Results for the protein: NP

Results for the Protein: NP_001004057

51873047

2868

GRK4

NCBI

G protein-coupled receptor kinase 4 isoform gamma [Homo sapiens]

			0 4 0 4 0

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RefSeq Protein: NP_001004057

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Domains found on the Protein

Domain ↕	CD Accession ↕	E-Value ↕	Start ↕	End ↕
STKc_ROCK	cd05596	7.8e-11	149	493
STKc_ROCK2	cd05621	9.2e-12	150	501
STKc_ROCK1	cd05622	7.8e-11	157	502
STKc_myosinIIIB	cd06639	2.5e-06	162	450
STKc_JNK1	cd07875	5.2e-05	162	482
STKc_PAK_II	cd06648	4.3e-10	165	462
STKc_PAK5	cd06658	1.6e-06	165	476
STKc_JNK2	cd07876	4.9e-06	165	496
STKc_PAK6	cd06659	1.8e-07	166	467
STKc_PAK4	cd06657	2e-07	167	455
STKc_p38gamma_MAPK12	cd07880	7.4e-08	167	511
STKc_myosinIIIA	cd06638	3.1e-06	168	449
STKc_ERK5	cd07855	4.1e-05	168	482
STKc_JNK	cd07850	3.1e-06	170	520
STKc_PAK	cd06614	2e-14	171	461
STKc_p38	cd07851	1e-07	171	483
STKc_PAK_I	cd06647	8.8e-06	173	474
STKc_PAK1	cd06654	1.1e-06	173	476
STKc_PAK2	cd06655	8.8e-07	173	483
STKc_PAK3	cd06656	5.9e-07	173	478
STKc_JNK3	cd07874	4.1e-05	173	523
STKc_STK10_LOK	cd06644	2.5e-07	174	465
STKc_MAP4K5	cd06646	1.6e-06	175	448
STKc_p38alpha_MAPK14	cd07877	0.00016	175	508
PTKc_Chk	cd05083	4.9e-06	176	445
STKc_CDK9	cd07865	1.6e-07	176	449
STKc_CDK12	cd07864	1.1e-08	176	444
STKc_ASK	cd06624	4.2e-07	177	449
STKc_MAP4K3	cd06645	8.2e-08	177	448
STKc_p38beta_MAPK11	cd07878	5.2e-05	177	511
STKc_p38delta_MAPK13	cd07879	0.00029	177	499
PKc_MKK7	cd06618	9.6e-09	178	460
STKc_TNIK	cd06637	1.4e-05	178	449
STKc_CDK10	cd07845	1.3e-07	178	467
PTKc_DDR2	cd05095	5.2e-06	179	458
PTK_HER3	cd05111	7.2e-05	179	427
PTKc_ALK_LTK	cd05036	1.3e-06	180	422
PTKc_FAK	cd05056	6.2e-05	180	445
PTKc_EGFR_like	cd05057	1.4e-05	180	427
PTKc_Tie2	cd05088	3.5e-05	180	445
PTK_CCK4	cd05046	0.00051	181	438
PTKc_Ror	cd05048	0.0001	181	395
PTKc_EphR_A2	cd05063	0.00093	181	461
PTKc_Ror1	cd05090	3.4e-05	181	460
PTKc_Ror2	cd05091	0.00058	181	460
PTKc_DDR1	cd05096	0.00093	181	458
PTKc_DDR_like	cd05097	7.5e-06	181	458
PKc_MEK1	cd06650	0.00048	181	516
PKc_MEK2	cd06649	0.00016	181	526
PTKc_InsR_like	cd05032	7.7e-05	182	459
PTKc_Src_like	cd05034	2.2e-06	182	460
PTKc_EphR	cd05033	0.00021	182	424
PTKc_Jak_rpt2	cd05038	5.2e-07	182	461
PTKc_Musk	cd05050	8.8e-05	182	446
PTKc_Abl	cd05052	0.00013	182	446
PTKc_InsR	cd05061	2.8e-06	182	454
PTKc_IGF-1R	cd05062	2.7e-05	182	445
PTKc_EphR_B	cd05065	0.0001	182	450
