Results for the protein: O14578

Results for the Protein: O14578

57015279

11113

CIT

NCBI, UniProt

CTRO_HUMAN RecName: Full=Citron Rho-interacting kinase; Short=CRIK; AltName: Full=Serine/threonine-protein kinase 21

			0 4 0 1 3

Tips:

The Domains on the Default View are decided by the Domain's E-Value.

Clicking a check box will display or hide the correlated domain.

To view the Gene page, either click on the link to the left or the blue bar above the Protein's graphic.

Swiss-Prot Protein: O14578

Identical to: NP_009105

Default View:

Domains found on the Protein

Domain ↕	CD Accession ↕	E-Value ↕	Start ↕	End ↕
STKc_ROCK2	cd05621	4.9e-106	53	423
STKc_ROCK1	cd05622	2.2e-110	53	424
STKc_TAO1	cd06635	1.1e-05	71	360
STKc_TAO3	cd06633	0.00034	74	398
STKc_p38gamma_MAPK12	cd07880	1.1e-05	75	401
PTKc_EGFR_like	cd05057	0.001	77	379
STKc_myosinIIIA	cd06638	4e-11	77	360
STKc_myosinIIIB	cd06639	1.3e-10	77	361
STKc_PAK3	cd06656	1e-08	78	388
STKc_PAK2	cd06655	3.6e-08	78	387
STKc_CDK6	cd07862	0.00031	78	371
STKc_MAP4K4_6	cd06636	1.4e-10	79	360
STKc_PAK_II	cd06648	5.7e-10	79	379
STKc_PAK5	cd06658	2.4e-07	79	383
STKc_PAK4	cd06657	1.8e-06	79	385
STKc_PAK	cd06614	6.6e-18	80	379
STKc_TAO	cd06607	3.3e-07	81	399
STKc_TAO2	cd06634	1.3e-06	81	399
STKc_PAK_I	cd06647	4.9e-09	81	384
STKc_JNK2	cd07876	0.0002	81	460
PKc_MKK7	cd06618	1.2e-09	83	381
STKc_CDK9	cd07865	4.6e-08	83	360
STKc_PAK6	cd06659	3.9e-09	84	388
STKc_STK10_LOK	cd06644	4e-11	84	383
STKc_MAP4K3	cd06645	5.3e-16	86	359
STKc_MAP4K5	cd06646	1.5e-15	86	359
STKc_JNK	cd07850	4.1e-05	86	399
PTKc_Chk	cd05083	0.0004	87	370
PTKc_EGFR	cd05108	0.00074	87	405
STKc_ASK	cd06624	5.9e-11	88	360
STKc_p38	cd07851	3.4e-06	88	390
PTKc_InsR_like	cd05032	0.00018	89	343
PTKc_Trk	cd05049	2.1e-05	89	356
PTKc_Abl	cd05052	3.3e-06	89	364
PTKc_EphR_A2	cd05063	0.00068	89	364
PTKc_Yes	cd05069	3.7e-05	89	363
PTKc_Src	cd05071	6.1e-05	89	361
PTKc_Hck	cd05073	2e-06	89	359
PTKc_EphR_A10	cd05064	4.4e-05	89	364
PKc_MEK2	cd06649	2.7e-06	89	434
PKc_MEK1	cd06650	5.5e-05	89	438
STKc_ERK5	cd07855	1e-06	89	391
PTKc_ALK_LTK	cd05036	5.8e-06	90	340
PTKc_FAK	cd05056	5.8e-07	90	368
PTKc_EphR_B	cd05065	6.9e-05	90	364
PTKc_Lck_Blk	cd05067	3.8e-05	90	385
PTKc_Fyn_Yrk	cd05070	3.4e-05	90	363
PTKc_Lyn	cd05072	1.1e-05	90	359
PTKc_Frk_like	cd05068	7.1e-07	90	359
PTKc_Tec_Rlk	cd05114	8.3e-07	90	359
PTKc_Itk	cd05112	8.4e-05	90	359
STKc_myosinIII_like	cd06608	1.3e-14	90	360
