Results for the protein: NP

Results for the Protein: NP_001004056

51873045

2868

GRK4

NCBI

G protein-coupled receptor kinase 4 isoform beta [Homo sapiens]

			0 4 0 4 0

Tips:

The Domains on the Default View are decided by the Domain's E-Value.

Clicking a check box will display or hide the correlated domain.

To view the Gene page, either click on the link to the left or the blue bar above the Protein's graphic.

RefSeq Protein: NP_001004056

Default View:

Domains found on the Protein

Domain ↕	CD Accession ↕	E-Value ↕	Start ↕	End ↕
STKc_ROCK	cd05596	7.8e-11	117	461
STKc_ROCK2	cd05621	9.2e-12	118	469
STKc_ROCK1	cd05622	7.8e-11	125	470
STKc_myosinIIIB	cd06639	2.5e-06	130	418
STKc_JNK1	cd07875	5.2e-05	130	450
STKc_PAK5	cd06658	1.6e-06	133	444
STKc_PAK_II	cd06648	4.3e-10	133	430
STKc_JNK2	cd07876	4.3e-06	133	491
STKc_PAK6	cd06659	1.8e-07	134	435
STKc_PAK4	cd06657	2e-07	135	423
STKc_p38gamma_MAPK12	cd07880	7.4e-08	135	479
STKc_myosinIIIA	cd06638	3.1e-06	136	417
STKc_ERK5	cd07855	4.1e-05	136	450
STKc_JNK	cd07850	2.6e-06	138	496
STKc_PAK	cd06614	2e-14	139	429
STKc_p38	cd07851	1e-07	139	451
STKc_PAK_I	cd06647	8.8e-06	141	442
STKc_PAK1	cd06654	1.1e-06	141	444
STKc_PAK2	cd06655	8.8e-07	141	451
STKc_PAK3	cd06656	5.9e-07	141	446
STKc_JNK3	cd07874	2e-05	141	491
STKc_STK10_LOK	cd06644	2.5e-07	142	433
STKc_MAP4K5	cd06646	1.6e-06	143	416
STKc_p38alpha_MAPK14	cd07877	0.00016	143	476
PTKc_Chk	cd05083	4.9e-06	144	413
STKc_CDK12	cd07864	1.1e-08	144	412
STKc_CDK9	cd07865	1.6e-07	144	417
STKc_ASK	cd06624	4.2e-07	145	417
STKc_MAP4K3	cd06645	8.2e-08	145	416
STKc_p38beta_MAPK11	cd07878	5.2e-05	145	479
STKc_p38delta_MAPK13	cd07879	0.00029	145	467
PKc_MKK7	cd06618	9.6e-09	146	428
STKc_TNIK	cd06637	1.4e-05	146	417
STKc_CDK10	cd07845	1.3e-07	146	435
PTKc_DDR2	cd05095	5.2e-06	147	426
PTK_HER3	cd05111	7.2e-05	147	395
PTKc_ALK_LTK	cd05036	1.3e-06	148	390
PTKc_FAK	cd05056	6.2e-05	148	413
PTKc_EGFR_like	cd05057	1.4e-05	148	395
PTKc_Tie2	cd05088	3.5e-05	148	413
PTK_CCK4	cd05046	0.00051	149	406
PTKc_Ror	cd05048	0.0001	149	363
PTKc_EphR_A2	cd05063	0.00093	149	429
PTKc_Ror1	cd05090	3.4e-05	149	428
PTKc_Ror2	cd05091	0.00058	149	428
PTKc_DDR1	cd05096	0.00093	149	426
PTKc_DDR_like	cd05097	7.5e-06	149	426
PKc_MEK2	cd06649	0.00021	149	518
PKc_MEK1	cd06650	0.00061	149	489
PTKc_InsR_like	cd05032	7.7e-05	150	427
PTKc_EphR	cd05033	0.00021	150	392
PTKc_Src_like	cd05034	2.2e-06	150	428
PTKc_Jak_rpt2	cd05038	5.2e-07	150	429
PTKc_Musk	cd05050	8.8e-05	150	414
PTKc_Abl	cd05052	0.00013	150	414