PTKc_EphR_A	cd05066	0.00063	182	452
PTKc_Lck_Blk	cd05067	0.00011	182	465
PTKc_Frk_like	cd05068	1.3e-07	182	440
PTKc_Yes	cd05069	1.3e-05	182	440
PTKc_Fyn_Yrk	cd05070	4.6e-05	182	417
PTKc_Src	cd05071	0.00022	182	442
PTKc_Hck	cd05073	0.00027	182	447
PTKc_Lyn	cd05072	6.2e-05	182	452
PTKc_Tyk2_rpt2	cd05080	8.7e-06	182	459
PTKc_Csk	cd05082	2.8e-05	182	440
PTKc_TrkC	cd05094	0.00025	182	493
PTKc_EGFR	cd05108	0.00021	182	487
PTKc_HER2	cd05109	5.7e-05	182	453
PTKc_Itk	cd05112	0.00015	182	447
PTKc_Btk_Bmx	cd05113	4.3e-06	182	438
PTKc_Tec_Rlk	cd05114	5.5e-06	182	458
PKc_MAPKK_Byr1_like	cd06620	1.5e-07	182	461
STKc_TEY_MAPK_plant	cd07858	1e-06	182	508
STKc_MST1_2	cd06612	8e-10	183	433
STKc_MAP4K3_like	cd06613	7.1e-11	183	448
PKc_MKK4	cd06616	2.1e-07	183	479
STKc_MST3	cd06641	2.4e-06	183	458
STKc_STK25-YSK1	cd06642	1.2e-06	183	458
STKc_MST4	cd06640	3.4e-06	183	458
STKc_PCTAIRE_like	cd07844	4.3e-11	183	466
STKc_Sty1_Hog1	cd07856	8.6e-06	183	469
STKc_PFTAIRE1	cd07869	2.4e-05	183	461
STKc_PFTAIRE2	cd07870	7.6e-07	183	466
PTKc_Srm_Brk	cd05148	0.00011	184	460
STKc_SLK	cd06643	1e-06	184	463
STKc_MEKK2	cd06652	2.6e-05	184	446
STKc_MEKK3_like_1	cd06653	1.1e-07	184	449
STKc_ERK1_2_like	cd07849	7.3e-07	184	496
STKc_Nek6_Nek7	cd08224	3e-10	184	445
PTKc_Tie1	cd05089	0.001	185	458
STKc_ROCK_NDR_like	cd05573	1.3e-22	185	500
STKc_phototropin_lik	cd05574	7.7e-23	185	475
STKc_PKA	cd05580	1e-50	185	487
STKc_PDK1	cd05581	6.4e-42	185	449
STKc_LATS	cd05598	4.3e-15	185	504
STKc_DMPK_like	cd05597	3.5e-36	185	518
STKc_NDR_like	cd05599	4.6e-14	185	504
STKc_Sid2p_Dbf2p	cd05600	5.4e-16	185	502
STKc_CRIK	cd05601	3.6e-16	185	504
STKc_PRKX_like	cd05612	1.9e-49	185	485
STKc_MAST	cd05609	2.9e-32	185	480
STKc_MRCK_alpha	cd05623	5.8e-18	185	514
STKc_MRCK_beta	cd05624	3.9e-21	185	513
STKc_LATS2	cd05626	1.2e-09	185	527
STKc_NDR2	cd05627	9.4e-09	185	504
STKc_NDR1	cd05628	4.5e-11	185	504
STKc_NDR_like_fungal	cd05629	1e-19	185	526
STKc_LATS1	cd05625	3e-11	185	504
PKc_MAPKK	cd06605	6.8e-09	185	454
STKc_myosinIII_like	cd06608	4.9e-05	185	433
STKc_MST3_like	cd06609	1.4e-10	185	462
PKc_MEK	cd06615	6.2e-08	185	479
PKc_MKK3_6	cd06617	2.7e-07	185	463
PKc_MKK5	cd06619	8.6e-05	185	461
PKc_MAPKK_Pek1_like	cd06621	2.2e-06	185	449
PKc_MAPKK_PBS2_like	cd06622	1.2e-07	185	511
PKc_MAPKK_plant_like	cd06623	1.1e-16	185	442
STKc_MEKK3_like	cd06625	2.8e-12	185	449
STKc_NAK1_like	cd06917	1.4e-06	185	457
STKc_CdkB_plant	cd07837	1.9e-11	185	450
STKc_CDKL	cd07833	4.2e-07	185	449
STKc_CDKL1_4	cd07847	1.3e-08	185	484