STKc_SLK_like	cd06611	4e-10	90	371
STKc_TNIK	cd06637	7.8e-11	90	360
STKc_TEY_MAPK_plant	cd07858	2.3e-05	90	406
STKc_SLK	cd06643	3.8e-10	91	381
STKc_CDK12	cd07864	8.7e-08	91	354
STKc_MST4	cd06640	2.6e-07	92	366
STKc_MST3	cd06641	2.8e-07	92	366
STKc_STK25-YSK1	cd06642	2.9e-08	92	370
PTKc_EphR	cd05033	5.3e-05	93	364
PTKc_Src_like	cd05034	3.6e-06	93	363
PTKc_EphR_A	cd05066	0.00014	93	364
PTKc_Csk	cd05082	0.00048	93	363
PTKc_Tie2	cd05088	4.1e-05	93	365
PTKc_Btk_Bmx	cd05113	2.9e-06	93	359
STKc_MST1_2	cd06612	2.5e-18	93	360
STKc_MAP4K3_like	cd06613	2.7e-16	93	359
PKc_MKK4	cd06616	5.6e-07	93	379
PKc_MAPKK_Byr1_like	cd06620	7.4e-08	93	389
STKc_PCTAIRE_like	cd07844	1.5e-06	93	360
STKc_CDK10	cd07845	5.5e-07	93	380
STKc_CDC2L1	cd07843	6e-08	93	360
STKc_PFTAIRE2	cd07870	3.2e-05	93	360
STKc_PCTAIRE3	cd07871	1.2e-06	93	360
STKc_PCTAIRE2	cd07872	6.2e-05	93	380
STKc_PFTAIRE1	cd07869	8.7e-05	93	369
PTK_HER3	cd05111	0.00093	94	378
STKc_MEKK2	cd06652	3.7e-08	94	361
STKc_MEKK3_like_1	cd06653	1.1e-09	94	360
STKc_MEKK3_like	cd06625	1.8e-16	94	360
STKc_ERK1_2_like	cd07849	2.7e-06	94	393
STKc_Nek6_Nek7	cd08224	2.9e-09	94	365
STKc_Nek6	cd08228	3.5e-07	94	365
STKc_Nek7	cd08229	4.9e-09	94	366
PTKc_Tie1	cd05089	0.00063	95	364
PTKc_Srm_Brk	cd05148	3.8e-05	95	386
STKc_phototropin_lik	cd05574	5e-39	95	384
STKc_PDK1	cd05581	2.4e-59	95	360
STKc_ROCK_NDR_like	cd05573	5.5e-211	95	422
STKc_DMPK_like	cd05597	1.3e-133	95	422
STKc_Sid2p_Dbf2p	cd05600	2.1e-54	95	423
STKc_CRIK	cd05601	2.9e-283	95	422
STKc_NDR_like	cd05599	1e-81	95	425
STKc_PKA	cd05580	3.2e-57	95	391
STKc_MAST	cd05609	3.8e-52	95	389
STKc_PRKX_like	cd05612	2.6e-52	95	392
STKc_MRCK_alpha	cd05623	1.3e-111	95	423
STKc_MRCK_beta	cd05624	3.7e-117	95	422
STKc_NDR2	cd05627	1.2e-67	95	447
STKc_NDR_like_fungal	cd05629	4.9e-79	95	425
STKc_NDR1	cd05628	5.6e-69	95	425
STKc_LATS	cd05598	3.8e-73	95	425
PKc_MAPKK	cd06605	2.3e-13	95	365
STKc_MST3_like	cd06609	1.1e-14	95	373
PKc_MEK	cd06615	5e-10	95	372
PKc_MKK5	cd06619	1.7e-05	95	383
PKc_MAPKK_Pek1_like	cd06621	2e-09	95	380
PKc_MAPKK_plant_like	cd06623	4.8e-15	95	365
STKc_OSR1_SPAK	cd06610	4.1e-15	95	360
STKc_PAK1	cd06654	1.3e-08	95	386
PKc_MKK3_6	cd06617	1.7e-08	95	377
PKc_MAPKK_PBS2_like	cd06622	2.5e-10	95	404
STKc_NAK1_like	cd06917	3.2e-12	95	369
STKc_CDKL	cd07833	9.2e-13	95	360
STKc_CdkB_plant	cd07837	5e-11	95	361
STKc_CDKL1_4	cd07847	2.5e-08	95	360
STKc_CDKL5	cd07848	3.1e-07	95	360