PTKc_InsR	cd05061	2.8e-06	150	422
PTKc_IGF-1R	cd05062	2.7e-05	150	413
PTKc_EphR_B	cd05065	0.0001	150	418
PTKc_EphR_A	cd05066	0.00063	150	420
PTKc_Lck_Blk	cd05067	0.00011	150	433
PTKc_Frk_like	cd05068	1.3e-07	150	408
PTKc_Yes	cd05069	1.3e-05	150	408
PTKc_Fyn_Yrk	cd05070	4.6e-05	150	385
PTKc_Hck	cd05073	0.00027	150	415
PTKc_Tyk2_rpt2	cd05080	8.7e-06	150	427
PTKc_Csk	cd05082	2.8e-05	150	408
PTKc_Lyn	cd05072	6.2e-05	150	420
PTKc_TrkC	cd05094	0.00025	150	461
PTKc_HER2	cd05109	5.7e-05	150	421
PTKc_Src	cd05071	0.00022	150	410
PTKc_EGFR	cd05108	0.00021	150	455
PTKc_Itk	cd05112	0.00015	150	415
PTKc_Btk_Bmx	cd05113	4.3e-06	150	406
PTKc_Tec_Rlk	cd05114	5.5e-06	150	426
PKc_MAPKK_Byr1_like	cd06620	1.5e-07	150	429
STKc_TEY_MAPK_plant	cd07858	1e-06	150	476
STKc_MST1_2	cd06612	8e-10	151	401
STKc_MAP4K3_like	cd06613	7.1e-11	151	416
PKc_MKK4	cd06616	2.1e-07	151	447
STKc_MST3	cd06641	2.4e-06	151	426
STKc_STK25-YSK1	cd06642	1.2e-06	151	426
STKc_MST4	cd06640	3.4e-06	151	426
STKc_PCTAIRE_like	cd07844	4.3e-11	151	434
STKc_Sty1_Hog1	cd07856	8.6e-06	151	437
STKc_PFTAIRE1	cd07869	2.4e-05	151	429
STKc_PFTAIRE2	cd07870	7.6e-07	151	434
PTKc_Srm_Brk	cd05148	0.00011	152	428
STKc_SLK	cd06643	1e-06	152	431
STKc_MEKK2	cd06652	2.6e-05	152	414
STKc_MEKK3_like_1	cd06653	1.1e-07	152	417
STKc_ERK1_2_like	cd07849	7.3e-07	152	464
STKc_Nek6_Nek7	cd08224	3e-10	152	413
PTKc_Tie1	cd05089	0.001	153	426
STKc_ROCK_NDR_like	cd05573	1.3e-22	153	468
STKc_phototropin_lik	cd05574	7.7e-23	153	443
STKc_PKA	cd05580	1e-50	153	455
STKc_PDK1	cd05581	6.4e-42	153	417
STKc_DMPK_like	cd05597	1.7e-36	153	486
STKc_NDR_like	cd05599	4e-14	153	498
STKc_Sid2p_Dbf2p	cd05600	5.2e-16	153	492
STKc_CRIK	cd05601	3.6e-16	153	472
STKc_MAST	cd05609	2.9e-32	153	448
STKc_LATS	cd05598	4.3e-15	153	472
STKc_PRKX_like	cd05612	1.9e-49	153	453
STKc_MRCK_alpha	cd05623	5.8e-18	153	482
STKc_MRCK_beta	cd05624	3.9e-21	153	481
STKc_LATS1	cd05625	3e-11	153	472
STKc_LATS2	cd05626	1.5e-09	153	494
STKc_NDR2	cd05627	6.3e-09	153	506
STKc_NDR1	cd05628	4.5e-11	153	472
STKc_NDR_like_fungal	cd05629	5.3e-21	153	494
PKc_MAPKK	cd06605	6.8e-09	153	422
STKc_myosinIII_like	cd06608	4.9e-05	153	401
STKc_MST3_like	cd06609	1.4e-10	153	430
PKc_MEK	cd06615	6.2e-08	153	447
PKc_MKK3_6	cd06617	2.7e-07	153	431
PKc_MKK5	cd06619	8.6e-05	153	429
PKc_MAPKK_Pek1_like	cd06621	2.2e-06	153	417
PKc_MAPKK_PBS2_like	cd06622	1.2e-07	153	479
PKc_MAPKK_plant_like	cd06623	1.1e-16	153	410
STKc_MEKK3_like	cd06625	2.8e-12	153	417
STKc_NAK1_like	cd06917	1.4e-06	153	425
STKc_CDKL	cd07833	4.2e-07	153	417