STKc_CDKL5	cd07848	0.00046	185	467
STKc_CDK6	cd07862	0.00028	185	449
STKc_PCTAIRE3	cd07871	6.7e-08	185	466
STKc_PCTAIRE2	cd07872	1.8e-05	185	474
STKc_PCTAIRE1	cd07873	1.6e-06	185	466
STKc_Nek6	cd08228	2.6e-11	185	448
STKc_Nek7	cd08229	7.4e-12	185	447
SPS1	COG0515	2.4e-44	185	531
PTKc_RET	cd05045	6.9e-05	186	427
PKc_STE	cd05122	4.8e-18	186	448
STKc_Yank1	cd05578	2.3e-67	186	449
STKc_MSK_N	cd05583	1.3e-66	186	468
STKc_cPKC	cd05587	6.5e-70	186	514
STKc_GRK4_like	cd05605	5.7e-220	186	470
STKc_MSK1_N	cd05613	2.9e-52	186	468
STKc_MSK2_N	cd05614	2.8e-50	186	512
STKc_cPKC_alpha	cd05615	3.2e-56	186	514
STKc_cPKC_beta	cd05616	1.2e-54	186	514
STKc_GRK6	cd05630	2.9e-213	186	470
STKc_GRK5	cd05632	1.1e-216	186	470
STKc_GRK4	cd05631	1.4e-252	186	470
STKc_MAPKKK	cd06606	4e-29	186	449
STKc_Cdc7_like	cd06627	1.2e-11	186	449
STKc_MAPKKK_Byr2_lik	cd06628	1.8e-11	186	449
STKc_YSK4	cd06631	6.7e-07	186	449
STKc_MEKK3	cd06651	2.2e-09	186	442
STKc_MEKK1_plant	cd06632	2.6e-11	186	448
STKc_CCRK	cd07832	9.8e-13	186	450
STKc_Pho85	cd07836	3.9e-08	186	484
STKc_CDK5	cd07839	1.4e-06	186	449
STKc_CDK7	cd07841	4.4e-10	186	436
STKc_NLK	cd07853	0.00027	186	524
STKc_TDY_MAPK_plant	cd07859	8e-06	186	499
STKc_CDK2_3	cd07860	8.3e-07	186	449
STKc_CDK1_euk	cd07861	1.4e-06	186	466
STKc_CDK4	cd07863	4.2e-06	186	449
STKc_MPK1	cd07857	1.2e-05	186	490
STKc_BUR1	cd07866	2e-10	186	449
STKc_Nek	cd08215	6.5e-20	186	436
STKc_Nek1	cd08218	2.6e-16	186	444
STKc_Nek3	cd08219	8e-12	186	444
STKc_Nek8	cd08220	6.4e-09	186	444
STKc_Nek4	cd08223	4.2e-14	186	448
STKc_Nek11	cd08222	1e-06	186	449
STKc_Nek5	cd08225	7.8e-07	186	449
STKc_Nek10	cd08528	7e-09	186	445
STKc_FA2-like	cd08529	6.7e-10	186	433
STKc_CNK2-like	cd08530	2.3e-13	186	441
PTKc_Axl_like	cd05035	0.0002	187	441
PTKc_Tyro3	cd05074	0.00023	187	441
STKc_CMGC	cd05118	3.8e-13	187	449
STKc_PKN	cd05589	6.9e-66	187	506
STKc_MAPKKK_Bck1_lik	cd06629	2.1e-07	187	430
STKc_CDK_like	cd07829	9.8e-13	187	449
STKc_MAK_like	cd07830	1.7e-08	187	449
STKc_CDK1_like	cd07835	1.6e-07	187	449
STKc_CDK4_6_like	cd07838	2.6e-07	187	449
STKc_MAPK4_6	cd07854	0.00075	187	495
PTKc_Jak2_Jak3_rpt2	cd05081	2.9e-08	188	461
STKc_OSR1_SPAK	cd06610	2.6e-11	188	449
STKc_MEKK4	cd06626	4.4e-09	188	449
STKc_CDKL2_3	cd07846	6.9e-08	188	449
STKc_MAPK	cd07834	2e-06	189	464
STKc_CDK8_like	cd07842	0.00071	189	449
STKc_CDC2L1	cd07843	0.00019	189	449
STKc_Nek2	cd08217	1.3e-13	189	433
STKc_Nek9	cd08221	7.7e-09	189	449
STKc_RSK_N	cd05582	4.3e-57	190	506