STKc_CDKL2_3	cd07846	4.2e-10	95	360
STKc_Nek9	cd08221	3.1e-08	95	360
SPS1	COG0515	6.4e-59	95	539
PKc_STE	cd05122	9.9e-30	96	359
STKc_Yank1	cd05578	4.4e-47	96	360
STKc_MSK_N	cd05583	1.9e-44	96	377
STKc_cPKC	cd05587	1.1e-43	96	423
STKc_GRK4_like	cd05605	2.2e-36	96	379
STKc_MSK1_N	cd05613	9.6e-34	96	377
STKc_cPKC_alpha	cd05615	1.5e-32	96	423
STKc_MSK2_N	cd05614	2.5e-43	96	424
STKc_GRK6	cd05630	3.9e-26	96	379
STKc_GRK4	cd05631	6.4e-28	96	379
STKc_GRK5	cd05632	1.8e-28	96	379
STKc_cPKC_beta	cd05616	9.1e-30	96	423
STKc_MAPKKK	cd06606	3.6e-36	96	360
STKc_Cdc7_like	cd06627	9.1e-18	96	360
STKc_MAPKKK_Byr2_lik	cd06628	3.5e-21	96	360
STKc_YSK4	cd06631	1.8e-10	96	360
STKc_MEKK3	cd06651	7.9e-11	96	362
STKc_MAPK	cd07834	1.3e-08	96	400
STKc_CCRK	cd07832	5e-13	96	361
STKc_Pho85	cd07836	1.7e-06	96	388
STKc_CDK5	cd07839	1.3e-07	96	360
STKc_CDK7	cd07841	8.9e-11	96	369
STKc_MPK1	cd07857	2.9e-07	96	391
STKc_CDK2_3	cd07860	2.3e-06	96	360
STKc_TDY_MAPK_plant	cd07859	7.5e-06	96	406
STKc_CDK1_euk	cd07861	1.3e-06	96	360
STKc_CDK4	cd07863	7.2e-05	96	360
STKc_NLK	cd07853	3.4e-05	96	428
STKc_Nek	cd08215	1.1e-19	96	360
STKc_Nek1	cd08218	1.3e-17	96	360
STKc_Nek2	cd08217	6.6e-15	96	360
STKc_Nek3	cd08219	1.8e-15	96	360
STKc_Nek8	cd08220	1.2e-08	96	360
PK_STRAD	cd08216	7.8e-05	96	374
STKc_Nek5	cd08225	3.7e-16	96	360
STKc_Nek4	cd08223	7.7e-11	96	360
STKc_Nek11	cd08222	1.6e-06	96	360
STKc_Nek10	cd08528	1.3e-06	96	357
STKc_CNK2-like	cd08530	1.7e-13	96	360
STKc_FA2-like	cd08529	5.1e-12	96	354
PTKc_Jak_rpt2	cd05038	8.6e-09	97	364
PTKc_Jak1_rpt2	cd05079	0.00068	97	364
PTKc_Tyk2_rpt2	cd05080	0.00045	97	384
PTKc_Jak2_Jak3_rpt2	cd05081	5.1e-07	97	386
STKc_CMGC	cd05118	3e-14	97	360
STKc_p70S6K	cd05584	1.4e-53	97	424
STKc_PKN	cd05589	5.7e-45	97	422
STKc_LATS1	cd05625	4.3e-53	97	425
STKc_LATS2	cd05626	2.5e-59	97	425
STKc_CDK_like	cd07829	6.8e-16	97	360
STKc_MAK_like	cd07830	1.1e-11	97	360
STKc_MOK	cd07831	1.2e-12	97	360
STKc_CDK1_like	cd07835	1.6e-07	97	360
STKc_CDK4_6_like	cd07838	5.9e-09	97	360
STKc_CDK9_like	cd07840	7.2e-13	97	360
STKc_Sty1_Hog1	cd07856	1.4e-05	97	382
PK_STRAD_alpha	cd08227	0.00012	98	431
STKc_RSK_N	cd05582	4.1e-49	100	422
STKc_MEKK4	cd06626	3.4e-15	100	360
PTKc	cd00192	1.4e-07	101	359
PTKc_Ack_like	cd05040	5.2e-06	101	362
PTKc_Fes_like	cd05041	7.5e-08	101	343
PTKc_c-ros	cd05044	1.3e-06	101	361
PTKc_Fes	cd05084	6.9e-06	101	343
PTKc_Fer	cd05085	7.5e-06	101	343
PTKc_Syk	cd05116	0.00074	101	361