STKc_CDKL1_4	cd07847	1.3e-08	153	452
STKc_CDKL5	cd07848	0.00046	153	435
STKc_CdkB_plant	cd07837	1.9e-11	153	418
STKc_CDK6	cd07862	0.00028	153	417
STKc_PCTAIRE3	cd07871	6.7e-08	153	434
STKc_PCTAIRE2	cd07872	1.6e-05	153	491
STKc_PCTAIRE1	cd07873	1.6e-06	153	434
STKc_Nek6	cd08228	2.6e-11	153	416
STKc_Nek7	cd08229	7.4e-12	153	415
SPS1	COG0515	1.9e-49	153	545
PTKc_RET	cd05045	6.9e-05	154	395
PKc_STE	cd05122	4.8e-18	154	416
STKc_Yank1	cd05578	2.3e-67	154	417
STKc_MSK_N	cd05583	1.3e-66	154	436
STKc_cPKC	cd05587	6.5e-70	154	482
STKc_GRK4_like	cd05605	5.7e-220	154	438
STKc_MSK1_N	cd05613	2.9e-52	154	436
STKc_MSK2_N	cd05614	2.8e-50	154	480
STKc_cPKC_alpha	cd05615	3.2e-56	154	482
STKc_cPKC_beta	cd05616	1.2e-54	154	482
STKc_GRK6	cd05630	2.9e-213	154	438
STKc_GRK5	cd05632	1.1e-216	154	438
STKc_GRK4	cd05631	1.4e-252	154	438
STKc_MAPKKK	cd06606	4e-29	154	417
STKc_Cdc7_like	cd06627	1.2e-11	154	417
STKc_MAPKKK_Byr2_lik	cd06628	1.8e-11	154	417
STKc_MEKK1_plant	cd06632	2.6e-11	154	416
STKc_YSK4	cd06631	6.7e-07	154	417
STKc_MEKK3	cd06651	2.2e-09	154	410
STKc_CCRK	cd07832	9.8e-13	154	418
STKc_Pho85	cd07836	3.9e-08	154	452
STKc_CDK5	cd07839	1.4e-06	154	417
STKc_CDK7	cd07841	4.4e-10	154	404
STKc_NLK	cd07853	7.8e-05	154	493
STKc_MPK1	cd07857	1.2e-05	154	458
STKc_TDY_MAPK_plant	cd07859	8e-06	154	467
STKc_CDK2_3	cd07860	8.3e-07	154	417
STKc_CDK1_euk	cd07861	1.4e-06	154	434
STKc_CDK4	cd07863	4.2e-06	154	417
STKc_BUR1	cd07866	2e-10	154	417
STKc_Nek	cd08215	6.5e-20	154	404
STKc_Nek1	cd08218	2.6e-16	154	412
STKc_Nek3	cd08219	8e-12	154	412
STKc_Nek8	cd08220	6.4e-09	154	412
STKc_Nek11	cd08222	1e-06	154	417
STKc_Nek4	cd08223	4.2e-14	154	416
STKc_Nek5	cd08225	7.8e-07	154	417
STKc_Nek10	cd08528	7e-09	154	413
STKc_FA2-like	cd08529	6.7e-10	154	401
STKc_CNK2-like	cd08530	2.3e-13	154	409
PTKc_Axl_like	cd05035	0.0002	155	409
PTKc_Tyro3	cd05074	0.00023	155	409
STKc_CMGC	cd05118	3.8e-13	155	417
STKc_PKN	cd05589	6.9e-66	155	474
STKc_MAPKKK_Bck1_lik	cd06629	2.1e-07	155	398
STKc_CDK_like	cd07829	9.8e-13	155	417
STKc_MAK_like	cd07830	1.7e-08	155	417
STKc_CDK1_like	cd07835	1.6e-07	155	417
STKc_CDK4_6_like	cd07838	2.6e-07	155	417
STKc_MAPK4_6	cd07854	0.00075	155	463
PTKc_Jak2_Jak3_rpt2	cd05081	2.9e-08	156	429
STKc_OSR1_SPAK	cd06610	2.6e-11	156	417
STKc_MEKK4	cd06626	4.4e-09	156	417
STKc_CDKL2_3	cd07846	6.9e-08	156	417
STKc_MAPK	cd07834	2e-06	157	432
STKc_CDK8_like	cd07842	0.00071	157	417
STKc_CDC2L1	cd07843	0.00019	157	417
STKc_Nek2	cd08217	1.3e-13	157	401
STKc_Nek9	cd08221	7.7e-09	157	417