STKc_p70S6K	cd05584	7.7e-55	190	522
STKc_MOK	cd07831	5.8e-11	190	449
STKc_CDK9_like	cd07840	3e-10	190	449
PTKc	cd00192	1.3e-10	191	434
PTKc_Ack_like	cd05040	0.00054	191	415
PTKc_Fes_like	cd05041	2.6e-07	191	422
PTKc_c-ros	cd05044	7.4e-05	191	441
PTKc_Tie	cd05047	0.00053	191	425
PTKc_Met_Ron	cd05058	7.8e-05	191	450
PTKc_Syk_like	cd05060	2.3e-05	191	407
PTKc_Fes	cd05084	2.8e-07	191	449
PTKc_Fer	cd05085	2.8e-05	191	441
PTKc_Syk	cd05116	5e-05	191	450
STKc_PKC	cd05570	5.2e-63	191	501
STKc_PKB	cd05571	2.2e-62	191	515
STKc_SGK	cd05575	1.5e-51	191	501
STKc_aPKC	cd05588	2.5e-43	191	514
STKc_nPKC_eta	cd05590	8.7e-62	191	502
STKc_nPKC_epsilon	cd05591	1.4e-57	191	507
STKc_nPKC_theta_delt	cd05592	1.8e-61	191	508
STKc_PKB_gamma	cd05593	5.6e-47	191	514
STKc_PKB_alpha	cd05594	9.4e-48	191	519
STKc_PKB_beta	cd05595	2.2e-51	191	511
STKc_SGK1	cd05602	1.5e-40	191	503
STKc_SGK2	cd05603	2.2e-42	191	512
STKc_SGK3	cd05604	3.9e-49	191	506
STKc_aPKC_zeta	cd05617	1.6e-38	191	511
STKc_aPKC_iota	cd05618	4.1e-31	191	511
STKc_nPKC_theta	cd05619	2.1e-57	191	508
STKc_nPKC_delta	cd05620	5.7e-54	191	508
STKc_MEKK1	cd06630	2.6e-09	191	450
STKc_beta_ARK	cd05606	1.2e-88	192	469
STKc_GRK3	cd05633	1.2e-83	192	470
PKc	cd00180	1.5e-62	193	447
PTKc_Zap-70	cd05115	7.7e-05	193	444
STKc_AGC	cd05123	5.6e-112	193	449
STKc_cGK_PKG	cd05572	1.1e-45	193	456
STKc_GRK	cd05577	6.4e-210	193	469
STKc_MAST_like	cd05579	9.8e-33	193	454
STKc_YPK1_like	cd05585	8e-63	193	505
STKc_Sck1_like	cd05586	3.7e-44	193	531
STKc_GRK7	cd05607	5.5e-135	193	469
STKc_GRK1	cd05608	1.3e-141	193	469
STKc_SLK_like	cd06611	7.3e-08	193	460
STKc_Rim15_like	cd05611	1.1e-14	195	455
STKc_MAPK15	cd07852	1.1e-05	235	477
RGS	pfam00615	7e-35	52	171
Pkinase	pfam00069	5.8e-70	187	449
RGS	smart00315	5.4e-32	52	171
Pkinase_Tyr	pfam07714	4.3e-12	187	424
STYKc	smart00221	9.6e-71	187	449
TyrKc	smart00219	1.1e-12	187	456
S_TKc	smart00220	5.2e-83	197	449

Table of Mutations found on the Protein

Source ↕	Mut_ID ↕	Class ↕	HGVS ↕	Disease ↕
dbSNP	rs1024323	Polymorphism	p.ALA142VAL	N/A
dbSNP	rs2960306	Polymorphism	p.ARG65LEU	N/A
dbSNP	rs1801058	Polymorphism	p.VAL486ALA	N/A
dbSNP	rs1140085	Polymorphism	p.VAL247ILE	N/A

Please Cite: Peterson, T.A., Adadey, A., Santana-Cruz ,I., Sun, Y., Winder A, Kann, M.G., (2010) DMDM: Domain Mapping of Disease Mutations. Bioinformatics 26 (19), 2458-2459.

DMDM_info@umbc.edu | 1000 Hilltop Circle, Baltimore, MD 21250 | Department of Biological Sciences | Phone: 410-455-2258