STKc_PKC	cd05570	6.9e-34	101	422
STKc_PKB	cd05571	3.5e-58	101	424
STKc_SGK	cd05575	9.7e-47	101	422
STKc_nPKC_eta	cd05590	3e-48	101	423
STKc_nPKC_epsilon	cd05591	1.3e-43	101	423
STKc_aPKC	cd05588	1.6e-41	101	423
STKc_PKB_alpha	cd05594	2.9e-41	101	425
STKc_PKB_beta	cd05595	2.4e-47	101	424
STKc_SGK1	cd05602	1.7e-44	101	424
STKc_SGK2	cd05603	1.8e-42	101	423
STKc_aPKC_zeta	cd05617	7.8e-32	101	423
STKc_nPKC_theta	cd05619	5.5e-38	101	424
STKc_nPKC_theta_delt	cd05592	1.5e-50	101	424
STKc_nPKC_delta	cd05620	6.3e-31	101	424
STKc_SGK3	cd05604	5e-44	101	424
STKc_aPKC_iota	cd05618	6.1e-30	101	423
STKc_PKB_gamma	cd05593	1.8e-40	101	428
STKc_MEKK1	cd06630	1.6e-11	101	361
STKc_beta_ARK	cd05606	1.8e-34	102	378
STKc_GRK3	cd05633	1.6e-20	102	379
STKc_MEKK1_plant	cd06632	7.2e-15	102	360
STKc_MAPKKK_Bck1_lik	cd06629	3.1e-07	102	360
STKc_BUR1	cd07866	5.2e-08	102	360
PKc	cd00180	2.1e-64	103	358
PTKc_Zap-70	cd05115	0.00019	103	360
STKc_AGC	cd05123	2e-88	103	360
STKc_cGK_PKG	cd05572	1.7e-47	103	367
STKc_GRK	cd05577	1.6e-26	103	378
STKc_Sck1_like	cd05586	2.3e-51	103	470
STKc_YPK1_like	cd05585	2.5e-55	103	421
STKc_MAST_like	cd05579	1.2e-63	103	365
STKc_GRK7	cd05607	5.1e-33	103	378
STKc_GRK1	cd05608	2.4e-32	103	378
STKc_PCTAIRE1	cd07873	4.1e-05	104	373
STKc_Rim15_like	cd05611	3.7e-19	106	366
STKc_MAPK15	cd07852	2.5e-05	145	391
C1	cd00029	7.1e-14	1363	1411
PH	cd00821	7.4e-09	1446	1561
Pkinase	pfam00069	2.7e-56	97	360
Pkinase_C	pfam00433	3.4e-10	378	425
C1_1	pfam00130	2.8e-06	1363	1414
PH	pfam00169	1e-13	1444	1563
CNH	pfam00780	3e-74	1597	1881
Pkinase_Tyr	pfam07714	2.3e-12	97	341
STYKc	smart00221	2.5e-77	97	360
TyrKc	smart00219	2.4e-09	97	360
S_TKc	smart00220	2.6e-87	107	360
S_TK_X	smart00133	2.9e-18	361	423
C1	smart00109	1.3e-11	1363	1411
PH	smart00233	1.3e-09	1444	1563
CNH	smart00036	1.1e-104	1592	1889

Table of Mutations found on the Protein

Source ↕	Mut_ID ↕	Class ↕	HGVS ↕	Disease ↕
Swiss-Prot	VAR_040418	Polymorphism	p.ARG9GLN	N/A
Swiss-Prot	VAR_040417	Polymorphism	p.GLY7GLU	N/A
dbSNP	rs56303497	Polymorphism	p.ILE1681VAL	N/A
Swiss-Prot	VAR_040419	Polymorphism	p.LEU183PHE	N/A

Please Cite: Peterson, T.A., Adadey, A., Santana-Cruz ,I., Sun, Y., Winder A, Kann, M.G., (2010) DMDM: Domain Mapping of Disease Mutations. Bioinformatics 26 (19), 2458-2459.

DMDM_info@umbc.edu | 1000 Hilltop Circle, Baltimore, MD 21250 | Department of Biological Sciences | Phone: 410-455-2258