STKc_RSK_N	cd05582	4.3e-57	158	474
STKc_p70S6K	cd05584	1.2e-54	158	479
STKc_MOK	cd07831	5.8e-11	158	417
STKc_CDK9_like	cd07840	3e-10	158	417
PTKc	cd00192	1.3e-10	159	402
PTKc_Ack_like	cd05040	0.00054	159	383
PTKc_Fes_like	cd05041	2.6e-07	159	390
PTKc_c-ros	cd05044	7.4e-05	159	409
PTKc_Tie	cd05047	0.00053	159	393
PTKc_Met_Ron	cd05058	7.8e-05	159	418
PTKc_Syk_like	cd05060	2.3e-05	159	375
PTKc_Fes	cd05084	2.8e-07	159	417
PTKc_Fer	cd05085	2.8e-05	159	409
PTKc_Syk	cd05116	5e-05	159	418
STKc_PKC	cd05570	5.2e-63	159	469
STKc_PKB	cd05571	2.2e-62	159	483
STKc_SGK	cd05575	1.5e-51	159	469
STKc_aPKC	cd05588	2.5e-43	159	482
STKc_nPKC_epsilon	cd05591	1.4e-57	159	475
STKc_nPKC_theta_delt	cd05592	1.8e-61	159	476
STKc_PKB_gamma	cd05593	5.6e-47	159	482
STKc_PKB_alpha	cd05594	1.9e-48	159	487
STKc_PKB_beta	cd05595	2.2e-51	159	479
STKc_nPKC_eta	cd05590	8.7e-62	159	470
STKc_SGK1	cd05602	1.5e-40	159	471
STKc_SGK2	cd05603	2.2e-42	159	480
STKc_SGK3	cd05604	3.9e-49	159	474
STKc_aPKC_zeta	cd05617	1.6e-38	159	479
STKc_aPKC_iota	cd05618	4.1e-31	159	479
STKc_nPKC_theta	cd05619	2.1e-57	159	476
STKc_nPKC_delta	cd05620	5.7e-54	159	476
STKc_MEKK1	cd06630	2.6e-09	159	418
STKc_beta_ARK	cd05606	1.2e-88	160	437
STKc_GRK3	cd05633	1.2e-83	160	438
PKc	cd00180	1.5e-62	161	415
PTKc_Zap-70	cd05115	7.7e-05	161	412
STKc_AGC	cd05123	5.6e-112	161	417
STKc_cGK_PKG	cd05572	1.1e-45	161	424
STKc_GRK	cd05577	6.4e-210	161	437
STKc_MAST_like	cd05579	9.8e-33	161	422
STKc_YPK1_like	cd05585	8e-63	161	473
STKc_Sck1_like	cd05586	4.8e-54	161	523
STKc_GRK7	cd05607	5.5e-135	161	437
STKc_GRK1	cd05608	1.3e-141	161	437
STKc_SLK_like	cd06611	7.3e-08	161	428
STKc_Rim15_like	cd05611	1.1e-14	163	423
STKc_MAPK15	cd07852	1.1e-05	203	445
RGS	pfam00615	7e-35	20	139
Pkinase	pfam00069	5.8e-70	155	417
RGS	smart00315	5.4e-32	20	139
Pkinase_Tyr	pfam07714	4.3e-12	155	392
TyrKc	smart00219	1.1e-12	155	424
STYKc	smart00221	9.6e-71	155	417
S_TKc	smart00220	5.2e-83	165	417
S_TK_X	smart00133	1.3e-05	418	497

Table of Mutations found on the Protein

Source ↕	Mut_ID ↕	Class ↕	HGVS ↕	Disease ↕
dbSNP	rs1024323	Polymorphism	p.ALA110VAL	N/A
dbSNP	rs2960306	Polymorphism	p.ARG33LEU	N/A
dbSNP	rs1801058	Polymorphism	p.VAL454ALA	N/A
dbSNP	rs1140085	Polymorphism	p.VAL215ILE	N/A

Please Cite: Peterson, T.A., Adadey, A., Santana-Cruz ,I., Sun, Y., Winder A, Kann, M.G., (2010) DMDM: Domain Mapping of Disease Mutations. Bioinformatics 26 (19), 2458-2459.

DMDM_info@umbc.edu | 1000 Hilltop Circle, Baltimore, MD 21250 | Department of Biological Sciences | Phone: 410-455-2258