Results for the protein: P35251

Results for the Protein: P35251

56757608

5981

RFC1

NCBI, UniProt

RFC1_HUMAN RecName: Full=Replication factor C subunit 1; AltName: Full=Activator 1 140 kDa subunit; Short=A1 140 kDa subunit; AltName: Full=Activator 1 large subunit; AltName: Full=Activator 1 subunit 1; AltName: Full=DNA-binding protein PO-GA; AltName: Full=Replication factor C 140 kDa subunit; Short=RF-C 140 kDa subunit; Short=RFC140; AltName: Full=Replication factor C large subunit

			0 5 0 0 5

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Default View: Lig - COG0272 BRCT - smart00292 BRCT - cd00027 HolB - COG0470 AAA - cd00009 AAA - smart00382 RFC1 - pfam08519	Swiss-Prot Protein: P35251 Identical to: NP_001191676 Default View:

Domains found on the Protein

Domain ↕	CD Accession ↕	E-Value ↕	Start ↕	End ↕
BRCT	cd00027	9.6e-18	409	480
HolB	COG0470	1.9e-11	596	948
AAA	cd00009	3.4e-17	606	776
BRCT	smart00292	4e-16	405	482
AAA	smart00382	1.3e-10	643	778
RFC1	pfam08519	5.5e-89	915	1068

Table of Mutations found on the Protein

Source ↕	Mut_ID ↕	Class ↕	HGVS ↕	Disease ↕
Swiss-Prot	VAR_016986	Polymorphism	p.ARG613LEU	N/A
Swiss-Prot	VAR_020658	Polymorphism	p.GLN955LYS	N/A
Swiss-Prot	VAR_020657	Polymorphism	p.GLU692ASP	N/A
Swiss-Prot	VAR_014860	Polymorphism	p.ILE598VAL	N/A
Swiss-Prot	VAR_020659	Polymorphism	p.SER1146LEU	N/A

Please Cite: Peterson, T.A., Adadey, A., Santana-Cruz ,I., Sun, Y., Winder A, Kann, M.G., (2010) DMDM: Domain Mapping of Disease Mutations. Bioinformatics 26 (19), 2458-2459.

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