118	2.5e-07	18	288
STKc_PKN	cd05589	0.00012	18	360
STKc_myosinIII_like	cd06608	2.5e-06	18	293
STKc_Nek6	cd08228	0.00021	18	293
STKc_Nek7	cd08229	0.00011	18	296
PKc_MAPKK	cd06605	1.7e-09	19	289
PKc_MAPKK_plant_like	cd06623	1.8e-14	19	299
STKc_CDK10	cd07845	0.00024	19	284
STKc_FA2-like	cd08529	3.7e-08	20	294
STKc_ROCK_NDR_like	cd05573	0.00083	21	362
STKc_Yank1	cd05578	1.1e-08	21	294
STKc_RSK_N	cd05582	0.00029	21	358
STKc_MEKK4	cd06626	1.3e-08	21	274
STKc_Nek2	cd08217	2.7e-06	21	293
STKc_CNK2-like	cd08530	1.6e-05	21	294
PTKc	cd00192	3.2e-27	22	291
PTK_Jak_rpt1	cd05037	5.2e-06	22	291
PTKc_Ack_like	cd05040	6.1e-11	22	292
PTKc_Fes_like	cd05041	1.9e-12	22	292
PTKc_Aatyk	cd05042	0.00014	22	257
PTKc_c-ros	cd05044	2e-08	22	292
PTKc_Tie	cd05047	6.2e-06	22	295
PTKc_Met_Ron	cd05058	6.8e-13	22	296
PTKc_Syk_like	cd05060	1.1e-11	22	295
PTK_Jak1_rpt1	cd05077	0.00083	22	291
PTKc_Fes	cd05084	3.9e-08	22	292
PTKc_Fer	cd05085	4.4e-08	22	292
PTKc_Aatyk1_Aatyk3	cd05087	0.00079	22	292
PTKc_Syk	cd05116	9.2e-08	22	299
STKc_PKB	cd05571	1.2e-05	22	365
STKc_PKC	cd05570	0.00057	22	303
STKc_aPKC	cd05588	2.3e-05	22	379
STKc_nPKC_epsilon	cd05591	6.5e-05	22	352
STKc_nPKC_theta_delt	cd05592	2.3e-05	22	358
STKc_nPKC_theta	cd05619	7.5e-06	22	353
STKc_MEKK3_like	cd06625	1.5e-09	22	292
STKc_Cdc7_like	cd06627	4.3e-10	22	274
STKc_MEKK1_plant	cd06632	2.4e-07	22	284
STKc_MEKK1	cd06630	1.8e-05	22	295
STKc_CDK7	cd07841	1.9e-06	22	295
STKc_Nek11	cd08222	7e-06	22	294
PTK_Ryk	cd05043	8.3e-05	23	294
STKc_beta_ARK	cd05606	0.00049	23	317
STKc_MAK_like	cd07830	7e-05	23	292
PKc	cd00180	2.1e-56	24	290
PTK_Jak2_Jak3_rpt1	cd05078	4e-05	24	291
PTKc_Zap-70	cd05115	1.5e-09	24	299
STKc_AGC	cd05123	3.4e-08	24	287
STKc_MAST_like	cd05579	8.1e-09	24	283
STKc_YPK1_like	cd05585	0.00041	24	357
STKc_Sck1_like	cd05586	0.0006	24	403
STKc_GRK1	cd05608	0.00023	24	315
STKc_SLK_like	cd06611	0.00013	24	289
STKc_YSK4	cd06631	5e-08	24	293
STKc_OSR1_SPAK	cd06610	2.7e-07	26	284
STKc_MAPKKK_Bck1_lik	cd06629	1.8e-05	26	284
STKc_CRIK	cd05601	0.00028	38	321
CARD_NOD1_CARD4	cd08324	0.0003	438	522
CARD_RIP2_CARD3	cd08786	2.2e-65	438	524
CARD	cd01671	4.2e-13	440	521
Pkinase_Tyr	pfam07714	2.8e-22	18	290
STYKc	smart00221	1e-34	18	292
TyrKc	smart00219	6.8e-20	18	290
S_TKc	smart00220	5.7e-32	28	294

Table of Mutations found on the Protein

Source ↕	Mut_ID ↕	Class ↕	HGVS ↕	Disease ↕
dbSNP	rs2230801	Polymorphism	p.ILE259THR	N/A

Please Cite: Peterson, T.A., Adadey, A., Santana-Cruz ,I., Sun, Y., Winder A, Kann, M.G., (2010) DMDM: Domain Mapping of Disease Mutations. Bioinformatics 26 (19), 2458-2459.

DMDM_info@umbc.edu | 1000 Hilltop Circle, Baltimore, MD 21250 | Department of Biological Sciences | Phone: 410-455-2258